Medications Cold symptoms ● Antihistamines (H1 blockers) ○ 1st generation ■ diphenhydramine ○ 2nd generation ■ Loratidine ● Decongestants (nasal) ○ Oxymetazoline ○ Pseudoephedrine (can decrease effect of beta blockers) ○ Phenylephrine ○ tetrahydrozoline ● Intranasal glucocorticoids (steroids) ○ Fluticasone ○ Beclomethasone ○ Flunisolide ○ Budesonide ○ Mometasone ○ Triamcinolone ● Antitussives ○ Dextromethorphan* ○ Guaifenesin ○ Codeine ○ Benzonatate ● Expectorants ○ Guaifenesin ○ Dextromethorphan — Sinusitis ● Rest, acetaminophen, fluids, systemic/nasal decongestants ● Antibiotics in severe cases Acute pharyngitis ● If streptococcal, antibiotics ● Acetaminophen, lozenges (candy), fluid, saline gargles COPD: asthma ● Bronchodilators ○ Sympathomimetics ■ Epinephrine (A1, B1, B2) ■ Atropine (B2) ○ Parasympatholytics ■ Tiotropium Bromide (spiriva) ○ Methylxanthines ■ Theophylline ● Glucocorticoids (steroids) ○ “-sones/-lones” ○ MDI inhaler, tablet, IV ● Leukotrienes modifiers ○ Montelukast (singulair) ● Cromolyn — Gastrointestinal disorders Vomiting ● Antiemetic ○ Nonprescription ■ 1st generation antihistamines: ● Bismuth subsalicylate ● Meclizine hydrochloride ● Dimenhydrinate ○ Prescription ■ Antihistamines & Anticholinergic ● Antihistamine: hydroxyzine (atarax) ○ Hydroxyzine can also be used for motion sickness, anxiety, vertigo ● Anticholinergic: scopolamine ■ Dopamine antagonists ● Phenothiazines ○ Promethazine (phenergan) <!> ○ Prochlorperazine (compazine) ● Butyrophenones ○ Droperidol ● Benzodiazepine ○ Lorazepam ■ Serotonin antagonists ● Odansetron ● Granisetron ● Dolasetron ■ Benzodiazepines (esp. For cancer pts before chemo) ■ Glucocorticoids ● Dexamethasone ● Methylprednisolone ■ Cannabinoids ● Dronabinol <!> ■ Miscellaneous ● Metoclopramide ● Trimethobenzamide Diarrhea ● Antidiarrheals ○ Opiates and opiate related agents ■ Diphenoxylate ■ Difenoxin ■ Loperamide ○ Adsorbents ○ miscs. Constipation ● Laxatives ○ Osmotic (saline) ■ Lactulose ■ Magnesium citrate ■ Polyethylene glycol (PEG) 3350 ○ Stimulants (irritants) ■ Bisacodyl ■ Senna ○ Bulk-forming ■ Polycarbophil ■ Polyethylene glycol ■ Methylcellulose ■ psyllium ○ Emollient (stool softeners) ■ Docusate calcium ■ Docusate sodium Poisoning ● Emetics — Peptic ulcers ● Antacids ○ Sodium bicarbonate ○ Calcium carbonate ○ Magnesium hydroxide ○ Aluminum hydroxide ● H2 blockers ○ Cimetidine ○ Famotidine ○ Nizatidine ● Proton Pump inhibitors ○ Omeprazole ○ Lansoprazole ● Pepsin inhibitors ○ Sucralfate ● Prostaglandin analogue ○ Misoprostol