Chapter 16 - The Digestive System 1 2 Introduction ● Digestive system consists of the muscular digestive tract and various accessory organs ● Functions include: ingestion, mechanical processing, secretion, absorption, and excretion ● Tract includes the oral cavity, pharynx, esophagus, stomach, small intestine, large intestine, rectum, and anus 3 Composition of The Digestive System ● Epithelium and underlying connective tissue ● Lamina propria, form the mucosa (mucous membrane) of the digestive tract ● Submucosa, the muscularis externa, and the adventitia ● Serosa, a serous membrane ● Mesenteries suspend portions of the digestive tract ● Neurons that innervate the smooth muscle involuntary 4 Movement ● Muscularis externa propels materials through the esophagus by means of the contractions of peristalsis ● Segmentation movements in areas of the small intestine churn digestive materials Peristalsis Segmentation 5 Oral Cavity ● Functions of the oral cavity: ○ 1) sensory analysis of potential foods ○ 2) mechanical processing using the teeth, tongue, and palatal surfaces ○ 3) lubrication of food by mixing with mucus and salivary secretions ○ 4) digestion by salivary enzymes 6 Oral Cavity ● Also called the buccal cavity, is lined by oral mucosa ● Hard palate and soft palate form its roof ● Tongue forms the floor 7 Tongue ● Primary functions of the tongue: ○ 1) mechanical processing ○ 2) manipulation to assist in chewing and swallowing ○ 3) sensory analysis 8 Glands ● Parotid, sublingual, and submandibular salivary glands discharge their secretions into the oral cavity ● Saliva lubricates the mouth, dissolves chemicals, flushes the oral surfaces, and helps control bacteria ● Salivation is usually controlled by the ANS 9 Chewing ● Mastication (chewing) occurs through the contact of the opposing surfaces of the teeth ● The periodontal ligament anchors each tooth in a bony socket ● Dentin forms the basic structure of the tooth ● Crown is coated with the enamel ● Root is covered with cementum ● The 20 primary teeth, or deciduous teeth, are replaced by the 32 teeth of the secondary dentition during development 10 Passageway Between the Oral Cavity and Esophagus ● Pharynx serves as a common passageway for solid food, liquids, and air ● Pharyngeal muscle contractions propel food mass ● Esophagus carries solids and liquids from the pharynx to the stomach 12 Swallowing ● Deglutition (swallowing) can be divided into oral, pharyngeal, and esophageal phases ● Begins with the compaction of a bolus and its movement into the pharynx ● Epiglottis covers the larynx as the bolus moves into the esophagus ● After opening of the upper esophageal sphincter, peristalsis moves the bolus down the esophagus to the lower esophageal 13 sphincter Stomach ● Four major functions: ○ 1) temporary storage of ingested food ○ 2) mechanical breakdown of food ○ 3) breakage of chemical bonds by acids and enzymes ○ 4) production of intrinsic factor (absorbs vitamin B12) ● Chyme forms in the stomach as gastric and salivary secretions are mixed with food 15 Stomach ● Four regions of the stomach: cardia, fundus, body, and pylorus ● Pyloric sphincter guards the exit out of the stomach ● In a relaxed state the stomach lining contains numerous rugae 16 ● Within the gastric glands, parietal cells secrete intrinsic factor and hydrochloric acid ● Chief cells secrete pepsinogen, which acids in the gastric lumen convert to the enzyme pepsin ● Gastric gland endocrine cells secrete the hormone gastrin Stomach 17 Stomach ● Gastric secretion includes ○ (1) the cephalic phase, which prepares the stomach to receive ingested materials; ○ (2) the gastric phase, which begins with the arrival of food in the stomach ○ (3) the intestinal phase, which controls the rate of gastric emptying 18 Small Intestine ● Includes the duodenum, the jejunum, and the ileum ● The ileocecal valve, a sphincter, marks the junction between the small and large intestines ● Intestinal mucosa bears transverse folds called plicae circularis and small projections called intestinal villi ● Both structures increase surface area for absorption ● Each villus contains a lymphatic 20 capillary called a lacteal Small Intestine Digests and Absorbs Nutrients ● Some of the smooth muscle cells in the muscularis externa of the small intestine contract periodically, without stimulation ● Brief, localized peristaltic contractions that slowly move materials along the tract ● Intestinal glands secrete intestinal juice, mucus, and hormones ● Intestinal juice moistens chyme, helps buffer acids, and dissolves digestive enzymes and the products of digestion ● Most of the important digestive and absorptive functions occur in the small intestine 22 Pancreas and Gallbladder ● Pancreatic duct penetrates the wall of the duodenum, where it delivers the secretions of the pancreas ● Pancreas has both an endocrine function (secreting insulin and glucagon) and an exocrine function (secreting water, ions, and digestive enzymes into the small intestine) ● Pancreatic enzymes include carbohydrases, lipases, nucleases, and proteases 24 ● Produce pancreatic juice Liver ● Liver is the largest visceral organ in the body and performs over 200 known functions ● Made up of four unequally sized lobes: the left, right, caudate, and quadratic lobes ● Blood is supplied to the lobules by branches of the hepatic artery and hepatic portal vein ● Major functions include: 1) metabolic regulation, 2) hematological regulation, and the 3) production of bile ● Gallbladder stores and concentrates bile for release into the duodenum 26 Large Intestine ● Functions are to 1) reabsorb water and compact feces, 2) absorb vitamins made by bacteria, and 3) store fecal material prior to defecation ● Has three parts: the cecum, colon, and rectum ● Cecum - collects and stores material from the ileum and begins the process of compaction; appendix is attached ● Colon - has a larger diameter and a thinner wall ● It bears haustra (pouches) and taeniae coli (longitudinal bands of muscle) 28 Large Intestine ● Large intestine reabsorbs water and other substances, such as vitamins, bile salts, organic wastes, and toxins ● Bacteria residing in the large intestine are responsible for intestinal gas, or flatus ● Distension of the stomach and duodenum stimulates peristalsis, or mass movements, of feces from the colon into the rectum ● Muscular sphincters control the passage of fecal material to the anus ● Distension of the rectal wall triggers 29 the defecation reflex References ● Whats Up Dude. (2020, April 23,). Digestive System [Video]. Youtube. https://www.youtube.com/channel/UCG7WdmLGzacESLc9DMyZb-A