UNIT 5: GENETIC BASIS OF LIFE REVIEW Part 1: DNA Structure 2. A nucleotide is made of three parts: a _________________________ group, a five carbon _________________________, and a _________________________ base. 3. In a single strand of DNA, the phosphate of one nucleotide binds to the _________________________ of the next. 5. There are four different variations of these monomers (four different bases), what are the names of those bases? a. b. c. d. 6. These bases are of two different types of molecules: purines and pyrimidines. Purines have _______________________ ring(s) in their structure, and pyrimidines have _______________________ ring(s) in their structure. UNIT 5: GENETIC BASIS OF LIFE REVIEW 7. The two bases that are purines are: a. _______________________________ b. _______________________________ 8. The three bases that are pyrimidines are: a. ______________________ b. ____________________ c. ____________________ 9. In the image below, color the purines blue and the pyrimidines orange 10. In a strand of DNA, if the percentage of thymine is 30%, what would the percentage of cytosine in the same DNA strand be? _________________________. 11. What types of bonds connect the bases to each other? 12. Write the complementary sequence to the following DNA strand Strand 1 A G C T T A Strand 2 Part 2: DNA Replication 13. Number the steps of DNA replication in the correct order (1, 2, 3): _____ Daughter strands are formed using complementary base pairing. _____ DNA unwinds _____ The DNA of the daughter strand rebonds with its parent strand. _____ RNA primer is added to 5’ end 14. Why is DNA replication called “semi-conservative”? G C C UNIT 5: GENETIC BASIS OF LIFE REVIEW 15. What enzymes are involved in the following steps of DNA replication? a. b. c. d. e. Adds RNA primers to growing end of DNA_________________________________ Unwinds and unzips the parent strand _____________________________________ Removes RNA primers from growing end of DNA ___________________________ Adds new nitrogenous bases to growing end of DNA _______________________ Zips the new DNA together ______________________________________________ 17. Complete the diagram below that models DNA replication. Then label the diagram with the components and activities of DNA replication. UNIT 5: GENETIC BASIS OF LIFE REVIEW Part 3: RNA and Protein Synthesis 18. Make some comparisons between the nucleic acids DNA and RNA: DNA 5- carbon sugar used Adenine base pairs with # of strands Cytosine base pairs with # of types of molecule Found where in the cell? 19. Describe the role of the following types of RNA: mRNA: tRNA: rRNA: 20. Define the difference between transcription and translation below: 21. Complete the following protein synthesis below RNA UNIT 5: GENETIC BASIS OF LIFE REVIEW 22. Identify the components of protein synthesis and the activities that happen. Part 4: Rapid Fire! 1. Why is the nucleus called the "control center" of the cell? 2. What is a gene? 3. Where in the cell are chromosomes located? 4. DNA can be found in what organelles? 5. What two scientists established the structure of DNA? 6. Replication is called “semi-conservative” because half of the original strand is 7. What are the sides of the DNA ladder made of? 8. What three parts make up a single nucleotide: 9. What are the 4 bases that make up the rungs of the DNA ladder? 10. What sugar is found in DNA? In RNA? UNIT 5: GENETIC BASIS OF LIFE REVIEW 11. How do the bases bond together? A bonds with _____ G bonds with _______ 12. Why is RNA necessary to act as a messenger? 13. Proteins are made where in the cell? 14. How is RNA different from DNA? (list 3 things) 15. The process of copying DNA is called 16. What is the shape of DNA? 17. Proteins are made from what subunits? 18. Three bases found on mRNA are called a Part 5: Concept Maps Use the terms to create concept maps of the three processes discussed in this unit. How do the relate to each other? How do these processes relate to our major themes of Biology: Structure and Function, Homeostasis, Evolution and Systems? DNA Replication Transcription Translation Antiparallel Base pairing Deoxyribose Exonuclease Enzymes Helicase Lagging strand Leading strand Ligase Phosphate Polymerase Primase Nitrogen bases Nucleotide Semiconservative DNA Nucleus mRNA Uracil Gene Base pairing Anticodon Amino Acid Codon Cytoplasm Endoplasmic Reticulum Golgi Apparatus mRNA Polypeptide Chain tRNA Ribosome rRNA Vesicle UNIT 5: GENETIC BASIS OF LIFE REVIEW