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Летняя сессия 3 курс Лечебное дело Фармакология…

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Летняя сессия
Личный ĸабинет / Курсы / Фаĸультеты
/ БАЗА ЗНАНИЙ / Летняя_сессия
/ ЛЕЧЕБНОЕ ДЕЛО
/ 3 ĸурс Лечебное дело "Фармаĸология" на
английсĸом
3 ĸурс Лечебное дело "Фармаĸология"
на английсĸом
The term "Pharmacokinetics" includes all
В
001
О
А
Interaction of drugs with specific receptors
О
Б
Absorption of drugs
О
В
Distribution of drugs in the body
О
Г
Deposition of drugs in the body
О
Д
Biotransformation of drugs
О
Е
Elimination of drugs from the body
В
002
О
А
Passive diffusion
О
Б
Filtering
О
В
Pinocytosis
О
Г
Active transport
О
Д
Light diffusion
except:
The main mechanism of absorption of drugs
from the digestive tract:
The penetration of drugs through the
В
003 membranes against the concentration gradient
is carried out by:
О
А
Active transport
О
Б
Filtering
О
В
Passive diffusion
О
Г
Lightweight diffusion
В
004
О
А
Hydrophilic compounds
О
Б
Lipophilic compounds
О
В
Both lipophilic and hydrophilic compounds
When substances are administrated orally by
filtration are absorbed:
Absorption of weak electrolytes from the
В
005 gastrointestinal tract with an increase in the
degree of their ionization:
О
А
Weakens
О
Б
Increases
О
В
Does not change
В
006
О
А
Both lipophilic and hydrophilic compounds
О
Б
Polar hydrophilic compounds only
О
В
Only non-polar lipophilic compounds
Which intramuscularly administered drugs are
well absorbed:
The absorption of substances during
В
007
intramuscular and subcutaneous
administration depends on:
The intensity of blood supply to the tissues at
О
А
О
Б
Degrees of ionization of substances
О
В
Binding to plasma proteins
В
008
О
А
Biotransformation of substances in the liver
О
Б
Lipophilicity of the substance
О
В
Degrees of ionization of substances
О
Г
Binding of substances to plasma proteins
О
Д
Intensity of blood supply to organs and tissues
the injection site
Drug distribution in the body depends on all of
these factors, except:
Which drugs more easily penetrate through
В
009 the blood-brain, blood-ophthalmic and other
barriers from the blood to tissues:
О
А
Non-polar lipophilic compounds
О
Б
Polar hydrophilic compounds
О
В
Ionized molecules of weak electrolytes
В
010
О
А
Prolonged
О
Б
Shortened
О
В
Does not change
В
011
О
А
О
Б
О
В
В
012
О
А
О
Б
In the elderly
О
В
In diseases of the liver
О
Г
In children in the first months of life
О
Д
О
Е
When a significant part of the drug is bound to
plasma proteins, its effect
Liver enzymes act on lipophilic compounds,
because lipophilic substances are:
Easily penetrate through the membranes of
hepatocytes by passive diffusion
They penetrate through the membranes of
hepatocytes by active transport
Specifically interact with hepatocyte receptors
Drug biotransformation rate is reduced in all
cases, except:
When using inducers of microsomal liver
enzymes
When using inhibitors of microsomal liver
enzymes
With a decrease in hepatic blood flow
The bioavailability of the drug when
В
013
administered orally shows how much of the
administered dose:
О
А
Reaches the systemic blood flow
О
Б
О
В
В
014
О
А
Increases
О
Б
Decreases
О
В
Does not change
В
015
О
А
Excretion and biotransformation
О
Б
Biotransformation only
О
В
Excretion only
В
016
О
А
It can not have a resorptive effect
О
Б
It can have both local and resorptive effects
О
В
It can have a direct effect
О
Г
May cause reflex action
В
017
О
А
О
Б
О
В
В
018
О
А
Partial agonists
О
Б
Agonists-antagonists
О
В
Antagonists
В
019
О
А
О
Б
О
В
О
Г
G-protein-mediated effect on enzyme activity
О
Д
Effect on the transcription of DNA
О
Е
В
020
О
А
The value of the maximum effect
О
Б
Minimum effective dose
О
В
В
021
О
А
Idiosyncrasy
О
Б
Hypersensitivity
О
В
Accumulation
О
Г
Sensitization
О
Д
Tolerance
О
Е
Tachyphylaxis
В
0022
О
А
Potentiation
О
Б
Addictive behavior
О
В
Drug dependence
О
Г
Cumulation
В
0023
О
А
О
Б
Absorbed from the intestine into the portal
vein
Reaches the location of action
Renal excretion of weak electrolytes with
increasing ionization:
Drug concentration decreasing in the blood
plasma during its elimination occurs due to:
Topical application of the drug is characterized
by everything except:
Intrinsic activity is defined as the ability of a
substance:
Stimulate the receptors and cause a
pharmacological effect
Bind to specific receptors
Block specific receptors and produce a
pharmacological effect
Substances that have less intrinsic activity
than full agonists are called:
Principles of agonist action are everything
except:
Effect on the phospholipids of the cell
membrane
G-protein-mediated effect on ion channel
permeability
Direct effect on the activity of the effector
enzyme
A direct effect on the permeability of ion
channels
It is possible to judge the effectiveness of a
drug by:
The dose at which the substance causes the
maximum therapeutic effect
A genetically determined atypical reaction to a
drug substance is called:
Repeated administration of drugs can cause all
except:
Physical drug dependence is characterized by
everything except:
Improvement of well-being after rapid drug
withdrawal
Improvement of well-being after administration
of drugs
The development of withdrawal symptoms
О
В
(psychosomatic disorders) upon drug
withdrawal
О
В
Г
The need for gradual withdrawal of the drug in
the treatment of physical dependence
0024 The additive effect is characterized by:
Summing the effects of drugs when co-
О
А
О
Б
О
В
О
Г
В
0025
О
А
Binding of the drug to plasma proteins
О
Б
Drug interactions when co- administered
О
В
О
Г
Slowing administration of drug
О
Д
Cumulation
О
Е
Administration of the drug in toxic doses
В
administered
Excess amounts of drugs effects
Amplification effect upon repeated
administration of the drug
Reducing the effect of drugs while taking
Toxic effects can occur due to all of the
following, except:
Slowing metabolism of the drug-induced state
of the organism and its individual features
0026 Teratogenic effects of drugs can occur:
О
А
In I trimester of pregnancy
О
Б
In II trimester of pregnancy
О
В
In III trimester of pregnancy
В
0027 Mutagenic effect of the drug:
О
А
О
Б
О
В
О
Г
В
Damage to the genetic apparatus, which leads
to changes in the offspring genotype
Adverse effects on the fetus, resulting in
congenital malformations
Adverse effect on the fetus, slowing down its
development
Effects on the fetus leading to tumor
development
0028 M-cholinomimetic:
О
А
Pilocarpine
О
Б
Galantamine
О
В
Neostigmine
О
Г
Cytisine
О
Д
Carbacholine
В
0029 N-cholinomimetic:
О
А
Cytisine
О
Б
Pilocarpine
О
В
Galantamine
О
Г
Neostigmine
О
Д
Carbacholine
В
0030 M-cholinomimetics cause:
А
Miosis and decreased intraocular pressure
О
Б
Miosis and increased intraocular pressure
О
В
Miosis and paralysis of accommodation
О
Г
Mydriasis and accommodation paralysis
В
0031 Effects of M-cholinomimetics:
А
Increased secretion of exocrine glands
О
Б
Improving atrioventricular conduction
О
В
Increased blood pressure
О
Г
Decreased bronchial tone
О
Д
Facilitate neuromuscular transmission
В
0032 M-cholinomimetics increase:
А
Smooth muscle tone of internal organs
О
Б
Blood vessel tone
О
В
Heart rate
О
Г
Skeletal muscle tone
В
0033 Pilocarpine causes all effects except:
А
Dilates the pupil
О
Б
Constricts the pupil
О
В
Causes a spasm of accommodation
О
Г
Reduces intraocular pressure
В
0034 Neostigmine causes:
А
Increasing of skeletal muscle tone
О
Б
Increased in heart rate
О
В
Increased blood pressure
О
Г
О
Д
Inhibition of the exocrine gland’s secretion
О
Е
Mydriasis
В
0035
Decreased motility of smooth muscles of the
gastrointestinal tract
The same effects of M-cholinomimetics and
anticholinesterase agents are all except:
А
Increased skeletal muscle tone
О
Б
Decreased intraocular pressure
О
В
Spasm of accommodation
О
Г
Increased secretion of exocrine glands
О
Д
Decreased heart rate
О
Е
О
Ж
В
Increased tone of smooth muscles of internal
organs
Miosis
0036 Anticholinesterase drugs:
А
Inhibit acetylcholinesterase
О
Б
Reduce the action of acetylcholine
О
В
Suppress the synthesis of acetylcholine
О
Г
Increase the synthesis of acetylcholine
В
0037 M-cholinomimetics are used to reduce:
А
Intraocular pressure
О
Б
Blood pressure
О
В
Heart rate
О
Г
Atrioventricular conduction
О
Д
Smooth muscle tone
В
0038 Indications of Pilocarpine:
А
Glaucoma
О
Б
Bronchial asthma
О
В
Intestinal atony
О
Г
Fundus studies
О
Д
Atony of the bladder
О
Е
Myasthenia gravis
В
0039 N-cholinomimetics are used:
А
To facilitate withdrawal of people from
smoking
О
Б
In bronchospasm
О
В
To increase the secretion of the glands
О
Г
To lower blood pressure
В
0040
Acetylcholinesterase reactivators weaken the
effect of:
А
Organophosphorus compounds
О
Б
Reversible anticholinesterase agents
О
В
M-cholinomimetics
В
0041 In case of poisoning with neostigmine used:
А
M-anticholinergics
О
Б
N-cholinomimetics
О
В
Acetylcholinesterase reactivators
В
0042
Pilocarpine in the treatment of glaucoma
causes:
А
Spasm of accommodation
О
Б
Photophobia
О
В
Decreased secretion of tear fluid
В
0043 M-cholinomimetics:
А
All answers are correct
Cause the effects of activating
О
Б
О
В
О
Г
Used in glaucoma
О
Д
M-cholinergic receptor agonists
В
parasympathetic innervation
Facilitate the outflow of intraocular fluid and
reduce intraocular pressure
0044 Anticholinesterase drugs:
А
All answers are correct
Cause the effects of activating
О
Б
О
В
Facilitate neuromuscular transmission
О
Г
Used for intestinal and bladder atony
О
Д
Used for reducing skeletal muscle tone
О
Е
May cause bronchospasm and bradycardia
О
Ж
Prevent hydrolysis of acetylcholine
В
parasympathetic innervation
0045 Cytisine:
А
All answers are correct
With systemic action, causes the effects of
О
Б
О
В
Reflexively stimulates the respiratory center
О
Г
They are used to facilitate smoking cessation
О
Д
Neuronal type N-cholinergic receptor agonist
В
activating sympathetic innervation
0046 Neostigmine:
А
All answers are correct
О
Б
Poorly penetrates the central nervous system
О
В
Causes miosis
О
Г
It is used for intestinal and bladder atony
О
Д
It is used to reduce skeletal muscle tone
О
Е
Reversibly inhibits acetylcholinesterase
В
0047 Galantamine:
А
All answers are correct
О
Б
Tertiary amine, crosses the blood-brain barrier
О
В
Effective for bowel and bladder atony
О
Г
It is used to reduce skeletal muscle tone
О
Д
Used in the treatment of Alzheimer's disease
О
Е
Reversible anticholinesterase agent
В
0048 Blocks M1-cholinergic receptors predominantly
А
Pirenzepine
О
Б
Tropicamide
О
В
Atropine
О
Г
Scopolamine
О
Д
Ipratropium bromide
В
0049
Short-acting neuromuscular synapse blockers
(5-10 min):
А
Ditilin (suxamethonium)
О
Б
Tropicamide
О
В
Gigronium
О
Г
Pipecuronium
В
0050 Long-acting neuromuscular synapse blocker:
А
Pipecuronium
О
Б
Pentamine (Azamethonium)
О
В
Ditilin (Suxamethonium)
О
Г
Tropicamide
В
0051 Depolarizing neuromuscular synapse blocker:
А
Ditilin (suxamethonium)
О
Б
Gigronium
О
В
Atracurium
О
Г
Pipecuronium
В
0052
О
Effects of M-cholinergic antagonists - all
except:
А
Increased secretion of the lacrimal glands
Б
Increased intraocular pressure
О
В
Paralysis of accommodation
О
Г
Mydriasis
В
0053
M-cholinergic antagonists reduce everything
except:
А
Heart rate
О
Б
Exocrine gland secretion
О
В
Ciliary muscle tone
О
Г
Bladder tone
В
0054 M-cholinergic antagonists cause relaxation of:
А
All answers are correct
О
Б
Ciliary muscle
О
В
Bronchi
О
Г
Circular iris muscle
В
0055 Ganglion blockers cause everything except:
А
Increased intestinal motility
О
Б
Paralysis of accommodation
О
В
Decreased secretion of exocrine glands
О
Г
Decreased tone of blood vessels
О
Д
Mydriasis
В
0056
The central nervous system in therapeutic
doses is depressed by:
А
Scopolamine
О
Б
Tropicamide
О
В
Atracurium
О
Г
Atropine
О
Д
Ipratropium
О
Е
Pirenzepine
В
0057
M-cholinergic antagonists cause mydriasis
because they relax:
А
Circular muscle of the iris
О
Б
Radial muscle of the iris
О
В
Ciliary muscle
In case of poisoning with anticholinesterase
В
0058 agents, atropine eliminates their effects
associated with activation:
А
Neuroeffector parasympathetic synapses
О
Б
Neuromuscular synapses
О
В
Neuroeffective sympathetic synapses
О
Г
Ganglionic synapses
The effects of ganglion blockers due to the
В
0059 blockade of the parasympathetic ganglia are
all except:
А
Dilation of blood vessels
О
Б
Paralysis of accommodation
О
В
Decreased secretion of exocrine glands
О
Г
Mydriasis
О
Д
Decreased intestinal motility and bladder tone
В
0060
А
О
Б
О
В
В
0061
Pentamine (azamethonium) lowers blood
pressure because:
Blocks N-cholinergic receptors in the
sympathetic ganglia
Blocks N-cholinergic receptors in the
parasympathetic ganglia
Depresses the vasomotor center
Effects of M-cholinergic antagonists which
have a pharmacological value, all except:
А
Increased intraocular pressure
О
Б
Mydriasis
О
В
Decreased secretion of exocrine glands
О
Г
Paralysis of accommodation
О
Д
Increased heart rate
О
Е
Improving atrioventricular conduction
О
Ж
В
Decreased tone of smooth muscles of internal
organs
0062 Ipratropium is used for:
А
Broncho-obstructive lung diseases
О
Б
Hypersecretion of gastric glands
О
В
В
Spastic contractions of the abdominal cavity
smooth muscle organs
0063 Pirenzepine is used for:
А
Hypersecretion of gastric glands
О
Б
Broncho-obstructive lung diseases
О
В
В
0064
А
О
Б
Spastic contractions of the abdominal cavity
smooth muscle organs
Tropicamide is used in ophthalmic practice
because:
With a single application, it acts on the
muscles of the eye for a short time
Reduces intraocular pressure
When applied topically selectively blocks m-
О
В
cholinergic receptors of the eye’s smooth
muscles
В
0065 With atropine poisoning occurs all except:
А
Sedation
О
Б
Hallucinations, delusions
О
В
Psychomotor agitation
О
Г
Photophobia
О
Д
Tachycardia
О
Е
Dry mouth
О
Ж
Hyperthermia
В
0066 Ganglion blockers:
А
All answers are correct
Eliminate the effects of parasympathetic
О
Б
О
В
О
Г
О
Д
О
Е
Cause orthostatic hypotension
О
Ж
Used to relieve hypertensive crises
О
З
Block neuronal type N-cholinergic receptors
В
innervation
Eliminate the effects of sympathetic
innervation
Reduce the tone of blood vessels
Reduce the tone of the gastrointestinal tract
smooth muscles
0067 Atropine:
А
All answers are correct
Blocks M-cholinergic receptors of various
О
Б
О
В
О
Г
Easily penetrates the blood-tissue barriers
О
Д
Can cause an acute attack of glaucoma
О
Е
О
Ж
В
subtypes
Indiscriminately blocks the M-cholinergic
receptors of the exocrine glands
Causes symptoms of acute psychosis in toxic
doses
Belladonna alkaloid
0068 a1-Adrenoceptors agonist is:
А
Phenylephrine
О
Б
Galazolin (xylometazoline)
О
В
Norepinephrine (norepinephrine)
О
Г
Dobutamine
О
Д
Salmeterol
В
0069 b1-Adrenoceptors agonist is:
А
Dobutamine
О
Б
Salmeterol
О
В
Fenoterol
О
Г
Salbutamol
О
Д
Phenylephrine
В
0070 b2- adrenoceptors long-acting agonist is:
А
Salmeterol
О
Б
Fenoterol
О
В
Dobutamine
О
Г
Adrenaline (epinephrine)
О
Д
Galazolin (xylometazoline)
О
Е
Salbutamol
В
0071 Sympathomimetic
А
Ephedrine
О
Б
Salbutamol
О
В
Galazolin (xylometazoline)
О
Г
Adrenaline (epinephrine)
О
Д
Phenylephrine
В
0072
А
О
Б
О
В
Sympathomimetic effects are caused
predominantly by stimulation of:
Norepinephrine releasing into the synaptic
cleft
Secretion of adrenaline by adrenal chromaffin
cells
Adrenergic receptors
Epinephrine (adrenaline) effects due to the
В
0073 stimulation of b-adrenergic receptors – are all
except:
А
Mydriasis
О
Б
Increased heart rate
О
В
Increased heart rate
О
Г
Facilitation of atrioventricular conduction
О
Д
Increasing the automatism of Purkinje fibers
О
Е
Bronchodilatation
О
Ж
Increased renin secretion
В
0074 b1-Adrenoceptors agonists cause
А
Increased heart rate
О
Б
Decreased heart rate
О
В
Vasoconstriction
О
Г
Relaxation of bronchial smooth muscle
В
0075
All following drugs reduce the tone of the
bronchi, except:
А
Norepinephrine (norepinephrine)
О
Б
Salbutamol
О
В
Salmeterol
О
Г
Fenoterol
О
Д
Adrenaline (epinephrine)
О
Е
Ephedrine
В
0076
Drugs which increase glucose concentration in
the blood:
А
Adrenaline (epinephrine)
О
Б
Dobutamine
О
В
Phenylephrine
О
Г
Galazolin (xylometazoline)
В
0077
a1-Adrenoceptros agonists, when administered
intravenously, can cause bradycardia because:
Reflexively activates the influence of the vagus
А
nerve on the heart due to increased blood
pressure
О
Б
О
В
В
0078
А
О
Б
О
В
В
0079
Penetrate into the central nervous system and
stimulate the vagus nerve centers
Have a direct inhibitory effect on the
automatism of the sinus node
Intravenous norepinephrine can cause a
decreasing in heart rate because it:
Increases blood pressure and activates the
baroreceptor reflex
Penetrates into the central nervous system
and inhibits the vasomotor center
Has a direct depressing effect on the
automatism of the sinus node
Phenylephrine is used for all indications,
except:
А
As a bronchodilator
О
Б
As a decongestant for rhinitis
О
В
To increase blood pressure
О
Г
Combined with local anesthetics
В
0080
Galazolin (Xylometazoline) is used in
treatment:
А
Rhinitis
О
Б
To increase blood pressure
О
В
Glaucoma
О
Г
Acute heart failure
В
0081 Dobutamine is used for all indications, except:
А
Bronchial asthma
О
Б
Atrioventricular block
О
В
Bradycardia
О
Г
Acute heart failure
В
0082 Indications of norepinephrine:
А
Vascular collapse
О
Б
Chronic hypotension
О
В
Atrioventricular block
О
Г
Anaphylactic shock
О
Д
Bronchospasm
The local vasoconstrictive effect of
В
0083 phenylephrine is used for all indications,
except:
А
To reduce edema of the bronchial mucosa
О
Б
To stop bleeding
О
В
Combined with local anesthetics
О
Г
Rhinitis
В
0084 Norepinephrine can cause:
А
Bradycardia
О
Б
Hypoglycemia
О
В
Miosis
О
Г
Bronchospasm
О
Д
Tissue ischemia
В
0085 Phenylephrine is:
А
All answers are correct
О
Б
Constricts blood vessels
О
В
Used to increase blood pressure
О
Г
О
Д
В
Local vasoconstrictor action is used for
rhinitis, to stop bleeding
α1-adrenoceptors agonist
0086 Side effects of ephedrine are all except:
А
Drowsiness
О
Б
Tachycardia
О
В
Insomnia
О
Г
Orthostatic hypertension
О
Д
Drug addiction
В
0087 For salbutamol is not typical:
А
It causes mild tachycardia
О
Б
Prescribed by inhalations
О
В
It is used to relieve bronchospasm
О
Г
Used for the threat of premature birth
В
0088 Adrenaline (epinephrine):
А
All answers are correct
О
Б
Reduces the tone of the bronchi
О
В
Effective only when administered parenterally
О
Г
May cause arrhythmia
О
Д
Acts briefly
О
Е
The drug of choice for anaphylactic shock
В
0089 Ephedrine:
А
All answers are correct
Relaxes the smooth muscles of the bronchi,
О
Б
has a stimulating effect on the central nervous
system
О
В
Increases blood pressure
О
Г
May cause drug dependence
О
Д
Has an indirect adrenomimetic effect
В
0090 β-adrenergic antagonists are all except:
А
Doxazosin
О
Б
Atenolol
О
В
Propranolol
О
Г
Timolol
О
Д
Metoprolol
О
Е
Bisoprolol
В
0091 a-, b- adrenergic antagonist:
А
Carvedilol
О
Б
Metoprolol
О
В
Propranolol
О
Г
Atenolol
О
Д
Bisoprolol
О
Е
Doxazosin
В
0092 Sympatholytic:
А
Reserpine
О
Б
Timolol
О
В
Doxazosin
О
Г
Propranolol
В
0093
b-adrenergic antagonists reduce everything
except:
А
Bronchial tone
О
Б
Heart rate
О
В
Atrioventricular conduction
О
Г
Purkinje fiber automatism
О
Д
Myocardial oxygen demand
О
Е
The strength of the heart contractions
В
0094
a-, b- adrenergic antagonists have all effects,
except:
А
Increased intestinal motility
О
Б
Decreased heart rate
О
В
Decrease in myocardial oxygen demand
О
Г
Decreased tone of blood vessels
О
Д
Decreased heart rate
В
0095
Propranolol is characterized by everything
except:
А
Increases the secretion of renin
О
Б
Slows down atrioventricular conduction
О
В
Reduces the automatism of cardiomyocytes
О
Г
Decreases blood pressure
О
Д
О
Е
В
Decreases heart rate and force of heart
contractions
Increases bronchial tone
0096 Carvedilol causes all effects except:
А
Decreased bronchial tone
О
Б
Slowing of atrioventricular conduction
О
В
Decreased blood pressure
О
Г
О
Д
Reduced automatism of Purkinje fibers
О
Е
Decrease in myocardial oxygen demand
В
0097
А
Decreased heart rate and force of heart
contractions
Tamsulosin blocks predominantly
adrenoceptors in:
Smooth muscles of the bladder neck and
prostatic urethra
О
Б
Smooth muscles of blood vessels
О
В
Cardiomyocytes
О
Г
Adipocytes
В
0098 The main effect of Tamsulosin:
А
Decreased tone of smooth muscles of the
bladder neck and prostatic urethra
О
Б
Hypotension
О
В
Decreased automatism of cardiomyocytes
О
Г
Bronchodilatory action
В
0099
А
b-adrenergic antagonists are effective in
coronary heart disease, because:
Reduce heart rate and reduce myocardial
oxygen demand
О
Б
Dilate blood vessels
О
В
Inhibit oxidative processes in the myocardium
О
Г
Reduces venous return
В
0100 b-adrenergic antagonists:
А
О
Б
О
В
О
Г
В
Reduce intraocular pressure without changing
pupil size
Narrowing the pupil and lowering intraocular
pressure
Dilate the pupil and increase intraocular
pressure
Do not affect pupil size and intraocular
pressure
0101 Tamsulosin is used for:
А
Benign prostatic hyperplasia
О
Б
Peripheral vasospasm
О
В
Hypertension
О
Г
Angina pectoris
В
0102
О
For Ischemic heart disease treatment effective
all drugs except:
А
Doxazosin
Б
Metoprolol
О
В
Atenolol
О
Г
Carvedilol
О
Д
Bisoprolol
О
Е
Propranolol
В
0103 Indications for carvedilol are all, except for:
А
Raynaud's disease
О
Б
Chronic heart failure
О
В
Hypertension
О
Г
Coronary heart disease
В
0104
Drug used to reduce intraocular pressure in
glaucoma:
А
Timolol
О
Б
Prazosin
О
В
Doxazosin
О
Г
Reserpine
В
0105
b1-, b2-adrenoceptors antagonists can cause
all side effects except:
А
Intestinal atony
О
Б
Suppression of atrioventricular conduction
О
В
Reducing myocardial contractility
О
Г
Bronchospasm
О
Д
Bradycardia
В
0106 Reserpine causes all side effects except:
А
Reflex tachycardia
О
Б
Depression
О
В
Parkinsonism
О
Г
Sedative effect
О
Д
Increased secretion of exocrine glands
О
Е
Increased intestinal motility
В
0107
А
Every characteristic is typical for Propofol,
except for:
It has a strong analgesic effect
Induces anesthesia 30-40 seconds after
О
Б
О
В
Acts for a short time (3-10 minutes)
О
Г
Recovery from anesthesia is quick
injection into a vein
Bradycardia, hypotension, and cardiac
В
0108 arrhythmias are caused by the following
general anesthetic:
А
Fluorothane (halothane)
О
Б
Nitrogen oxide (dinitrogen oxide)
О
В
Thiopental (sodium thiopental)
О
Г
Propofol
В
0109
Sensitivity of the myocardium to oxygen
increases by following general anesthetic:
А
Fluorothane (halothane)
О
Б
Thiopental (sodium thiopental)
О
В
Propofol
О
Г
Nitrogen oxide (dinitrogen oxide)
Administered by inhalation, has a high narcotic
В
0110
activity, causes bradycardia, decreases blood
pressure, sensitizes the myocardium to
adrenaline – it’s all about:
А
Fluorothane (halothane)
О
Б
Propofol
О
В
Nitrogen oxide (dinitrogen oxide)
О
Г
Ketamine
Administered by inhalation, has low narcotic
activity, is usually used in combination with
В
0111
active agents for anesthesia, does not cause
aftereffect, has a pronounced analgesic effect,
can be used to relieve pain in myocardial
infarction – it’s all about:
А
Nitrogen oxide (dinitrogen oxide)
О
Б
Ketamine
О
В
Thiopental (sodium thiopental)
О
Г
Fluorothane (Halothane)
В
0112
"Non-benzodiazepine" benzodiazepine
receptor agonist
А
Zolpidem
О
Б
Flumazenil
О
В
Diazepam
О
Г
Nitrazepam
В
0113 Diazepam's effects are all except:
А
Increased skeletal muscle tone
О
Б
Hypnotic
О
В
Anticonvulsant (antiepileptic)
О
Г
Anxiolytic
О
Д
Sedative
В
0114 Minimal effect on sleep structure provides:
А
Zolpidem
О
Б
Nitrazepam
О
В
Phenazepam
О
Г
Phenobarbital
В
0115
А
Nitrazepam characterized by everything
except for:
It relaxes the skeletal muscles by blocking
neuromuscular transmission
О
Б
Has anxiolytic effect
О
В
Has a hypnotic effect
О
Г
Interacts with benzodiazepine receptors
О
Д
Muscle relaxant of central action
О
Е
Has an anticonvulsant effect
О
Ж
May cause drug dependence
В
0116
The rebound phenomenon after
discontinuation of using hypnotics is due to:
А
Influence on the sleep structure
О
Б
Induction of liver microsomal enzymes
О
В
Material drugs cumulation
О
Г
Drug addiction
О
Д
H1-histamine receptors blockade
О
Е
Tolerance
В
0117
А
Regarding hypnotics, all statements are
correct, except:
Barbiturates do not cause drug dependence
Nitrazepam is less affects on sleep structure
О
Б
О
В
Diazepam has anxiolytic effect
О
Г
Zolpidem has little affect on sleep structure
О
Д
than barbiturates
Doxylamine is a H1-histamic receptors
antagonist (blocker)
Non-opioid drugs from different
В
0118 pharmacological groups that have analgesic
activity are all except:
А
Butorphanol
О
Б
Amitriptyline
О
В
Carbamazepine
О
Г
Ketamine
О
Д
Nitrogen oxide (dinitrogen oxide)
О
Е
Gabapentin
В
0119 Non-opioid analgesics with central action:
А
Paracetamol
О
Б
Butorphanol
О
В
Buprenorphine
О
Г
Morphine
О
Д
Metamizole sodium (analgin)
Analgesics from the group of full opioid
В
0120 receptor agonists cause all pharmacological
effects except:
А
Antipyretic effect
О
Б
Euphoria
О
В
Respiratory depression
О
Г
Analgesia
О
Д
Drug addiction
О
Е
Constipation
О
Ж
Miosis
В
0121
Buprenorphine is characterized by everything
except:
А
Opioid mu-receptors agonist
О
Б
Partial opioid mu-receptors agonist
О
В
Opioid analgesic
О
Г
О
Д
В
0122
Less than morphine causes respiratory
depression
Less frequently than morphine causes drug
dependence
An opioid analgesic used for neurolept
analgesia is:
А
Fentanyl
О
Б
Paracetamol
О
В
Amitriptyline
О
Г
Morphine
В
0123
Acute morphine poisoning is characterized by
all effects except:
А
Psychomotor agitation
О
Б
Coma
О
В
Respiratory depression
О
Г
Miosis
В
0124 The analgesic effect of Amitriptyline is due to:
А
Activation of adrenergic and serotonergic
transmission in CNS
О
Б
By opioid receptors activation
О
В
Stimulation of GABAergic processes
О
Г
Decreased production of prostaglandins in
CNS
Opium alkaloid; has an analgesic effect;
В
0125 euphoric; depresses breathing; used for
traumatic and postoperative pain is:
А
Morphine
О
Б
Tramadol
О
В
Promedol (trimeperidine)
О
Г
Fentanyl
Non-opioid analgesic; has an analgesic and
В
0126 antipyretic effect, almost has no antiinflammatory properties:
А
Paracetamol
О
Б
Ketamine
О
В
Amitriptyline
О
Г
Carbamazepine
В
0127
А
All statements regarding central analgesics are
correct, except:
Promedol (trimeperidine) - non-opioid
analgesic
О
Б
Morphine can cause euphoria
О
В
Paracetamol has no anti-inflammatory effect
О
Г
В
Carbamazepine is used for trigeminal
neuralgia
0128 The antipsychotic effect is explained by:
А
Dopaminergic inhibition processes in the CNS
О
Б
Adrenergic inhibition processes in the CNS
О
В
О
Г
В
0129
Dopaminergic stimulation processes in the
CNS
Adrenergic stimulation processes in the CNS
Aminazine (chlorpromazine) is characterized
by everything except for:
А
Has an antidepressant effect
О
Б
Has a sedative effect
О
В
Reduces motor activity
О
Г
О
Д
Has antiemetic effect
О
Е
Causes extrapyramidal disorders
В
0130
А
Eliminates productive symptoms of psychosis
(delusions, hallucinations)
Clozapine is characterized by all the following
statement except:
Has antidepressant properties
Reduces negative symptoms of psychosis
О
Б
(decreased motivation, depression of
emotions)
Reduces productive symptoms of psychosis
О
В
О
Г
May cause leukopenia, agranulocytosis
О
Д
Rarely causes extrapyramidal disorders
В
(delusions, hallucinations)
0131 Antipsychotic drugs are not used:
А
For the treatment of parkinsonism
О
Б
For vomiting of CNS origin
О
В
О
Г
For the treatment of psychosis
О
Д
For relief of acute psychomotor agitation
В
0132
To enhance the action of anesthetics, opioid
analgesics
For correction of extrapyramidal disorders
caused by antipsychotic agents are used:
А
Central cholinergic antagonists
О
Б
Dopaminergic agonists
О
В
MAO-B inhibitors
О
Г
Muscle relaxants
For correction of extrapyramidal disorders
В
0133 caused by antipsychotic agents the next drug
is used:
А
Cyclodol (trihexyphenidyl)
О
Б
Levodopa
О
В
Bromocriptine
О
Г
Selegiline
В
0134 Which drug is not an antidepressant?
А
Haloperidol
О
Б
Imizine (imipramine)
О
В
Moclobemide
О
Г
Maprotiline
О
Д
Amitriptyline
В
0135
Antidepressant drug - selective inhibitor of
neuronal serotonin uptake is:
А
Fluvoxamine
О
Б
Amitriptyline
О
В
Moclobemide
О
Г
Maprotiline
Eliminates the productive symptoms of
psychosis (delirium, hallucinations); has
sedative and antiemetic effects, causes
В
0136 extrapyramidal disturbances, lowers blood
pressure, reduces or "perverts" the
vasopressor effect of adrenaline – it’s all
about:
А
Aminazine (chlorpromazine)
О
Б
Amitriptyline
О
В
Sulpirid
О
Г
Lithium carbonate
Antipsychotic; the psychosedative effect is
less than that of chlorpromazine
В
0137 (chlorpromazine); less decreases blood
pressure, often causes extrapyramidal
disorders – it’s all about:
А
Haloperidol
О
Б
Amitriptyline
О
В
Sulpirid
О
Г
Maprotiline
Eliminates the productive symptoms of
В
0138
psychosis (delusions, hallucinations), rarely
causes extrapyramidal disorders, can cause
agranulocytosis – it’s all about:
А
Aminazine (chlorpromazine)
О
Б
Amitriptyline
О
В
Clozapine
О
Г
Fluoxetine
О
Д
Haloperidol
Causes antidepressant and sedative effects,
В
0139 non-selectively inhibits the neuronal uptake of
monoamines (norepinephrine and serotonin):
А
Amitriptyline
О
Б
Lithium carbonate
О
В
Fluoxetine
О
Г
Maprotiline
О
Д
Chlorpromazine
Has antidepressant and psychoactive
В
0140
properties selectively inhibits neuronal uptake
of serotonin, does not have an atropine-like
effect – it’s all about:
А
Fluvoxamine
О
Б
Amitriptyline
О
В
Maprotiline
О
Г
Imizine (imipramine)
О
Д
Chlorpromazine
В
0141
А
All statements regarding antipsychotics and
antidepressants are correct except:
Fluoxetine has strong atropine-like effect
Maprotiline inhibits neuronal uptake of
О
Б
О
В
О
Г
Droperidol is used for neurolept analgesia
О
Д
Amitriptyline has no psychostimulant effect
В
monoamines
Clozapine rarely causes drug-induced
parkinsonism
0142 A non-anxiolytic drug is:
А
Piracetam
О
Б
Buspirone
О
В
Phenazepam
О
Г
Mesapam (medazepam)
О
Д
Diazepam
В
0143
The drug, which is an anxiolytic - serotonin
receptor agonist is:
А
Buspirone
О
Б
Diazepam
О
В
Phenazepam
О
Г
Mesapam (Medazepam)
В
0144 Diazepam's effects are all listed, except:
А
Antipsychotic
О
Б
Anticonvulsant
О
В
Hypnotic
О
Г
Anxiolytic
О
Д
Decreased skeletal muscle tone
О
Е
Sedative
О
Ж
Amnestic (memory impairment)
The benzodiazepine group’s anxiolytics
В
0145 enhance GABAergic processes in the brain due
to:
А
Increasing the sensitivity of GABA receptors to
the mediator
Suppression of the enzyme that inactivates
О
Б
О
В
Direct stimulation of GABA receptors
О
Г
Stimulating GABA synthesis
В
0146
GABA
Diazepam is characterized by everything
except:
А
Causing extrapyramidal disorders
О
Б
Has anxiolytic activity
О
В
Has anticonvulsant activity
О
Г
Enhances GABA-ergic processes in the CNS
О
Д
Central muscle relaxant action
В
0147 The main effect of valerian preparations:
А
Sedative
О
Б
Antidepressant
О
В
Antipsychotic
О
Г
Anxiolytic
В
0148 Which effect sydnocarb (mesocarb) causes:
А
Reducing the need for sleep
Temporary decreased mental and physical
О
Б
О
В
Lowering blood pressure
О
Г
Decreased skeletal muscle tone
В
performance
0149 Caffeine causes all effects except:
А
Decreased skeletal muscle tone
О
Б
Reducing the need for sleep
О
В
О
Г
О
Д
Increased strength and heart rate
О
Е
Increased secretion of stomach glands
В
Temporary increase in mental and physical
performance
Increased activity of the respiratory and
vasomotor centers
0150 Sydnocarb (mesocarb) is used:
А
О
Б
О
В
In narcolepsy (pathological sleepiness)
To eliminate delirium and hallucinations in
psychosis
To eliminate emotional stress, anxiety and fear
in neuroses
В
0151 Which drugs is a nootropic agent?
А
Piracetam
О
Б
Sydnocarb (mesocarb)
О
В
Mesapam (medazepam)
О
Г
Caffeine
О
Д
Lobelin
В
0152
Which drug is used in mental deficiency
associated with organic brain lesions?
А
Piracetam
О
Б
Sydnocarb (mesocarb)
О
В
Diazepam
О
Г
Caffeine
This drug has anxiolytic, hypnotic,
В
0153
anticonvulsant properties; administered orally
and intravenously; used for neuroses,
insomnia, for relief of status epilepticus:
А
Diazepam
О
Б
Piracetam
О
В
Sydnocarb (mesocarb)
О
Г
Mesapam (medazepam)
Anxiolytic drug with benzodiazepine structure,
В
0154 it has mild sedative and hypnotic effects; used
for neuroses, can be used in the daytime:
А
Mesapam (medazepam)
О
Б
Diazepam
О
В
Phenazepam
О
Г
Sydnocarb (mesocarb)
It stimulates mental and physical performance,
has little effect on the cardiovascular system;
В
0155 used for pathological drowsiness, asthenic
conditions; side effects are insomnia and
anxiety:
А
Sydnocarb (mesocarb)
О
Б
Mesapam (medazepam)
О
В
Caffeine
О
Г
Piracetam
В
0156
All of the following is characteristic of
Camphor, except:
А
Drug addiction
О
Б
Stimulates the respiratory center
О
В
Has a local irritant effect
О
Г
Stimulates the vasomotor center
О
Д
It has a direct stimulatory effect on the heart
О
Е
Used to stimulate breathing
В
0157 Caffeine is used for all indications, except for:
А
Hypertension
О
Б
Hypotension
О
В
As a respiratory stimulant
О
Г
As a psychostimulant
О
Д
Migraine
В
0158
In case of caffeine overdose, which one effect
is not possible?
А
Collapse
О
Б
Tachycardia
О
В
Insomnia
О
Г
Cardiac arrhythmia
В
0159 Antitussive agent of peripheral action:
А
Libexin (prenoxydiazine)
О
Б
Codeine
О
В
Glaucin
О
Г
Guaifenesin
В
0160 Expectorant of reflex action:
А
Infusion of thermopsis herb
О
Б
Potassium iodide
О
В
Sodium bicarbonate
О
Г
Trypsin
О
Д
Acetylcysteine
В
0161
Which pharmacological group provides
bronchodilator effect?
А
β2-Adrenomimeics
О
Б
α-blockers
О
В
Ganglion blockers
О
Г
β1-blockers
О
Д
M-cholinomimetics
В
0162 Myotropic bronchodilator is:
А
Theophylline
О
Б
Formoterol
О
В
Cromolyn Sodium (as Sodium Cromoglycate)
О
Г
Montelukast
О
Д
Tiotropium
О
Е
Ephedrine
В
0163
Which group of drugs is not used in bronchial
asthma?
А
Analeptics
О
Б
β2-Adrenomimetics
О
В
Glucocorticoids
О
Г
M-cholinergic antagonists
О
Д
Leukotriene-receptor blockers
В
0164 Select leukotriene-receptor blocker drug:
А
Montelukast
О
Б
Cromoglicic acid
О
В
Ipratropium bromide
О
Г
Beclomethasone
В
0165
Cytisine stimulates respiration due to Ncholinergic receptors activation of:
А
Carotid glomeruli
О
Б
Chromaffin cells of the adrenal medulla
О
В
Vegetative ganglia
О
Г
Respiratory muscles
В
0166
А
The antitussive effect of Libexin
(prenoxydiazine) is due to:
Inhibition of sensitive receptors of the afferent
pathways
О
Б
Bronchodilator action
О
В
Decreased secretion of bronchial glands
О
Г
В
0167
Suppression of the excitability of neurons in
the cough center
Which drug reduces the viscosity of sputum
due to proteolysis?
А
Trypsin
О
Б
Thermopsis preparations
О
В
Sodium bicarbonate
О
Г
Ambroxol
В
0168 Acetylcysteine:
Reduces the viscosity of sputum due to the
А
destruction of disulfide bonds of
proteoglycans
О
Б
О
В
О
Г
В
0169
Has a direct stimulating effect on the bronchial
glands
Reflexively stimulates the secretion of the
bronchial glands
Suppresses the excitability of neurons in the
cough center
The bronchodilator effect of adrenaline
(epinephrine) is due to:
А
β2-adrenergic receptors stimulation
О
Б
β1-adrenergic receptors stimulation
О
В
α-adrenergic receptors stimulation
О
Г
В
0170
Direct relaxing effect on bronchial smooth
muscles
Ipratropium and tiotropium reduce bronchial
muscle tone due to:
А
M3-cholinergic receptors inhibition
О
Б
М2-cholinergic receptors inhibition
О
В
M1-cholinergic receptors inhibition
О
Г
β1-adrenergic receptors stimulation
О
Д
β2-adrenergic receptors stimulation
В
0171
Relaxation of the bronchi muscles is caused by
substances which:
А
Activate adenylate cyclase
О
Б
Inhibit adenylate cyclase
О
В
Activate phospholipase C
О
Г
Activate phospholipase A2
All of the following drugs reduce the release of
В
0172 bronchoconstrictor substances from mast
cells, except:
А
Montelukast
О
Б
Fluticasone
О
В
Cromolyn sodium (sodium cromoglycate)
О
Г
Theophylline
О
Д
Salbutamol
В
0173 Prenoxdiazine:
А
Depresses the cough reflex
О
Б
Causes drug dependence
О
В
Has sedative properties
О
Г
Provide respiratory depression
В
0174 Acetylcysteine:
А
Reduces the viscosity of bronchial secretions
О
Б
Increases the volume of bronchial secretions
О
В
Depresses the cough reflex
О
Г
Relaxes smooth muscles of bronchi
В
0175 In pulmonary edema ethyl alcohol is used as:
А
Antifoaming agent/Defoamer
О
Б
Analgesics
О
В
Antimicrobial agent
О
Г
Narcotic drug
О
Д
Vasodilator
В
0176 Which drug can cause drug dependence?
А
Codeine
О
Б
Glaucin
О
В
Butamirate
О
Г
Acetylcysteine
В
0177
Glucocorticoids used in inhalation form can
cause:
А
Oral candidiasis
О
Б
Edema of the bronchial mucosa
О
В
Inhibition of bronchial glands secretion
О
Г
Suppression of the adrenal cortex function
Which statement regarding drugs that affect
В
0178 the functions of the respiratory system is
correct?
А
Codeine has an analgesic effect
О
Б
Glaucin stimulates the respiratory center
О
В
Salbutamol blocks β2-adrenergic receptors
О
Г
В
0179
Sodium nitroprusside is an effective
bronchodilator
Compared to Salbutamol, Salmeterol has next
properties:
А
Has a longer bronchodilator effect
О
Б
Short-term action
О
В
Reduces the tone of blood vessels
О
Г
Oral efficacy
Bronchodilator from the M-cholinergic
В
0180 agonists group characterized by each
following statement except:
А
О
Б
О
В
О
Г
О
Д
Reduce swelling of the bronchial mucosa
Relax the smooth muscles of the bronchi due
to blockade of M3-cholinergic receptors
Reduce the secretion of bronchial glands
Suppress the release of bronchoconstrictive
substances from mast cells
Contraindicated in glaucoma
Determine the bronchodilator: administered
В
0181
parenterally; acts for a short time; used only to
relieve bronchospasm; causes severe
tachycardia; increases blood pressure:
А
Adrenaline (epinephrine)
О
Б
Ephedrine
О
В
Tiotropium
О
Г
Theophylline
О
Д
Salbutamol
Determine the bronchodilator: effective when
В
0182
administered orally; acts for several hours;
causes tachycardia; increases blood pressure;
can cause drug dependence:
А
Ephedrine
О
Б
Salmeterol
О
В
Salbutamol
О
Г
Theophylline
О
Д
Atropine
Determine bronchodilator: used mainly to
В
0183 relieve bronchospasm; reduces the tone of
blood vessels; can cause mild tachycardia:
А
Salbutamol
О
Б
Atropine
О
В
Ephedrine
О
Г
Ipratropium bromide
Determine a bronchodilator: prescribed by
В
0184
inhalation; reduces the secretion of the
salivary and bronchial glands; contraindicated
in glaucoma:
А
Ipratropium
О
Б
Ephedrine
О
В
Theophylline
О
Г
Salmeterol
Determine bronchodilator: used to prevent and
relieve bronchospasm; administered internally
В
0185 and parenterally; causes tachycardia; has a
vasodilating effect; stimulates the central
nervous system:
А
Euphyllin (aminophylline)
О
Б
Ephedrine
О
В
Ipratropium bromide
О
Г
Salbutamol
В
0186 Montelukast’s mechanism of action:
А
Blocks leukotriene receptors
О
Б
Inhibits 5-lipoxygenase
О
В
Inhibits phospholipase A2
О
Г
Inhibits cyclooxygenase
В
0187
А
О
Б
О
В
В
After β2-adrenergic receptors stimulation in
the muscle fibers of the bronchi:
The concentration of cAMP increases and the
concentration of calcium ions decreases
The concentration of cAMP decreases and the
concentration of calcium ions decreases
The concentration of cAMP increases and the
concentration of calcium ions increases
0188 Non-glycosidic cardiotonic drug:
А
Levosimendan
О
Б
Strofantin
О
В
Digoxin
О
Г
Celanide
В
0189 Digitalis glycoside drug:
А
Digoxin
О
Б
Levosimendan
О
В
Dobutamine
О
Г
Strofantin
В
0190 Cardiotonic drug of glycosidic structure:
А
Strofantin
О
Б
Dopamine
О
В
Dobutamine
О
Г
Levosimendan
В
0191
Cardiotonic drug that increases affinity of
actin and myosin for calcium ions:
А
Levosimendan
О
Б
Digoxin
О
В
Dopamine (dopamine)
О
Г
Dobutamine
В
0192
In case of intoxication with cardiac glycosides,
everything is used except:
А
Digoxin
О
Б
Lidocaine
О
В
Atropine
О
Г
Potassium chloride
В
0193 Dobutamine stimulates:
А
О
Б
О
В
О
Г
В
0194
Predominantly β1-adrenergic receptors of the
heart
Predominantly β2-adrenergic receptors of the
heart
Both β1- and β2-adrenergic receptors of the
heart
Dopamine receptors
Cardiotonic drug that inhibits Na +, K + ATPase:
А
Digoxin
О
Б
Dobutamine
О
В
Levosimendan
О
Г
Dopamine
В
0195
In acute heart failure, each drug is used
except:
А
Phenytoin
О
Б
Digoxin
О
В
Dobutamine
О
Г
Dopamine (dopamine)
В
0196
Signs of intoxication with cardiac glycosides
are all except:
А
Arterial hypotension
О
Б
Nausea and vomiting
О
В
Atrioventricular block
О
Г
Extrasystole
О
Д
Blurred vision
В
0197
Each of the following statement is true for
Digoxin except:
А
Facilitates atrioventricular conduction
О
Б
Decreases heart rate
О
В
Increases the heart strength
О
Г
Used for heart failure
О
Д
Used for tachyarrhythmic atrial fibrillation
В
0198
Each of the following statement is true for
Levosimendan except:
А
Used for chronic heart failure
О
Б
Dilates peripheral blood vessels
О
В
Dilates coronary vessels
О
Г
Increases the heart strength
О
Д
Used for acute heart failure
Determine a drug: cardiac glycoside, used in
В
0199
acute and chronic heart failure,
tachyarrhythmic form of atrial fibrillation, is
administered orally and intravenously:
А
Digoxin
О
Б
Levosimendan
О
В
Strofantin
О
Г
Dobutamine
О
Д
Digitoxin
Determine a drug: it increases the strength of
heart contractions without increasing the
concentration of calcium ions in
В
0200 cardiomyocytes, increasing the sensitivity of
myofibrils to calcium, dilates vessels of the
systemic circulation and coronary vessels;
used in acute heart failure:
А
Levosimendan
О
Б
Dopamine (Dopamine)
О
В
Digoxin
О
Г
Strofantin
О
Д
Dobutamine
О
Е
Digitoxin
В
0201
All of the following drugs are sodium channel
blockers except:
А
Verapamil
О
Б
Diphenin (phenytoin)
О
В
Novocainamide (procainamide)
О
Г
Allapinin (lappaconitine)
О
Д
Quinidine
В
0202 Calcium channel blocker:
А
Verapamil
О
Б
Diphenin (phenytoin)
О
В
Lidocaine
О
Г
Allapinin (lappaconitine)
О
Д
Propafenone
В
0203
An antiarrhythmic agent that eliminates
adrenergic effects on the heart:
А
Metoprolol
О
Б
Diphenin (phenytoin)
О
В
Atropine
О
Г
Lidocaine
О
Д
Propafenone
В
0204 Amiodarone and sotalol are used in patients:
А
With ventricular and supraventricular
arrhythmias
О
Б
Only with supraventricular arrhythmias
О
В
Only with ventricular arrhythmias
О
Г
With atrioventricular block
В
0205 Verapamil is used in patients:
А
Mainly with supraventricular arrhythmias
О
Б
Only with ventricular arrhythmias
О
В
With tachyarrhythmias
О
Г
With atrioventricular block
В
0206
Subclass IA sodium channel blockers can
cause all side effects except:
А
Increased blood pressure
О
Б
Arrhythmias
О
В
Atrioventricular block
О
Г
Decreased myocardial contractility
В
0207 The side effects of amiodarone are all except:
А
Arterial hypertension
О
Б
Deposition of microcrystals in the cornea
О
В
Skin pigmentation, photodermatitis
О
Г
Thyroid dysfunction
В
0208 Everything is suitable for Amiodarone except:
А
О
Б
О
В
May cause bronchospasm
Used for ventricular and supraventricular
arrhythmias
May cause impaired thyroid function
Strongly blocks potassium channels of
О
Г
cardiomyocytes, as well as sodium and
calcium channels
В
0209
Antianginal agent from the potassium channel
activators group:
А
Nicorandil
О
Б
Verapamil
О
В
Ivabradine
О
Г
Bisoprolol
О
Д
Isosorbide monohydrate
В
0210 Bisoprolol refers to:
А
β1-blockers
О
Б
β1- and β2-blockers
О
В
Calcium channel blockers
О
Г
Potassium channel activators
В
0211 Myotropic coronary dilator is:
А
Dipyridamole
О
Б
Trimetazidine
О
В
Metoprolol
О
Г
Anaprilin (propranolol)
О
Д
Ivabradine
В
0212 Cardioprotective agent:
А
Trimetazidine
О
Б
Nifedipine
О
В
Ivabradine
О
Г
Isosorbide mononitrate
В
0213
А
The effects of antianginal drugs - calcium
channel blockers are all except:
Increase the resistance of cardiomyocytes to
ischemia
О
Б
Increase oxygen delivery to the myocardium
О
В
Reduce myocardial oxygen demand
О
Г
Reduce the tone of the coronary vessels
В
0214
Nifedipine differs from verapamil in all of the
following except:
А
It affects the tone of the coronary vessels
О
Б
Has no antiarrhythmic effect
О
В
It has a strong hypotensive effect
О
Г
В
membranes of cardiomyocytes
0215 Nicorandil effects - all listed, except:
А
О
Б
О
В
О
Г
В
Almost no effect on the calcium channels of
Decreases heart rate
Dilates coronary vessels and increases the
delivery of oxygen to the myocardium
Dilates the arteries and reduces the afterload
on the heart
Dilates veins and reduces preload on the heart
0216 Ivabradine:
А
Reduces the cardiac oxygen demand
Reduces the cardiac oxygen demand and
О
Б
О
В
Increases oxygen supply to the myocardium
О
Г
Has a cardioprotective effect
В
increases its blood supply at the same time
0217 Mainly for relief of angina attacks are used:
А
Short-acting nitroglycerin drugs (tablets and
spray for sublingual use)
О
Б
Long-acting nitroglycerin preparations
О
В
Isosorbide monohydrate
О
Г
Nitrosorbide (isosorbide dinitrate)
В
0218
Drugs for migraine attacks relief all of the
following except:
А
Vinpocetine
О
Б
Ergotamine
О
В
Sumatriptan
О
Г
Acetylsalicylic acid
О
Д
Dihydroergotamine
В
0219 Angiotensin-converting enzyme inhibitor:
А
Enalapril
О
Б
Losartan
О
В
Amlodipine
О
Г
Indapamide
О
Д
Metoprolol
В
0220 Angiotensin receptor antagonist:
А
Losartan
О
Б
Metoprolol
О
В
Doxazosin
О
Г
Enalapril
О
Д
Carvedilol
В
0221
Myotropic antihypertensive drugs, all of the
following except:
А
Reserpine
О
Б
Nifedipine
О
В
Sodium nitroprusside
О
Г
Amlodipine
В
0222
For clonidine (clonidine), all of the following is
suitable except:
А
Stimulates the central nervous system
О
Б
Reduces the tone of the vasomotor centers
О
В
Lowers blood pressure
Stimulates α2-adrenergic receptors and I1-
О
Г
imidazoline receptors of the solidary tract
neurons
О
Д
В
0223
Causes sedative and hypnotic effects
The mechanism of the vasodilating action of
doxazosin:
А
Blocks α1-adrenergic receptors
О
Б
Blocks AT1-angiotensin receptors
О
В
Activates potassium channels
О
Г
Blocks calcium channels
В
0224
А
Losartan lowers the activity of the reninangiotensin system, since:
Blocks AT1-angiotensin receptors, eliminating
the action of angiotensin II
О
Б
Inhibits renin
О
В
Inhibits angiotensin converting enzyme
О
Г
Inhibits the secretion of renin
В
0225
The mechanism of the vasodilating action of
amlodipine and nifedipine:
А
Block calcium channels
О
Б
Block α1-adrenergic receptors
О
В
Activate potassium channels
О
Г
Block AT1-angitensin receptors
Diuretics that have a direct effect on the
В
0226 function of the renal tubule’s epithelium everything except:
А
Mannitol
О
Б
Furosemide
О
В
Chlorthalidone
О
Г
Triamteren
О
Д
Indapamide
О
Е
Hydrochlorothiazide
В
0227 Aldosterone antagonist:
А
Spironolactone
О
Б
Furosemide
О
В
Mannitol
О
Г
Hydrochlorothiazide
О
Д
Indapamide
В
0228 Osmotic diuretic:
А
Mannitol
О
Б
Chlorthalidone
О
В
Furosemide
О
Г
Indapamide
О
Д
Triamteren
В
0229 The main localization of the furosemide action:
А
Thick segment of the ascending part of the
loop of Henle
О
Б
Proximal canals
О
В
Initial section of distal tubules
О
Г
End section of distal tubules
Against the background of the action of
В
0230 furosemide, the excretion of everything by the
kidneys increases, except for:
А
Uric acid
О
Б
Chlorine ions
О
В
Potassium ions
О
Г
Magnesium ions
О
Д
Calcium ions
О
Е
Sodium ions
В
0231
А
О
Б
О
В
О
Г
В
0232
А
О
Б
О
В
О
Г
В
0233
All of the following is characteristic of
indapamide, except:
Acts on the terminal section of the distal
tubules
Increases the excretion of sodium and chlorine
ions from the body
Increases the excretion of potassium and
magnesium ions from the body
Has a hypotensive effect
For spironolactone, all of the following is
characteristic, except:
Inhibits the synthesis of aldosterone
Blocks aldosterone receptors and eliminates
the effect of aldosterone on the renal tubules
Increases the excretion of potassium and
magnesium ions by the kidneys
The severity of the diuretic effect depends on
the level of aldosterone in the body.
Indications for the use of diuretics are all of
the following, except:
А
Treatment of arterial hypotension
О
Б
Treating edema in congestive heart failure
О
В
Hypertension treatment
О
Г
О
Д
В
Forced diuresis (acceleration of the elimination
of toxic substances from the body)
Treatment of acute edema (lung, brain)
0234 In pulmonary edema is used:
А
Furosemide
О
Б
Indapamide
О
В
Hydrochlorothiazide
О
Г
Spironolactone
В
0235
In arterial hypertension, all of the following is
used, except:
А
Mannitol
О
Б
Hydrochlorothiazide
О
В
Furosemide
О
Г
Indapamide
О
Д
Chlorthalidone
В
0236
А
Furosemide is used for all indications, except
for:
To prevent hypokalemia caused by
hydrochlorothiazide
О
Б
With congestive heart failure
О
В
With edema of the lungs and brain
О
Г
For forced diuresis
О
Д
With arterial hypertension
В
0237
Hypochloremic alkalosis can develop with the
use of all diuretics, except for:
А
Mannitol
О
Б
Hydrochlorothiazide
О
В
Indapamide
О
Г
Furosemide
В
0238 Hearing loss is possible with prolonged use of:
А
Furosemide
О
Б
Triamterene
О
В
Spironolactone
О
Г
Hydrochlorothiazide
В
0239
Side effects of furosemide are all of the
following, except:
А
Acidosis
О
Б
Hypomagnesemia
О
В
Hyperuricemia
О
Г
Hyperglycemia
О
Д
Ototoxicity
О
Е
Hypokalemia
Determine the diuretic: has a low diuretic
efficacy; reduces the excretion of potassium
В
0240 and magnesium ions from the body; the effect
of the drug does not depend on the level of
aldosterone in the body:
А
Triamterene
О
Б
Furosemide
О
В
Indapamide
О
Г
Mannitol
В
0241 Anorexigenic drugs (reducing appetite):
А
Sibutramine
О
Б
Metoclopramide
О
В
Omeprazole
О
Г
Ranitidine
О
Д
Loperamide
В
0242 Proton pump inhibitor (H+, K+ -ATPase):
А
Omeprazole
О
Б
Pirenzepine
О
В
Ranitidine
О
Г
Misoprostol
В
0243 Histamine H2 receptor blocker:
А
Ranitidine
О
Б
Sibutramine
О
В
Pirenzepine
О
Г
Metoclopramide
О
Д
Omeprazole
В
0244 An agent from the M1-anticholinergic group:
А
Pirenzepine
О
Б
Omeprazole
О
В
Ranitidine
О
Г
Atropine
В
0245 All listed drugs are antacids, except:
А
Magnesium sulfate
О
Б
Magnesium oxide
О
В
Sodium bicarbonate
О
Г
Aluminum hydroxide
О
Д
Calcium carbonate
В
0246
Gastroprotective drug which is a synthetic
analogue of prostaglandin E:
А
Misoprostol
О
Б
Bismuth tripotassium dicitrate
О
В
Sucralfate
О
Г
Vikair
В
0247 Antiemetics - all listed, except:
А
Apomorphine
О
Б
Domperidone
О
В
Ondansetron
О
Г
Dimenhydrinate
О
Д
Metoclopramide
В
0248 Antiemetic - D-dopamine receptor blocker:
А
Metoclopramide
О
Б
Ondansetron
О
В
Granisetron
О
Г
Thriethylpyrazine
В
0249 Antiemetic histamine H1-receptor blocker:
А
Dimenhydrinate
О
Б
Metoclopramide
О
В
Scopolamine
О
Г
Ondansetron
В
0250 Prokinetic (gastrokinetic) agent:
А
Metoclopramide
О
Б
Onadansterone
О
В
Omeprazole
О
Г
Ranitidine
О
Д
Atropine
В
0251 Choleretic drugs are all of the listed, except:
А
Ranitidine
О
Б
Holosas
О
В
Drotaverin (no-shpa)
О
Г
Atropine
О
Д
Cholenzym
В
0252
Gallstone dissolving agent (cholelitholytic
agent):
А
Ursodeoxycholic acid
О
Б
Holosas
О
В
Ademetionine
О
Г
Cholenzym
О
Д
Berberine
В
0253
An anticholinesterase agent that stimulates
intestinal motility:
А
Neostigmine
О
Б
Loperamide
О
В
Sodium picosulfate
О
Г
Atropine
О
Д
Magnesium sulfate
О
Е
Castor oil
В
0254
Laxatives containing anthraglycosides are all
listed, except:
А
Castor oil
О
Б
Buckthorn bark preparations
О
В
Rhubarb root preparations
О
Г
В
0255
А
О
Б
О
В
О
Г
В
0256
Senna leaf preparations
Omeprazole is characterized by all of the
following, except:
Histamine H2 receptor blocker
Selectively affects the parietal cells of the
stomach
Significantly reduces the secretion of gastric
glands
Proton pump inhibitor (H +, K + -ATPase)
All of the following is characteristic of
Omeprazole, except:
А
Forms active metabolites at neutral pH
О
Б
Is a prodrug
О
В
О
Г
В
Forms active metabolites in the acidic
environment of the tubules of parietal cells
Active metabolites inhibit the proton pump (H
+, K + -ATPase) irreversibly
0257 Ranitidine is characterized by:
А
Blocks histamine H2 receptors
О
Б
Blocks M-cholinergic receptors
О
В
Increases the secretion of hydrochloric acid
О
Г
О
Д
В
0258
Reduces the release of histamine from
enterochromaffin-like cells in the stomach
Coats the mucous membrane
Misoprostol works on the stomach and causes
all of the following, except:
А
Covers the ulcerative surface
О
Б
Increases mucus secretion
О
В
Improves microcirculation
О
Г
Reduces the secretion of hydrochloric acid
О
Д
Stimulates the regeneration of mucosal cells
О
Е
Increases the secretion of bicarbonate
В
0259
Atropine acts on the digestive system and
causes all of the following effects, except:
А
Increased gastric motility
О
Б
Decreased secretion of hydrochloric acid
О
В
О
Г
Decreased bowel tone and motility
О
Д
Decreased secretion of salivary glands
В
0260
Relaxation of the sphincter of Oddi and relief
of bile secretion
For gastric ulcer and duodenal ulcer, all of the
following drugs are used, except:
А
Drugs that increase appetite
О
Б
Antacids
О
В
Gastroprotectors
О
Г
О
Д
В
0261
Antimicrobial agents effective against
Helicobacter pylori
Agents that reduce the secretion of
hydrochloric acid
For hyperacid gastritis, everything is used
except
А
Blockers of histamine H1 receptors
О
Б
Histamine H2 receptor blockers
О
В
Antacids
О
Г
M-anticholinergics
О
Д
Proton pump blockers
В
0262 Misoprostol is used:
А
О
Б
О
В
О
Г
В
0263
To prevent the ulcerogenic action of NSAIDs
To suppress vomiting when using cytostatic
agents
To stop bleeding from the veins of the
esophagus
For the treatment of chronic constipation
Metoclopramide is used for all indications,
except for:
А
With motion sickness
О
Б
With vomiting in the postoperative period
О
В
Vomiting caused by ionizing radiation
О
Г
О
Д
В
When the evacuation of stomach contents is
delayed
For gastroesophageal reflux
0264 Ademetionine and legalon are used as:
А
Hepatoprotectors
О
Б
Prokinetics (gastrokinetics)
О
В
Gastroprotectors
О
Г
Laxatives
В
0265 Ursodeoxycholic acid is used:
А
О
Б
О
В
О
Г
В
For dissolving small cholesterol stones in the
gallbladder
To increase appetite
As a means of replacement therapy for
insufficient pancreatic function
As a means of stimulating the secretion of bile
0266 Atropine is used in all cases, except for:
А
For constipation
With spastic conditions of the intestines and
О
Б
О
В
To facilitate the outflow of bile
О
Г
To reduce increased salivation
В
stomach
0267 Loperamide is used:
А
For noninfectious diarrhea
О
Б
With postoperative intestinal atony
О
В
О
Г
В
To reduce the absorption of toxic substances
from the intestines in case of poisoning
As a hepatoprotective agent
0268 Indications for the use of proserin:
А
Intestinal atony
О
Б
Diarrhea
О
В
Intestinal colic
О
Г
Constipation
В
0269
For chronic constipation are used laxatives
which:
А
Acting mainly on the large intestine
О
Б
Acting throughout the entire intestine
О
В
Acting primarily on the small intestine
О
Г
Effective only in the rectal area
В
0270
For chronic constipation, all of the following
drugs are used, except:
А
Castor oil
О
Б
Rhubarb preparations
О
В
Senna preparations
О
Г
Buckthorn preparations
О
Д
Lactulose
О
Е
Sodium picosulfate
All of the following drug is used in the
В
0271
treatment of poisoning to reduce the
absorption of toxic substances from the
intestines:
А
Saline laxatives
О
Б
Sodium picosulfate
О
В
Senna preparations
О
Г
Castor oil
О
Д
Buckthorn preparations
В
0272
The side effects of atropine are all listed,
except:
А
Spasm of accommodation
О
Б
Tachycardia
О
В
Increased intraocular pressure
О
Г
Constipation
О
Д
Delayed urination
О
Е
Dry mouth
Unlike atropine, pirenzepine in therapeutic
В
0273 doses has little effect on all indicators, except
for:
А
Secretion of hydrochloric acid
О
Б
Pupil size
О
В
Heart rate
О
Г
Accommodation
О
Д
Bladder tone
В
0274 A common side effect of misoprostol is:
А
Diarrhea
О
Б
Constipation
О
В
Ulceration of the gastrointestinal mucosa
О
Г
Achlorhydria
Extrapyramidal disorders (drug parkinsonism)
В
0275 with prolonged use can cause antiemetics that
block in the central nervous system:
А
Dopamine D2 receptors
О
Б
Serotonin 5-HT3 receptors
О
В
Histamine H1 receptors
О
Г
M-cholinergic receptors
В
0276
Everything is characteristic of omeprazole
except:
А
Acts shortly (appointed 4 times a day)
О
Б
Proton pump inhibitor (H +, K + -ATPase).
О
В
Is a prodrug
О
Г
Acts for a long time (appointed once a day)
О
Д
Reduces the secretion of hydrochloric acid
В
0277
For antacids, everything is characteristic
except:
А
Act for 6-8 hours.
О
Б
Taken internally
О
В
Neutralize hydrochloric acid in gastric juice
О
Г
Act for 1-2 hours.
В
0278
For laxatives containing anthraglycosides,
everything is characteristic except:
А
Effective in 4-6 hours after taking
О
Б
Effective in 8-12 hours after ingestion
О
В
Acts primarily on the large intestine
О
Г
Used for chronic constipation
О
Д
Addictive
В
0279
А
Everything is typical for loperamide, except
for:
Penetrates well into the central nervous
system
О
Б
Opioid receptor agonist
О
В
Used for diarrhea
О
Г
Inhibits intestinal peristalsis
О
Д
Poorly penetrates the central nervous system
О
Е
Does not cause drug dependence
Determine the antacid drug: it is used for
gastric ulcer and duodenal ulcer; neutralizes
В
0280 hydrochloric acid of gastric juice; possesses
adsorbent and astringent action; can cause
constipation, hypophosphatemia:
А
Aluminum hydroxide (algedrate)
О
Б
Sodium bicarbonate
О
В
Magnesium oxide
О
Г
Maalox
Determine the antacid drug: neutralizes
В
0281
hydrochloric acid of gastric juice with the
formation of CO2, acts quickly and for a short
time, can cause systemic alkalosis:
А
Sodium bicarbonate
О
Б
Aluminum hydroxide
О
В
Magnesium oxide
О
Г
Almagel
О
Д
Maalox
В
0282
А
О
Б
О
В
О
Г
О
Д
В
For bismuth tripotassium dicitrate, all of the
following is characteristic, except:
Reduces the secretion of hydrochloric acid
The effect develops in the acidic environment
of the stomach
Forms a protective layer on the ulcerative
surface
Has antimicrobial effect against Helicobacter
pylori
Assigned internally
0283 Posterior pituitary hormone drug:
А
Oxytocin
О
Б
Dinoprost
О
В
Ergotamine
О
Г
Dinoprostone
О
Д
Magnesium sulfate
О
Е
Fenoterol
В
0284
А
Magnesium sulfate belongs to the group of
drugs which:
Weaken the contractile activity of the
myometrium
Increase the contractile activity of the
О
Б
О
В
Increase the tone of the myometrium
О
Г
Does not affect myometrial contractility
В
0285
myometrium
A drug that predominantly increases the tone
of the myometrium:
А
Ergometrine
О
Б
Fenoterol
О
В
Salbutamol
О
Г
Oxytocin
О
Д
Dinoprostone
В
0286
The tocolytic effect is caused by substances
that stimulate:
А
β2-adrenergic receptors
О
Б
α-adrenergic receptors
О
В
Prostaglandin receptors
О
Г
M-cholinergic receptors
В
0287 Oxytocin is used for all indications, except for:
А
Abortion
О
Б
Stopping postpartum uterine bleeding
О
В
О
Г
Increased lactation
О
Д
Stimulation of labor
В
0288
Acceleration of uterine involution in the
postpartum period
Dinoprost and dinoprostone are used for all
indications, except for:
А
Prevention of premature birth
О
Б
Stimulation of labor
О
В
Excitation of labor
О
Г
Relaxation of the cervix
О
Д
Medical abortion
В
0289
To prevent premature birth, all of the following
drugs are used except:
А
Dinoprostone
О
Б
Salbutamol
О
В
Fenoterol
О
Г
Progesterone
Determine the drug: increases the contractile
activity of the myometrium, the effect
В
0290
increases with increasing gestational age and
is maximal during childbirth; used to stimulate
labor, with bleeding and uterine atony in the
postpartum period, to stimulate lactation:
А
Oxytocin
О
Б
Ergometrine
О
В
Dinoprostone
О
Г
Progesterone
В
0291
А
О
Б
О
В
О
Г
В
0292
The correct statement regarding the drugs
which affect the myometrium:
The tocolytic effect of hexoprenaline is due to
the stimulation of β2-adrenergic receptors
Dinoprost does not affect the tone of the
cervix
Oxytocin is an estrogenic drug
Gestagens stimulate the contractile activity of
the myometrium
The correct statement regarding drugs that
affect the myometrium:
А
Dinoprostone - Prostaglanidin E2 drug
О
Б
Atropine is a tocolytic agent
О
В
Fenoterol stimulates prostaglanidin receptors
О
Г
Salbutamol - M-anticholinergic
В
0293
Erythropoiesis-stimulating agents are all of the
following drugs, except:
А
Molgramostim
О
Б
Folic acid
О
В
Epoetin alfa
О
Г
Cyanocobalamin
О
Д
Ferrous sulfate (ferrous sulfate)
О
Е
Epoetin
В
0294
Drugs used for hypochromic anemias are all,
except:
А
Cyanocobalamin
О
Б
Tardiferron (iron II sulfate)
О
В
Ferrum Lek (iron III hydroxide polymaltose)
О
Г
Ferinject (iron III carboxymaltose)
В
0295 Drugs used for hyperchromic anemia:
А
Cyanocobalamin
О
Б
Tardiferron (iron II sulfate)
О
В
Epoetin alfa
О
Г
Molgramostim
О
Д
Filgrastim
В
0296 Leukopoiesis stimulants - all listed, except:
А
Folic acid
О
Б
Molgramostim
О
В
Filgrastim
О
Г
Sodium nucleospermate
В
0297
Molgramostim stimulates all processes, except
for:
А
Proliferation and differentiation of erythrocytes
О
Б
Granulocyte proliferation
О
В
Differentiation of granulocytes
О
Г
Proliferation of monocytes / macrophages
О
Д
Differentiation of monocytes / macrophages
О
Е
В
Functions of granulocytes and monocytes /
macrophages
0298 Filgrastim stimulates all processes except:
А
Proliferation and differentiation of lymphocytes
О
Б
Differentiation of granulocyte precursors
О
В
Proliferation of granulocyte precursors
О
Г
Chemotactic and phagocytic activity
В
0299
The main drug for the treatment of pernicious
(malignant) anemia:
А
Cyanocobalamin
О
Б
Tardiferron (iron sulfate II)
О
В
Molgramostim
О
Г
Epoetin beta
О
Д
Folic acid
В
0300
А
Molgramostim and filgrastim are used for all
indications, except for:
Macrocytic anemia
Inhibition of leukopoiesis caused by the action
О
Б
О
В
О
Г
Bone marrow transplant
О
Д
In the complex therapy of AIDS
of ionizing radiation
Inhibition of leukopoiesis caused by the use of
antitumor and immunosuppressive agents
Determine the drug that affects
hematopoiesis: is a recombinant drug of
human granulocyte-macrophage colonystimulating factor; stimulates proliferation,
В
0301
differentiation and function of granulocytes
and monocytes / macrophages; it is used in
the suppression of leukopoiesis caused by the
use of antitumor, immunosuppressive agents,
the action of ionizing radiation, in bone marrow
transplantation; administered intravenously:
А
Molgramostim
О
Б
Epoitin beta
О
В
Filgrastim
О
Г
Epoetin alfa
В
0302
Drugs that reduce platelet aggregation - all
except:
А
Bivalirudin
О
Б
Abciximab
О
В
Dipyridamole
О
Г
Clopidogrel
О
Д
Ticlopidine
О
Е
Acetylsalicylic acid
В
0303
Antiplatelet agent that inhibits thromboxane
synthesis:
А
Acetylsalicylic acid
О
Б
Dipyridamole
О
В
Heparin
О
Г
Alprostadil
О
Д
Clopidogrel
О
Е
Abciximab
В
0304
Antiplatelet agent that increases the activity of
the prostacyclin system:
А
Alprostadil
О
Б
Abciximab
О
В
Clopidogrel
О
Г
Acetylsalicylic acid
В
0305
Antiplatelet agent - blocker of glycoprotein
receptors (GP IIb / IIIa) of platelets:
А
Abciximab
О
Б
Epoprostenol
О
В
Clopidogrel
О
Г
Warfarin
В
0306
Drugs that reduce blood clotting
(anticoagulants) - everything except:
А
Protamine sulfate
О
Б
Enoxaparin
О
В
Heparin
О
Г
Warfarin
О
Д
Bivalirudin
В
0307
All of the following drugs are direct
anticoagulants except:
А
Warfarin
О
Б
Lepirudin
О
В
Heparin
О
Г
Enoxaparin
В
0308 Recombinant hirudin drug:
А
Bivalirudin
О
Б
Dabigatran
О
В
Abciximab
О
Г
Enoxaparin
О
Д
Warfarin
В
0309 Indirect anticoagulant:
А
Acenocoumarol
О
Б
Bivalirudin
О
В
Heparin
О
Г
Dabigatran
О
Д
Nadroparin calcium
В
0310 Unfractionated heparin antagonist:
А
Protamine sulfate
О
Б
Thrombin
О
В
Fibrinogen
О
Г
Aminocaproic acid
В
0311 Fibrinolytic agent:
А
Alteplaza
О
Б
Aminocaproic acid
О
В
Alprostadil
О
Г
Fibrinogen
О
Д
Acetylsalicylic acid
В
0312
All the following drugs are blood clotting
agents except:
А
Aminocaproic acid
О
Б
Fibrinogen
О
В
Menadione sodium bisulfite
О
Г
Clotting factor VII
О
Д
Thrombin
В
0313
All the following drugs prevent the formation
of blood clots except:
А
Fibrinolytic agents
О
Б
Direct anticoagulants
О
В
Indirect anticoagulants
О
Г
Antiplatelet agents
В
0314
Possible mechanisms of action of agents that
inhibit platelet aggregation are all, except:
А
Blockade of prostacyclin platelet receptors
О
Б
Blockade of platelet thromboxane receptors
О
В
О
Г
О
Д
В
0315
Decreased synthesis of thromboxane in
platelets
Blockade of glycoprotein receptors (GP IIb /
IIIa) of platelets
Blockade of platelet ADP receptors
The mechanism of antiplatelet action of
abciximab:
Blocks glycoprotein receptors (GP IIb / IIIa) of
А
platelets and prevents fibrinogen from binding
to them
Inhibits cyclooxygenase and disrupts
О
Б
О
В
Blocks thromboxane receptors in platelets
О
Г
Blocks platelet ADP receptors
В
0316
А
О
Б
О
В
О
Г
В
0317
thromboxane synthesis in platelets
The mechanism of antiplatelet action of
clopidogrel and ticlopidine:
Blocks platelet ADP receptors
Inhibit cyclooxygenase and disrupt
thromboxane synthesis in platelets
Stimulates platelet prostacyclin receptors
Block glycoprotein receptors (GP IIb / IIIa) of
platelets
All of the following drugs reduce blood
clotting, except:
А
Streptokinase
О
Б
Warfarin
О
В
Enoxaparin
О
Г
Rivaroxaban
О
Д
Heparin
В
0318
А
О
Б
О
В
О
Г
В
0319
А
All of the following is true for low-molecularweight heparins, except:
Suppress the synthesis of prothrombin in the
liver
Thrombin is not activated against the
background of drug action
Increase the inhibitory effect of antithrombin III
on the transition of prothrombin to thrombin
They have a pronounced antiplatelet effect
All of the following statements are typical for
steptokinase, except for:
Acts only in a blood clot
Causes a fibrinolytic effect by interacting with
О
Б
О
В
О
Г
Helps dissolve fresh blood clots
О
Д
Acts in blood clots and blood plasma
В
0320
plasminogen
Stimulates the transition of plasminogen to
plasmin
All of the following drugs stop bleeding by
increasing blood clotting, except:
А
Aminocaproic acid
О
Б
Fibrinogen
О
В
Thrombin
О
Г
Phytomenadione (vitamin K1)
В
0321
The synthesis of prothrombin in the liver
stimulates by:
А
Menadione sodium bisulfite
О
Б
Thrombin
О
В
Aminocaproic acid
О
Г
Warfarin
В
0322
Drug which stops bleeding by reducing the
activity of the fibrinolysis system is:
А
Aminocaproic acid
О
Б
Fibrinogen
О
В
Thrombin
О
Г
Menadione sodium bisulfite
В
0323
All of the following drugs are used to reduce
platelet aggregation except:
А
Warfarin
О
Б
Acetylsalicylic acid
О
В
Clopidogrel
О
Г
Abciximab
В
0324
Drug which is used to reduce the effects of
heparin overdose is:
А
Protamine sulfate
О
Б
Sodium hydrocitrate
О
В
Menadione sodium bisulfite
О
Г
Fondaparinux sodium
В
0325
Side effects of streptokinase are all of the
following except:
А
Thromboembolism
О
Б
Lower blood pressure
О
В
Bleeding
О
Г
Pyrogenic and allergic reactions
Determine the drug that affects the blood
coagulation system: inhibits platelet
В
0326
aggregation, prevents the formation of
thromboxane A2; used internally for the
prevention of thrombosis; can cause ulceration
of the gastrointestinal mucosa:
А
Acetylsalicylic acid
О
Б
Lepirudin
О
В
Abciximab
О
Г
Heparin
Determine the drug that affects the blood
coagulation system: prevents the interaction
В
0327 of ADP with platelet P2Y12 receptors;
antiplatelet effect develops gradually; used
internally for the prevention of thrombosis:
А
Clopidogrel
О
Б
Warfarin
О
В
Dipyridamole
О
Г
Acetylsalicylic acid
О
Д
Abciximab
Determine the drug that affects the blood
coagulation system: increases the activity of
В
0328
the prostacyclin system, stimulates
prostacyclin receptors, reduces platelet
aggregation, causes vasodilation, has a shortterm effect:
А
Alprostadil
О
Б
Clopidogrel
О
В
Acetylsalicylic acid
О
Г
Abciximab
Determine the drug that affects the blood
coagulation system: inactivates thrombin; the
В
0329 anticoagulant effect does not depend on the
activity of antithrombin III, it acts for a short
time; is a recombinant drug of hirudin:
А
Bivalirudin
О
Б
Enoxaparin
О
В
Heparin
О
Г
Dabigatran
В
0330
All of the following statements is true for
indirect anticoagulants except:
А
Administered parenterally
О
Б
Introduced inside
О
В
The effect develops slowly and lasts 2-4 days
О
Г
Only effective in vivo
О
Д
Cumulate
О
Е
May cause liver dysfunction
В
0331
Menadione sodium bisulfite is a
pharmacological antagonist of:
А
Indirect anticoagulants
О
Б
Low molecular weight heparins
О
В
Heparin
О
Г
Bivalirudin
О
Д
Dabigatran
В
0332
All of the followings match for Streptokinase,
except:
А
Anticoagulant
О
Б
Fibrinolytic agent
О
В
О
Г
О
Д
Interacts with prothrombin, stimulates its
transition to thrombin
Used to dissolve fresh blood clots
May cause bleeding due to systemic
fibrinolysis
Determine the drug that affects the blood
В
0333
coagulation system: increases blood clotting,
stimulates the transition of fibrinogen to fibrin,
is used topically to stop bleeding:
А
Thrombin
О
Б
Fibrinogen
О
В
Menadione sodium bisulfite
О
Г
Aminocaproic acid
Determine the drug that affects the blood
coagulation system: inhibits the conversion of
В
0334
prothrombin to fibrinolysin and inhibits
thrombin, administered orally and i/v; used for
bleeding associated with increased activity of
the fibrinolytic system:
А
Aminocaproic acid
О
Б
Fibrinogen
О
В
Menadione sodium bisulfite
О
Г
Thrombin
A drug that, on initial or intermittent use,
В
0335 stimulates the release of LH and FSH by the
pituitary gland:
А
Triptorelin
О
Б
Danazol
О
В
Bromocriptine
О
Г
Yodomarin
В
0336
Antithyroid drugs are all of the following drugs
except:
А
Levothyroxine sodium
О
Б
Thiamazole
О
В
Propylthiouracil
О
Г
Potassium iodide
В
0337
Antidiabetic drugs all the of following drugs
except:
А
Glucagon
О
Б
Metformin
О
В
Acarbose
О
Г
Insulin preparations
О
Д
Glibenclamide
В
0338 Biguanide antidiabetic agent:
А
Metformin
О
Б
Glibenclamide
О
В
Acarbose
О
Г
Insulin
В
0339
А
All of the following statements are true for
Levothyroxine sodium except:
Decreases basal metabolism
Activates the breakdown of proteins,
О
Б
О
В
Increases basal metabolism
О
Г
Increases tissue oxygen consumption
О
Д
Enhances the effect of adrenaline
В
0340
А
О
Б
О
В
О
Г
В
0341
А
О
Б
О
В
О
Г
О
Д
В
0342
А
carbohydrates, fats
The mechanism of thiamazole’s antithyroid
action:
Inhibition of the synthesis of thyroid hormones
in the thyroid gland
Inhibition of the production of thyroidstimulating hormone of the pituitary gland
Destruction of thyroid follicle cells
Violations of the uptake of iodine by the
thyroid gland
All of the following statements are true for
Teriparatide, except:
Reduces the content of calcium ions in the
blood
Increases the reabsorption of calcium ions in
the renal tubules
Causes decalcification of bones
Promotes the absorption of calcium ions from
the gastrointestinal tract
Increases the content of calcium ions in the
blood
Possible mechanisms of the hypoglycemic
action of metformin are all, except:
Increased insulin secretion by β-cells of the
pancreas
Facilitating the penetration of glucose into
О
Б
О
В
Decreased gluconeogenesis
О
Г
Delayed intestinal absorption of carbohydrates
В
0343
cells and its utilization
All of the following statements are typical for
metformin, except for:
А
Used for type I diabetes mellitus
О
Б
Reduces appetite and body weight
О
В
Often causes nausea and vomiting
О
Г
Assign inside
О
Д
Used for type II diabetes mellitus
В
0344
А
All statements are characteristic of acarbose
except:
Effective in type I diabetes
Reduces intestinal absorption of
О
Б
О
В
Assign inside
О
Г
Effective in type II diabetes
О
Д
Inhibits α-glucosidase
В
0345
carbohydrates
Each statement is typical for sitagliptin, except
for:
А
Inhibits α-glucosidase
О
Б
Inhibits dipeptidyl peptidase-4
О
В
Used orally
О
Г
Increases the concentration of incretins
О
Д
Increases insulin production
В
0346 Danazol is used for all indications, except for:
А
Hypogonadism
О
Б
Uterine bleeding
О
В
Endometriosis
О
Г
Gynecomastia
В
0347
For growth retardation in childhood (pituitary
dwarfism), used:
А
Somatropin
О
Б
Octreotide
О
В
Bromocriptine
В
0348
Octreotide is used for all indications, except
for:
А
Growth retardation in childhood
О
Б
Acute pancreatitis
О
В
О
Г
В
0349
To stop bleeding from varicose veins of the
esophagus
Acromegaly and gigantism
Indications for the use of oxytocin are all of the
following, except:
А
For early termination of pregnancy
О
Б
To stimulate lactation in the postpartum period
О
В
To stimulate labor
О
Г
For stopping postpartum bleeding
В
0350
The main indication for the use of
desmopressin:
А
Diabetes insipidus
О
Б
Diabetes
О
В
Acromegaly
О
Г
Weakness of labor
В
0351
For hyperthyroidism, everything is used
except:
А
Levothyroxine sodium
О
Б
Thiamazole
О
В
Propylthiouracil
О
Г
Potassium iodide
В
0352
With diabetes mellitus, all drugs are
prescribed inside, except:
А
Insulin preparations
О
Б
Sulfonylurea derivatives
О
В
Biguanides
О
Г
Acarbose
О
Д
Sitagliptin
О
Е
Rosiglitazone
В
0353 A drug which is used for diabetic coma:
А
Insulin drugs with a short latency period
О
Б
Long-acting insulin preparations
О
В
Glibenclamide
О
Г
Metformin
О
Д
Acarbose
В
0354 Nausea and vomiting often occur when using:
А
Metformin
О
Б
Acarbose
О
В
Glibenclamide
О
Г
Insulin preparations
В
0355
A decrease in appetite and body weight
causes:
А
Metformin
О
Б
Acarbose
О
В
Insulin preparations
О
Г
Glibenclamide
Determine the drug which increases the
concentration of calcium in the blood;
increases the absorption of calcium from the
В
0356 gastrointestinal tract, as well as the
reabsorption of calcium in the renal tubules;
hormonal drug promotes decalcification of
bone tissue:
А
Teriparatide
О
Б
Octreotide
О
В
Insulin
О
Г
Corticotropin
В
0357
А
The correct statement regarding hormonal
drugs is:
Desmopressin is used to treat diabetes
insipidus
О
Б
Octreotide is used for dwarf growth
О
В
Calcitonin is used for spasmophilia
О
Г
There are no correct statements
В
0358
А
Incorrect statement regarding hormonal drugs
is:
Menopausal gonadotropin in action
corresponds to luteinizing hormone
О
Б
Bromocriptine is used for galactorrhea
О
В
Calcitonin is used for osteoporosis
О
Г
Tetracosactide - analogue of corticotropin
О
Д
В
0359
Chorionic gonadotropin in action corresponds
to luteinizing hormone
Glucocorticoid drugs for resorptive action are
all the following except:
А
Flumethasone
О
Б
Dexamethasone
О
В
Triamcinolone
О
Г
Prednisolone
О
Д
Hydrocortisone
В
0360
Glucocorticoid in the form of an aerosol for
inhalation is:
А
Beclomethasone
О
Б
Flumethasone
О
В
Triamcinolone
О
Г
Prednisolone
О
Д
Dexamethasone
В
0361 Mineralocorticoid drug:
А
Desoxycorticosterone
О
Б
Flumethasone
О
В
Spironolactone
О
Г
Mifepristone
В
0362 Mineralocorticoid antagonist:
А
Spironolactone
О
Б
Mifepristone
О
В
Dexamethasone
О
Г
Tetracosactide
В
0363
А
О
Б
О
В
О
Г
В
0364
The principles of glucocorticoids action are all
listed, except:
Acts at the level of the cytoplasmic membrane
Penetrates the cell membrane, acts
intracellularly
Regulates gene transcription
Regulates the synthesis of proteins and
enzymes
Glucocorticoids cause all of the following
effects, except:
А
Lower blood glucose
О
Б
Increases blood glucose
О
В
Cause fat redistribution
О
Г
О
Д
В
Delay the excretion of sodium and water ions
from the body
Suppress protein synthesis
0365 Desoxycorticosterone affects mainly on:
А
Water-electrolyte exchange
О
Б
Protein metabolism
О
В
Carbohydrate metabolism
О
Г
Lipid metabolism
В
0366
All the following statements are true for
anabolic steroids except:
А
Reduce body weight
О
Б
Stimulates regenerative processes
О
В
Boost Protein Synthesis
О
Г
Have low androgenic activity
В
0367
Glucocorticoids are used for all indications,
except as:
А
Contraceptives
О
Б
Antiallergic drugs
О
В
Anti-shock agents
О
Г
Immunosuppressive drugs
О
Д
Anti-inflammatory drugs
В
0368
А
Indications of glucocorticoids are all of the
following except:
Bacterial infections
Inflammatory diseases of the skin and mucous
О
Б
О
В
Autoimmune diseases
О
Г
Allergic reactions of immediate type
О
Д
В
membranes
Graft rejection reactions during organ and
tissue transplantation
0369 Drugs used for autoimmune diseases are:
А
Glucocorticoids
О
Б
Estrogens
О
В
Gestagens
О
Г
Androgens
В
0370
Glucocorticoid drug used by inhalation for
bronchial asthma and allergic rhinitis:
А
Beclomethasone
О
Б
Dexamethasone
О
В
Prednisolone
О
Г
Flumethasone
В
0371
Indications for the use of anabolic steroids are
all of the following except:
А
Hirsutism
О
Б
Long-term glucocorticoid therapy
О
В
Cachexia
О
Г
Delayed callus formation in fractures
О
Д
Osteoporosis
В
0372
Drugs used to stimulate regenerative
processes are:
А
Anabolic steroids
О
Б
Glucocorticoids
О
В
Mineralocorticoids
О
Г
Gestagens
В
0373
Cyproterone is used for all indications, except
for:
А
To increase libido
О
Б
Women’s hirsutism
О
В
Acne
О
Г
Benign prostatic hyperplasia
The side effects that occur in prolonged
В
0374 therapy with prednisone are all of the
following, except:
А
Hypokalemia
О
Б
Ulceration of the gastrointestinal mucosa
О
В
Arterial hypertension
О
Г
Lowers immunity
Decreased resistance to infections, ulceration
В
0375 of the gastrointestinal mucosa, redistribution
of adipose tissue can cause all drugs, except:
А
Progesterone
О
Б
Prednisolone
О
В
Dexamethasone
О
Г
Hydrocortisone
В
0376 The masculinizing effect can be caused by:
А
Nandrolone
О
Б
Hexestrol
О
В
Progesterone
О
Г
Hydrocortisone
Determine the hormonal drug: steroid
compound; has an anti-inflammatory, antiВ
0377
allergic effect, reduces itching, is poorly
absorbed through the skin; used only topically
for inflammatory diseases of the skin and
mucous membranes:
А
Flumethasone
О
Б
Dexamethasone
О
В
Prednisolone
О
Г
Hydrocortisone
Steroid compound; has a pronounced antiallergic and anti-inflammatory effect,
В
0378 practically does not have a systemic effect;
used by inhalation for bronchial asthma and
allergic rhinitis:
А
Beclomethasone
О
Б
Flumethasone
О
В
Hydrocortisone
О
Г
Deoxycorticosterone
Determine a pharmacological group: refers to
substances of a steroid structure; enhance
В
0379
protein synthesis, increase body weight,
accelerate bone calcification; prescribed for
cachexia, osteoporosis, to stimulate
regenerative processes:
А
Anabolic steroids
О
Б
Gestagens
О
В
Glucocorticoids
О
Г
Mineralocorticoids
Determine a pharmacological group: steroid
compounds; reduce the excitability of the
myometrium, inhibit ovulation, promote the
В
0380 growth of the glandular tissue of the mammary
glands; prescribed in case of insufficiency of
the function of the corpus luteum for the
prevention of miscarriage:
А
Gestagens
О
Б
Estrogens
О
В
Mineralocorticoids
О
Г
Anabolic steroid
В
0381
Correct statements regarding hormonal drugs
are all of the following except:
А
Nandrolone - antigestagenic drug
О
Б
Prednisolone - glucocorticoid drug
О
В
Clomiphene is an antiestrogenic drug
О
Г
Finasteride is an antiandrogenic drug
В
0382 Incorrect statement regarding hormonal drugs:
А
О
Б
О
В
О
Г
В
0383
With insufficient function of the corpus
luteum, estrogens are prescribed
Glucocorticoids can cause ulceration of the
gastrointestinal mucosa
Nandrolone promotes protein synthesis
Finasteride blocks 5a-reductase and
decreases intracellular DHT levels
Disease which develops in thiamine
avitaminosis is:
А
Beriberi disease
О
Б
Scurvy
О
В
Pellagra
О
Г
Anemia
В
0384
In thiamine deficiency suffers most
pronouncedly the following system:
А
Nervous system
О
Б
Osteoarticular system
О
В
Hematopoietic system
О
Г
Genitourinary system
В
0385
In vitamin PP deficiency develops the following
desease:
А
Pellagra
О
Б
Beriberi disease
О
В
Pernicious anemia
О
Г
Scurvy
В
0386
All following effects typical for nicotinic acid
(vitamin PP), effects are characteristic, except:
А
Diuretic
О
Б
Vasodilator
О
В
Hypolipidemic
О
Г
Antipellagric
В
0387
With riboflavin deficiency, every disease
develops except:
А
Neuritis
О
Б
Angular stomatitis
О
В
Glossitis
О
Г
Vascular keratitis
О
Д
Hemeralopia
О
Е
Anaemia
В
0388
The absorption of iron drugs from the
gastrointestinal tract improves by:
А
Ascorbic acid
О
Б
Retinol
О
В
Pyridoxine
О
Г
Nicotinic acid
В
0389 Significantly affects photoreception:
А
Retinol
О
Б
Ergocalciferol
О
В
Tocopherol
О
Г
Menadione sodium bisulfite
В
0390
The synthesis of prothrombin in the liver
stimulates:
А
Menadione sodium bisulfite
О
Б
Retinol
О
В
Ergocalciferol
О
Г
Thiamine
В
0391 Ergocalciferol in the body mainly regulates:
А
Exchange of calcium and phosphorus
О
Б
Protein metabolism
О
В
Carbohydrate metabolism
О
Г
Fat metabolism
В
0392
А
О
Б
О
В
О
Г
В
Ergocalciferol is characterized by everything
except:
Decreases absorption of calcium ions from the
gastrointestinal tract
Improves absorption of calcium ions from the
gastrointestinal tract
Controls the mobilization of calcium ions from
bone tissue
Increases the reabsorption of calcium ions in
the renal tubules
0393 Wrong statement regarding vitamin drugs:
А
О
Б
О
В
О
Г
В
0394
Tocopherol reduces blood clotting
Menadione sodium bisulfite increases blood
clotting
Ergocalciferol regulates bone mineralization
In case of vitamin A deficiency, hemeralopia
develops ("night blindness")
Vitamin for the prevention and treatment of
pellagra:
А
Nicotinic acid
О
Б
Ascorbic acid
О
В
Folic acid
О
Г
Cyanocobalamin
В
0395
The main indications for the use of nicotinic
acid are everything except:
А
Gout
О
Б
Hyperlipidemia
О
В
Blood vessel spasms
О
Г
Pellagra
В
0396
With macrocytic anemia, the following drug is
prescribed:
А
Folic acid
О
Б
Nicotinic acid
О
В
Ascorbic acid
О
Г
Cyanocobalamin
В
0397 The main treatment for pernicious anemia is:
А
Cyanocobalamin
О
Б
Folic acid
О
В
Rutin
О
Г
Riboflavin
В
0398
A drug for the prevention and treatment of
scurvy:
А
Ascorbic acid
О
Б
Folic acid
О
В
Rutin
О
Г
Nicotinic acid
В
0399
Retinol is prescribed for all indications, except
for:
А
Osteomalacia
О
Б
Keratomalacia
О
В
Hemeralopia
О
Г
Xerophthalmia
О
Д
Hypekeratosis
For bleeding and hemorrhagic diathesis
В
0400 associated with hypoprothrombinemia next
vitamin is used:
А
Menadione sodium bisulfite
О
Б
Cyanocobalamin
О
В
Ascorbic acid
О
Г
Folic acid
Determine the vitamin drug: refers to watersoluble vitamins; has antianemic action; is a
В
0401
factor necessary for the normalization of
hematopoiesis and maturation of erythrocytes;
has a pronounced therapeutic effect in
pernicious anemia:
А
Cyanocobalamin
О
Б
Menadione sodium bisulfite
О
В
Ascorbic acid
О
Г
Pyridoxine
Determine the vitamin drug: refers to watersoluble vitamins; participates in the regulation
of redox processes, carbohydrate metabolism,
В
0402 tissue regeneration, the formation of steroid
hormones; normalizes vascular permeability, is
used for the prevention and treatment of
scurvy:
А
Ascorbic acid
О
Б
Nicotinic acid
О
В
Folic acid
О
Г
Rutin
Determine the vitamin drug: refers to fatsoluble vitamins, stimulates the synthesis of
В
0403 prothrombin, proconvertin and other blood
coagulation factors in the liver; is an
antagonist of indirect anticoagulants:
А
Menadione sodium bisulfite
О
Б
Retinol
О
В
Ergocalciferol
О
Г
Tocopherol
Determine the vitamin drug: refers to watersoluble vitamins; is an antipellagric agent, has
В
0404 a vasodilating and hypolipidemic effect, is
used for pellagra, atherosclerosis, vascular
spasms:
А
Nicotinic acid
О
Б
Thiamine
О
В
Rutin
О
Г
Folic acid
В
0405 Lipid-lowering drugs - all listed, except:
А
Angioprotectors
О
Б
Ezetimibe
О
В
О
Г
Fibric acid derivatives
О
Д
Nicotinic acid
В
0406
Statins (3-hydroxy-3 - methylglutaryl
coenzyme A reductase inhibitors)
Drugs that lower blood levels of triglycerides
(VLDL):
А
Fibric acid derivatives
О
Б
Statins
О
В
Ezetimibe
В
0407
An inhibitor of intestinal cholesterol
absorption:
А
Ezetimibe
О
Б
Nicotinic acid
О
В
Fluvastatin
В
0408 Statins:
А
Lovastatin
О
Б
Fenofibrate
О
В
Alirokumab
О
Г
Ezetimibe
В
0409 Antiatherogenic lipoproteins:
А
HDL
О
Б
LDPP
О
В
LDL
О
Г
VLDL
В
0410
Inhibits the transport of cholesterol in
intestinal enterocytes:
А
Ezetimibe
О
Б
Evolocumab
О
В
Lovastatin
О
Г
Nicotinic acid
В
0411 Has antioxidant activity:
А
Omega-3 triglycerides
О
Б
Nicotinic acid
О
В
Fenofibrate
О
Г
A nicotinic acid
В
0412
А
О
Б
О
В
О
Г
О
Д
В
0413
А
All of the following is typical for statins except
for:
They have an antioxidant effect
Inhibit 3-hydroxy-3-methylglutaryl coenzyme
A reductase
Suppress the synthesis of cholesterol in the
liver
Compensatory increase in the number of LDL
receptors in the liver
Decrease plasma levels of LDL
Everything is characteristic of ezetimibe
except:
Inhibits 3-hydroxy-3-methylglutaryl coenzyme
A reductase
Reduces the absorption of cholesterol in the
О
Б
О
В
Affects total cholesterol levels
О
Г
Increases the content of LDL in the liver
О
Д
Is a prodrug
В
0414
А
О
Б
О
В
О
Г
О
Д
В
0415
intestines
For derivatives of fibric acid, everything is
characteristic except:
Inhibits 3-hydroxy-3-methylglutaryl coenzyme
A reductase
Increases the activity of vascular endothelial
lipoprotein lipase
Inhibits the synthesis of VLDL in the liver
Increases the number of LDL receptors in the
liver
Stimulates endocytosis of LDL in the liver
All groups of drugs can cause myopathy,
except for:
А
Omega-3 triglycerides
О
Б
Nicotinic acid
О
В
Fibrates
О
Г
Statins
В
0416 Nicotinic acid side effects are all except:
А
Hypouricemia
О
Б
Dyspeptic disorders
О
В
Peptic ulcer of the stomach
О
Г
Hyperemia of the skin
О
Д
Hyperuricemia
О
Е
Liver dysfunction
В
0417
Fibric acid derivatives side effects are all
except:
А
Hyperemia of the skin
О
Б
Myopathy
О
В
Cholesterol gallstones
О
Г
Arrhythmias
О
Д
Dyspeptic disorders
В
0418 Lovastatin side effects are everything except:
А
Myasthenia gravis
О
Б
Myopathy
О
В
Rhabdomyolysis
О
Г
Liver dysfunction
В
0419 Ezetimibe side effects are everything except:
А
Hypotension
О
Б
Diarrhea
О
В
Nausea
О
Г
Vomiting
It inhibits the synthesis of cholesterol in the
liver, inhibiting 3-hydroxy-3-methylglutaryl
В
0420
coenzyme A reductase, compensatory
increases the number of LDL receptors, and
mainly reduces the level of LDL in the blood
plasma:
А
Lovastatin
О
Б
Ezetimibe
О
В
Omega-3 triglycerides
О
Г
Fenofibrate
Determine the drug: reduces the content of
LDL and HDL in blood plasma; reduces the
В
0421 oxidation of LDL and their atherogenicity;
almost no effect on the level of triglyceridecontaining lipoproteins:
А
Antioxidants
О
Б
Nicotinic acid
О
В
Lovastatin
О
Г
Cholestyramine
Determine the drug: reduces the activity of
intracellular lipase; reduces the content of
fatty acids in the blood and their supply to the
В
0422 liver, reduces the biosynthesis of triglycerides
and VLDL; reduces the content of LDL and
VLDL in the blood; used for all types of
hyperlipoproteinemia:
А
Nicotinic acid
О
Б
Fluvastatin
О
В
Pravastatin
О
Г
Fenofibrate
О
Д
Ezetimibe
Determine the drug: reduces the absorption of
cholesterol in the intestine by the cholesterol
В
0423 transport inhibiting in enterocytes; reduces the
content of LDL in the blood and slightly VLDL,
slightly increases the amount of HDL:
А
Ezetimibe
О
Б
Pravastatin
О
В
Gemfibrozil
О
Г
Nicotinic acid
О
Д
Atorvastatin
В
0424
А
О
Б
О
В
О
Г
В
0425
All statements regarding hyperlipidemic drugs
are true, except:
Ezetimibe - bile acid sequestrant
Nicotinic acid is used for all types of
hyperlipoproteinemia
Lovastatin reduces mainly the content of LDL
in blood plasma
Fenofibrate reduces mainly the content of
VLDL in blood plasma
All statements regarding hyperlipidemic drugs
are true, except:
А
Nicotinic acid is a statin
О
Б
Fenofibrate - a fibric acid derivative
О
В
О
Г
В
0426
Ezetimibe inhibits intestinal absorption of
cholesterol
Antioxidants reduce LDL oxidation and
atherogenicity
A drug that interferes with the absorption of
fats in the intestine:
А
Orlistat
О
Б
Sibutramine
О
В
Olestra
О
Г
Fepranon
В
0427 Everything is typical for Orlistat, except for:
А
Suppresses appetite
О
Б
Lipase inhibitor
О
В
Prevents hydrolysis of fats
О
Г
Disrupts intestinal fat absorption
Determine the drug used for obesity: inhibits
the reuptake of norepinephrine and serotonin
В
0428
in the structures of the hypothalamus that
regulate food intake; reduces appetite;
favorably affects the content of lipids in blood
plasma, can have a psychostimulating effect
А
Sibutramine
О
Б
Fepranon
О
В
Orlistat
О
Г
Olestra
Determine the drug used for obesity: does not
affect appetite; inhibits lipase and prevents the
В
0429 hydrolysis of edible fats; reduces the
absorption of cholesterol and triglycerides in
the intestine:
А
Orlistat
О
Б
Fepranon
О
В
Olestra
О
Г
Sibutramine
В
0430
Correct statement regarding remedies used
for obesity:
А
Olestra - fat substitute
О
Б
Orlistat - anorexigenic agent
О
В
Sibutramine - lipase inhibitor
О
Г
Fepranon - sugar substitute
В
0431 Sibutramine side effects are all except:
А
Bradycardia and lower blood pressure
О
Б
Insomnia
О
В
Tachycardia and increased blood pressure
О
Г
Dry mouth
В
0432
Hormones that have a beneficial effect on
osteoporosis are all except:
А
Gestagens
О
Б
Androgens
О
В
Estrogens
О
Г
Calcitonin
В
0433
Drugs that have a beneficial effect on
osteoporosis - everything except:
А
Loop diuretics
О
Б
Bisphosphonates
О
В
О
Г
В
Active metabolites and derivatives of vitamin
D3
Calcium salt preparations
0434 The drug which is a fluoride:
А
Sodium monofluorophosphate
О
Б
Alendronate
О
В
Alfacalcidol
О
Г
Phenabolin
В
0435 Everything is true for bisphosphonates except:
А
Increase the absorption of calcium ions in the
intestine
Decrease the activity and number of
О
Б
О
В
О
Г
Reduce bone resorption
О
Д
May cause osteomalacia
В
osteoclasts
Reduces the stimulating effect of osteoblasts
on osteclasts
0436 Alfacalcidol does not correspond to:
А
Calcium preparations
О
Б
Vitamin D3 derivatives
О
В
Promotes intestinal absorption of calcium
О
Г
О
Д
В
Increases calcium resorption in the renal
tubules
Can be used for hypoparathyroidism
0437 Miacalcic is not used for:
А
Hypoparathyroidism
О
Б
Nephrocalcinosis
О
В
Postmenopausal osteoporosis
О
Г
Corticosteroid osteoporosis
В
0438 The indications of alfacalciferol are all, except:
А
Hypercalcemia
О
Б
Hypocalcemia
О
В
Osteoporosis
О
Г
Hypoparathyroidism
О
Д
Rickets
В
0439 Indications of bisphosphonates are all except:
А
Hypocalcemia
О
Б
Hypercalcemia
О
В
Osteoporosis
О
Г
Hypoparathyroidism
О
Д
Osteolysis with metastases of tumors in the
bone
Determine the anti-osteoporotic drug:
increases the absorption of calcium in the
intestine and its reabsorption in the renal
В
0440 tubules; increases the content of calcium in
the blood, promotes bone mineralization; used
for hypocalcemia, hyperparathyroidism,
osteoporosis, rickets:
А
Alfacalciferol
О
Б
Alendronate
О
В
Estradiol
О
Г
Calcitrin
Determine the anti-osteoporotic drug: reduces
the content of calcium ions in the blood,
В
0441
reduces bone resorption; used for
osteoporosis and hyperparathyroidism;
requires additional administration of calcium
preparations:
А
Miacalcic
О
Б
Alendronate
О
В
Alfacalciferol
О
Г
Calcitrin
В
0442 Drugs that inhibit the biosynthesis of uric acid:
А
Allopurinol
О
Б
Colchicine
О
В
Etamide
О
Г
Indomethacin
В
0443
Anti-inflammatory drugs used for gout are all
except:
А
Allopurinol
О
Б
Prednisone
О
В
Indomethacin
О
Г
Colchicine
В
0444
Specific herbal anti-gout agent with antiinflammatory activity:
А
Colchicine
О
Б
Prednisone
О
В
Allopurinol
О
Г
Indomethacin
В
0445
Each statement is true for benzbromarone
except:
А
Has anti-inflammatory effect
О
Б
Inhibits the synthesis of purine bases
О
В
Reduces intestinal absorption of uric acid
О
Г
В
Inhibits the resorption of uric acid in the
proximal renal tubules
0446 A drug used primarily to relieve gout attacks:
А
Colchicine
О
Б
Sulfinpyrazone
О
В
Etamide
О
Г
Allopurinol
В
0447 Allopurinol side effects are all except:
А
Formation of stones in the biliary tract
О
Б
Formation of stones in the urinary tract
О
В
Dyspeptic disorders
О
Г
Inhibition of hematopoiesis
О
Д
Exacerbation of gout
В
0448
А
Long-term side effects of glucocorticoids are
all except:
Hypoglycemia
Ulceration of the mucous membrane of the
О
Б
О
В
Adrenal cortex atrophy
О
Г
Arterial hypertension
О
Д
Suppression of immunity
В
stomach and intestines
0449 Colchicine side effects are everything except:
А
Ulcerogenic action
О
Б
Severe abdominal pain
О
В
Dyspeptic disorders
О
Г
Blood Toxicity
О
Д
Alopecia
Determine the anti-gout drug: used to prevent
gout attacks; may exacerbate gout; has no
В
0450
anti-inflammatory and analgesic effect; does
not affect phospholipase A2 and
cyclooxygenase; inhibits xanthine oxidase and
uric acid biosynthesis:
А
Allopurinol
О
Б
Sulfinpyrazone
О
В
Colchicine
О
Г
Indomethacin
Determine the anti-gout drug: quickly and
effectively suppresses pain during a gout
В
0451
attack; does not affect phospholipase A2 and
cyclooxygenase; inhibits the mitotic activity of
granulocytes and their migration to the
inflammation focus:
А
Colchicine
О
Б
Allopurinol
О
В
Etamide
О
Г
Indomethacin
Determine the anti-gout drug: has a
pronounced anti-inflammatory effect; may
В
0452 cause ulcerogenic effect; It has no antipyretic
and analgesic effect, indirectly inhibits the
activity of phospholipase A2:
А
Prednisone
О
Б
Indomethacin
О
В
Kolchzin
О
Г
Etamide
Determine the anti-gout drug: used to prevent
В
0453
gout attacks; does not affect xanthine oxidase,
phospholipase A2 and cyclooxygenase; can
cause urinary tract stones:
А
Etamide
О
Б
Allopurinol
О
В
Indomethacin
О
Г
Prednisolone
В
0454
Correct statements regarding anti-gout drugs
are all except:
А
Etamide - xanthine oxidase inhibitor
О
Б
Colchicine - an alkaloid of Colchicum autumn
О
В
Indomethacin is a non-steroidal antiinflammatory drug
О
Г
О
Д
В
0455
Allopurinol - inhibits the reabsorption of uric
acid in the proximal renal tubules
Prednisolone - glucocorticoid
Glucocorticoids are all of the following drugs
except:
А
Celecoxib
О
Б
Prednisone
О
В
Dexamethasone
О
Г
Hydrocortisone
В
0456
Non-selective inhibitors of COX-1 and COX-2
are all of the following drugs except:
А
Celecoxib
О
Б
Indomethacin
О
В
Ibuprofen
О
Г
Acetylsalicylic acid
О
Д
Diclofenac
В
0457 Selective COX-2 inhibitor:
А
Celecoxib
О
Б
Naproxen
О
В
Diclofenac
О
Г
Acetylsalicylic acid
В
0458
Glucocorticoids do not interfere with the
formation of:
А
Phospholipids
О
Б
Arachidonic acid
О
В
Leukotrienes
О
Г
Prostaglandins
О
Д
Platelet activating factor
В
0459
Non-steroidal anti-inflammatory drugs inhibit
the formation of:
А
Prostaglandins
О
Б
Arachidonic acid
О
В
Platelet activating factor
О
Г
Leukotrienes
The analgesic effect of non-steroidal antiВ
0460 inflammatory drugs is due to everything
except:
О
А
By activation of opioid receptors
Б
Inhibition of the biosynthesis of prostaglandins
Decreased sensitivity of nociceptors to
О
В
inflammatory mediators (bradykinin,
histamine)
О
Г
О
Д
В
0461
Reduces the activity of macrophages and
fibroblasts
Reduces the accumulation of leukocytes
Glucocorticoids in the area of inflammation
cause everything except:
А
Increase exudation
О
Б
Constricts small vessels
О
В
Reduce exudation
О
Г
О
Д
В
0462
Reduces the activity of macrophages and
fibroblasts
Reduces the accumulation of leukocytes
The antipyretic effect is caused by all drugs
except:
А
Prednisone
О
Б
Diclofenac
О
В
Ibuprofen
О
Г
Naproxen
О
Д
Acetylsalicylic acid
В
0463
Indications for the use of non-steroidal antiinflammatory drugs are all except:
А
Cushing's syndrome
О
Б
Immediate hypersensitivity reactions
О
В
Delayed type hypersensitivity reactions
О
Г
Graft rejection reactions
О
Д
Autoimmune diseases
О
Е
Addison's disease
В
0464
Indications for the use of prednisolone are
everything except:
А
Peptic ulcer and duodenal ulcer
О
Б
Bronchial asthma
О
В
Contact dermatitis
О
Г
Autoimmune diseases
О
Д
Graft rejection reaction
В
0465
А
Non-steroidal anti-inflammatory drugs are
used for all indications except for:
As analgesics in the acute phase of myocardial
infarction
О
Б
With a gout attack
О
В
As an antipyretic agent
О
Г
For acute and chronic rheumatic diseases
О
Д
As analgesics for arthralgia, neuralgia, myalgia
В
0466
Steroidal anti-inflammatory drugs can cause
all side effects except:
А
Hypoglycemia
О
Б
Edema
О
В
Increased blood pressure
О
Г
Hypofunction of the adrenal cortex
О
Д
В
Ulceration of the mucous membrane of the
stomach and duodenum
0467 Side effects of NSAIDs are all except:
А
Suppression of adrenal function
Ulcerative lesions of the stomach and
О
Б
О
В
Dyspeptic disorders
О
Г
Allergic reactions
В
duodenum
0468 For prednisone, everything is true except:
А
Increases the release of sodium ions and water
from the body
Indirectly inhibits the activity of phospholipase
О
Б
О
В
Retains sodium and water ions in the body
О
Г
Disrupts the formation of prostaglandins
О
Д
Disrupts the formation of leukotrienes
В
A2
0469 Dexamethasone causes everything except:
А
Stimulation of immune processes
О
Б
Suppression of the formation of leukotrienes
О
В
О
Г
О
Д
Suppression of the formation of
prostaglandins
Suppression of immunity processes
Decrease in the content of lymphocytes and
eosinophils in the blood
Determine the anti-inflammatory drug:
stimulates the formation of lipocortins;
disrupts the formation of prostaglandins and
В
0470 leukotrienes due to the mediated inhibition of
the activity of phospholipase A2; has antiinflammatory and immunosuppressive
properties:
А
Prednisone
О
Б
Diclofenac
О
В
Ibuprofen
О
Г
Celecoxib
Determine the anti-inflammatory drug:
disrupts the formation of prostaglandins by
inhibiting cyclooxygenase, has antiВ
0471 inflammatory, analgesic, antipyretic and
antiplatelet properties; as side effects, it can
cause ulceration of the gastric mucosa,
bronchospasm and hearing impairment:
А
Acetylsalicylic acid
О
Б
Hydrocortisone
О
В
Diclofenac
О
Г
Prednisolone
В
0472
А
О
Б
О
В
О
Г
В
0473
А
О
Б
О
В
О
Г
В
0474
The false statement regarding antiinflammatories is:
Glucocorticoids have anti-inflammatory,
analgesic and antipyretic effects
Ibuprofen is a non-steroidal anti-inflammatory
drug
Glucocorticoids interfere with the formation of
arachidonic acid from phospholpids
Prednisolone - glucocoticoid
All statements regarding anti-inflammatory
drugs are true except:
Prednisolone has immunostimulating
properties
Acetylsalicylic acid irreversibly inhibits COX
Dexamethasone is a steroidal antiinflammatory agent
Ibuprofen has an analgesic effect
Drugs used to treat immediate allergic
reactions are all except:
А
Cytostatics
О
Б
Glucocorticoids
О
В
Histamine H1 receptor blockers
О
Г
Agents that prevent mast cell degranulation
О
Д
Adrenomimetics
Drugs that prevent the interaction of histamine
В
0475 with H1-histamine receptors in tissues are all
except:
А
Cromoline sodium
О
Б
Chloropyramine
О
В
Diphenhydramine
О
Г
Hifenadine
О
Д
Loratadin
В
0476
Drugs used in delayed-type hypersensitivity
reactions are all except:
А
Histamine H1 receptor blockers
О
Б
Cytostatics
О
В
Cyclosporine
О
Г
Steroidal anti-inflammatory drugs
В
0477 Immunosuppressants are all drugs except:
А
Non-steroidal anti-inflammatory drugs
О
Б
Cyclosporine
О
В
Glucocorticoids
О
Г
Cytostatics
Blockers of histamine H1 receptors will
В
0478 decrease all of the following effects of
histamine, except:
А
Increased gastric secretion
О
Б
Increased capillary permeability
О
В
О
Г
В
0479
А
О
Б
О
В
О
Г
В
Increasing the tone of the bronchi and
intestines
Decreased tone of smooth muscles of the
arteries
Everything is typical for Diphenhydramine
except for:
Prevents the release of allergy mediators from
mast cells
Blocks histamine H1 receptors
Used to treat immediate-type allergic
reactions
Has hypnotic properties
0480 Properties of glucocorticoids are all except:
А
Antipyretic
О
Б
Anti-inflammatory
О
В
Immunosuppressive
О
Г
Antiallergic
В
0481
The immunosuppressive effect of
glucocorticoids is due to everything except:
А
Violation of the prostanoids synthesis
О
Б
Suppression of T-lymphocytes proliferation
О
В
Decreased production of cytokines
О
Г
Suppression of cytotoxic T-lymphocytes
О
Д
Decreased activity of T-killers
В
0482 Everything is true for azathioprine, except for:
А
Suppresses the production of interleukin-2
О
Б
Inhibits Purine Synthesis
О
В
О
Г
В
In the body, it is transformed into 6mercaptopurine
Inhibits the early phase of T-lymphocyte
proliferation
0483 Everything is true about Takvitin except:
А
Used as an immunosuppressant
О
Б
Stimulates the production of cytokines
О
В
О
Г
В
Restores suppressed production of Tlymphocytes
Thymus hormone
0484 Everything is true about Takvitin except:
А
О
Б
О
В
О
Г
О
Д
В
0485
Suppresses the activity of macrophages
Stimulates aggression of interleukin-2
receptors
Increases the "killer" activity of T-lymphocytes
Stimulates the production of interleukin-1 and
interleukin-2
Used for immunodeficiency states
For immediate hypersensitivity reactions all
druvgs are used except:
А
Azathioprine
О
Б
Diphenhydramine
О
В
Prednisone
О
Г
Cromoline sodium
О
Д
Epinephrine
В
0486
Indications of H1-histamine receptors blockers
are all except:
А
Collagenoses
О
Б
Hives
О
В
Pollinosis
О
Г
Quincke's edema
О
Д
Serum sickness
В
0487
Diphenhydramine is used for all indications,
except for:
А
Anaphylactic shock
О
Б
Allergic rhinitis and conjunctivitis
О
В
Pollinosis
О
Г
As a sleeping pill
Determine the anti-allergic drug: prevents the
release of allergy mediators from mast cells;
В
0488
inhibit T-lymphocytes; have anti-inflammatory
and immunosuppressive properties; used for
hypersensitivity reactions of immediate and
delayed types:
А
Glucocorticoids
О
Б
Cytostatics
О
В
Immunostimulants
О
Г
Histamine H1 receptor blockers
Determine the drug: prevents the interaction
of histamine with H1-histamine receptors;
В
0489
weaken the ability of histamine to cause
spasm of smooth muscles of the bronchi and
intestines, increase capillary permeability;
used for immediate allergic reactions:
А
Loratadin
О
Б
Cromoline sodium
О
В
Prednisolone
О
Г
Azathioprine
Weakens the ability of histamine to increase
capillary permeability and cause spasms of the
В
0490
bronchi and intestines, but does not affect the
ability of histamine to increase gastric
secretion; has a hypnotic effect; used for
immediate allergic reactions:
А
Diphenhydramine
О
Б
Prednisolone
О
В
Aminophylline
О
Г
Cromoline sodium
Determine the drug: prevents the release of
allergy mediators from mast cells; does not
В
0491
possess adrenomimetic properties; used to
prevent attacks of bronchial asthma, with
developing attacks of bronchial asthma is
ineffective:
А
Cromoline sodium
О
Б
Aminophylline
О
В
Prednisone
О
Г
Epinephrine
Determine the drug: prevents the release of
allergy mediators from mast cells; increases
В
0492 blood pressure, dilates the bronchi, increases
blood glucose; used to relieve anaphylactic
shock and attacks of bronchial asthma:
А
Epinephrine
О
Б
Mebhydrolin
О
В
Diphenhydramine
О
Г
Cromoline sodium
О
Д
Aminophylline
Determine the drug: inhibits the proliferation of
lymphocytes and reduces their cytotoxicity,
prevents the release of allergy mediators from
В
0493
mast cells, disrupts the formation of
prostaglandins and leukotrienes; has antiinflammatory and immunosuppressive
properties; used for hypersensitivity reactions
of immediate and delayed types:
А
Prednisone
О
Б
Epinephrine
О
В
Diphenhydramine
О
Г
Cromoline sodium
О
Д
Cyclosporine
В
0494
Glucocorticoids can cause all of the following
effects except:
А
Increased immunity
О
Б
Decreased immunity
О
В
Slow down regeneration
О
Г
О
Д
В
0495
Ulcerative lesions of the stomach and
duodenum
Hypofunction of the adrenal cortex
All statements regarding antiallergic and
immunotropic agents are correct, except for:
А
Cromoline sodium - immunosuppressant
О
Б
Prednisolone - immunosuppressant
О
В
Hydrocortisone - glucocorticoid
О
Г
В
0496
А
О
Б
О
В
О
Г
В
0497
А
О
Б
О
В
О
Г
В
Diphenhydramine - histamine H1 receptor
blocker
All statements regarding antiallergic and
immunotropic agents are correct, except for:
Mebhydrolin is effective for delayed-type
allergic reactions
Cyclosporine has immunosuppressive
properties
Aminophylline is used to prevent and relieve
bronchospasm
Taktivine is effective in immunodeficient
conditions
All statements regarding antiallergic and
immunotropic agents are correct, except for:
Mebhydrolin prevents the release of allergy
mediators from mast cells
Cromoline sodium is used to prevent
bronchospasm
Epinephrine is the drug of choice for
anaphylactic shock
Aminophylline has a myotropic antispasmodic
effect
0498 Nitrofuran derivative:
А
Furacilin
О
Б
Pure phenol
О
В
Chloramine B
О
Г
Ethacridine
В
0499
О
Chlorhexidine is characterized by all of the
above, except:
А
Denatures proteins of microorganisms
Б
Has a bactericidal or bacteriostatic effect
Violates the integrity of the cell, causes
О
В
precipitation of the cytoplasmic contents of
bacteria
It is used to treat hands and infected wound
О
Г
surfaces, diseases of the oral cavity and
pharynx.
В
0500
А
Correct statements regarding antiseptics are
all except:
Formaldehyde is used for rinsing
Potassium permanganate in the presence of
О
Б
О
В
Benzalkonium chloride belongs to detergents
О
Г
Furacilin (nitrofural) - a nitrofuran derivative
В
0501
А
О
Б
О
В
О
Г
organic compounds releases atomic oxygen
Correct statements regarding antiseptics are
all except:
Phenol solutions are used to treat skin and
mucous membranes
Methylene blue is used for cyanide poisoning
Ammonia solution is used to treat the
surgeon's hands
Brilliant green is used for purulent skin lesions
В
0502 β-Lactam antibiotics - all except:
А
Azalids
О
Б
Penicillins
О
В
Cephalosporins
О
Г
Monobactams
О
Д
Carbapenems
В
0503 Azalides include:
А
Azithromycin
О
Б
Benzathine benzylpenicillin
О
В
Oxacillin
О
Г
Cefpirome
О
Д
Vancomycin
О
Е
Clindamycin
О
Ж
Erythromycin
В
0504 Tetracyclines group antibiotic is:
А
Doxycycline
О
Б
Azithromycin
О
В
Clindamycin
О
Г
Cefotaxime
О
Д
Vancomycin
В
0505 Polypeptide antibiotic:
А
Polymyxin B
О
Б
Azithromycin
О
В
Vancomycin
О
Г
Imipenem
О
Д
Aztreons
О
Е
Clindamycin
О
Ж
Erythromycin
В
0506 Lincosamide:
А
Clindamycin
О
Б
Meropenem
О
В
Cephalexin
О
Г
Erythromycin
О
Д
Vancomycin
О
Е
Amikacin
В
0507
Mostly gram-negative bacteria are affected
by:
А
Polymyxin B
О
Б
Amikacin
О
В
Tetracycline
О
Г
Vancomycin
О
Д
Clindamycin
О
Е
Benzylpenicillin novocaine salt
В
0508 Active against Pseudomonas aeruginosa:
А
Gentamicin
О
Б
Oxacillin
О
В
Benzylpenicillin novocaine salt
О
Г
Benzathine benzylpenicillin
В
0509
Protein synthesis on ribosomes is disrupted by
all groups of antibiotics, except for:
А
Rifampicin
О
Б
Aminoglycosides
О
В
Erythromycin
О
Г
Chloramphenicol
О
Д
Tetracyclines
О
Е
Vancomycin
В
0510 Rifampicin disrupts:
А
RNA synthesis
О
Б
Protein synthesis on ribosomes
О
В
Permeability of the cytoplasmic membrane
О
Г
Cell wall synthesis
В
0511 Polymyxin B interferes with:
А
Permeability of the cytoplasmic membrane
О
Б
RNA synthesis
О
В
Cell wall synthesis
О
Г
Protein synthesis on ribosomes
В
0512
β-Lactam antibiotics are bactericidal because
they disrupt:
А
Cell wall synthesis
О
Б
Protein synthesis on ribosomes
О
В
Permeability of the cytoplasmic membrane
О
Г
RNA synthesis
В
0513
Biosynthetic penicillins act bactericidal
because they disrupt:
А
Cell wall synthesis
О
Б
RNA synthesis
О
В
Permeability of the cytoplasmic membrane
О
Г
Protein synthesis on ribosomes
В
0514
Semisynthetic penicillins act bactericidal
because they disrupt:
А
Cell wall synthesis
О
Б
Protein synthesis on ribosomes
О
В
Permeability of the cytoplasmic membrane
О
Г
RNA synthesis
В
0515
Carbapenems act bactericidal because they
disrupt:
А
Cell wall synthesis
О
Б
Protein synthesis on ribosomes
О
В
Permeability of the cytoplasmic membrane
О
Г
RNA synthesis
В
0516
Aztreonam acts bactericidal because it
disrupts:
А
Cell wall synthesis
О
Б
Permeability of the cytoplasmic membrane
О
В
RNA synthesis
О
Г
Protein synthesis on ribosomes
В
0517
Tetracyclines act bacteriostatically because
they disrupt:
А
Protein synthesis on ribosomes
О
Б
Permeability of the cytoplasmic membrane
О
В
RNA synthesis
О
Г
Cell wall synthesis
В
0518
Polymyxin B acts bactericidal because it
disrupts:
А
Permeability of the cytoplasmic membrane
О
Б
Protein synthesis on ribosomes
О
В
Cell wall synthesis
О
Г
RNA synthesis
В
0519 Rifampicin is bactericidal because it disrupts:
А
RNA synthesis
О
Б
Permeability of the cytoplasmic membrane
О
В
Protein synthesis on ribosomes
О
Г
Cell wall synthesis
В
0520
Chloramphenicol acts bacteriostatically
because it disrupts:
А
Protein synthesis on ribosomes
О
Б
Permeability of the cytoplasmic membrane
О
В
Cell wall synthesis
О
Г
RNA synthesis
В
0521
Glycopeptides act bactericidal because they
disrupt:
А
Cell wall synthesis
О
Б
Permeability of the cytoplasmic membrane
О
В
Protein synthesis on ribosomes
О
Г
RNA synthesis
В
0522
Erythromycin acts bacteriostatically because it
disrupts:
А
Protein synthesis on ribosomes
О
Б
Cell wall synthesis
О
В
Permeability of the cytoplasmic membrane
О
Г
RNA synthesis
В
0523
А
All microorganisms are sensitive to
biosynthetic penicillins, except:
Β-lactamase-producing gram-positive cocci
Gram-positive cocci that do not produce β-
О
Б
О
В
Gram-negative cocci
О
Г
Causative agents of gas gangrene and tetanus
О
Д
Diphtheria bacillus
О
Е
The causative agent of anthrax
В
0524
А
lactamase
All microorganisms are sensitive to ampicillin,
except:
Β-lactamase-producing gram-positive cocci
Gram-positive cocci that do not produce β-
О
Б
О
В
Gram-negative cocci
О
Г
Causative agents of gas gangrene and tetanus
О
Д
Diphtheria bacillus
О
Е
О
Ж
В
0525
lactamase
Intestinal group of bacteria (shigella,
salmonella)
Chlamydia
Semisynthetic penicillin with the highest
activity against Pseudomonas aeruginosa:
А
Carbenicillin
О
Б
Oxacillin
О
В
Amoxicillin
О
Г
Ampicillin
В
0526 Cephalosporins:
А
Have a wide spectrum of action
О
Б
Affect mainly gram-positive bacteria
О
В
Effective against chlamydia
О
Г
Affects mainly gram-negative bacteria
В
0527 Carbapenems:
А
Have a wide spectrum of action
О
Б
Affect mainly gram-positive bacteria
О
В
Effective against chlamydia
О
Г
Affects mainly gram-negative bacteria
В
0528 Aztreonam:
А
Affects mainly gram-negative bacteria
О
Б
Affects mainly gram-positive bacteria
О
В
Effective against chlamydia
О
Г
Has a broad spectrum of action
В
0529 The most sensitive to erythromycin are:
А
Gram-positive cocci, spirochetes and borrelia
О
Б
Gram-negative cocci
О
В
Chlamydia
О
Г
В
0530
Intestinal group of bacteria (shigella,
salmonella)
All microorganisms are sensitive to
tetracyclines, except:
А
Mycobacterium tuberculosis
О
Б
Ricketsia
О
В
О
Г
О
Д
О
Е
В
Intestinal group of bacteria (shigella,
salmonella)
Cholera vibrio
Causative agents of plague, brucellosis,
tularemia
Gram-positive and gram-negative cocci
0531 Sensitive to polymyxin B:
А
Pseudomonas aeruginosa
О
Б
Mycobacterium tuberculosis
О
В
Gram-positive cocci
О
Г
О
Д
В
0532
А
О
Б
О
В
О
Г
О
Д
В
0533
Intestinal group of bacteria (shigella,
salmonella)
Causative agents of gas gangrene and tetanus
All of the following is true for carbenicillin,
except
Affects mainly gram-positive flora
Active against Pseudomonas aeruginosa and
all types of proteus
Has a broad spectrum of action
It breaks down in the acidic environment of the
stomach
Administered parenterally
Semisynthetic penicillin which is resistant to βlactamases of gram-positive bacteria:
А
Oxacillin
О
Б
Amoxicillin
О
В
Azlocillin
О
Г
Ampicillin
О
Д
Carbenicillin
В
0534 Erythromycin:
А
Acts bacteriostatically
О
Б
Affects mainly gram-negative bacteria
О
В
Has a broad spectrum of action
О
Г
Acts bactericidal
Determine the drug: Acts mainly on grampositive bacteria; disrupt the synthesis of the
В
0535
cell wall; not resistant to β-lactamases of
gram-positive bacteria; destroyed in the acidic
environment of the stomach; are prescribed
parenterally:
А
Biosynthetic penicillins
О
Б
Tetracyclines
О
В
Cephalosporins
О
Г
Macrolides
Determine the drug: acts mainly on grampositive bacteria; disrupt the synthesis of the
cell wall; resistant to β-lactamases of gramВ
0536 positive bacteria; do not act on spirochetes
and borellias; acid resistant; administered
orally and parenterally; duration of action 4-6
hours:
А
Oxacillin
О
Б
Amoxicillin
О
В
Erythromycin
О
Г
Benzylpenicillin sodium salt
О
Д
Ampicillin
Determine the drug: has a wide spectrum of
action; disrupts the synthesis of the cell wall is
В
0537 unstable to β-lactamases of gram-positive
bacteria; acid-fast, administered orally and
parenterally; duration of action 4-8 hours:
А
Ampicillin
О
Б
Amoxicillin
О
В
Oxacillin
О
Г
Benzylpenicillin sodium salt
Determine the drug: the spectrum of action is
close to the sodium salt of benzylpenicillin;
В
0538 disrupts protein synthesis on ribosomes; able
to accumulate in phagocytes; appoint inside;
duration of action 4-6 hours:
А
Erythromycin
О
Б
Oxacillin
О
В
Ampicillin
О
Г
Gentamicin
Determine the drug: has a wide spectrum of
action; is highly effective against the causative
agents of plague, tularemia, brucellosis,
В
0539
cholera, as well as rickettsia, chlamydia; in
terms of influence on gram-positive bacteria,
they are inferior to benzylpenicillin
preparations; disrupt protein synthesis on
ribosomes; deposited in bones:
А
Tetracyclines
О
Б
Cephalosporins
О
В
Aminoglycosides
О
Г
Lincosamides
Determine the drug: has a wide spectrum of
action; is effective against mycobacterium
tuberculosis, Pseudomonas aeruginosa;
В
0540 disrupts protein synthesis on ribosomes; has a
bactericidal effect; poorly absorbed from the
digestive tract; bacterial resistance develops
slowly; are prescribed parenterally:
А
Gentamicin
О
Б
Tetracyclines
О
В
Erythromycin
Determine the drug: acts mainly on gramnegative bacteria; is effective against
Pseudomonas aeruginosa; violates the
В
0541 permeability of the cytoplasmic membrane;
poorly absorbed from the digestive tract;
bacterial resistance develops slowly; are
prescribed parenterally:
А
Polymyxin B
О
Б
Chloramphenicol
О
В
Tetracycline
О
Г
Gentamicin
Determine the drug: acts mainly on
streptococci and staphylococci, bacterioids;
В
0542 disrupts protein synthesis on ribosomes; has a
bacteriostatic effect, is well absorbed from the
gastrointestinal tract; appoint inside:
А
Clindamycin
О
Б
Erythromycin
О
В
Tetracycline
О
Г
Oxacillin
For staphylococcal infections, resistance to
В
0543 biosynthetic penicillins, all drugs are used,
except
А
Ampicillin
О
Б
Oxacillin
О
В
Vancomycin
О
Г
Macrolides
О
Д
Cephalosporins
The drugs of choice for the treatment of
В
0544 infections caused by Pseudomonas
aeruginosa - everything except:
А
Tetracyclines
О
Б
Azlocillin
О
В
Aminoglycosides
О
Г
Carbenicillin
В
0545 As an anti-tuberculosis drug used:
А
Streptomycin
О
Б
Tetracycline
О
В
Ampicillin
О
Г
Erythromycin
В
0546
The antibiotics for treatment of infections
caused by streptococci are all except:
А
Macrolides
О
Б
Aminoglycosides
О
В
Biosynthetic penicillins
О
Г
Ampicillin
В
0547
Side effects associated with the
chemotherapeutic effect of antibiotics:
А
Aggravation reaction
О
Б
Liver damage
О
В
Kidney damage
О
Г
Allergic reactions
В
0548
The side effects of biosynthetic penicillins are
all except:
А
Hearing loss and vestibular disorders
О
Б
Allergic reactions
О
В
Local irritant action
О
Г
Aggravation reaction
В
0549 Ampicillin side effects are all except:
А
Liver damage
О
Б
Allergic reactions
О
В
Dysbacteriosis
О
Г
Aggravation reaction
В
0550
The side effects of cephalosporins are all
except:
А
Hearing impairment and vestibular disorders
О
Б
Aggravation reaction
О
В
Dysbacteriosis
О
Г
Allergic reactions
В
0551 The side effects of erythromycin are all except:
А
Kidney damage
О
Б
Liver damage
О
В
Allergic reactions
О
Г
Dysbacteriosis
В
О
0552 Side effects of tetracyclines are all except:
А
Kidney damage
Б
Allergic reactions
О
В
Liver damage
О
Г
Dysbacteriosis
О
Д
Photosensitization
О
Е
Impaired skeletal formation
В
0553 Chloramphenicol side effects are all except:
А
Liver damage
О
Б
Dysbacteriosis
О
В
Inhibition of hematopoiesis
О
Г
Allergic reactions
В
0554 Side effects of aminoglycosides are all except:
А
Liver damage
О
Б
Allergic reactions
О
В
Aggravation reaction
О
Г
Kidney damage
О
Д
Hearing and vestibular system impairment
О
Е
Blockade of neuromuscular transmission
В
0555 Side effects of clindamycin are all except:
А
Kidney damage
Dysbacteriosis (pseudomembranous colitis,
О
Б
О
В
Allergic reactions
О
Г
Leukopenia
О
Д
Liver damage
В
etc.)
0556 Side effects of vancomycin are all except:
А
Liver damage
О
Б
Allergic reactions
О
В
Kidney damage
О
Г
Local irritant action
О
Д
Hearing impairment
О
Е
Inhibition of hematopoiesis
В
0557 All drugs can cause liver damage except:
А
Aminoglycosides
О
Б
Tetracyclines
О
В
Rifampicin
О
Г
Erythromycin
В
0558 Ototoxic action is caused by:
А
Aminoglycosides
О
Б
Macrolides
О
В
Polymyxin B
О
Г
Rifampicin
В
0559
A depressing effect on neuromuscular
transmission is caused by:
А
Aminoglycosides
О
Б
Biosynthetic penicillins
О
В
Rifampicin
О
Г
Tetracyclines
В
0560 Rational combination of antibiotics
А
Ampicillin + Oxacillin
Benzylpenicillin sodium salt (benzylpenicillin)
О
Б
О
В
Polymyxin M + streptomycin
О
Г
Streptomycin + amikacin
В
+ tetracycline
0561 Everything is true regarding antibiotics except:
А
Erythromycin disrupts the permeability of the
cytoplasmic membrane
О
Б
Ampicillin disrupts cell wall synthesis
О
В
Doxycycline has a broad spectrum of action
О
Г
В
О
Б
О
В
О
Г
О
Б
О
В
О
Г
О
Б
О
В
О
Г
Chloramphenicol has a broad spectrum of
action
Amoxicillin is administered orally
Bacterial resistance to gentamicin develops
slowly
Tetracycline disrupts the permeability of the
cytoplasmic membrane
Aminoglycosides disrupt protein synthesis on
ribosomes
Rifampicin disrupts RNA synthesis
Cephalosporins interfere with cell wall
synthesis
Benzylpenicillin sodium salt is a semisynthetic penicillin
Azlocillin is effective against Pseudomonas
aeruginosa
Polymyxin B is neurotoxic
Clavulanic acid expands the spectrum of
antibacterial action of amoxicillin
0565 The correct statement regarding antibiotics is:
А
О
Б
О
В
О
Г
В
positive bacteria
0564 Everything is true regarding antibiotics except:
А
В
Oxacillin is destroyed by β-lactamase of gram-
0563 Everything is true regarding antibiotics except:
А
В
bacteria
0562 Everything is true regarding antibiotics except:
А
В
Streptomycin does not affect anaerobic
Aminoglycosides can cause hearing damage
and vestibular disorders
Oxacillin has a broad spectrum of action
Bacterial resistance to erythromycin develops
slowly
Bicillins are stable in the acidic environment of
the stomach
0566 Everything is true regarding antibiotics except:
А
Aztreonam acts bacteriostatically
Imipenem is destroyed by dihydropeptidase-1
О
Б
О
В
Tetracycline is deposited in bone tissue
О
Г
Cephalosporins are broad-spectrum
В
of the proximal renal tubules
0567 Everything is true regarding antibiotics except:
А
Vancomycin acts bacteriostatically
О
Б
Clindamycin is effective against bacterioids
О
В
О
Г
В
Polymyxin B disrupts the permeability of the
cytoplasmic membrane
Cefotaxime is administered parenterally
0568 Everything is true regarding antibiotics except:
А
О
Б
О
В
О
Г
В
0569
Cefaclor is destroyed in the acidic environment
of the stomach
Tetracyclines are the drugs of choice for
cholera, plague, brucellosis
Aminoglycosides are nephrotoxic
Vancomycin is used for infections caused by
multidrug-resistant staphylococcal strains
For resorptive action, all sulfonamides are
used, except:
А
Phthalylsulfathiazole
О
Б
Sulfadimidine
О
В
Sulfalen
О
Г
Sulfadimethoxine
В
0570 Sulfanilamide which works for 4-6 hours:
А
Sulfadimidine
О
Б
Sulfaguanidine
О
В
Phthalylsulfathiazole
О
Г
Sulfalen
В
0571 Ultra-long-acting sulfanilamide drug:
А
Sulfalen
О
Б
Phthalylsulfathiazole
О
В
Sulfadimethoxine
О
Г
Sulfacetamide
В
0572 Mainly in the intestinal lumen acts:
А
Phthalylsulfathiazole
О
Б
Sulfalen
О
В
Sulfadimethoxine
О
Г
Sulfadimidine
В
0573 Sulfanilamide drugs:
А
Have a wide spectrum of action
О
Б
Affect mainly gram-positive bacteria
О
В
Affects mainly gram-negative bacteria
О
Г
Effective against mycobacteria
В
0574
Sulfanilamide drugs affect all microorganisms
except:
А
Mycobacterium tuberculosis
О
Б
Clostridia
О
В
Gram-positive and gram-negative cocci
О
Г
Shigella
О
Д
Chlamydia
О
Е
Bacterioids
В
0575 Sulfanilamide drugs disrupt:
А
Nucleic acid synthesis
О
Б
Protein synthesis on ribosomes
О
В
Cell wall synthesis
О
Г
Permeability of the cytoplasmic membrane
В
0576 Trimethoprim disrupts
А
Nucleic acid synthesis
О
Б
Permeability of the cytoplasmic membrane
О
В
Cell wall synthesis
О
Г
Protein synthesis
В
0577
All sulfonamides are well absorbed from the
gastrointestinal tract except:
А
Phthalylsulfathiazole
О
Б
Sulfadimidine
О
В
Sulfadimethoxine
О
Г
Sulfalen
О
Д
Sulfacetamide
Determine the sulfa drug: well absorbed from
В
0578 the gastrointestinal tract; appoint 4-6 times a
day:
А
Sulfadimidine
О
Б
Phthalylsulfathiazole
О
В
Sulfadimethoxine
О
Г
Sulfalen
Determine the sulfa drug: poorly absorbed
from the gastrointestinal tract; the
В
0579 antimicrobial effect is due to the formation of
norsulfazole; used to treat intestinal infections;
used 4-6 times a day:
А
Phthalylsulfathiazole
О
Б
Sulfadimidine
О
В
Sulfalen
О
Г
Sulfadimethoxine
Determine the sulfa drug: well absorbed from
В
0580
the gastrointestinal tract; effectively
reabsorbed in the kidneys; binds to blood
proteins by 80-85%; used 1-2 times a day:
А
Sulfadimethoxine
О
Б
Phthalylsulfathiazole
О
В
Sulfadimidine
О
Г
Sulfalen
В
0581
For the prevention and treatment of bacterial
conjunctivitis, the following drug is used:
А
Sulfacetamide
О
Б
Sulfadimidine
О
В
Sulfadimethoxine
О
Г
Phthalylsulfathiazole
В
0582 Sulfasalazine is used for:
А
Ulcerative colitis and Crohn's disease
О
Б
Intestinal infections
О
В
Infectious eye lesions
О
Г
Soft tissue infections
В
0583 Side effects of sulfa drugs are all listed except:
А
Aggravation reaction
О
Б
Allergic reactions
О
В
Dysbacteriosis
О
Г
Crystalluria
О
Д
Hematological disorders (anemia, leukopenia)
О
Е
Dyspeptic symptoms
В
0584 Rational combinations are all except:
А
Sulfonamides + folic acid
О
Б
Sulfonamides + tetracyclines
О
В
Sulfonamides + chloramphenicol
О
Г
Sulfonamides + trimethoprim
В
0585 Correct statement regarding sulfonamides:
А
Sulfadimidine is prescribed 4-6 times a day
О
Б
Sulfadimethokine is not renal reabsorbed
О
В
О
Г
В
0586
А
Sulfadimidine is poorly absorbed from the
gastrointestinal tract
Phthalylsulfathiazole is well absorbed from the
gastrointestinal tract
Everything is true regarding sulfonamides
except:
Sulfadimethoxine is prescribed 4-6 times a
day
Phthalylsulfathiazole is used for intestinal
О
Б
О
В
Sulfadimidine has a broad spectrum of action
О
Г
Silver sulfathiazole is used externally
В
0587
infections
Everything is true regarding sulfonamides
except:
А
Trimethoprim has a bactericidal effect
О
Б
Sulfadimidine has a bacteriostatic effect
О
В
О
Г
В
0588
Co-trimoxazole is more effective than sulfa
drugs
Sulfadimethoxine causes crystalluria
Everything is true regarding sulfonamides
except:
А
Sulfalene is prescribed 1-2 times a day.
О
Б
Silver sulfathiazole is used topically
О
В
Sulfanilamide drugs cause allergic reactions
О
Г
Co-trimoxazole has a bactericidal effect
В
0589 Quinolone derivatives are all except:
А
Nitroxoline
О
Б
Nalidixic acid
О
В
Ofloxacin
О
Г
Ciprofloxacin
О
Д
Moxifloxcin
В
0590 Fluoroquinolones are all except:
А
Nitroxoline
О
Б
Ofloxacin
О
В
Ciprofloxacin
О
Г
Moxifloxacin
В
0591 8-hydroxyquinoline derivative:
А
Nitroxoline
О
Б
Furazolidone
О
В
Nalidixic acid
О
Г
Metronidazole
В
0592 Oxazolidinones:
А
Linezolid
О
Б
Dioxidine
О
В
Metronidazole
О
Г
Ciprofloxacin
В
0593 Nalidixic acid disrupts:
А
DNA synthesis
О
Б
Protein synthesis on ribosomes
О
В
Permeability of the cytoplasmic membrane
О
Г
Cell wall synthesis
В
0594 Linezolid disrupts:
А
Protein synthesis on ribosomes
О
Б
Permeability of the cytoplasmic membrane
О
В
Cell wall synthesis
О
Г
DNA replication
О
Д
RNA formation
В
0595 All drugs have a bactericidal effect, except for:
А
Nitroxoline
О
Б
Nitrofurans
О
В
Quinolone derivatives
О
Г
Quinoxaline derivatives
О
Д
Linezolid
В
0596 Everything is true about nalidixic acid except:
А
Has a broad spectrum of action
О
Б
Affects mainly gram-negative bacteria
О
В
Acts bactericidal
О
Г
Well absorbed from the gastrointestinal tract
О
Д
Excreted by the kidneys, mainly unchanged
О
Е
Bacterial resistance develops rapidly
В
0597
For fluoroquinolones everything is typical
except:
А
Affect mainly gram-positive bacteria
О
Б
Have a wide spectrum of action
О
В
О
Г
Disrupt DNA replication and RNA formation
О
Д
They act bactericidal
О
Е
Bacterial resistance develops slowly
В
Inhibit topoisomerase II and topoisomerase IV
in a microbial cell
0598 Everything is true about ciprofloxacin except:
А
Does not penetrate the blood-brain barrier
Highly effective against gonococci,
О
Б
О
В
О
Г
Penetrates the blood-brain barrier
О
Д
Has a broad spectrum of action
О
Е
For oral and intravenous administration
О
Ж
Assign 2 times a day
В
0599
Escherichia coli, Shigella, Salmonella
Active against Pseudomonas aeruginosa,
mycoplasma, chlamydia, klebsiella
For urinary tract infections everything is used
except:
А
Furazolidone
О
Б
Fluoroquinolones
О
В
Nitroxoline
О
Г
Furadonin (nitrofurantoin)
О
Д
Nalidixic acid
В
0600
Furazolidone is used for all infections, except
for:
А
Amoebic dysentery
О
Б
Bacillary dysentery
О
В
Giardiasis
О
Г
Trichomoniasis
В
0601 Nitroxoline is used for:
А
Urinary tract infections
О
Б
Respiratory system infections
О
В
CNS infections
О
Г
Skin and soft tissue infections
В
0602
Nalidixic acid can cause all of the listed side
effects, except:
А
Hearing loss and vestibular disorders
О
Б
Dyspeptic disorders
О
В
Photosensitization
О
Г
Visual impairment
О
Д
Allergic reactions
В
0603
Fluoroquinolones can cause all of the listed
side effects except:
А
Hearing loss and vestibular disorders
О
Б
Dysbacteriosis
О
В
Dyspeptic disorders
О
Г
Insomnia
О
Д
Photosensitization
О
Е
Allergic reactions
В
0604
Furazolidone can cause all of the listed side
effects except:
А
Photosensitization
О
Б
Dyspeptic disorders
О
В
Allergic reactions
О
Г
О
Д
О
Е
Teturam-like effect when combined with ethyl
alcohol
Anorexia
Hematological disorders (leukopenia and
anemia)
В
0605
Linezolid can cause all of the listed side
effects except:
А
Kidney damage
О
Б
Allergic reactions
О
В
Dyspeptic disorders
О
Г
Dysbacteriosis
О
Д
В
0606
Hematologic disorders (anemia and
thromocytopenia)
Correct statements regarding antimicrobial
agents are all except:
А
Nalidixic acid has a bacteriostatic effect
О
Б
Furazolidone is effective for giardiasis
О
В
Ciprofloxacin has a broad spectrum of action
О
Г
Linezolid is a synthetic antibacterial agent
В
0607
А
О
Б
Correct statements regarding antimicrobial
agents are all except:
Ofloxacin does not cross the blood-brain
barrier
Dioxidine has a broad spectrum of action
The nature of the antibacterial action of
О
В
furazolidone depends on the concentration of
the drug
О
Г
В
0608
А
О
Б
О
В
О
Г
В
0609
А
О
Б
О
В
Linezolid may cause hematologic
abnormalities (anemia, thrombocytopenia)
Correct statements regarding antimicrobial
agents are all except:
Nitroxoline may cause vision impairment
Fluoroquinolones interfere with DNA
replication and RNA formation
Nalidixic acid is used for urinary tract
infections
Furazolidone is used for intestinal infections
Correct statements regarding antimicrobial
agents are all except:
Nitroxoline is poorly absorbed from the
gastrointestinal tract
Linezolid has a bactericidal effect
Nitrofurans interfere with DNA replication and
RNA formation
Moxifloxacin is effective for infections caused
О
Г
by non-spore-forming (obligate) anaerobic
bacteria
В
0610
А
Correct statements regarding antimicrobial
agents are all except:
Furazolidone is poorly absorbed by their
gastrointestinal tract
Fluoroquinolones are effective for
О
Б
О
В
Dioxidine has a bactericidal effect
О
Г
Nalidixic acid disrupts RNA synthesis
В
0611
А
Pseudomonas aeruginosa infections
Correct statements regarding antimicrobial
agents are all except:
Nalidixic acid is effective for infections caused
by Pseudomonas aeruginosa
О
Б
Ciprofloxacin crosses the blood-brain barrier
О
В
Nitroxalin is active against some fungi
О
Г
В
0612
Moxifloxacin is more effective against grampositive bacteria than ciprofloxacin
Correct statements regarding antimicrobial
agents are all except:
А
Nitroxoline has a bactericidal effect
О
Б
Furazolidone is effective for trichomoniasis
О
В
О
Г
В
Linezolid disrupts protein synthesis on
ribosomes
Dioxidine is effective for Pseudomonas
aeruginosa infections
0613 The most effective anti-tuberculosis drug:
А
Isoniazid
О
Б
Streptomycin
О
В
Ethambutol
О
Г
В
0614
Sodium paraaminosalicylate (sodium
aminosalicylate)
Medium-effective anti-tuberculosis drugs are
all of the following except:
А
Rifampicin
О
Б
Ethambutol
О
В
Streptomycin
О
Г
Ethionamide
О
Д
Cycloserine
О
Е
Amikacin
В
0615
Antibiotics used as anti-tuberculosis drugs everything except:
А
Tetracycline
О
Б
Kanamycin
О
В
Amikacin
О
Г
Streptomycin
О
Д
Rifampicin
О
Е
Cycloserine
В
0616
RNA synthesis in mycobacterium tuberculosis
disrupts by:
А
Rifampicin
О
Б
Isoniazid
О
В
Cycloserine
О
Г
В
Sodium paraaminosalicylate (sodium
aminosalicylate)
0617 Sensitive to isoniazid:
А
Mycobacterium tuberculosis
О
Б
Gram-positive bacteria
О
В
Spirochetes
О
Г
Gram-negative bacteria
О
Д
Chlamydia
В
0618
The next infectious agents are sensitive to
pyrazinamide:
А
Mycobacterium tuberculosis
О
Б
Gram-negative bacteria
О
В
Gram-positive bacteria
О
Г
Chlamydia
В
0619
Isoniazid is characterized by everything
except:
А
Resilience develops slowly
О
Б
Affects mainly Mycobacterium tuberculosis
О
В
О
Г
О
Д
О
Е
В
Blocks the synthesis of mycolic acids in the
cell wall of mycobacteria
Resilience is evolving rapidly
Refers to the most effective anti-tuberculosis
drugs
Active against intracellular mycobacteria
0620 Everything is typical for rifampicin, except for:
А
Affects mainly Mycobacterium tuberculosis
О
Б
Has a broad spectrum of action
О
В
О
Г
Blocks DNA-dependent RNA polymerase
О
Д
Resilience is evolving rapidly
О
Е
Penetrates the blood-brain barrier
В
Refers to the most effective anti-tuberculosis
drugs
0621 Rifampicin can cause all side effects except:
А
Disorders of the central nervous system
О
Б
Allergic reactions
О
В
Dyspeptic disorders
О
Г
Liver damage
О
Д
Dysbacteriosis
В
0622
Streptomycin can cause all side effects
except:
А
Liver damage
О
Б
Hearing loss and vestibular disorders
О
В
Kidney damage
О
Г
Dysbacteriosis
О
Д
Allergic reactions
The effect of isoniazid on the central nervous
В
0623 system is manifested by all of the above,
except for:
А
Narcolepsy
О
Б
Insomnia
О
В
Psychomotor agitation
О
Г
Convulsions
В
0624 Vision impairment causes by:
А
Ethambutol
О
Б
Isoniazid
О
В
Streptomycin
О
Г
Rifampicin
В
0625
А
О
Б
О
В
О
Г
В
0626
А
О
Б
О
В
О
Г
В
0627
А
О
Б
Correct statements regarding anti-TB drugs
are everything except:
Sodium paraaminosalicylate (sodium
aminosalicylate) is administered intravenously
Streptomycin disrupts protein synthesis on
ribosomes
Isoniazid is one of the most effective antituberculosis drugs
Rifampicin blocks DNA-dependent RNA
polymerase
Correct statements regarding anti-TB drugs
are everything except:
Ethambutol can cause dysbiosis
Isoniazid disrupts the synthesis of mycolic
acids in the cell wall
Streptomycin may cause hearing loss and
vestibular disorders
Rifampicin is one of the most effective antituberculosis drugs
Correct statements regarding anti-TB drugs
are all except:
Ethambutol is one of the most effective antiTB drugs
Rifampicin is a broad-spectrum antibiotic
Sodium paraaminosalicylate (sodium
О
В
aminosalicylate) may cause dyspeptic
disorders
О
Г
В
0628
А
Isoniazid is a synthetic anti-tuberculosis drug.
Correct statements regarding anti-TB drugs
are all except:
Cycloserine is a synthetic anti-tuberculosis
drug
О
Б
Streptomycin is a broad-spectrum antibiotic
О
В
Isoniazid is neurotoxic
О
Г
В
0629
А
Ethambutol belongs to anti-tuberculosis drugs
with average effectiveness
Correct statements regarding antituberculosis drugs are all except:
Cycloserine disrupts the permeability of the
cytoplasmic membrane
О
Б
Strepomycin can cause dysbiosis
О
В
Ethambutol may cause visual impairment
О
Г
Rifampicin is hepatotoxic
В
0630
Correct statements regarding anti-TB drugs
are all except:
Sodium paraaminosalicylate (sodium
А
aminosalicylate) disrupts protein synthesis on
ribosomes
Resistance of mycobacteria to ethionamide
О
Б
О
В
Rifampicin May Cause Allergic Reactions
О
Г
Cycloserine disrupts cell wall synthesis
В
0631
А
О
Б
О
В
О
Г
В
0632
develops slowly
Correct statements regarding anti-TB drugs
are all except:
Streptomycin has a bacteriostatic effect
Sodium paraaminosalicylate (sodium
aminosalicylate) may cause allergic reactions
Isoniazid resistance of mycobacteria develops
rapidly
Cycloserine crosses the blood-brain barrier
Correct statements regarding anti-TB drugs
are all except:
А
Rifampicin is nephrotoxic
О
Б
Cycloserine may cause allergic reactions
О
В
Isoniazid is used for all forms of tuberculosis
О
Г
В
0633
А
О
Б
Mycobacterial resistance to ethambutol
develops slowly
Correct statements regarding anti-TB drugs
are all except:
Rifampicin resistance of mycobacteria
develops slowly
Isoniazid is acetylated in the body
Sodium paraaminosalicylate (sodium
О
В
aminosalicylate) is a para-aminobenzoic acid
antagonist
О
В
Г
Rifampicin is used for all forms of tuberculosis
0634 Antisyphilitic drugs are all except:
А
Aminoglycosides
О
Б
Benzylpenicillin preparations
О
В
Azithromycin
О
Г
Bismuth preparations
В
0635 The main antibiotics for syphilis are:
А
Benzylpenicillin preparations
О
Б
Ceftriaxone
О
В
Azithromycin
О
Г
Tetracyclines
О
Д
Erythromycin
В
0636
Reserve antibiotics for syphilis treatment are
all except:
А
Amikacin
О
Б
Ceftriaxone
О
В
Azithromycin
О
Г
Erythromycin
О
Д
Tetracyclines
В
0637 Benzylpenicillin drugs disrupts:
А
Treponema cell wall synthesis
О
Б
Protein synthesis on ribosomes
О
В
Permeability of the cytoplasmic membrane
О
Г
RNA synthesis
В
0638 Ceftriaxone disrupts:
А
Treponema cell wall synthesis
О
Б
Permeability of the cytoplasmic membrane
О
В
Protein synthesis on ribosomes
О
Г
RNA synthesis
В
0639
The side effects of bismuth preparations are
all except:
А
Hearing loss and vestibular disorders
О
Б
Diarrhea
О
В
О
Г
Liver damage
О
Д
Kidney damage
Lesions of the mucous membranes (gingivitis,
stomatitis)
Determine the drug: disrupts the synthesis of
the cell wall of treponema; has treponemicidal
action; is the main anti-syphilitic antibiotic;
В
0640 effective at all stages of syphilis; prescribed
parenterally 6-8 times a day; cause allergic
reactions, "exacerbation" reaction, has an
irritating effect:
А
Benzylpenicillin sodium salt (benzylpenicillin)
О
Б
Ceftriaxone
О
В
Erythromycin
О
Г
Biyoquinol
В
0641 Antiviral nucleoside analogs are all except:
А
Rimantadin
О
Б
Acyclovir
О
В
Zidovudine
О
Г
Ganciclovir
В
0642
For drugs that affect herpes viruses,
everything is true, except:
А
Effective mainly against influenza viruses
О
Б
Effective mainly against cytomegalovirus
О
В
Effective mainly against Herpes zoster
О
Г
В
0643
Effective mainly against the Herpes simplex
virus
Drugs effective for diseases caused by the
Herpes simplex virus are all listed, except:
А
Ganciclovir
О
Б
Acyclovir
О
В
Valacyclovir
О
Г
Penciclovir
В
0644
A drug that has a predominant effect on
cytomegalovirus:
А
Ganciclovir
О
Б
Zidovudine
О
В
Acyclovir
О
Г
Amiksin
В
0645
Drugs effective against influenza type A virus
are all except:
А
Valacklovir
О
Б
Rimantadin
О
В
Umifenovir
О
Г
Oseltamivir
В
0646
The release of virions from the cell is inhibited
by:
А
Oseltamivir
О
Б
Acyclovir
О
В
Abacavir
О
Г
Rimantadin
В
0647
А
All of the following are characteristics of
Acyclovir, except for:
Does not penetrate the blood-brain barrier
when used systemically
The drug's metabolite, acyclovir triphosphate,
О
Б
inhibits the DNA polymerase of the virus,
which leads to inhibition of viral DNA
replication.
О
В
О
Г
О
Д
О
Е
В
0648
Penetrates through the hematoencephalic
bao'er with systemic use.
Purine nucleoside analog
Effective mainly for infections caused by
Herpes simplex and Herpes zoster
Administered orally, intravenously, topically
All of the following are characteristics of
Ganciclovir, except for:
А
Ineffective against cytomegalovirus
О
Б
Inhibits viral DNA polymerase
О
В
Nucleoside structure
О
Г
Ineffective against herpes simplex virus
О
Д
Intravenous
О
Е
В
0649
А
Causes anxiety, abdominal pain, neutropenia,
anemia
All of the following are characteristics of
rimantadine, except:
Inhibits viral RNA synthesis
Inhibits membrane protein M2 of influenza
О
Б
О
В
Disrupts the release of the viral genome
О
Г
Adamantane derivative
О
Д
Effective against influenza type A virus
О
Е
Assign inside
В
0650
А
type A virus
For ribavirin, all of the following are
characteristics, except:
Ribavirin triphosphate disrupts the process of
"assembly" of virions
Monophosphate metabolite of the drug
О
Б
disrupts the synthesis of guanosine
nucleotides
О
В
О
Г
О
Д
О
Е
В
0651
О
Ribavirin triphosphate inhibits viral RNA
polymerase and disrupts mRNA production
Guanosine analog
Effective against influenza A and B viruses,
respiratory syncytial virus
Assign inside, inhalation, intravenous
All of the following are true for saquinavir,
except for:
А
Interferes with the formation of DNA and RNA
Б
HIV protease inhibitor
Interferes with the reproduction of HIV by
О
В
inhibiting the formation of structural proteins
and enzymes
О
Г
Derivative of peptides
О
Д
Assign inside
В
0652
А
О
Б
О
В
All statements regarding antiviral agents are
correct except:
Ribavirin disrupts the process of "assembly" of
virions
Saquinavir - HIV protease inhibitor
Acyclovir is effective for diseases caused by
the Herpes simplex virus
О
Г
В
0653
Rimantadine blocks influenza A virus M2
protein
All statements regarding antiviral agents are
correct except:
А
Zanamivir inhibits viral genome release
О
Б
Zidovudine is used for HIV infection
О
В
О
Г
В
0654
Saquinavir inhibits the synthesis of "late" viral
proteins
Amiksin has immunostimulating properties
Drugs used for the prevention and treatment
of malaria are all of the following except:
А
Furazolidone
О
Б
Mefloquine
О
В
Chloroquine
О
Г
Hydroxychloroquine
В
0655
Anti-amebic drugs are all of the following
except:
А
Levamisole
О
Б
Tetracyclines
О
В
Metronidazole
О
Г
Chloroquine
В
0656
The drugs used for balantidiasis are all listed,
except:
А
Furazolidone
О
Б
Metronidazole
О
В
Tetracyclines
О
Г
Ornidazole
В
0657
Antimalarial drugs with hematoschizotropic
activity are all of the following, except:
А
Metronidazole
О
Б
Chloroquine
О
В
Quinine
О
Г
Hydroxychloroquine
В
0658 The mechanism of action of chloroquine is:
А
Inhibition of the enzyme that utilizes
erythrocyte heme
О
Б
Inhibition of Plasmodium Protein Synthesis
О
В
Direct toxic effect on Plasmodium
О
Г
В
0659
Destruction of the cytoplasmic membrane of
the plasmodium
Direct-acting anti-amebic drugs, are all of the
following except:
А
Tetracyclines
О
Б
Chloroquine
О
В
Tinidazole
О
Г
Metronidazole
В
0660
An anti-amebic drug effective for any
localization of amoebas:
А
Metronidazole
О
Б
Chloroquine
О
В
Mebendazole
О
Г
Tetracycline
В
0661
Metronidazole is used for all indications,
except for:
А
Malaria
О
Б
Trichomoniasis
О
В
Giardiasis
О
Г
Amoebiasis
О
Д
В
Infections caused by non-spore-forming
(obligate) anaerobic bacteria
0662 Chloroquine can cause all side effects except:
А
Kidney damage
О
Б
Liver damage
О
В
Visual impairment
О
Г
Dermatitis
О
Д
О
Е
В
0663
Decreased resistance to bacterial and viral
infections
Hematological disorders (agranulocytosis,
anemia)
Metronidazole can cause all side effects
except:
А
Visual impairment
О
Б
Dyspeptic disorders
О
В
Impaired coordination of movements, tremor
О
Г
В
Teturam-like effect when combined with ethyl
alcohol
0664 Furazolidone can cause all side effects except:
А
Dysbacteriosis
О
Б
Dyspeptic disorders
О
В
О
Г
Hematological disorders (leukopenia, anemia)
О
Д
Anorexia
Teturam-like effect when combined with ethyl
alcohol
Determine the antiprotozoal drug: used to
eliminate clinical manifestations and individual
В
0665
chemoprophylaxis of malaria; the resistance of
malarial plamodia develops slowly; effective
for extraintestinal amebiasis; appoint orally
and parenterally:
А
Chloroquine
О
Б
Metronidazole
О
В
Tetracycline
Determine the antiprotozoal drug: used to
В
0666
eliminate clinical manifestations and individual
chemoprophylaxis of malaria; the duration of
action is superior to quinine; appoint inside:
А
Mefloquine
О
Б
Nimorazole
О
В
Nifuratel
В
0667
А
О
Б
All statements regarding antiprotozoal drugs
are correct, except:
Metronidazole inhibits hematopoiesis
Chloroquine acts on erythrocyte forms of
plasmodia
The effectiveness of tetracycline in amebiasis
О
В
is associated with the ability to suppress the
bacterial flora of the intestine
О
Г
В
0668
Furazolidone is effective for giardiasis
The drugs used for the treatment of
candidiasis are all of the following, except for:
А
Terbinafine
О
Б
Nystatin
О
В
Clotrimazole
О
Г
Natamycin
В
0669
Polyene antifungal antibiotics are all of the
following except:
А
Griseofulvin
О
Б
Nystatin
О
В
Amphotericin B
О
Г
Natamycin
В
0670
А
All of the following is characteristic of nystatin,
except:
Well absorbed from the gastrointestinal tract
Violates the permeability of the cell membrane
О
Б
О
В
Polyene antibiotic
О
Г
Poorly absorbed from the gastrointestinal tract
О
Д
Used for candidiasis
О
Е
О
Ж
В
0671
А
of fungi
Mushroom resistance practically does not
occur
Assign inside, topically
For fluconazole, all of the following is
characteristic, except:
Poorly absorbed from the gastrointestinal tract
Violates the synthesis of ergosterol of the cell
О
Б
О
В
Triazole derivative
О
Г
Penetrates the blood-brain barrier
О
Д
Used for systemic mycoses
О
Е
Effective for nystatin-resistant candidiasis
О
Ж
Assign inside, intravenously
В
0672
А
membrane of fungi
All of the following is characteristic of
terbinafine, except:
Violates the permeability of the cell membrane
of fungi
О
Б
О
В
О
Г
О
Д
Assign inside
О
Е
Prescribed locally
В
Synthetic antifungal agent
Violates the synthesis of ergosterol of the cell
membrane of fungi
Accumulates in the skin, subcutaneous fatty
tissue, nail plates
0673 Nystatin can cause:
А
Dyspeptic disorders
О
Б
Liver damage
О
В
Kidney damage
О
Г
Dysbacteriosis
В
0674
А
With regard to antifungal agents, everything
listed is true, except:
Nystatin is neurotoxic
Ketoconazole disrupts the synthesis of
О
Б
О
В
Amphotericin B is used for systemic mycoses
О
Г
Terbinafine is effective for dermatomycosis
В
0675
А
О
Б
О
В
О
Г
В
0676
А
О
Б
О
В
О
Г
В
0677
ergosterol in cell membranes
With regard to antifungal agents, everything
listed is true, except:
Caspofungin is administered orally
Terbinafine disrupts the synthesis of
ergosterol in cell membranes
Griseofulvin is used for dermatomycosis
Nystatin disrupts the permeability of cell
membranes
With regard to antifungal agents, everything
listed is true, except:
Griseofulvin is effective for systemic mycoses
Amphotericin A accumulates with repeated
administration
Amorolfine comes in the form of nail polish
Nystatin is poorly absorbed from the
gastrointestinal tract.
For intestinal cestodosis, the next drug is
used:
А
Praziquantel
О
Б
Mebendazole
О
В
Levamisole
О
Г
Piperazine
О
Д
Albendazole
В
0678
With intestinal trematodosis (metagonimosis)
the next drug is used:
А
Praziquantel
О
Б
Levamisole
О
В
Pirantel
О
Г
Mebendazole
В
0679
With extraintestinal trematodes, the next drug
is used:
А
Praziquantel
О
Б
Levamisole
О
В
Pirantel
О
Г
Mebendazole
В
0680
А
О
Б
О
В
О
Г
О
Д
О
Е
В
All of the following is typical for Praziquantel,
except:
Causes paralysis in helminths by enhancing
the effect of GABA
Disrupts calcium metabolism in helminths
It is used in the treatment of intestinal
strongyloidosis
It is used in the treatment of intestinal
cestodoses and trematoses
It is used for the treatment of extraintestinal
trematodes
It is used to treat extraintestinal cysticercosis
0690 The next drug is used in trichinosis:
А
Mebendazole
О
Б
Praziquantel
О
В
Levamisole
О
Г
Pirantel
Determine the drug: disrupts the synthesis of
В
0691 cellular β-tubulin and the synthesis of ATP,
causing paralysis of the helminth's body:
А
Mebendazole
О
Б
Praziquantel
О
В
Pirantel
О
Г
Piperazine adipate
В
0692
А
All statements regarding antihelmintics are
correct, except:
Albendazole is effective for intestinal
cestodosis
Piperazine paralyzes nematodes, which
О
Б
promotes their excretion from the intestine in a
living state
О
В
Praziquantel is used for trematodes
Mebendazole is used both for the treatment of
О
Г
intestinal nematodes, and for extraintestinal
trichinosis and echinococcosis
В
0693 Alkylating agents are all listed, except:
А
Dactinomycin
О
Б
Sarcolysin
О
В
Cyclophosphamide
О
Г
Mielosan
В
0694
Cyclophosphamide is an antineoplastic drug
from the group:
А
Alkylating agent
О
Б
Antimetabolite
О
В
Antibiotic
О
Г
Enzyme preparation
О
Д
Hormonal agent
О
Е
Herbal antineoplastic agent
О
Ж
Cytokine
В
0695
Sarcolysin is an antineoplastic drug from the
group:
А
Alkylating agent
О
Б
Antibiotic
О
В
Hormonal drug
О
Г
Radioactive isotope
О
Д
Enzyme preparation
В
0696 Fluorouracil:
А
Antimetabolite
О
Б
Antibiotic
О
В
Enzyme preparation
О
Г
Platinum drug
В
0697 Mercaptopurine:
А
Antimetabolite
О
Б
Platinum drug
О
В
Cytokine
О
Г
Vegetable matter
В
0698 Methotrexate:
А
Antimetabolite
О
Б
Vegetable matter
О
В
Alkylating agent
О
Г
Platinum preparation
В
0699 Tamoxifen:
А
Androgen antagonist
О
Б
Cytokine
О
В
Monoclonal antibody preparation
О
Г
Estrogen antagonist
В
0700 Vincristine:
А
Herbal preparation
О
Б
Alkylating compound
О
В
Antimetabolite
О
Г
Cytokine
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