18PHFCO
NANOTECHNOLOGY
PRESENTED BY:
MATHESHWARA R
20D053
NANOMECHANICS
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TABLE OF
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INTRODUCTION
NANOMECHANICS IN
DIFFERENT FIELDS
THE NANOMECHANICS OF
INDIVIDUAL PROTEINS
MONITORING THE
EFFECTIVENESS OF THE
DRUG ON CANCER CELLS
NANOMECHANICS OF SHAPE
MEMORY ALLOYS
FUTURE DEVELOPMENTS OF
NANOMECHANICS
REFERENCES
NANOMECHANICS
❑ Nanomechanics focuses on the basic mechanical features of
nanoscale physical systems.
❑ Solid-state physics, quantum mechanics, statistics, classical
mechanics, and materials science all come together in
nanomechanics.
❑ Nanomechanics focuses on physical systems study and usage
through fundamental mechanical characteristics at the
nanoscale, such as elastic, kinetic, and thermal.
NANOMECHANICS IN DIFFERENT FIELDS
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The mechanics and kinetics of biological species have been studied using
nanomechanical characterization techniques, including atomic force microscopy,
nanoindentation, nanotribology, optical tweezers, and other hybrid approaches.
Nanomechanical characterization techniques and their prospective applications in
healthcare research have been studied intensely in recent years. The use of
nanomechanical cantilevers to detect cancer and myocardial infarction without the
need for labels has been addressed in detail.
In regenerative medicine, nanomechanics plays an important role in the selection
and design of biocompatible scaffolds for tissue regeneration.
Nanomechanics is a subfield of nanotechnology that focuses on the mechanical
characteristics of constructed nanostructures and nanosystems instead of the
theoretical aspects of nanotechnology.
THE NANOMECHANICS OF
INDIVIDUAL PROTEINS
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Motility, differentiation, and muscular contraction are some functions
regulated by mechanical forces. Individual constitutive proteins must be able
to stretch and repeatedly recoil over an extended period to respond to
dynamic changes in mechanical stress.
Protein folding biochemistry studies done in bulk cannot access the
molecular processes driving mechanical unfolding and refolding of proteins
because they often cannot apply stresses to individual proteins.
When paired with a custom protein engineering strategy that uses singlemolecule nanomechanical monitoring of protein conformational dynamics,
this technology has allowed for unparalleled length, time, and force
resolutions to be achieved
MONITORING THE EFFECTIVENESS OF
THE DRUG ON CANCER CELLS
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Nano- and sub- nanometer resolution surface topography imaging
is a primary application of atomic force microscopy (AFM).
This method has been widely used to investigate the
nanomechanical characteristics of healthy and pathologically
changed cells and tissues, and the elastic properties were
measured by Young's modulus.
Nanomechanical characteristics of live cells can be measured
using atomic force microscopy (AFM), a technology with a high
spatial resolution. As a result, AFM may be used to monitor
changes in the cytoskeleton's rearrangement in live cells.
An abnormality in actin filaments and microtubules can lead to
cell death because of their structural and functional abnormalities.
This is why anticancer treatment is focused on cytoskeletal
components.
Monitoring the
Effectiveness of Drugs
Targeting the Cancer Cell
Cytoskeleton by AFM
NANOMECHANICS OF SHAPE
MEMORY ALLOYS
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One of the most important classes of metallic functional materials is the
shape memory alloys which undergoes a reversible martensitic
transformation.
Shape memory alloys, developed during the last two decades, have
enabled significant advancements in multiple fields like microelectronics,
biomedical devices, and energy conversions.
At the nanoscale of the properties and mechanical characteristics of shape
memory alloys are becoming increasingly important as the application sizes
of these devices shrink.
Shape memory alloy nanomechanics based on Nickel, Titanium and Copper
has recently made significant advances in understanding the deformation
processes and different effects of size, and functional fatigue of miniature
samples in polycrystalline forms and also in single-crystalline form.
FUTURE DEVELOPMENTS OF
NANOMECHANICS
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Nanomechanics has vast scope in many fields. There are many more
fields in which further developments have been occurring using
nanomechanics at the nanoscale.
Numerous other fields such as information technology and civil
engineering have also found uses for nanotechnology. These include
producing nanoscale additives used to enhance oil well cementation
and drilling mud to increase extraction rates and the use of
nanocatalyst in the petroleum industry.
REFERENCES
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https://en.wikipedia.org/wiki/
Nanomechanics
https://www.azonano.com/article.
aspx?ArticleID=6017
https://www.sciencedirect.com/topics/
materials-science/nanomechanics
THANK YOU
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