THE MOST HEAT RESISTANT XYLANASE GENERATES THE MOST ENERGY MAXIMISE NSP UTILISATION TO IMPROVE FCR AND REDUCE COSTS ECONASE XT INFLUENCES NUTRIENT DIGESTION TO INCREASE USABLE ENERGY •Energy is the most expensive nutrient in the diet – 100 Kcal/Kg currently costs approximately US$10/tonne In broilers, Econase XT: •Using NSPases creates an opportunity for nutritionists and feed producers to maximise energy utilisation from the diet •Reduces digesta viscosity WHY CHOOSE XYLANASE? •Improves nutrient digestibility •Influences intestinal fermentation THE PREBIOTIC EFFECT OF ARABINOXYLAN OLIGOSACCHARIDES (AXOS) •Approximately 45% of the NSP composition of corn and wheat-based diets consists of arabinoxylans, making them the largest NSP component in raw materials •Xylanase is the NSPase that breaks down arabinoxylans into beneficial arabinoxylan oligosaccharides (AXOS), helping to improve animal performance •Econase XT influences intestinal fermentation by producing favourable prebiotic xylo-oligomers in the lower GI •These xylo-oligomers can increase volatile fatty acid production, shift the microbial profile and provide valuable energy for intestinal cells Econase XT attacks and breaks down cell walls B-glucans Others Cellulose Arabinoxylans NSP content in broiler corn-soy diets 2% 24% 27% 47% Release of prebiotic xylo-oligosaccharides NSP content in broiler wheat-soy diets X4/X5 5% 23% 29% 43% NSP content in broiler mixed cereal diets* 9% 25% 23% 43% ECONASE XT – THE XYLANASE THAT DELIVERS OPTIMAL NSP BREAKDOWN FOR IMPROVED ENERGY UTILISATION A beta 1-4 endo-xylanase that optimises the breakdown of NSP, reducing its anti-nutritive effects and improving the energy utilisation of monogastric diets * Wheat and barley diets. FCR: feed conversion ratio NSP: non-starch polysaccharides Altered microbial profile enhances animal performance Fermented by gut microbiota. Growth of lactate and butyrate – producing bacteria Butyrate (a short-chain fatty acid) Increases Antiinflammatory Fuels epithelial cells intestinal epithelial integrity Econase XT helps prime the gut for beneficial bacteria WHY DOES AXOS MATTER? THE ONLY XYLANASE THAT IS INTRINSICALLY THERMOSTABLE XYLANASES DIFFER IN THEIR ABILITY TO BREAK DOWN ARABINOXYLANS • ECONASE XT SURVIVES THE RIGOURS OF THE FEED CONDITIONING PROCESS Different xylanases produce different AXOS profiles • •Xylose (X1) can have a negative effect on animal performance and energy utilisation[Shuttle et al 1991] while X3–X7 can have a positive effect Econase XT Pelleting conditions vary dramatically between feed mills and within the same feed mill •Selecting a xylanase that can withstand the rigors of the feed conditioning process is critical to ensure consistent performance improvements Econase XT is the only xylanase that is intrinsically thermostable Multi R Econase XT remains active throughout the gut, reaching and working where it’s needed 400% X7 X6 Econase XT X5 Multi R X4 200% 400% X7 300% 100% 80% 60% 40% 20% 0% MASH 65°C X6 X2 Potential X5 negative effect X1 80°C 85°C 90°C 95°C 0% JEJUNUM Econase XT Enzyme 2* Enzyme 4* Enzyme 1* Enzyme 3* Enzyme 5* *coated •Econase XT is not hydrolysed by pepsin, surviving enzymatic breakdown in the proventriculus and gizzard Source: AB Vista Econase XT significantly reduces FCR after conditioning at higher temperatures X3 X2 100% Potential negative effect X1 0% 100% 90% 80% 70% 60% 50% 40% X4 DUODENUM Source: AB Vista Trial Report 006 110% X3 ILEUM Conditioning temperature -200% -100% X2 75°C X4 200% -100% X1 - Potential negative effect 70°C 80°C 85°C 90°C Conditioning temperature X5 X6 X7 Source: AB Vista Control Econase XT Multi R Bodyweight corrected FCR (g:g) Xylo-oligosaccharides production after 1h incubation (relative to the ∑X3-X7 by the competitor enzyme) 100% GIZZARD X3 Xylanase activity Xylo-oligosaccharides production after 1h incubation (relative to the ∑X3-X7 by the competitor enzyme) 300% Residual activity (vs mash feed) 120% 1.65 1.60 1.55 1.50 1.45 1.40 1.35 1.30 1.25 1.20 80°C 85°C 90°C Conditioning temperature Xylanase B Source: AB Vista Trial Report 208 -200% Econase XT has been shown to produce beneficial types of AXOS for optimal performance Econase XT was shown to give the largest benefit in FCR vs competitor products ECONASE XT IS PROVEN TO BOOST POULTRY PERFORMANCE ECONASE XT IS SIMPLE TO MEASURE AND DETECT Econase XT is the optimal xylanase for maximising feed utilisation. Analysis of Econase XT is easy and can be measured across a range of feeds. This helps to ensure that the full benefits of using Econase XT are realised. FIVE PROVEN BENEFITS IN POULTRY Reduces FCR in broiler corn and wheat diets a +2.4% b 0 30 20 0 200 400 600 Variation of Weight vs Average (g) (where 0=average weight) Econase XT 120% 110% 90% 80% Egg mass (g/hen/day) Control Source: AB Vista 2.20a 100% 57.2a 5% BXU: birch xylan units Only the active enzyme is detected QUANTIPLATE Improves performance in laying hens 54.5b 10% Control • 16000 Source: AB Vista Improvement over control diet Frequency (%) 15% 0 No lab expertise required 25 5. 20% -200 • b 35 Source: AB Vista Note: Data from a total of 8 trials 25% -400 Reliable confirmation in the feed mill within 5 minutes BXU/Kg Increases broiler uniformity 0% -600 • 40 BXU/Kg 4. A qualitative test that detects the presence of Econase XT in feed a 45 16000 Source: AB Vista Note: Data from a total of 8 trials • Reduces litter moisture by up to 15% 3. Litter moisture corrected for density (%) Metabolisable energy (%) 2. Increases the metabolisable energy of broiler diets 2.32b 1. QUICKSTIX FCR (g:g) Econase XT Source: AB Vista Trial Report 406 Numbers represent absolute values for performance variables measured • A quantitative test that measures the activity of Econase XT in feed • Quick and easy to conduct, reliable results within 4 hours • Lab equipment required • Only the active enzyme is detected Optimal NSP breakdown to deliver FCR and cost reduction The only intrinsically thermostable xylanase up to 95oC MAXIMISE DIETARY ENERGY UTILISATION WITH ECONASE XT Proven results in poultry and swine Effective across a wide range of feed ingredients Easily detected and measured in feed info@abvista.com www.abvista.com www.abvista.com