Evidence Based Practice Article Review
Instructions:
Select an Evidence Based Practice journal article and summarize the main points of information
requested below. Submit requested documents to the appropriate drop box by posted deadline.
Your chosen article must be:
Nursing Practice relatable, published within the last 5 years, published from a Nursing or
Medical journal or similar resource (ex. Nursing blogs are not appropriate for this assignment),
full article (not just the abstract). There are many free journal articles online or available via the
Angelina College online library resources. It is not necessary to pay for access to an article.
Article Title:
Trans-radial approach versus trans-femoral approach in patients with acute coronary syndrome
undergoing percutaneous coronary intervention: An updated meta-analysis of randomized
controlled trials
Author(s):
Nagendra Boopathy Senguttuvan, Pothireddy M. K. Reddy, PunatiHari Shankar, Rizwan
Suliankatchi Abdulkader, Hanumath Prasad YallankiI D, Ashish Kumar, Monil Majmundar,
Vadivelu Ramalingam, Ravindran Rajendran, Kesavamoorthy Bhoopalan, Dhamodharan
Kaliyamoorthy10, Muralidharan T. R., Ankur KalraI, Ramamoorthi Jayaraj, Sivasubramanian
Ramakrishnan, Ramesh Daggubati14, Sadagopan Thanikachalam, Ashok Seth, Vinay Kumar
Bahl
Source and Publication Date:
PLoS ONE, https://doi-org.ezproxy.angelina.edu/10.1371/journal.pone.0266709
April 2022
General Summary (Minimum of 200 words):
In the study it was shown that the trans-radial approach (TRA), as opposed to the
trans-femoral approach (TFA), is linked with significantly lower 1-month all-cause mortality in
patients with acute coronary syndrome (ACS). Major bleeding, vascular complications, net
adverse clinical events (NACE), and major adverse cardiac or cerebrovascular events (MACE)
were decreased as a result of the TRA. Stroke, re-infarction, and excessive bleeding demanding
blood donations were not different between the two groups. The TRA ought to be the
recommended vascular contact in patients suffering from ACS, the authors suggest.
According to the study's findings, the trans-radial group saw much lower mortality than
the trans-femoral group. The trans-radial group significantly outperformed the trans-femoral
group in terms of the secondary outcome of major adverse cardiac or cerebrovascular events,
according to the research. Additionally, compared to the trans-femoral group, the trans-radial
group had a lower incidence of pseudoaneurysms. These findings imply that in patients with
ACS having a PCI, the trans-radial technique is preferable to the trans-femoral route. Patients
who have TRA will more likely result in sooner ambulation and this will promote reduced time
during the recovery process. This is a significant discovery since it affects how patients with
ACS are treated. A decreased mortality rate, in addition to a lower occurrence of MACE and
pseudoaneurysms, are all linked to the trans-radial method. This shows that patients with ACS
undergoing PCI should use the trans-radial technique as their preferred method.
Important Statistics or Findings Mentioned:
All-cause death at 30 days was the study's main endpoint, and the findings revealed that
death was meaningfully lesser in the trans-radial group than the intersex group (1.7% vs. 2.3%; P
= 0.004; I2 = 0%; RR: 0.75; 95% CI: 0.62-0.91). The trans-radial group significantly
outperformed the trans-femoral group in terms of the secondary results of MACE, according to
the research (P = 0.004; I2 = 0%; RR: 0.71; 95% CI: 0.56-0.90). In addition, the trans-radial
group experienced a lower rate of pseudoaneurysms than the trans-femoral group (P = 0.004; I2
= 0%; RR: 0.71; 95% CI: 0.56-0.90).
Application to Nursing Practice:
There are ramifications for nursing practice in the study's findings. Patients with ACS
benefit greatly from the care provided by nurses. When a patient exhibits signs of ACS, they are
frequently the initial point of contact. Additionally, nurses are crucial to the treatment of patients
undergoing PCI. They are in charge of both pre-and post-procedure assessment and treatment.
The results of this study should be known to nurses, who should promote the use of the
trans-radial method for ACS patients having PCI. Nurses should promote the trans-radial method
for PCI patients with ACS. Furthermore, nurses should inform patients and families of the
advantages of the trans-radial technique.