Unit 1 – Cell Structure Lesson B12.09 – Nucleus and Cytoplasm Image diameter 10mm Unit 1 – Cell Structure Lesson B12.09 – Nucleus and Cytoplasm Image diameter 10mm Learning Intentions I can describe and explain the structure of the cell membrane. I can describe and explain the structure of the nucleus. I can describe and explain the structure of the mitochondria. Cell surface mebrane Extremely thin (7nm) At high magnification – three layers Controls exchange between cell and environment. More in chapter 4 Microvilli Singular microvillus Finger like extensions Typical on animal epithelial cells Increase surface area Knowledge check What is the purpose of microvilli and where are they commonly found? What are the three layers of the cell surface membrane? Nucleus Largest cell organelle Nuclear Envelope Two membranes – together the nuclear envelope Outer is continuous with the endoplasmic reticulum Many nuclear pores – allow and control exchange of substances between nucleus and cytoplasm e.g mRNA, tRNA and ribosomes leave; proteins, nucleotides, ATP and hormones enter. Chromosomes and Chromatin Nucleus contains chromosomes. DNA in sections, genes, control activities of cell. DNA 2m long, folded round histones. DNA + proteins = chromatin. Chromatin also contains some RNA. Chromosomes are made of chromatin. Nucleolus Darkly stained rounded structure. May be more than one. Makes ribosomes using information in own DNA. Contains core of DNA from one or more chromosomes with the genes that code for rRNA. Also genes for tRNA. Around core ribosomal subunits are manufactured combining rRNA with ribosomal proteins from cytoplasm. Different parts of nucleolus only come together during ribosome synthesis. During nuclear division this ceases and the nucleolus disappears. Keywords Nuclear envelope Nuclear pores Nuclear envelope Chromatin Chromosome Knowledge check Highlight some differences between chromosome and chromatin. What is the purpose of the nuclear pore and what are some substances than commonly pass? What occurs in the nucleolus? Why does the nucleolus disappear during cell division? Mitochondria Singular mitochondrion 1micrometer length – various shapes Two membranes: inner folded into cristae (sing crista) projecting into internal space – matrix. Space between – intermembrane space Mitochondria function Carry out aerobic respiration Additionally some lipid synthesis Energy released from carbohydrates and fats and transferred to ATP (adenosine triphosphate). Energy is released elsewhere by breaking down ATP to ADP (adenosine diphosphate) Cells high demand for energy – more mitochondria (muscle, liver) Respiration reactions take place in matrix and inner membrane; matrix contains enzymes for this Endosymbiont theory Mitochondria and chloroplast contain ribosomes slightly smaller than those in cytoplasm, as well as small circular DNA (like bacteria). Mitochondria and chloroplasts are ancient bacteria now living inside larger plant and animal cells. They can no longer live independently but their DNA is still active for vital proteins. Keywords Endosymbiosis Mitochondria Matrix Cristae ATP Knowledge check Why when you exercise would your muscle cells make more mitochondria? Why is ATP referred to as the universal energy carrier? What evidence made scientists begin looking into endosymbiont theory? Learning Intentions I can describe and explain the structure of the cell membrane. I can describe and explain the structure of the nucleus. I can describe and explain the structure of the mitochondria. Plenary Make a first attempt at this quiz.