ABNORMALITIES OF TOOTH NUMBER WITH CLINICAL IMPORTANCE. Oluwatosin Ajibade DEN/2014/010 OUTLINE • Introduction • Epidemiology • Abnormalities of teeth number: • Supernumerary Teeth • Anodontia • Double Teeth • Conclusion • References INTRODUCTION Tooth development and eruption involves various complex processes. At any time during any of these stages of development or eruption, there may be insult leading to abnormalities in the tooth shape, structure, number and size. Epidemiology Of Dental Abnormalities • The study of prevalence pattern and clinical presentation of developmental dental hard-tissue anomalies in children with primary and mixed dentition was done in Ile-Ife in 2014 by Dada Oluwaseyi Temilola et al showed that; • two hundred and seventy six (26.6%) children had dental anomalies. Of these, • 23.8% had one anomaly, • 2.5% had two anomalies, • and 0.3% had more than two anomalies. • , 49.3% male, • 50.7% female, • and 47.8%, 28.6% and 23.6% were children from low, middle and high socioeconomic classes, respectively. Abnormalities Of Tooth Number • The expected number of teeth in the primary dentition is 20 while 32 is expected in permanent dentition, when there is a deviation from these that is not physiological(exfoliation and eruption in primary dentition)it is referred to as abnormalities of teeth number. • Anomalies in teeth number are caused by disruption in the dental lamina formation stage of dental development. • Anomalies in the number of teeth can occur in both primary and permanent dentition. ABNORMALITIES OF TOOTH NUMBER •The abnormalities of tooth number includes the following: •Supernumerary teeth •Anodontia •Double teeth Supernumerary Teeth • Also known as hyperdontia or extra teeth. • These are odontogenic structures formed from tooth germ in excess of the usual number for any given region of the dental arch. • Results from hyperactivity of dental lamina and can occur as a part of a syndrome, specially cleft lip and palate, cleidocranial dysostosis and Gardner’s syndrome. It is inherited as an autosomal dominant or X-linked trait which explains the sex dominance. • They may be single or multiple and unilateral or bilateral in distribution and can occur in any region of the dental arch. Supernumerary Teeth • Extra teeth (supernumerary teeth) have been reported to occur in 0.2-0.8% of Caucasians in the primary dentition and 1.5-3% in the permanent dentition in the same populations. There is a male to female ratio of approximately 2 : 1. Patients with supernumerary primary teeth have a 30-50% chance of these being followed by supernumerary permanent teeth. Supernumerary Teeth • Supernumerary teeth occur most frequently in the premaxilla in the midline(mesioden), or immediately adjacent to the midline and are less common in the primary dentition than in the permanent dentition . • In the primary dentition, the supernumerary teeth are usually normal or conical in shape while in the permanent dentition they have a great variety of shapes which may be classified as : Supernumerary Teeth • Conical – small, peg-shaped crown • Tuberculate – short, barrel shaped crown • Supplemental – resembles the normal teeth (incisiform, caniform, molariform) • Odontome – varied shape, manifest due to disorders of differentiation and are of two types; compound odontome and complex odontome. • The majority of supernumerary teeth are either conical or tuberculate. Supernumerary Teeth • They can also be classified based on location. • These include: Mesiodens Paramolars Parapremolars Distomolars Mesioden • Most common supernumerary tooth • Tooth situated between maxillary central incisor • They are often conical in shape Parapremolars • Extra teeth around premolars, also known as peridens • May be located buccal or palatal to the premolar Paramolars • These are extra teeth around the molars • May be located palatally or buccally Distomolars • Supernumerary teeth distal to the 3rd molar. • Also referred to as distodens Clinical Significance Of Supernumerary Teeth The supernumerary teeth could result in the following: • May interfere with the emergence of the adjacent tooth into the oral cavity • Crowding • Displacement of the adjacent tooth • Root resorption of adjacent tooth • Cyst formation • Diastemas Treatment It depends on the type and the position of the supernumerary teeth. • If the tooth is not interfering with the eruption of the teeth nor causing displacement of erupted teeth, may be allowed to remain. Periodic examination is however essential to see if any undesirable changes occur. • If the tooth is interfering with eruption or displacement of erupted teeth, extraction is required. It should be noted that time is of importance in the management of supernumerary teeth. Early diagnosis and prompt treatment is necessary for prevention of deleterious effects on dentoalveolar structures. Anodontia It is also called anodontia vera. It is a rare genetic disorder • characterized by congenital absence of all primary or permanent teeth. . Anodontia There are different types which include: • Complete anodontia/total anodontia: This is when all teeth are missing • Partial anodontia/hypodontia: This is when one or several teeth are missing. • Pseudoanodontia: This is when teeth are absent clinically because of impaction or delayed eruption • False anodontia: This is when teeth have been exfoliated or extracted. • Oligodontia is a term used to describe a situation where multiple usually more than six teeth are missing Anodontia • The cause of an isolated missing tooth is often unclear; this may be genetic in origin or associated with some environmental insult during development. Missing teeth have been reported in association with multiple births, low birth weight, and increased maternal age. Rubella and thalidomide embryopathies may also be associated with missing teeth Anodontia • Autosomal dominant inheritance of missing teeth is seen in families with mutations in the MSX1 gene on chromosome 4. Missing third molars and second premolars are the most common finding. These families may also have clefting segregating with the missing teeth. Mutations in the MSX1 gene are also seen in the tooth-nail (Witkop) syndrome. • A pattern of autosomally dominant inheritance of missing teeth, particularly molars, is seen as a result of mutations in the PAX9 gene on chromosome 14. Clinical Significance • If it is in the anterior, it can be unaesthetic • Patients are prone to gingivitis and caries due to food packing in the space of the missing teeth. • There may be drifting of the tooth adjacent or opposite to the space Treatment • The care of children with multiple missing teeth can be complex and ideally requires multidisciplinary input from pediatric dentists, orthodontists, and prosthodontists as well as genetic counselling. • In cases of anodontia, full dentures are required. These can be provided, albeit with likely limited success, from about 3 years of age, with the possibility of implant support for prostheses provided in adulthood. • Multiple missing teeth can be treated by the use of partial dentures, with implants as part of the treatment protocol at a later age. Double Teeth (Connation) • These teeth are joined together and are often described by terms that are based on the aetiology of the anomaly. • For instance, fusion is used to describe the union between the enamel and the dentine of 2 or more normally separate developing tooth germs. • While gemination is the term used to describe the partial development of two teeth from a single tooth bud following incomplete division. Double Teeth • However it can be difficult to distinguish between fusion and gemination on clinical grounds. • The term connation is preferred because it describes its appearance without suggesting the aetiology. • Connated teeth are more frequent in the primary dentition, and in the incisor or canine region. Fusion Gemination Clinical Significance • Arch Assymetry • Spacing • Poor aesthetics • May impede the eruption of adjacent tooth Treatment • In the permanent dentition, surgical separation of fused teeth may be possible with subsequent orthodontic alignment and restorative treatment as needed to reshape the crown. • Take a radiograph to check if there are separate pulps or not. • Reshaping of geminated tooth may be impossible and extraction may be the only alternative, orthodontic therapy and/or prosthetic replacement is then required • The groove on a double tooth is extremely prone to caries, thus fissure sealing is essential Conclusion It is important that we understand the concept of tooth number abnormalities to be able to accurately diagnose and treat complications that arise from them. References • A manual of paediatric dentistry • CAMERON paediatric dentistry • PAEDIATRIC DENTISTRY - 3rd Ed. (2005) OF TOOTH DEVELOPMENT AND ERUPTION BY ADEYEMO TOMILOLA • ABNORMALITIES AYO • https://europepmc.org/article/MED/31636863 • https://pubmed.ncbi.nlm.nih.gov/25323952/