Level 1 (Primary) Blair Upper Cervical Specific Presented by Dr Jeffrey Hannah Advanced Blair Certified Instructor The Rationale of Blair Upper Cervical Specific Neuroanatomy Review Dr Jeffrey Hannah Advanced Blair Certified Instructor Atlas Health Australia, Pty Ltd North Lakes, QLD The Upper Cervical Rationale “Separate & Distinct Profession” CHIROPRACTIC Medicine • Philosophy • Outside-In INSIDE-OUT • Science •S Germs, UBLUXATION Genes • Art • Drugs, ADJUSTMENT Surgery, Therapy RESTORE (treat /CORRECT effects)CAUSE • Subluxation M isalignment O cclusion P ressure on Nerve Dr BJ Palmer, DC PhC I nterference of Mental Impulse 1882-1961 3D Inability to Self-Correct The Upper Cervical Rationale Researching the Known Man MO3 • Spinograph (X-Ray, 1910) PI • Neurocalometer (24 Aug 1924) + ‘Tempometer & ’Calograph PI • Electroencephaloneuro mentimpograph (1934) MO3 • “Wet Specimen” (1938) C1-C3 Architecture Three-Dimensional Motion • FLEXIBILITY VS STABILITY • NO INTERVERTEBRAL DISC C1-C3 Neurocanal Stability • DENTATE LIGAMENT STRUCTURE • MYODURAL BRIDGES Lack of Corrective Control • NO ACCESSORY INNERVATION • NO COLLATERAL MUSCLES Mechanical Cord Sensitivity Local Effects • Medullary Nuclei • NUCLEUS TRACTUS SOLITARIUS • RVM & RVL NUCLEI • DORSAL MOTOR NUCLEI • Craniocervical Nuclei • V, VIII, IX-X, XI, XII • C1-C4 • Sensory • Motor Mechanical Tract Sensitivity Distant Effects • Tracts • Descending • Ascending • Bidirectional • SUPERIOR CERVICAL SYMPATHETIC GANGLION • VASCULAR BRANCHES • LYMPHATIC BRANCHES • Vagus Nerve (X) • Visceral Plexuses Dystrophy Local Effects (Upper Cervical) • Neurocanal • CEREBROSPINAL FLUID • VERTEBROBASILAR ARTERIES • CEREBROSPINAL VEINS • Trophic Supplies • Direct • Brainstem • Cerebellum • Indirect • Hypothalamus • Cortex • Spinal Cord Dysafferentation Subluxation (MOPI3) → • Malposition & Dyskinesia • Aberrant Gen Somatic Afferent (GSA) • “Congestion” (Gate Theory) • “Re-routing” (Plasticity) • “Spillover” (Interference) Craniocervical Syndrome Grostic JD. Dentate ligament-cord distortion hypothesis. Chirp Res J. 1988;1:1. [Kessinger R. The Medullary Lock.] Sharpless SK. Susceptibility of spinal roots to compression block. The Research Status of Spinal Manipulative Therapy. NINCDS monograph 15, DHEW publication (NIH) 76-998:155, 1975. “A pressure of only 10 mm Hg produced a significant conduction block, the potential falling to 60% of its initial value in 15 minutes, and to half of its initial value in 30 minutes.” Upper Cross Syndrome Cailliet R. Neck and Arm Pain (2nd Ed). FA Davis. 1981. [The effective weight of the head, 3-5Kg, on the lower cervical joints doubles per 2.5 cm of anterior head carriage.] Schleip R. Fascial plasticity - a new neurobiological explanation: part 2. J Bodywork Movement Therap, 2003;7(2): 104-116. “Fascia is densely innervated by mechanoreceptors which are responsive to myofascial manipulation. They are intimately connected with the central nervous system and specially with the autonomic nervous system.” Central Processing Errors Haavik-Taylor H, Holt K, and Murphy B. Exploring the neuromodulatory effects of the vertebral subluxation and chiropractic care. Chiropr J Aust, 40;2010:37-44. Haavik-Taylor H and Murphy B. The effects of spinal manipulation on central integration of dual somatosensory input observed after motor training: a crossover study. J Manipulative Physiol Therap. 33(4); 2010:261-272. “This study suggests that cervical spine manipulation not only alters cortical integration of dual somatosensory input but also alters the way the central nervous system responds to subsequent motor training tasks. HPA & HPT Axis Dysfunction Zoccal DB, Furuya WI, Bassi M, Colombari DSA, Colombari E. The nucleus of the solitary tract and the coordination of respiratory and sympathetic activities. Frontiers in Physiology. 2014;5:238. Bakris G, Dickholtz M Sr, Meyer PM, et al. Atlas vertebra realignment and achievement of arterial pressure goal in hypertensive patients: a pilot study. J Hum Hypertens. 2007 May;21(5):347-52. “No adverse effects were recorded. We conclude that restoration of Atlas alignment is associated with marked and sustained reductions in BP similar to the use of two-drug combination therapy.” HPA & HPT Axis Dysfunction Marty V, El Hachmane M, Amédée T. Dual modulation of synaptic transmission in the nucleus tractus solitarius by prostaglandin E2 synthesized downstream of IL-1β. European Journal of Neuroscience. June 2008;27(12):3132–3150. Selano JL, Hightower BC, Pfleger B, et al: “The effects of specific upper cervical adjustments on the CD4 counts of HIV positive patients.” Chiropractic Research Journal 1994;3(1):32. “The effect of specific upper cervical adjustments on the immune system CD4 cell counts of [10] HIV positive individuals was measured by CD4/mm3 in the blood. … A 48% increase in CD4 cells was demonstrated over the six month duration of the study for the adjusted group.” Neurodegenerative Conditions Elster EL. Eighty-one patients with multiple sclerosis and Parkinson's disease undergoing upper cervical chiropractic care to correct vertebral subluxation: a retrospective analysis. J Vertebr Sublux Res. 2004;2:1-9. Sandro Mandolesi S, Marceca G, Moser J, et al. Preliminary results after upper cervical chiropractic care in patients with chronic cerebro-spinal venous insufficiency and multiple sclerosis. Ann. Ital. Chir., 2015 86: 192-200. ”We believe that the Upper Cervical correction on C1-C2 could be the main non-invasive treatment of the CCSVI mechanical type in patients with MS.” Neurodegenerative Conditions Flanagan MF. The Downside of Upright Posture. Two Harbors Press, 2010. Flanagan MF. The role of the craniocervical junction in craniospinal hydrodynamics and neurodegenerative conditions. Neurology Research International, 2015. “The craniocervical junction (CCJ) is a potential choke point for craniospinal hydrodynamics and may play a causative or contributory role in the pathogenesis and progression of neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, MS, and ALS, as well as many other neurological conditions including hydrocephalus, idiopathic intracranial hypertension, migraines, seizures, silent-strokes, affective disorders, schizophrenia, and psychosis.” Myalgic Encephalopathy Rosa S, Baird JW. The craniocervical junction: observations regarding the relationship between misalignment, obstruction of cerebrospinal fluid flow, cerebellar tonsillar ectopia, and image-guided correction. Smith FW, Dworkin JS (eds): The Craniocervical Syndrome and MRI. Basel, Karger, 2015, pp 48-66. Vestibular Syndromes Kulkarni V, Chandy MJ, Babu KS. Quantitative study of muscle spindles in suboccipital muscles of human foetuses. Neurol Indfa, 2001;49(4):355-9. “The proprioceptive inputs from the cervical musculature play an important role in head-eye coordination and postural processes. The spindle density of superior oblique muscle was found to be 190, that of inferior oblique was 242 and the rectus capitis posterior contained 98 spindles per gram of muscle. No tendon organs were seen.” danmurphydc.com Vestibular Syndromes Heikkilä HV, Wenngren BI. Cervicocephalic kinesthetic sensibility, active range of cervical motion, and oculomotor function in patients with whiplash injury. Arch Phys Med Rehabil. 1998 Sep;79(9):1089-94. Burcon MT. Health Outcomes Following Cervical Specific Protocol in 300 Patients with Meniere’s Followed Over Six Years. Journal of Upper Cervical Chiropractic Research ~ June 2, 2016 ~ Pages 13-23. “Vertigo intensity rated by 300 patients on a scale of 0 to 10, with 10 being the worst imaginable. Prior to treatment mean score was 8.5, six weeks post treatment average was down to 3.0 … Ninety seven percent claimed a dramatic improvement in vertigo.” Craniofacial Syndromes Losert-Bruggner B, Hülse M, Hülse R. Fibromyalgia in patients with chronic CCD and CMD - a retrospective study of 555 patients. Cranio. 2017 Jun 5:1-9. Westersund CD, Scholten J, Turner RJ. Relationship between craniocervical orientation and center of force of occlusion in adults. Cranio. 2016 Oct 20:1-7. “These findings may suggest interconnectivity between the CCJ and an individual's occlusal contacts and support the need for further integration between chiropractors and dentists seeking to comanage temporomandibular joint disorders.” Neuromuscular Conditions Robinson SS, Collins KF, Grostic JD. A retrospective study; patients with chronic low back pain managed with specific upper cervical adjustments. Chiropr Res J. 1993;2(4): 10-6. Eriksen. Upper Cervical Subluxation Complex. 2004:247. Neuromuscular Conditions Schwatzbauer J, Koller J, Schwarzbauer M et al. Athletic performance and physiological measures in baseball players following upper cervical chiropractic care: a pilot study. J Vertebral Subluxation Res, 1997;1(4):33-9. “The results showed significant improvement in fourteen weeks in muscle strength and long jump distance in the group receiving adjustments. … Evaluations of these trends in the group receiving chiropractic care revealed decreases in resting blood pressure and pulse rate as well as pulse rate following tread mill activity.” Additional Resources - Texts Upper Cervical Subluxation Complex: A Review of the Medical & Chiropractic Literature. Eriksen. 2004. The Craniocervical Syndrome & MRI. Smith & Dworkin. 2015. The Downside of Upright Posture. Flanagan. 2010 The Craniocervical Syndrome. Vernon. 2001. Additional Resources - Citations Journal Upper Cervical Chiropractic Research (JUCCR). McCoy Press. uppercervicalsubluxation.com Dr Kirk Eriksen drkirkeriksen.com/research.html UPC Spine (Greg Buchanan) upcspine.com Upper Cervical Advocates (J & R Tomasi) uppercervicaladvocates.com Additional Resources - Education The Doctors Who Give No Medicine. Hannah. 2012. The Best Kept Secret in Healthcare. Drury. 2013. The Power of Upper Cervical DVD + Upper Cervical Care: 17 Questions DVD + Other Resources healthychiropractice.com/store/c1/ Featured_Products.html Rationale & Research Craniocervical Syndrome Grostic JD. Dentate ligament-cord distortion hypothesis. Chirp Res J. 1988;1:1. [Kessinger R. The Medullary Lock.] Sharpless SK. Susceptibility of spinal roots to compression block. The Research Status of Spinal Manipulative Therapy. NINCDS monograph 15, DHEW publication (NIH) 76-998:155, 1975. “A pressure of only 10 mm Hg produced a significant conduction block, the potential falling to 60% of its initial value in 15 minutes, and to half of its initial value in 30 minutes.” Upper Cross Syndrome Cailliet R. Neck and Arm Pain (2nd Ed). FA Davis. 1981. [The effective weight of the head, 3-5Kg, on the lower cervical joints doubles per 2.5 cm of anterior head carriage.] Schleip R. Fascial plasticity - a new neurobiological explanation: part 2. J Bodywork Movement Therap, 2003;7(2): 104-116. “Fascia is densely innervated by mechanoreceptors which are responsive to myofascial manipulation. They are intimately connected with the central nervous system and specially with the autonomic nervous system.” Neuromuscular Conditions Robinson SS, Collins KF, Grostic JD. A retrospective study; patients with chronic low back pain managed with specific upper cervical adjustments. Chiropr Res J. 1993;2(4):10-6. Schwarzbauer J, Koller J, Schwarzbauer M et al. Athletic performance and physiological measures in baseball players following upper cervical chiropractic care: a pilot study. J Vertebral Subluxation Res, 1997;1(4):33-9. Eriksen. Upper Cervical Subluxation Complex. 2004:247. Central Processing Errors Haavik-Taylor H, Holt K, and Murphy B. Exploring the neuromodulatory effects of the vertebral subluxation and chiropractic care. Chiropr J Aust, 40;2010:37-44. Haavik-Taylor H and Murphy B. The effects of spinal manipulation on central integration of dual somatosensory input observed after motor training: a crossover study. J Manipulative Physiol Therap. 33(4); 2010:261-272. “This study suggests that cervical spine manipulation not only alters cortical integration of dual somatosensory input but also alters the way the central nervous system responds to subsequent motor training tasks. Medullary Dysfunction Zoccal DB, Furuya WI, Bassi M, Colombari DSA, Colombari E. The nucleus of the solitary tract and the coordination of respiratory and sympathetic activities. Frontiers in Physiology. 2014;5:238. Bakris G, Dickholtz M Sr, Meyer PM, et al. Atlas vertebra realignment and achievement of arterial pressure goal in hypertensive patients: a pilot study. J Hum Hypertens. 2007 May;21(5):347-52. “No adverse effects were recorded. We conclude that restoration of Atlas alignment is associated with marked and sustained reductions in BP similar to the use of two-drug combination therapy.” HPA & HPT Axis Dysfunction Marty V, El Hachmane M, Amédée T. Dual modulation of synaptic transmission in the nucleus tractus solitarius by prostaglandin E2 synthesized downstream of IL-1β. European Journal of Neuroscience. June 2008;27(12):3132–3150. Selano JL, Hightower BC, Pfleger B, et al: “The effects of specific upper cervical adjustments on the CD4 counts of HIV positive patients.” Chiropractic Research Journal 1994;3(1):32. “The effect of specific upper cervical adjustments on the immune system CD4 cell counts of [10] HIV positive individuals was measured by CD4/mm3 in the blood. … A 48% increase in CD4 cells was demonstrated over the six month duration of the study for the adjusted group.” Neurodegenerative Conditions Elster EL. Eighty-one patients with multiple sclerosis and Parkinson's disease undergoing upper cervical chiropractic care to correct vertebral subluxation: a retrospective analysis. J Vertebr Sublux Res. 2004;2:1-9. Sandro Mandolesi S, Marceca G, Moser J, et al. Preliminary results after upper cervical chiropractic care in patients with chronic cerebro-spinal venous insufficiency and multiple sclerosis. Ann. Ital. Chir., 2015 86: 192-200. ”We believe that the Upper Cervical correction on C1-C2 could be the main non-invasive treatment of the CCSVI mechanical type in patients with MS.” Myalgic Encephalopathy Rosa S, Baird JW. The craniocervical junction: observations regarding the relationship between misalignment, obstruction of cerebrospinal fluid flow, cerebellar tonsillar ectopia, and image-guided correction. Smith FW, Dworkin JS (eds): The Craniocervical Syndrome and MRI. Basel, Karger, 2015, pp 48-66. Vestibular Syndromes Heikkilä HV, Wenngren BI. Cervicocephalic kinesthetic sensibility, active range of cervical motion, and oculomotor function in patients with whiplash injury. Arch Phys Med Rehabil. 1998 Sep;79(9):1089-94. Burcon MT. Health Outcomes Following Cervical Specific Protocol in 300 Patients with Meniere’s Followed Over Six Years. Journal of Upper Cervical Chiropractic Research ~ June 2, 2016 ~ Pages 13-23. “Vertigo intensity rated by 300 patients on a scale of 0 to 10, with 10 being the worst imaginable. Prior to treatment mean score was 8.5, six weeks post treatment average was down to 3.0 … Ninety seven percent claimed a dramatic improvement in vertigo.” Craniofacial Syndromes Losert-Bruggner B, Hülse M, Hülse R. Fibromyalgia in patients with chronic CCD and CMD - a retrospective study of 555 patients. Cranio. 2017 Jun 5:1-9. Westersund CD, Scholten J, Turner RJ. Relationship between craniocervical orientation and center of force of occlusion in adults. Cranio. 2016 Oct 20:1-7. “These findings may suggest interconnectivity between the CCJ and an individual's occlusal contacts and support the need for further integration between chiropractors and dentists seeking to comanage temporomandibular joint disorders.” Is Subluxation Real? Blair WG. Primary and adaptative malformations and Procedures for solving malformation problems. Research Thesis. Palmer College of Chiropractic. May 1968. “In non-fractured, non-dislocated misalignment of the Occipito-Atlanto segments at the Occipito-Atlanto articulation, one Atlanto lateral mass travels longitudinally, either anteriorly or posteriorly, (whichever the case might be) along the longitudinal articular axis of its corresponding occipital condyle while the partner lateral mass travels either transversely or obliquely across the longitudinal articular axis of its corresponding occipital condyle and in a plane parallel to the longitudinal axis of the articulation which presents true longitudinal misalignment.” Original Resources GREEN BOOKS • The Subluxation Specific, The Adjustment Specific ✭ (18) • Researching the Known Man (19) • Precise, Posture-Constant Comparative Spinographs ✭ (20) • Modern X-Ray Prac & Chiropr Spinography (21) - Remier • Clinical Controlled Chiropr Research ✭ (25) • Answers (28) Contemporary Resources - Texts Upper Cervical Subluxation Complex: A Review of the Medical & Chiropractic Literature. Eriksen. 2004. The Craniocervical Syndrome & MRI. Smith & Dworkin. 2015. The Downside of Upright Posture. Flanagan. 2010 The Craniocervical Syndrome. Vernon. 2001. Contemporary Resources - Citations Journal Upper Cervical Chiropractic Research (JUCCR). McCoy Press. uppercervicalsubluxation.com Dr Kirk Eriksen drkirkeriksen.com/research.html UPC Spine (Greg Buchanan) upcspine.com Upper Cervical Advocates (J & R Tomasi) uppercervicaladvocates.com Contemporary Resources - Education The Doctors Who Give No Medicine. Hannah. 2012. The Best Kept Secret in Healthcare. Drury. 2013. The Power of Upper Cervical. Storyville Studios. 2007. II. Blair & Supporting Research 1. Original Blair Research a. Blair WG. Research; for evaluation; for progress. Intl Rev Chiropr 1968;22(8): 8-11. b. Blair WG. Research: for evaluation; for progress. Intl Rev Chiropr 1968;22(9): 10-14. c. Blair WG. Research: for evaluation; for progress. Intl Rev Chiropr 1968;22(12):14-16. d. Blair WG. Blair Upper Cervical Spinographic Research Primary and Adaptive malformations, Procedures for Solving Malformation Problems: Blair Principle of Occipito-Atlanto Misalignment. Ph.C. Thesis, Palmer College of Chiropractic, 1968. 2. Asymmetry a. Gottlieb MS. Absence of symmetry in superior articular facets on the first cervical vertebra in humans: implications for diagnosis and treatment. J Manip Physiol Ther. 1994 Jun;17(5):314-20. b. Febbo TA, Morrison R, Valente R. Asymmetry of the occipital condyles: a computer-assisted analysis. J Manipulative Physiol Ther. 1992 Nov-Dec; 15(9):565-9. c. Naderia S, Kormanb E, Cıtak G, et al. Morphometric analysis of human occipital condyle. Clinical Neurology and Neurosurgery 107 (2005) 191–199 3. Articular Margins a. Briggs L, Hart J, Navis M, Clayton S, Boone R. Surface area congruence of atlas superior articulating facets and occipital condyles. Journal of Chiropractic Medicine. 2008;7(1):9-16. doi:10.1016/j.jcme.2007.08.007. “All 3 methods revealed that the articular surfaces of the atlas and corresponding or contralateral condyle for specimens used in this study were not an exact match.” b. Addington EA, Hubbard TA. Surface area congruence of atlas superior articulating facets and occipital condyles. Journal of Chiropractic Medicine. 2009;8(2):92-93. doi:10.1016/j.jcm.2008.12.004. “Blair does state broadly that “the articulations of the body perfectly match at the articular surfaces”; but he subsequently restricts his consideration to the “comparison of articular surfaces at their margins,” advancing no specific hypothesis as to surface areas. Finding that the medial margins of the AO articulations are “seldom well-defined” and “do not offer us articular surface comparison,” he developed the Blair Oblique Protractoviews specifically to image the most anterolateral or “distal condyle lateral mass margins” parallel to the longitudinal axis of each articulation. Viewing even these distal margins at too posterior or too anterior a point can be misleading as to articular alignment.” 4. X-ray Reliability & Analysis a. Hubbard TA, Vowles BM, Forest T. Inter- and intraexaminer reliability of the Blair protractoview method: examination of a chiropractic radiographic technique. Journal of Chiropractic Medicine. 2010;9(2):60-68. doi:10.1016/ j.jcm.2010.02.004. b. Hubbard TA, Pickar JG, Lawrence DJ. Radiographic analysis of the anterior to posterior open mouth (APOM) cervical spine view: frequency of atlas transverse process overlap of the inferior tip of the mastoid process. J Manipulative Physiol Ther. 2012 Jul;35(6):477-85. doi: 10.1016/j.jmpt. 2012.07.007. c. Eriksen K, The Sigler and Howe Study? Vector; 1999;2(4). d. Harrison DE, Harrison DD, Troyanovich SJ. Reliability of spinal displacement analysis of plain X-rays: a review of commonly accepted facts and fallacies with implications for chiropractic education and technique.J Manipulative Physiol Ther. 1998 May;21(4):252-66. e. Owens EF. Line drawing analyses of static cervical X ray used in chiropractic. J Manipulative Physiol Ther. 1992 Sep;15(7):442-9. “Reliability studies exist showing that inter- and intraexaminer reliability are sufficient to measure lateral and rotational displacements of C1 to within +/- 1 degree. It is not known how much of the changes that are seen in pre/postradiograph sets are due to positioning changes of the patient between radiographic procedure, and how much are due to actual changes of skeletal relationships brought about by adjustment.” f. Harrison DE, Harrison DD, Colloca CJ, et al. Repeatability over time of posture, radiograph positioning, and radiograph line drawing: an analysis of six control groups. J Manipulative Physiol Ther. 2003 Feb;26(2):87-98. “In 48 out of 50 measurements, the differences between initial and follow-up radiographs are less than 1.5 degrees and 2 mm. These measurements indicate that posture is repeatable, radiographic positioning is repeatable, and radiographic line drawing analysis for spinal displacement is highly reliable. The scientific literature on these topics also indicates the repeatability of posture, radiographic positioning, and radiographic line drawing. “… These results contradict common claims made by several researchers and clinicians in the indexed literature. Chiropractic radiologic education and publications should reflect the recent literature, provide more support for posture analysis, radiographic positioning, radiographic line drawing analyses, and applications of posture and radiographic procedures for measuring spinal displacement on plain radiographs.” g. Owens EF, Henderson CN, Gudavalli MR, Pickar JG. Head repositioning errors in normal student volunteers: a possible tool to assess the neck's neuromuscular system. Chiropr Osteopat. 2006 Mar 6;14:5. “During the neck extension test, actively contracting the posterior neck muscles evoked an undershoot of the target position by 2.1 degrees (p <0.001). No differences in repositioning were found during the lateral flexion test.” h. Hallgren RC, Andary MT. Undershooting of a neutral reference position by asymptomatic subjects after cervical motion in the sagittal plane. J Manipulative Physiol Ther. 2008 Sep;31(7):547-52. doi: 10.1016/j.jmpt. 2008.08.011. i. Eriksen K. Comparison between upper cervical x-ray listings and technique analyses utilizing a computerized database. Chiropr Res J. 1996;3(2):13-24. j. Grostic JD, DeBoer KF. Roentgenographic measurement of atlas laterality and rotation: a retrospective pre- and post-manipulation study. J Manip Physiol Ther. 1982;5(2):63-71. k. Eriksen K. Owens EF. Upper cervical post x-ray reduction and its relationship to symptomatic improvement and spinal stability. Chiropr Res J. 1997;4(1): 10-7. “The patients in this doctor’s practice had better outcome on the average, based on the improvement of clinical signs and the rediuced need to follow-up adjustment, when the occipito-atlanto-axial subluxation complex was reduced by at lease 50% after the first adjustment.” 5. Leg Length Analysis a. Cooperstein R, Morschhauser E, Lisi AJ. Cross-Sectional Validity Study of Compressive Leg Checking in Measuring Artificially Created Leg Length Inequality. Journal of Chiropractic Medicine. 2004;3(3):91-95. doi:10.1016/ S0899-3467(07)60092-5. “Instrumented, compressive leg checking seems highly accurate, detecting artificial changes in leg length of 2–3 mm, and thus possesses concurrent validity assessed against artificial LLI. Pre- and post leg check differences should exceed about 4–6 mm to be highly confident a real change has occurred.” b. Knutson GA. Anatomic and functional leg-length inequality: A review and recommendation for clinical decision-making. Part I, anatomic leg-length inequality: prevalence, magnitude, effects and clinical significance. Chiropractic & Osteopathy 2005, 13:11 doi:10.1186/1746-1340-13-11. c. Knutson GA. Anatomic and functional leg-length inequality: A review and recommendation for clinical decision-making. Part II, the functional or unloaded leg-length asymmetry. Chiropractic & Osteopathy 2005, 13:12 doi:10.1186/1746-1340-13-12. d. Woodfield HC, Gerstman BB, Olaisen RH, et al. Interexaminer reliability of supine leg checks for discriminating leg-length inequality. J Manipulative Physiol Ther 2011;34:239-246. “The examiners showed moderate reliability in assessing leg-length inequality at 1/8-in increments and good reliability in determining the presence of a leg-length inequality.” e. Schneider M, Homonai R, Moreland B, Delitto A.J Manipulative Physiol Ther. Interexaminer reliability of the prone leg length analysis procedure. 2007 Sep;30(7):514-21. f. Holt KR, Russell DG, Hoffmann NJ, Bruce BI, Bushell PM, Taylor HH. Interexaminer reliability of a leg length analysis procedure among novice and experienced practitioners. J Manipulative Physiol Ther. 2009 Mar-Apr; 32(3):216-22. doi: 10.1016/j.jmpt.2009.02.009. 6. Thermography Validity & Reliabilty a. Uematsu S. Thermographic imaging of cutaneous sensory segment in patients with peripheral nerve injury. Skin-temperature stability between sides of the body. J Neurosurg. 1985 May;62(5):716-20. b. Voloshyn HH. [The thermal pattern of skin in healthy persons]. Lik Sprava. 2002;(1):20-4. “Based on data from published literature the author has reached the conclusion that the thermal pattern in healthy people has many "hot" and "cold" zones the occurrence of which is due to exposure to a number of anatomical and physiological factors, in the first place,--to particular features of blood supply. However, the distribution of infrared radiation relative to the middle line is in fact symmetrical, the physiological temperature difference does not exceed 0.5 degree C. The knowledge of normal thermal patterns is the necessary condition in interpreting the thermogram in the patient.” c. Zaproudina N1, Varmavuo V, Airaksinen O, Närhi M. Reproducibility of infrared thermography measurements in healthy individuals. Physiol Meas. 2008 Apr;29(4):515-24. doi: 10.1088/0967-3334/29/4/007. Epub 2008 Apr 9. “The results suggest that the IRT technique may represent an objective quantifiable indicator of autonomic disturbances.” d. Plaugher G, Lopes MA, Melch PE, Cremata EE. The inter- and intraexaminer reliability of a paraspinal skin temperature differential instrument. J Manipulative Physiol Ther. 1991 Jul-Aug;14(6):361-7. e. Roy RA, Boucher JP and Comtois AS. Digitized Infrared Segmental Thermometry: time requirements for stable recordings. Journal of Manipulative and Physiological Therapeutics July/August 2006:468e1-10. f. Roy RA, Boucher JP and Comtois AS. Paraspinal cutaneous temperature modification after spinal manipulation at L5. J Manipulative Physiol Ther 2010;33:308-314. g. Owens EF, Hart JF, Donofrio JJ, et al. Paraspinal Skin Temperature PatternsL An Interexaminer and Intraexaminer Reliability Study. Journal of Manipulative and Physiological Therapeutics March/April 2004:155-9. “Intraexaminer and interexaminer reliability of paraspinal thermal scans using the TyTron C-3000 were found to be very high, with ICC values between 0.918 and 0.984. Intraexaminer reliability is slightly higher than interexaminer reliability. Changes seen in thermal scans when properly done are most likely due to actual physiological changes rather than equipment error.” h. McCoy M, Campbell I, Stone P, Fedorchuk C, Wijayawardana S, et al. (2011) Intra-Examiner and Inter-Examiner Reproducibility of Paraspinal Thermography. PLoS ONE 6(2): e16535. doi:10.1371/journal.pone.0016535 “This study revealed excellent intra-examiner and inter-examiner reproducibility of paraspinal thermography using a commercially available unit.” i. Mansholt BA, Vining RD, Long CR, et al. Inter-examiner reliability of the interpretation of paraspinal thermographic pattern analysis. J Can Chiropr Assoc 2015 (Jun); 59 (2): 157-164. “Overall inter-examiner reliability was fair (k=0.43). There was good agreement for identifying full pattern (k=0.73) and fair agreement for adaptation (k=0.55). Poor agreement was noted in partial categories (k=0.05-0.22).” When, NOT Where j. Meeker WC, Gahlinger PM. Neuromusculoskeletal thermography: a valuable diagnostic tool? J Manipulative Physiol Ther. 1986 Dec;9(4):257-66. “In general, the literature reports high sensitivity and negative predictive value, but lower specificity and positive predictive value.” k. Triano JJ, Budgell B, Bagnulo A, et al .Review of methods used by chiropractors to determine the site for applying manipulation. Chiropr Man Therap. 2013 Oct 21;21(1):36. doi: 10.1186/2045-709X-21-36. 7. Blair Case Studies a. Hubbard TA, Kane JD. Chiropractic management of essential tremor and migraine: a case report. Journal of Chiropractic Medicine. 2012;11(2): 121-126. doi:10.1016/j.jcm.2011.10.006. b. Hubbard TA, Crisp CA, Vowles B. Upper cervical chiropractic care for a 25year-old woman with myoclonic seizures. Journal of Chiropractic Medicine. 2010;9(2):90-94. doi:10.1016/j.jcm.2010.03.001. c. Hubbard TA, Crisp CA. Cessation of cyclic vomiting in a 7-year-old girl after upper cervical chiropractic care: a case report. Journal of Chiropractic Medicine. 2010;9(4):179-183. doi:10.1016/j.jcm.2010.07.006. d. Herman CA. Resolution of Low Back Pain in an 8-year-old Following Blair Upper Cervical Chiropractic Care: A Case Report. Journal of Upper Cervical Chiropractic Research;Jul 2016:24-30. e. Burcon MT. Upper Cervical Specific Pattern Analysis Utilizing Paraspinal Thermography, Leg Length Inequality and Heart Rate Variability in Two Patients with Tachycardia. Journal of Upper Cervical Chiropractic Research;Mar 2016:6-12.