University of Oregon
Human Physiology I
HPHY 322: Fall 2014
Tuesday/Thursday 12:00-1:20pm 180 PLC
Short Description: Neuro- and muscular physiology: action potentials; synapses
& receptors; skeletal muscle; central, peripheral & autonomic nervous systems;
special senses. Includes experimental laboratory (Pre-req BI 212, Pre or co-req
HPHY 321).
Course Instructor: Sierra Dawson PhD, ATC
Office: 131 Esslinger Hall
*See course office hours schedule on Blackboard for dates/times in the Science Library for
office hours.
Phone: 541. 346.1487
E-mail: sdawson@uoregon.edu
Notes: I work on email once a day (Monday-Friday), so expect at least 24-48
hours for a response. For the quickest response, post your questions to the
course discussion board on Blackboard, if they are not personal in nature. If
you need a quiz reset, please contact your lab instructor for the quickest
response.
Course grader, Lab Preparator & Facilitator & TA coordinator:
Austin Hocker
ahocker@uoregon.edu
Lab Instructors:
Austin Hocker
Brett Ely
Dylan Sieck
Mark Bogost
Matt Ely
Michael Francisco
Zach Clayton
ahocker@uoregon.edu
bely@uoregon.edu
sieck@uoregon.edu
mbogost@uoregon.edu
mely@uoregon.edu
mfrancis@uoregon.edu
zclayton@uoregon.edu
Pre-requisites: BI 212 is required with a C or better, in addition to HPHY 321 as a
pre or co-requisite. We believe the strongest learning experiences occur when
students select to take HPHY 321 & HPHY 322 simultaneously, as these two
classes have been designed to compliment each other.
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Required Resources:
1. Guyton & Hall’s Medical Physiology 12th Edition (or older). This is a
sophisticated resource that will serve you both now and in the future, should
you pursue study in the health care profession, or in research. The text is
required, and is available in both print version (with includes online access &
search features), as well as a mobile app from Inkling (which I personally love!).
2. iclicker 1 or 2. We will use personal response systems (or clickers) in class each
day to provide you with a chance to challenge your knowledge using old exam
questions. Please purchase your iclicker at the bookstore and bring it to class
every day (starting the second day of class).
3. Anatomy & Physiology Revealed 3.0, Web-Based Program. This is a great
piece of software that we believe you will use extensively. Students will need
access to this software to complete some of the assignments this term.
4. Computer access and software (if applicable): You will need regular access to a
computer, the Internet, MS Office programs (Word and Excel), and the free
Adobe Reader for this course.
5. One packet of 3x5 index cards for use in the large class and lab setting.
Course Overview: The focus of this course will be the nervous system, muscle
physiology, and special senses. Discussions will include ion movement, action
potentials, synapses & receptors, the central, peripheral and autonomic nervous
systems, excitation-contraction coupling in skeletal muscle and the mechanisms
specific to vision, hearing, smell & taste, in addition to the somatosensory
system. Information will be uncovered as you create your own unique book
called your “External Brain”, which you will use both in class and during
examinations as you apply your knowledge to novel clinical scenarios.
Complementary laboratory experiences will provide the opportunity to collect
data on yourself and lab-mates using the PowerLab system. Our goal is for you
to become deeply knowledgeable about human physiology, and be able to apply
the information you have compiled to clinical or research situations.
Course Philosophy: It is our intention to provide the best environment to
facilitate active learning. You will be encouraged to discuss, challenge, and
critique information by interacting with instructor, peer tutors, and fellow
students. You will be challenged to “own” the knowledge of physiology and
apply it to unique situations. We also believe that a great laboratory experience
can make learning about a topic more engaging, meaningful and successful.
Great laboratories include small group experiences in which you can practice
what you are learning, and “do” physiology as the experts would. It is a place
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that hands-on, practical and visual learners can make lecture content tangible
and concrete. It is a place that creative and original ideas can be explored, while
oral and written communication skills can be enhanced. Your lecture & lab
instructors will provide a positive environment for diverse learners to achieve
their goals, and will encourage your regular participation.
Course Expectations: You can expect to spend 15 hours per week working on
this 5-credit course (approximately 5 hours in lecture/lab, and 10 hours creating
your External Brain, completing pre-lab assignments, writing lab reports, taking
weekly quizzes and studying for exams).
You can expect your instructors to work hard to facilitate your learning, be
available to help you outside of class, and be dedicated to your success.
You are expected to be present for every lecture/lab experience, to have class
preparations and assignments completed, to check Blackboard Announcements
and Discussion Board regularly, and to actively participate in discussions and
activities.
Together, we can create a successful and enjoyable learning environment that
will prepare you for future learning in the pre-health sciences.
Overarching Course Learning Outcomes:
a. Students will be able to connect the foundational knowledge from coursework
and life experience collected to date to their understanding of physiology. Given
External Brain Chapters and External Brain Guidelines you will be able to create
specific content in the form of illustrations, charts, or narrative using textbook,
Internet, or CD-ROM sources, in a way that most suits your learning or
information- retrieval style.
b. You will be able to correctly recall information you have created both in your
External Brain, during class & lab discussions, and from lab experiments, when
given closed-book multiple-choice/true-false or short answer examinations.
c. Specifically, you will also be able to correctly recall the concepts from the
following content areas during closed-book multiple-choice/true-false or shortanswer examinations:
1. You will be able to describe the way cells communicate, including ion
movement, action potentials and the second messenger system.
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2. You will understand the basic functions of the major areas of the brain
as well as the spinal cord and spinal nerves.
3. You will be able to discuss the function of cranial nerves and the
pathophysiology related to damage of specific cranial nerves.
4. You will be able to predict how the autonomic nervous system will
affect the body’s organs relative to homeostasis, “fight or flight”, as well
as “rest and digest” based on the neurotransmitters or receptors under
discussion.
5. You will be able to describe the structure and function of muscle as it
relates to histology, the sliding filament theory, fiber type, and sarcomere
length.
6. You will understand the physiology that underlies the ability to see,
hear, taste and smell.
d. During open book multiple choice/true-false examination (while referencing
the information constructed in your External Brain) you will be able to use the
currently understood principles of physiological systems to critique claims or
decide if an explanation is plausible or not, and you will be able to develop
plausible explanations for clinical observations based on your understanding of
physiology principles.
e. You will be able to discuss your knowledge and application of physiology
with your peers and be able to judge the accuracy of your original exam
responses based on this discussion. You will then be able to select which answers
from your individual examination to change, and which to keep the same during
your group examination.
f. You will be able to perform a hypothesis driven experiment, present the data
graphically, use the results to support or refute the hypothesis and incorporate
results in your understanding of physiology, all while using appropriate
scientific language & formatting etiquette. You will be able to find current or
highly cited relevant scientific literature from reputable scientific sources that
supports your topic and cite it correctly so that others can easily find it in the
works cited section of your report.
g. You will be able to apply the knowledge you have gathered during lecture/lab
discussions and lab experiments to answer multiple choice questions during online timed quizzes each week, as a low-stakes method to assess your
understanding of the materials.
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h. You will be able to design and carry out simple laboratory experiments to
answer scientific questions of your choosing.
i. You will be able to conduct yourself in a professional manner, including
professional communication, lab etiquette, timeliness of work produced,
preparation and engagement, as well as respect for lab equipment and tidiness of
lab workspace.
Grading:
External Brain:
Lecture exams:
Lab Reports:
Professionalism:
Quizzes:
10%
70% (Midterm 1= 15%, Midterm 2 = 25% and final exam = 30%)
20%
see deductions
see deductions
Possible deductions from total grade:
Pre-lab assignments
-2% each time, beyond the first, pre-lab is not 80%
correct ½ hour prior to lab time.
Lab attendance
-2% each time, beyond the first, absent from lab.
Quizzes
-2% for more than one quiz not 80% correct by due
date.
Professionalism
Points deducted from week 11 professionalism rubric
are deducted from final percentage grade.
EB check-off
Final EB score earned (out of 10) will be changed to 0
if EB is not checked off in week 10.
Grades: Not assigned on a curve, so you are NOT in competition with your
fellow students. Plus and minus grades (ie: A+, B-) will be assigned in the
following way: 80-82% = B-, 83-86% = B, 87-89 = B+….etc.
Additional notes regarding learning experiences:
*Pre-lab assignments: Preparation for lab each week via completion of the
Blackboard pre-lab assignment is expected. This is not a quiz. You are welcome
to talk to other students in the class, and use your lab materials, while
completing the pre-lab assignment. You may re-take the pre-lab as many times as
you like. If the pre-lab is not 80% correct and submitted a half-hour (30 minutes)
prior to your lab time more than once 2% will be deducted from your final
course grade.
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*Attendance/participation: If you are absent from the lab (or non-participatory)
more than once, 2% will be deducted from your final course grade. You will still
need to acquire the data from your lab mates to complete your lab report if you
are absent.
*Quizzes: Available on Blackboard every week (see schedule on final page of
syllabus) from Thursday afternoon until Saturday midnight and will include 8-10
questions from that week’s physiology concepts (lab, lectures and EB
assignments). This is a purely formative assessment, so you can retake the quiz
as many times as you like. To avoid deductions, please submit your quiz with at
least 80% correct by the due date. You may re-take the quiz as many times as you
like during that timeframe. A maximum of 2% will be deducted from your final
course grade if more than one quiz does not meet these criteria.
*Professionalism: We believe that developing your skill as a professional is
extremely important for your future success. You will receive feedback regarding
your professionalism formally twice during the term (week 6 and week 11) using
the Professionalism Rubric. The feedback week 6 is purely formative, meaning
it is just for you to learn from, while the feedback week 11 will be summative.
Any points deducted from the week 11 Professionalism Rubric will also be
deducted from your course percentage grade.
*Lab Reports: Each student must write their own original lab report, and create
their own original figure/graph. Due prior to the next lab meeting (submitted
via blackboard). Each day a lab report is late, 10 points will be deducted from the
score. Timeliness is not only an important professional behavior, but also
facilitates an appropriate turn-around time by the grader. Please put your best
effort into your lab reports. Lab instructors may ask you to resubmit a lab report
if they do not feel it represents an honest effort. If this is the case, a minimum of
10 points will be deducted, plus 10 points for every subsequent day until resubmitted.
External Brain (EB) Homework Assignments: To prepare for class discussions, a
portion of your External Brain will be due electronically every day ½ hour prior
to the start of class on the designated Blackboard site. Students are expected to
upload their EB as a .pdf file, and to double check it was uploaded correctly. At
the end of the term, the lowest EB grade will be dropped (which might be a
grade of zero from not turning an assignment in, or just the lowest scoring EB).
In order for your External Brain score to be applied to your course grade, you
must hand in your EB during lab at two different times (weeks 5 & 10) organized
like a book, chapter by chapter, in a 3-ringed binder. Failure to submit your
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complete EB at either of these times will reduce the final EB value to 5% of the
course grade if the week 5 check-off is missed, or to 0% if the week 10 check-off is
missed.
Discussion Groups: During each class period there will be group activities or
clicker questions that are designed to challenge your knowledge. All students
will break into groups of 3 in their lab sections, and these same groups should
work together during our class period. You will be expected to sit with your
group during class to facilitate smooth transitions into group activities.
Throughout the term, there will be opportunities for your group to complete a
portion of each exam together.
Details of Course Examinations:
Part 1 of the exam will take place during class and will involve a closed-book
portion, and an open-book portion. The closed-book portion will include short
straightforward questions (multiple choice/true-false and short answer). The
open-book portion will include application of human physiology to clinical or
research situations. Students are welcome to use class notes/PowerPoint slides
and their External Brain while answering the comprehensive unique, clinical,
open-book questions. Part 1 of the exam is worth 80% of the exam score.
Part 2 of the exam is take-home/group exam worth 20% of the combined exam
score. You may use any resources you wish (internet, texts, group members,
friends, family etc.) to research the answers to the same exam questions
answered during part 1. This portion of the exam is not optional, and answers
must be uploaded to Blackboard by the due date, as the exam key will be
available immediately following the due date/time.
Part 3 of the exam IS optional and should only be exercised by a select number of
students in the class who chose a different answer than the answer key due to the
existence of an “alternate meaning” for the words in the question, or have a
published resource which clearly supports their answer. It would not be
appropriate to submit Part 3 of the exam if the question was misread (ie: read the
word “true”, instead of “false”), or if another authority says your answer is
correct, but you lack a published resource to back up your answer. Part 3 of the
exam must follow an essay/paragraph format and include the checklist that is
available on blackboard in the Housekeeping folder. If your argument has merit,
you will redeem the lost points for that question and your Part 1 exam grade will
be changed to reflect this. Be sure to check the cover page of the exam for the due
date for Part 3 of that particular exam.
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Each student’s exam score contribution of 70% of the course grade will be
calculated as outlined below, and the highest total will be used when
determining the final course grade. The expectation is that students participate in
all 3 exams. The cumulative final exam must be completed, as scheduled, in
order to pass the course and receive a letter grade. If academic misconduct
occurs, leading to a grade of zero on a specific exam, the grading options will be
modified to ensure the exam in question is included in the final grade
calculation.
Lecture Exam Grading Options:
option A
Exam 1
15
Exam 2
25
Final Exam
30
Total exam grade 70%
option B
0
30
40
70%
option C
20
0
50
70%
option D
0
0
70
70%
Accessibility: Although this course has been designed using the principles of
Universal Design, I invite you to talk with me if some aspect of the course is not
accessible to you, and requires adaptation. I would be happy to consider changes
that would make your learning experience more positive. You are also
encouraged to contact the Accessible Education Center (AEC) in 164 Oregon Hall
at 346-1155 or uoaec@uoregon.edu. Students with a letter from AEC indicating
additional time be provided on exams are encouraged to take their exams at the
testing center aectesting@uoregon.edu.
Plagiarism & Cheating: Plagiarism, as defined below, is obviously not
permitted. If plagiarism or cheating is suspected, the office of student conduct
will be contacted, and the outcome could include an F in the class. Please read
the following quotation, from the Office of Student Life's Academic Dishonesty
Policy.
“Academic Misconduct: The University Student Conduct Code (available at
conduct.uoregon.edu) defines academic misconduct. Students are prohibited
from committing or attempting to commit any act that constitutes academic
misconduct. By way of example, students should not give or receive (or attempt
to give or receive) unauthorized help on assignments or examinations without
express permission from the instructor. Students should properly acknowledge
and document all sources of information (e.g. quotations, paraphrases, ideas)
and use only the sources and resources authorized by the instructor. If there is
any question about whether an act constitutes academic misconduct, it is the
students’ obligation to clarify the question with the instructor before committing
or attempting to commit the act.”
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Downloaded January 3, 2014 from:
http://uodos.uoregon.edu/StudentConductandCommunityStandards/Academi
cMisconduct/AddressingAcademicMisconduct/tabid/249/Default.aspx.
As a reminder, when completing External Brain assignments or Lab Reports,
be aware that re-wording the ideas of others can lead to a charge of plagiarism.
Please do not work with your groups or collaborate when writing External
Brain assignments or Lab Reports.
The Final Word:
You will find that your course instructors work hard to support your learning,
and provide multiple opportunities for you to be successful. At the end of the
term, when your grade has been calculated, please do not request any
opportunities for extra credit, or your grade to be bumped up to the next grade
level. No such request will be granted.
Weekly Outline (including exam dates – see next page)
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Week
Topic overview
Week 1:1 General Course Intro
Week 1
Week 1:2. Membrane Potential
Week 2:1 Action Potentials
Week 2
Week 2:2 Graded potentials, Spatial Summation
Week 3:1 Synapse
Week 3
Week 3:2 G Protein Coupled Receptors
Week 4:1 Skeletal muscle: excitation-contraction
coupling.
Week 4
Week 4:2 Skeletal muscle: motor units &
mechanics.
Week 5:1 Finish muscle & review for exam
Week 5
Week 5:2 Midterm 1
Part 1 – in class Thurs. Oct 30th
Part 2 – due Sat. Nov 1st at NOON.
Part 3 – (optional) due Tues. Nov.4th at NOON via
email to Sierra.
Week 6:1 Reflexes
Week 6
Week 6:2 Sensory Neurons
Week 7:1 Autonomic nervous system
Week 7
Week 7:2 Autonomic nervous system
Week 8:1 Clinical correlates: neurophysiology
Week 8
Week 8:2 Special senses – vision
Lab activities
Course Overview: course
philosophy and policies,
syllabus, and lab
information.
Introduction to scientific
method
Due: Week 1 Quiz
Lab 1: Nerve Conduction
Velocity
Due: Week 2 Pre-Lab
Due: Week 2 Quiz
Lab 2: Stimulus Response
Relationship (Action
Potentials)
Due: Week 3 Pre-Lab
Due: Report for Week 2 lab
Due: Week 3 Quiz
Lab 3: Skeletal Muscle
Contractile properties
Due: Week 4 Pre-Lab
Due: Report for Week 3 lab
Due: Week 4 Quiz
Lab 4: Prolonged Muscle
Contraction and Fatigue
Due: Week 5 Pre-Lab
Due: Report for Week 4 lab
Due: EB-Book check-off during
Lab
* No quiz*
Lab 5: Patellar tendon reflex
& reaction time to visual,
auditory & tactile
stimulation
Due: Week 6 Pre-Lab
Due: Report for Week 5 lab
Due: Week 6 Quiz
Lab 6: Autonomic Nervous
System
Due: Week 7 Pre-Lab
Due: Report for Week 6 lab
Due: Week 7 Quiz
Lab 7: Build-your-ownexperiment
Due: Week 8 Pre-Lab
Due: Report for Week 7 lab
Due: Week 8 Quiz
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Week 9
Week 9:1 Midterm 2
Part 1 – Tues. Nov. 25th
Part 2 – due Fri Nov. 28th at NOON
Part 3 – (optional) due Sunday Nov. 30th at NOON
via email to Sierra
Week 9: No Lab
(Thanksgiving week)
Week 9:2 no class due to Thanksgiving
Week 10:1 Special senses – hearing
Week 10
Week 10:2 Special senses –smell & taste
Finals
Lab 8: Special Senses
Due: Week 10 Pre-Lab
Due: Report for Week 8 lab
Due: Week 10 Quiz
* EB-Book check-off during
Lab
Exam:
Part 1:Wednesday December 10th 8:00am
Part 2: Due Thursday December 11th at NOON.
Part 3: (Optional) due Friday December 12th at
NOON via email to Sierra.
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