qwertyuiopasdfghjklzxcvbnmqwertyui opasdfghjklzxcvbnmqwertyuiopasdfgh jklzxcvbnmqwertyuiopasdfghjklzxcvb ALLAMA IQBAL OPEN UNIVERSITY nmqwertyuiopasdfghjklzxcvbnmqwer LAB Organization ,Management & Safety Methods (698) tyuiopasdfghjklzxcvbnmqwertyuiopas SUBMITTED TO ___SIR, ABDULLAH KHAN SUBMITTED BY ___ AHSAN ALI dfghjklzxcvbnmqwertyuiopasdfghjklzx STUDENT ID___0000123006 SEMESTER ____SPRING 2022 cvbnmqwertyuiopasdfghjklzxcvbnmq wertyuiopasdfghjklzxcvbnmqwertyuio pasdfghjklzxcvbnmqwertyuiopasdfghj klzxcvbnmqwertyuiopasdfghjklzxcvbn mqwertyuiopasdfghjklzxcvbnmqwerty uiopasdfghjklzxcvbnmqwertyuiopasdf ghjklzxcvbnmqwertyuiopasdfghjklzxc vbnmqwertyuiopasdfghjklzxcvbnmrty uiopasdfghjklzxcvbnmqwertyuiopasdf ghjklzxcvbnmqwertyuiopasdfghjklzxc vbnmqwertyuiopasdfghjklzxcvbnmqw ertyuiopasdfghjklzxcvbnmqwertyuiop 14-Aug-22 [Type the author name] Course: Lab Organization, Management & Safety Methods (698) Semester: Spring, 2022 Q.1 Keeping in view rules for storage of Chemicals write the conditions or chemicals where these substances should not be stored: Cetic acid Acetic acid should not be sorted or stored with: Nitric acid. Hydroxyl compounds. Ethylene glycol. Perchloric acid. Ammonium nitrate Where the presence of drains, etc is unavoidable, they should be protected so that molten ammonium nitrate cannot run into them. Locate storage away from possible sources of heat, fire or explosion, such as oil storage, gas pipelines, timber yards, flammable liquids, flammable solids and combustible materials. Arsenic compound Arsenic cannot be destroyed within its surroundings. It undergoes modifications of its type or combines or separates from particles. The most relevant case of As toxicity by food occurred within the western areas of Japan (Kinki, Chugoku, Shikoku, and Kyushu) in 1955. These compounds were accidentally mixed into Morinaga's dried milk, made by the Tokushima plant of the Morinaga Milk Company. Azides Store synthesized azides below room temperature and away from sources of heat, light, pressure, and shock. Store SAZ (solid as well as solutions) away from bromine, carbon disulfide, dimethyl sulfate, nitric acid, heavy metals and their salts. Chlorates Do not store perchloric acid near or in contact with combustible materials such as cotton, wood, excelsior, paper, burlap, rags, grease, oil, or organic compounds. Perchloric acid must be stored separately in a deep glass tray with sufficient capacity to hold the entire contents in case of breakage. Chlorine should not be stored with ammonia, acetylene, benzene, butadiene, hydrogen, any petroleum gases, sodium carbide or turpentine Carbon Carbon is sequestered in soil by plants through photosynthesis and can be stored as soil organic carbon (SOC). Agroecosystems can degrade and deplete the SOC levels but this carbon deficit opens 2 Course: Lab Organization, Management & Safety Methods (698) Semester: Spring, 2022 up the opportunity to store carbon through new land management practices. Soil can also store carbon as carbonates. flammable liquids Flammable liquids shall not be stored in areas used for exits, stairways, or normally used for the safe passage of people. "Indoor storage of flammable liquids." No more than 25 gallons of flammable liquids shall be stored in a room outside of an approved storage cabinet. Hydrocarbons There are two common options for above ground hydrocarbon storage, Tank and Bund and Double Walled/Skinned Tanks. Both have certain benefits and shortcomings which are summarised below. Hydrocarbons can be stored in below-ground tanks, this is the topic for another InSight. Hydrofluoric acids Do not store HF waste in glass or metal containers. Medical personnel should be warned about the HF, and a copy of SDS must be provided to them. All exposure or contact with HF shall receive immediate first aid and medical evaluation even if the injury appears minor, or there is no sense of pain Dimethylesulphoxide (DMSO) If there is no degradation while dissolving DMSO, you can store the solution in a refrigerator. Freezing might cause crystallizing your compound Q.2 Visit two laboratories. Find the system of locating items or chemicals from different locations of stored materials. before we start rounding up bottles of chemicals and reorganizing our labs, we need to make sure we have the proper PPE. At a minimum, this should include appropriate chemical-resistant gloves and eye protection, closed-toe shoes (essential for working in the laboratory), and lab coats and/or chemical aprons (used when needed or when required by your laboratory safety policy). Once we have collected our PPE, there are just a couple more things to gather before we begin moving those chemical containers around. Survey your surroundings, and take notice of any potential trip hazards and locations of work stations where others are busy. Make sure exits, passageways, and emergency equipment areas (i.e., eyewash and safety showers) are clear and free of stored materials. Locate and have close at hand a full spill kit with appropriate absorbent materials, neutralizing agents, cleanup utensils, and waste containers. Here are our pointers for moving chemicals safely: 3 Course: Lab Organization, Management & Safety Methods (698) Semester: Spring, 2022 Never move visibly degrading chemicals and containers. Report these to your lab supervisor or principle investigator. Whenever transporting chemicals, place bottles in appropriate, leak-proof secondary containers to protect against breakage and spillage. A good example is using a special plastic tote for carrying four-liter glass bottles of corrosives or solvents. When moving multiple, large, or heavy containers, use sturdy carts. Ensure cart wheels are large enough to roll over uneven surfaces without tipping or stopping suddenly. If carts are used for secondary containment make sure the trays are liquid-tight and have sufficient lips on all four sides. Do not transport chemicals during busy times such as break times or (for those academic laboratories) lunch periods or class changes. Use freight elevators for moving hazardous chemicals whenever possible to avoid potential incidents on crowded passenger elevators. Remember to remove gloves when pushing elevator buttons or opening doors. Never leave chemicals unattended. Safely storing chemicals in a laboratory or stockroom requires diligence and careful consideration. Correct use of containers and common lab equipment is critical. To store chemicals safely, DO the following; Label all chemical containers fully. We recommend including the owner’s or user’s name along with the date received. Provide a specific storage space for each chemical, and ensure return after each use. Store volatile toxics and odoriferous chemicals in ventilated cabinets. Please check with your environmental health and safety personnel for specific guidance. Store flammable liquids in approved flammable liquid storage cabinets. Small amounts of flammable liquids may be stored in the open room. Check with your local authority (e.g., fire marshal, EH&S personnel) for allowable limits. Separate all chemicals, especially liquids, according to compatible groups. Follow all precautions regarding storage of incompatible materials. Post a chemical compatibility chart for reference, both in the lab and next to chemical storage rooms. Use appropriate resistant secondary containers for corrosive materials. This protects the cabinets and will catch any leaks or spills due to breakage. 4 Course: Lab Organization, Management & Safety Methods (698) Semester: Spring, 2022 Seal containers tightly to prevent the escape of vapors. Use designated refrigerators for storing chemicals. Label these refrigerators CHEMICAL STORAGE ONLY—NO FOOD. Never store flammable liquids in a refrigerator unless it is specifically designed and approved for such storage. Use only explosion-proof (spark-free) refrigerators for storing flammables. Q.3 Write the uses of following in science laboratory: Galvanometer A galvanometer is an electromechanical measuring instrument for electric current. Early galvanometers were uncalibrated, but improved versions, called ammeters, were calibrated and could measure the flow of current more precisely. A galvanometer works by deflecting a pointer in response to an electric current flowing through a coil in a constant magnetic field. Galvanometers can be thought of as a kind of actuator. Galvanometers came from the observation, first noted by Hans Christian Ørsted in 1820, that a magnetic compass's needle deflects when near a wire having electric current. They were the first instruments used to detect and measure small amounts of current. André-Marie Ampère, who gave mathematical expression to Ørsted's discovery, named the instrument after[1] the Italian electricity researcher Luigi Galvani, who in 1791 discovered the principle of the frog galvanoscope – that electric current would make the legs of a dead frog jerk. Galvanometers have been essential for the development of science and technology in many fields. For example, in the 1800s they enabled long-range communication through submarine cables, such as the earliest transatlantic telegraph cables, and were essential to discovering the electrical activity of the heart and brain, by their fine measurements of current. Galvanometers have also been used as the display components of other kinds of analog meters (e.g., light meters and VU meters), capturing the outputs of these meters' sensors. Today, the main type of galvanometer still in use is the D'Arsonval/Weston type. Modern galvanometers, of the D'Arsonval/Weston type, are constructed with a small pivoting coil of wire, called a spindle, in the field of a permanent magnet. The coil is attached to a thin pointer that traverses a calibrated scale. A tiny torsion spring pulls the coil and pointer to the zero position. When a direct current (DC) flows through the coil, the coil generates a magnetic field. This field acts against the permanent magnet. The coil twists, pushing against the spring, and moves the pointer. The hand points at a scale indicating the electric current. Careful design of the pole pieces ensures that the 5 Course: Lab Organization, Management & Safety Methods (698) Semester: Spring, 2022 magnetic field is uniform so that the angular deflection of the pointer is proportional to the current. A useful meter generally contains a provision for damping the mechanical resonance of the moving coil and pointer, so that the pointer settles quickly to its position without oscillation. The basic sensitivity of a meter might be, for instance, 100 microamperes full scale (with a voltage drop of, say, 50 millivolts at full current). Such meters are often calibrated to read some other quantity that can be converted to a current of that magnitude. The use of current dividers, often called shunts, allows a meter to be calibrated to measure larger currents. A meter can be calibrated as a DC voltmeter if the resistance of the coil is known by calculating the voltage required to generate a full-scale current. A meter can be configured to read other voltages by putting it in a voltage divider circuit. This is generally done by placing a resistor in series with the meter coil. A meter can be used to read resistance by placing it in series with a known voltage (a battery) and an adjustable resistor. In a preparatory step, the circuit is completed and the resistor adjusted to produce full-scale deflection. When an unknown resistor is placed in series in the circuit the current will be less than full scale and an appropriately calibrated scale can display the value of the previously unknown resistor. These capabilities to translate different kinds of electric quantities into pointer movements make the galvanometer ideal for turning the output of other sensors that output electricity (in some form or another), into something that can be read by a human. Because the pointer of the meter is usually a small distance above the scale of the meter, parallax error can occur when the operator attempts to read the scale line that "lines up" with the pointer. To counter this, some meters include a mirror along with the markings of the principal scale. The accuracy of the reading from a mirrored scale is improved by positioning one's head while reading the scale so that the pointer and the reflection of the pointer are aligned; at this point, the operator's eye must be directly above the pointer and any parallax error has been minimized. Wheatstone bridge A Wheatstone bridge is an electrical circuit used to measure an unknown electrical resistance by balancing two legs of a bridge circuit, one leg of which includes the unknown component. The primary benefit of the circuit is its ability to provide extremely accurate measurements (in contrast with something like a simple voltage divider).[1] Its operation is similar to the original potentiometer. The Wheatstone bridge was invented by Samuel Hunter Christie (sometimes spelled "Christy") in 1833 and improved and popularized by Sir Charles Wheatstone in 1843. One of the Wheatstone bridge's initial uses was for soil analysis and comparison. 6 Course: Lab Organization, Management & Safety Methods (698) Semester: Spring, 2022 In the figure, Rx is the fixed, yet unknown, resistance to be measured. R1, R2, and R3 are resistors of known resistance and the resistance of R2 is adjustable. The resistance R2 is adjusted until the bridge is "balanced" and no current flows through the galvanometer Vg. At this point, the potential difference between the two midpoints (B and D) will be zero. Therefore the ratio of the two resistances in the known leg (R2 / R1) is equal to the ratio of the two resistances in the unknown leg (Rx / R3). If the bridge is unbalanced, the direction of the current indicates whether R2 is too high or too low. At the point of balance, Detecting zero current with a galvanometer can be done to extremely high precision. Therefore, if R1, R2, and R3 are known to high precision, then Rx can be measured to high precision. Very small changes in Rx disrupt the balance and are readily detected. Alternatively, if R1, R2, and R3 are known, but R2 is not adjustable, the voltage difference across or current flow through the meter can be used to calculate the value of Rx, using Kirchhoff's circuit laws. This setup is frequently used in strain gauge and resistance thermometer measurements, as it is usually faster to read a voltage level off a meter than to adjust a resistance to zero the voltage. Magnets Magnets have been proving its worth every day with its incredible function by making the most strenuous tasks easier. With the various uses of magnets in daily life, we can do heavy lifting which is not humanly possible to do every day. Magnets play an important role in various devices which can be a small toy or a heavy 100-ton device to pick up heavy metals. We come across magnets in various forms such as computers, MRI machines or inside some appliances which are used in the house, business or medical industry. The size can be from very small to the large giant like structures. Some magnet uses at home, in the laboratory and in daily life is provided in the points below. We might be using computers in our day to day lives but never wondered the presence of a magnet inside it. Magnetic elements present on a hard disk helps to represent computer data which is later ‘read’ by the computer to extract information. Magnets are used inside TVs, Sound speakers and radios. The small coil of wire and a magnet inside a speaker transforms the electronic signal to sound vibrations. Magnets are used inside a generator to transform mechanical energy to electrical energy where there are other kinds of motors which use magnets to change electrical energy to mechanical energy. 7 Course: Lab Organization, Management & Safety Methods (698) Semester: Spring, 2022 Electrically charged magnets can help cranes to move large metal pieces. Magnets are used in filtering machines which separates metallic ores from crushed rocks. It is also used in food processing industries for separating small metallic pieces from grains etc. Magnets are used in MRI machines which are used to create an image of the bone structure, organs, and tissues. Even magnets are used to cure cancer. At home, you use magnets when you stick a paper on the refrigerator in order to remember something. Attaching a magnetic bottle opener to the fridge can come in handy. We often use pocket a compass to find out directions when we are on a trek. The pocket compass uses a magnetic needle to point north. The dark strip on the back of debit and credit cards is of magnetic nature and are used to store data just like computers’ hard drives. Magnets can help collect all the nails which are scattered on the ground after a repair job. Forceps Forceps are hinged, handheld instruments commonly used in the medical field. Outside of the medical field, forceps-like instruments are sometimes known as tweezers, pliers, tongs, etc. What are forceps used for? Many people associate forceps with childbirth, but they have other applications as well. Forceps are typically used to grasp, hold or produce traction on an object. Forceps function as a set of levers working together. Principles of mechanical advantage determine the forceps science used to design different forceps. A greater distance from the hinge to the handle will create more mechanical advantage and be easier to open and close and will clamp with greater force. A smaller distance from the hinge to the clamps will also generate more clamping force. Forceps can be made out of plastic; these are designed to be used once and then disposed of. Repeated sterilization is required when forceps are being used for surgical purposes. These forceps need to be made out of high-grade carbon steel to be durable enough to go through repeated sterilization processes. There are two primary types of forceps: locking and non-locking forceps. Non-locking forceps open and close repeatedly controlled by simple hand motion. They can be hinged at one end and closed at the other end. Outside of medical use, this type of forceps would be called tweezers. Some non-locking forceps are hinged in the middle and look similar to scissors. Unlike scissors, the ends of the forceps are flat to grasp or hold instead of to cut. Locking forceps lock the clamping surfaces together or closed. This allows an object to remain held or grasped so that it can be easily manipulated or moved. 8 Course: Lab Organization, Management & Safety Methods (698) Semester: Spring, 2022 Q.4 What is condition of Practical Science in low income countries? Research and development (R&D) offer promising clues to address a wide range of socioeconomic problems through the development of new products and services or often by improving the existing ones. High-income countries (HICs) have realized the worth of R&D and invested tremendously in that sector; however, resource-poor low-income countries (LICs) are still far behind in realizing the potential benefit that R&D could offer for economic growth and national development. Even if some LICs have a positive outlook towards the R&D sector, the trend of emulating works from HICs to solve local or regional issues have most often yielded counterproductive results. LICs are suggested primarily to focus on applied research by incorporating their socioeconomic and cultural aspects to solve their everyday problems whose investigation is often ignored in research-intensive nations. Moreover, applied research in LICs offers the potential to provide low-cost and innovative solutions to local and regional problems with global implications. Good research drives most of the advancements across all scientific disciplines. How do we know if climate change is real? We need to conduct research: plot long-run temperature, rainfall, and carbon emissions and analyze them to determine any significant trends that might be of concern. How do we know which medications will help us feel better when we are sick? We need to conduct research, perhaps ask people to participate in double-blind trials for new medications. How do we know which fertilizer best helps a plant grow? We need to conduct research, maybe conduct randomized controlled trials under various environmental settings. The medications that we take, fertilizers that we apply in fields and even gadgets, which have become integral to our lives, were part of the investigational program in the past and we only use them because researchers have examined them and determined that they are effective and helpful for our overall betterment. R&D necessitates resource allocation in advance; however, the resulting innovations serve to reduce the costs through more efficient production processes or the product itself (Kenton, 2019). Scientific research is a pre-requisite for human and societal development. There is a strong correlation between the level of advancement of scientific research and the standard of living (Badr, 2018). Results from careful research can be utilized to create wealth, increase the nation's worth, and boost the socioeconomic and political situation of the country. Innovation through quality research and subsequent patent rights have an additive effect on a nation's wealth and positive ripple effects on the economy. For example, China succeeded in lifting its 700 million people by domestic innovations and new start-up businesses (NDRC, 2016; Trivedi, 2018). Similarly, South Korea and Israel also boosted its economy through intensive R&D and subsequent integration into the global market. South Korea presents a vivid 9 Course: Lab Organization, Management & Safety Methods (698) Semester: Spring, 2022 example of how a country, comparable with other poorer countries of Asia and Africa in 1960s, transcended to a trillion-dollar economy in 2004 by integrating R&D into their national strategy and spending more than 4% of gross domestic product (GDP) annually on R&D, with the majority being on applied research sector (Reddy, 2011). Israel is also exemplary in how a country primarily occupied by arid land succeeded to become one of the largest exporters of agricultural commodities through innovation following uninterruptible research. According to the World Bank, countries with gross national income per capita below $955 are LICs and include 33 countries (World Bank, 2016; Table 1). LICs have limited resources with most of them having a GDP size of < $500 billion and per capita GDP < $2,000 (CIA, 2019). LICs are mostly located in the southern hemisphere of the globe. While most countries in the northern hemisphere, high-income countries (HICs), have outpaced issues such as poverty and underdevelopment long ago, their counterparts in the south are still stricken with domestic conflict, poverty, malnutrition and food crisis leaving them far behind in terms of cherishing life amenities and modern infrastructural development. Keeping aside many factors influencing the success of HICs, one of them is that HICs were able to draw clues and trace a path to rapid development through timely and careful research and its subsequent development. HICs including the United States, Japan, and Great Britain, besides prospering themselves, inspired many other nations on how to identify the problems and tackle them through demand-driven research, ultimately benefiting citizens and leaving some spillovers around the globe. Today, if we look carefully at the way of living, infrastructures, ongoing innovation, national policies regarding both present and future goals and the like, we can feel that there are many small globes within our globe. Just standing somewhere in the United States, Germany, or Japan and conversely standing in Afghanistan, Somalia, or even Nepal can give a “big picture” of the vast disparity resembling completely different globes across different continents. LICs account for ~85% of the global disease burden with the majority of the population fighting against poverty-related malnutrition, infectious diseases (both airborne and waterborne), hunger, and environmental brunt like climate change, famine, water scarcity, and deforestation on a day-to-day basis (Batterman et al., 2009; Thomas, 2015). As a result, R&D is not under a government priority in LICs with investment being <1% of their GDP (Gaillard, 2010). This is unsurprising due to three reasons: First, LICs are still struggling to meet the necessities of food, clothing, and shelter of their citizens. This leaves the government with only a few surplus resources to invest in R&D. Furthermore, LICs typically finance most of their research with public funds, unlike HICs where the business sector funds most research activities. This fosters stronger 10 Course: Lab Organization, Management & Safety Methods (698) Semester: Spring, 2022 budget austerity, making it more important to understand the effect of R&D budget allocation decisions (Gonzalez-Brambila et al., 2016). Research requires substantial financial investment over a protracted period. Some pioneer research might take up to a decade or even more to get meaningful results, while some other cutting-edge research after laboratory experimentation needs validation in the field condition. All of these processes demand perseverance and continuous financial commitment over a prolonged period that is difficult to secure in LICs. Second, with more important social issues, political parties and bureaucrats in LICs believe that research is a sack into which money is poured and from which nothing of apparent value is reaped. They also perceive R&D as a waste of limited resources. This preconceived notion of political personnel and bureaucrats deters from making a proper budget allocation in the R&D sector. Instead, they focus on immediate needs having practical values: eradication of hunger, control of infectious and debilitating diseases, decrease in the unemployment rate, and raising the quality of life of their citizens, but in a conventional way. In other words, LICs are more focused on those issues that have immediate results to society and the economy as a whole. For example, the national campaign for vitamin A and polio vaccination, where simple intervention and low investment would have a greater and immediate impact saving millions of children from potential danger. Investment in such areas might seem rational over spending on R&D in the short term for them. The process of R&D is severely constrained by a small budget allocation from lack of knowledge and ignorance of that part. Third, despite some research efforts, poor implementation of research findings is another pressing issue for LICs as a result of which research findings are not clearly linked with visible output (Hoekman et al., 2003). Besides that, some research fails to address the local culture, human rights issues, language policy, and local environment and thus is not translated into applicable outcomes. In agriculture, there are several instances where local agribusinesses bypass local science and technology (S&T) systems and rely on foreign technologies as a response to new innovation elsewhere thereby leading to loss of inherent profit potential (Keskin et al., 2008). Insufficient research translates into data and knowledge gaps which are major constraints to future wellbeing and furthering development. An insufficient amount of quality research is the major impediment to growth, development, and advancement. So, raising awareness on the importance of R&D and a positive outlook towards its promising nature are very necessary Q.5 Write need and importance of practical work and science laboratory. 11 Course: Lab Organization, Management & Safety Methods (698) Semester: Spring, 2022 Learning by doing can be achieved only by doing experimentation. Any course of Science which does not period opportunities for lab work is incomplete from the point of view of efficient teaching. On every practical turn, a student must carry with him the following things to the laboratory so that he is well equipped to perform various type of experiments1. Scale, 2. Eraser, 3. A pencil, 4 Auxiliary notebooks and 5. Laboratory note-books. Important of Practical work 1. Learning by doing: Practical work follows the basic principle of Learning by doing. The students gets an opportunity to activity participate in the learning process. 2. Training for adjustment: When students know elementary things about electricity, electronics, sanitation etc. they depend less on others for minor repairs. 3. Scientific knowledge and Scientific Outlook: Practical work helps in acquiring of scientific knowledge and scientific outlook, the twin main objectives of teaching science. 4. Handing of Objects: By doing experiments students learn how to handle and operate apparatus etc. 5. Development of good habits: Through practical work the students learn many good habits like resourcefulness, initiative, cocooperation etc. 6. Satisfaction of curiosity: Validity of the concepts learned by the students can be tested by experimentation. This satisfies basic human desire of knowledge of what, how and why of things. . Development of Scientific attitude: Lab work develops scientific attitude and scientific temper. 8. Motivation: By doing experiments, students are motivated to know more and more of science. Administration of Practical-Work: 1. Procedure of Laboratory work: 12 Course: Lab Organization, Management & Safety Methods (698) Semester: Spring, 2022 The science teacher should check the availability of the apparatus required for particular experiments. Afterwards he should assure that the apparatus is ready and working condition before the students enter the laboratory. The broken apparatus is noted down in the breakage register. 2. Grouping: In some schools, same experiment is done by all the students at the same time. The teacher gives general instructions to the whole class at one instant and can cyclise form where the number of students in a class is much more each group is allotted a different experiment. The experiments are cycled in groups. This method had following limitationsa. There is every possibility that weaker students may copy the results of the brighter students. b. It may become difficult to correlate .theory and practicals for all students. c. Supply different apparatus and chemicals to different groups. 3. Guideline rules: In order to make practical work effective, the laboratory should be made a place of learning by doing. Guideline should be laid down by the teacher about the laboratory rules such as the followinga. Work area must be cleared. b. Strict attention should be paid to own work. c. Reagent stoppers should not be left on counter tops. d . Wastage of water, gas, electricity should be strictly avoided. e. Directions should be read and followed very carefully. f. Teachers should allow the student’s entry in lab in his/her presence. g. Only those experiments should be done which are recommended by the teacher-incharge. 13