Test: Chapter 3 November 2, 2009 Name: __________________________ Section A: True or False Indicate whether the sentence or statement is true or false. ___ 1. In animal cells, the separation of new cells produced by mitosis is accomplished by a cell plate that forms between the two new nuclear masses. ___ 2. In general, cancer cells divide at slower rates than normal cells. ___ 3. Cancer cells lack the ability to differentiate. ___ 4. Meiosis is a process by which gametes are formed. ___ 5. In humans, the haploid number of chromosomes is 46 and the diploid chromosome number is 23. ___ 6. Chromosomes that are not sex chromosomes are referred to as autosomes. ___ 7. Down syndrome is an example of a non-disjunction disorder. ___ 8. Klinefelter syndrome is an example of trisomy. ___ 9. During interphase, cells go through two periods of growth. ___ 10. There is nuclear replication between Meiosis I and Meiosis II. ___ 11. Two sister chromatids are considered to be one chromosome. ___ 12. Spermatogenesis begins at puberty for men and ends by the time they are 60 years old. Section B: Multiple Choice Identify the letter of the choice that best completes the statement or answers the question. 1. If one of two mewly formed daughter cells has one extra chromosome, and the other daughter cell has one less, the problem in the preceding mitotic division probably occurred at a. Prophase b. Metaphase c. Anaphase d. Telophase e. Cytokinesis 2. The proper sequence of mitosis is: a. Prophase, anaphase, metaphase, telophase b. Prophases, telophase, anaphase, metaphase c. Metaphase, prophase, anaphase, telophase d. Telophase, prophase, metaphase, anaphase e. Prophase, metaphase, anaphase, telophase 3. What is the correct sequence of the following events that occur in mitosis? 1. The cytoplasm and organelles are divided between the daughter cells. 2. The nuclear membrane reappear. 3. The centromeres splits. 4. The chromosomes condense and the nuclear membrane disappears. 5. The chromosomes are pulled to the poles of the cell. 6. The chromosomes line up on the equatorial plate. a. 2,1,3,6,5,4 b. 1,4,3,5,6,2 c. 4,3,6,5,1,2 d. 4,6,3,5,2,1 e. 4,6,3,2,5,1 4. If a cell with 36 chromosomes undergoes mitosis, each daughter cell will have a. 36 chromosomes b. 72 chromosomes c. 18 chromosomes d. 9 chromosomes e. 6 chromosomes 5. Which cells in the human body have a diploid number of 46 chromosomes in their nuclei? a. All cells b. Only the reproductive cells c. Only cells that are produced by meiosis d. Only zygotes e. Only cells that are produced by mitosis 6. Which is the result of meiosis? a. Chromosome number is reduced to one-half the original number. b. New combinations of genes are produced when crossing over occurs. c. Maternal and paternal chromosomes are mixed when homologous chromosomes separate independently. d. Genetic variation is maintained within species. e. All of these choices are results of meiosis. 7. Classify the following statements: This type of nuclear division helps maintain the number of chromosomes from generation to generation of offspring. a. Mitosis b. Meiosis c. Fertilization d. Neither mitosis or meiosis e. Both mitosis and meiosis. 8. If a human zygote has an X and a Y chromosome, it will normally produce a a. Male b. Female c. Sterile male d. Lethal characteristic e. Sterile female 9. Cloning of animals can only be accomplished by using the nuclear material from a. Embryonic cells b. Undifferentiated adult cells c. Differentiated adult cells d. All of the above choices may be used to clone animals. e. None of the above as it is not possible to clone animals. 10. An individual with Turner syndrome will have this condition as a result of having a. 47 chromosomes b. 23 chromosomes c. 45 chromosomes d. 22 chromosomes e. 46 chromosomes Section C: Short Answer 11. Why is it that cells divide rather than increase in size? 2 marks 12. Explain why sexual reproduction promotes variation and list the three ways this variation is achieved. 4 marks 13. The diagram below shows a cell with 50 chromosomes undergoing meiosis. a. How many chromosomes would you expect to find in each cell at stage B? 1 mark b. In which stage(s), would you expect to find a cell with a diploid chromosome number? 1 mark c. If non-disjunction occurred during meiosis I, how many chromosomes would you expect to find in stage C in: gamete 1:__________ gamete 2:__________ gamete 3:__________ gamete 4:__________ 2 marks d. If non-disjunction occurred during meiosis II, how many chromosomes would you expect to find in stage C in: gamete 1:_________ gamete 2:__________ gamete 3:_________ gamete 4:__________ 2 marks 14. Explain why the formation of calluses on the hands provides evidence that cell division can be stimulated by cell damage? 2 marks 15. Explain why farm crops propagated from cuttings of other plants are so similar and explain why farmers find this beneficial. 2 marks 16. What is an enucleated cell and what role does it play in cloning? 2 marks Section D: Definitions From the following list of 10 terms choose 5 to define. 2 marks each, total 10 marks autosomes chromatid crossing over homologous chromosomes karyotype polar bodies Down syndrome trisomy gametogenesis zygote