DNA Replication and Transcription HElicase unwinds the double helix and separates the two polynucleotide strands DNA REPLICATION Helicanse breaks the hydrogen bonds that exist between complementary base pairs the separated strands will be templates for new complementary strands USES dna polymerase to synthesize new strands occurs during the S phase of the cell cycle requires primer to start replicating occurs during the g1 and g2 phase of the cell cycle does not need a primer The polymerase synthesizes from the separated strand involves binding complementary nucleic acids to DNA If wrong nucleotides are binded there would be errors uses RNA polymerase uses RNA polymerase only some genes are copied strand that isn't transcribed is called sense strand which is idewntical to the RNA sequence with T instead of a U strand that is transcribed is called antisense strand and is complementary to the rna sequence RNA polymerase seperates and synthesises when synthesizing is finished RNA polymerase detaches the double helix is reformed TRANSCRIPTION