Defence against Disease – Key Words Fill in the blanks: A micro-organism that can potentially cause disease. A molecule that triggers an immune response; usually large, e.g. protein, polysaccharide, glycoprotein. A protein secreted by a B lymphocyte; each one is specific to a different non-self antigen. A white blood cell that causes a humoral response to infections by secreting antibodies; matures in the bone marrow. A white blood cell that causes a cellular response to infection; matures in the thymus. Term given to describe the way in which B lymphocytes produce antibodies in response to infection. Term which describes the way in which T lymphocytes respond to an antigen-presenting cell. Type of B lymphocyte which releases antibodies; formed when a B lymphocyte divides and produces clones. Type of B lymphocyte that remains dormant in the blood and recognises antigens if they enter the blood again so that antibody-producing cells are produced faster than before. A ‘self’ cell that has been infected; now has the pathogen’s antigens on its cell surface. Chemicals released to help phagocytes squeeze through gaps in the capillary walls. Organelles present in large amounts inside phagocytes; contain enzymes to digest the pathogen. Type of white blood cell that ingests and digests pathogens. Term given to process involving phagocytes. 1. 2. 3. 4. 5. 6. 7. Non-specific inflammatory response 8. Antigen Histamines 9. T Lymphocyte Antibody 10. Phagocyte Pathogen 11. Plasma cell Memory cell 12. Humoral response Lysosomes 13. Antigen-presenting cell B Lymphocyte 14. Cellular response Defence against Disease – Key Words Match each description to a word/term in the box below. A micro-organism that can potentially cause disease. Pathogen A molecule that triggers an immune response; usually large, e.g. protein, polysaccharide, glycoprotein. Antigen A protein secreted by a B lymphocyte; each one is specific to a different non-self antigen. Antibody A white blood cell that causes a humoral response to infections by secreting antibodies; matures in the bone marrow. B Lymphoctye A white blood cell that causes a cellular response to infection; matures in the thymus. T Lymphocyte Term given to describe the way in which B lymphocytes produce antibodies in response to infection. Humoral response Term which describes the way in which T lymphocytes respond to an antigen-presenting cell. Cellular response Type of B lymphocyte which releases antibodies; formed when a B lymphocyte divides and produces clones. Plasma cell Type of B lymphocyte that remains dormant in the blood and recognise antigens if they enter the blood again so that antibody-producing cells are produced faster than before. Memory cell A ‘self’ cell that has been infected; now has the pathogen’s antigens on its cell surface. Antigen-Presenting Cell Chemicals released to help phagocytes squeeze through gaps in the capillary walls. Histamine Organelles present in large amounts inside phagocytes; contain enzymes to digest the pathogen. Lysosomes Type of white blood cell that ingests and digests pathogens. Phagocyte Term given to process involving phagocytes. Non-specific inflammatory response