BIOLOGY 1113 – ENERGY TRANSFORMATION AND DEVELOPMENT Autumn 2018 Lectures: Mon/Wed/Fri 9:10 – 10:05 AM, Independence Hall 100 INSTRUCTOR Dr. Eric Danhart (danhart.1@osu.edu) 210 Jennings Hall Office Hours: Wednesday 10:30am – 12:30pm and by appointment COURSE COORDINATOR Jonathan Horn (horn.179@osu.edu), 292-3929 255F Jennings Hall Office hours: By appointment HEAD TA Dr. Ryan Bell (bell.586@osu.edu) 210 Jennings Hall Office hours: Thursday 11:00am – 12:00pm and by appointment PROGRAM ASSISTANT TBA 240A Jennings Hall Office hours: By appointment Description: Biology 1113 is a course that, together with Biology 1114, is designed to give the student an in-depth experience in the biological sciences. Science majors, including many health professionals, are the intended audience. The sequence will meet your General Education Curriculum in the Natural Sciences Prerequisites (or concurrent): Chem 1110, 1210, 1610, or 1910H, or permission of course coordinator (in rare cases) COURSE MATERIALS Lecture Textbook (required): Freeman S, Quillin K, Allison L, Black M, Podgorski G, Taylor E, and Carmichael J. (2015) Biological Science, 6th edition. Pearson Higher Education, Hoboken. ISBN (Hardback + Mastering Biology): 978-0-134-57782-1 ISBN (Loose leaf + Mastering Biology): 978-0-134-52807-6 ISBN (eText only + Mastering Biology): 978-0-134-29478-0 Laboratory Manual (required): Faculty and Staff of the Center for Life Sciences Education, The Ohio State University. (20182019) Biology 1113/1113H Laboratory Manual (Plymouth, Michigan: Hayden-McNeil Publishing). ISBN (2018-2019 edition): 978-1-533-90264-1 Handouts: Many handouts will be provided in the course, all of which will be posted in digital format in the Content section of Carmen, which can be accessed online at www.carmen.osu.edu. BIOLOGY 1113 LEARNING OUTCOMES Upon course completion, successful students will be able to…. 1. The Chemistry of Life a. Identify examples and list characteristics and general functions of the major classes of biological macromolecules (carbohydrates, lipids, proteins, nucleic acids). 2. The Cell a. Explain the activities in the cell by relating cellular structure and cellular function. b. Explain the mechanisms and structures involved in mitotic and meiotic cell division and explain the different roles for and consequences of each. c. Explain the forms of energy utilized in biological systems and the laws of thermodynamics that govern them. d. Explain the energy transformations involved in fermentation, cellular respiration, and photosynthesis (including orderly chemical transformations, the relevance of redox reactions, and electron/proton transport). e. Describe the nature and function of enzymes and describe major mechanisms used to control their activity. f. Describe the cellular response to its environment (e.g. membrane transport, signal transduction). g. Describe how the loss/failure of cellular control mechanisms can cause cancer. 3. Genetics a. Explain the transfer and modification of heritable traits from parents to offspring. b. Describe the nature and expression of heritable information at the molecular level, including DNA replication, DNA repair, transcription, protein synthesis. c. Apply Mendelian genetics to solve monohybrid and dihybrid crosses. d. Identify examples of non-Mendelian patterns of inheritance. e. Explain how genetic expression is controlled in prokaryotes and eukaryotes. f. Explain cellular reproduction, growth, and differentiation in the context of organismal development. g. Describe characteristics of viruses and bacteria (e.g., life history genome type and content, exchange of genetic material). h. Describe the experimental basis and select applications of recombinant DNA technology. 4. Nature of biological science and society a. Describe the development and evaluation of scientific explanations of natural phenomena. b. Apply biological concepts in the assessment of contemporary issues. c. Explain how evolution accounts for the unity and diversity of life. GEC Natural Science Learning Objectives Courses in natural sciences foster an understanding of the principles, theories and methods of modern science, the relationship between science and technology, and the effects of science and technology on the environment. 1. Students understand the basic facts, principles, theories, and methods of modern science. 2. Students understand key events in the development of science and recognize that science is an evolving body of knowledge. 3. Students describe the inter-dependence of scientific and technological developments. 4. Students recognize social and philosophical implications of scientific discoveries and understand the potential of science and technology to address problems of the contemporary world. In Biology 1113, Biological Sciences majors meet the GEC Natural Science Learning Objectives in multiple ways. The course, in conjunction with Biology 1114, is an in-depth study of the laws, structures, and interrelationships within the biological universe. Students gain an understanding of the foundations of modern biology by studying cell structure and function, bioenergetics, genetics, and early animal development. In the laboratory activities, students not only apply the biological concepts introduced in lecture, but also learn scientific reasoning and methods. Through the study of the history and key discoveries in biology, Biology 1113 students learn the details of the interrelationship between technology and scientific methods in the modern investigative study of biology and gain an appreciation of the social and philosophical ramifications of our knowledge of biology and biological discoveries. COURSE TECHNOLOGIES: We will use the following tools to help you learn in this course. • Top Hat: We will use TopHat (a classroom response system - see www.tophat.com) during lecture to provide students with opportunities to be active participants. You will be able to submit answers to in-class questions using smartphones, tablets, laptops, or via text message. See our Carmen page for a link to the Student Quick Start Guide, which outlines how you will register for a Top Hat account. The guide will also help to get you up and running on the system. • Mastering Biology: Mastering Biology is an online tool that accompanies our Freeman textbook and that provides you with a great resource for succeeding in the course. You will access homework assignments and supplemental questions and quizzes through “Mastering.” You will need to register for Mastering Biology during the first week of the term. Instructions for registering and logging in can be found on Carmen (Carmen - Pages - Guide to Mastering Biology). Once your Mastering Biology account is activated, select the “Mylab and Mastering” tab on the course navigation menu to access materials. GRADING AND COURSE POINTS: The overall point distribution for the course is as follows: Graded Items Lecture Points Midterm Exam 1 100 Midterm Exam 2 100 Midterm Exam 3 100 Final Exam 150 Mastering Biology Lecture Preparation Assignments 150 Top Hat 75 In-class Activities 100 Questionnaires and Surveys 25 Lab Points Lab Safety 5 Microscope Proficiency 3 Pre-lab assignments 26 Lab exercises/activities (8 Lab Assignments @ 10-30 points) 125 Lab quizzes (3 Quizzes @ 10 points) 30 Poster Project (checkpoints + completed poster) 40 Lab Final 45 Overall lab performance (Attendance, Discussion, Group Participation, Clean-up) 20 Subtotals 294 800 TOTAL 1094 Grade Scheme: Your final grade will be based on the percentage of the 1094 points that you earn during the semester, as indicated below. Please note that we do not grade the course on a curve and Carmen does not round averages up to the next nearest percentage point, so 92.11% and 92.97% both earn the grade of A-. NOTE: The grading scale is tentative and is subject to adjustments.) % Grade 93-100 A 90-92 A- % Grade 87-89 B+ 83-86 B % Grade 80-82 B77-79 C+ % Grade 73-76 C 70-72 C- % Grade 67-69 D+ 60-66 D % Grade 59 and below E GRADED LECTURE ITEM DESCRIPTIONS: Exams (450 points): There will be three midterm exams administered during the normal lecture period, in the normal lecture room, on the dates listed on the lecture syllabus. Questions will be mainly multiple choice format, with responses entered via scantron, with the possibility of some short answer style. Material will be drawn from the lectures, lecture activities, and assigned readings. The final exam will be held in the normal lecture room on Monday December 10th from 10:00 - 11:45 AM. The final exam will be cumulative, with a focus on material following the third midterm exam. Please contact our Program Assistant if you have questions about exam scores or if you believe there is an issue with your scantron. Mastering Biology Lecture Preparation Assignments (150 points): Before each lecture, students are expected to skim the associated textbook sections and complete Mastering Biology pre-lecture assignments. Pre-lecture assignments will be made available one week before the associated lecture and will close at 9:00am on the day of the lecture. These assignments are designed to introduce concepts and topics that will help facilitate more efficient and effective learning during the lecture. Mastering Biology Dynamic Study Modules: Following the completion of a chapter of the textbook in lecture, Dynamic Study Module (DSM) assignments will become available in Mastering Biology, which are designed to reinforce material covered in lecture. DSMs will not be graded for credit but can be used to earn points back from missed Top Hat or In-class Activities (described below). DSMs may be completed at any time, but in order to earn points, they must be completed by the posted due date, typically one week following the associated lecture. Top Hat (75 points): Top Hat questions will be administered in nearly every lecture throughout the semester. Questions will typically be worth 1 point each, graded for participation, correctness, or a combination of both. Points will be updated on Carmen prior to each exam. Proper registration is required prior to the third lecture of the semester (Aug 27). (This means that you will begin to earn your Top Hat points during week two.) Points will not be applied retroactively. More than 75 total questions will be administered, providing some leeway in earning the total points. As such, no make-up opportunities will be available for missed lectures or nonfunctional technology. In-Class Activities (100 points): Our course will take advantage of a number of active learning methods throughout the term. Active learning can be thought of as any behavior that results in a learner taking an active role in the learning process (i.e. not passively listening to the instructor). Studies have now consistently demonstrated that learning improves when these approaches are embraced, and we will adopt these strategies and make extensive use of them in this course. Typically, our in-class activities will involve students working in pairs or groups to answer questions or solve problems associated with the topic of the day. Selected activities will be collected and graded for points (5-10 points each). Be sure to attend lecture regularly! As these are specifically in-class activities, no makeups will be available. However, with the understanding that occasional absences are both inevitable and unavoidable, more than the required 100 points will be made available during the term to accommodate situations in which a lecture must be missed. Please notify your TA and Dr. Danhart in the case of an extreme or unusual situation in which you anticipate multiple absences from class. Questionnaires and Surveys (25 points): A total of three different questionnaires and surveys will be administered in the course for course credit. These include the Test of Scientific Literacy Skills (TOSLS) and the Perceptions of Learning Outcomes Worksheet (PLOW), each of which will be assigned twice during the term (4 total assignments at 5 points each). In addition, we will complete the Student Assessment of Learning Gains (SALG) near the end of the term for an additional 5 points. LECTURE SCHEDULE AND ASSOCIATED TEXTBOOK SECTIONS: Date Lecture 8/22 8/24 8/27 8/29 8/31 9/3 9/5 9/7 9/10 9/12 9/14 9/17 9/19 9/21 9/24 9/26 9/28 10/1 10/3 10/5 10/8 10/10 10/12 10/15 10/17 10/19 10/22 10/24 10/26 10/29 10/31 11/2 11/5 11/7 11/9 11/12 11/14 11/16 11/19 11/21 11/23 11/26 11/28 11/30 12/3 12/5 1 2 3 4 5 12/10 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 Topic Introduction/Expectations/Process of Science Properties of Life Water and the Chemistry of Life Chemical Energy and Chemical Evolution Protein Structure and Function Labor Day (no class) Nucleic Acid Structure and Function Carbohydrate Structure and Function Lipids and Membranes Catch-up/ In-class Activity Tour of the Cell Cell Systems Cell-cell Interactions Thermodynamics/ Exam Review Exam 1 (Covers Lectures 1-12; Chapters 1-7, 11) Enzymes Cellular Respiration (Part 1) Cellular Respiration (Part 2) and Fermentation Metacognition (Guest Lecture by Dr. Dave Sovic) Photosynthesis (Part 1) Photosynthesis (Part 2) Catch-up/ In-class Activity Autumn Break (no class) The Cell Cycle and Mitosis Meiosis Mendel and the Gene/ Exam Review Exam 2 (Covers Lectures 13-23; Chapters 8-10, 12-13) Morgan and the Gene Exceptions and Human Inheritance DNA Replication Telomeres and DNA Repair The Central Dogma Transcription and RNA Processing Translation Catch-up/ In-class Activity Veteran’s Day Observed (no class) Control of Gene Expression in Bacteria Control of Gene Expression in Eukarya/ Exam Review Exam 3 (Covers Lectures 24-35; Chapters 14-19) Textbook Sections 1.1 – 1.5 2.1 – 2.2 2.3 – 2.5 3.1 – 3.4 4.1 – 4.4 5.1 – 5.3 6.1 – 6.4 7.1 – 7.3 7.4 – 7.6 11.1 – 11.4 8.1 – 8.2 8.3 – 8.5 9.1 – 9.4 9.5 – 9.6 10.1 – 10.3 10.4 12.1 – 12.3 13.1 – 13.4 14.1 – 14.3 14.4 – 14.5 14.5 – 14.6 15.1 – 15.3 15.4 – 15.5 16.1 – 16.4 17.1 – 17.2 17.3 – 17.5 18.1 – 18.5 19.1 – 19.5 Thanksgiving Break (no class) 37 38 39 40 41 Cancer Recombinant DNA Technology and PCR Biotechnology Organismal Development Wrap-up/ Exam Review Final Exam (10:00 – 11:45 AM) (Cumulative, with a focus on Lectures 37-41; Chapters 20-21) 12.4, 19.6 20.1 – 20.2 20.3 – 20.5 21.1 – 21.4 CLSE POLICIES: Grade Disputes: It is the student’s responsibility to follow his/her progress in the course throughout the semester. Questions about grading mistakes or grades that are missing should be directed to your TA within one week after the posting of graded class material to Carmen. Grade disputes brought to the attention of your TA or the Course Coordinator more than ten (10) class days after they have been posted will not be considered. Section Changes: All requests to change sections, add the course after the first Friday, special permission to enroll, etc. are handled by the Course Coordinator, Jon Horn. Due to the need to keep up-to-minute availability of seats in each recitation, the lecturer and TA are unable to sign any permission forms. Issue Resolution: The CLSE believes that student concerns are usually most effectively addressed by the staff closest to the situation. Therefore, students are ordinarily expected to address issues or concerns with their TA or instructor first. If the issue cannot be resolved, or for some reason you feel that you absolutely cannot address your concern with the TA or instructor, please feel free to contact the Course Coordinator or Assistant Director Matt Misicka (misicka.1@osu.edu). Copyrighted Class Materials ©: The instructor’s lectures and course materials, including power point presentations, tests, outlines, and similar materials, are protected by copyright. You may take notes and make copies of course materials for your own use. You may not and may not allow others to reproduce or distribute lecture notes and course materials publicly whether or not a fee is charged without the express written consent of the instructor. Lecture Exam Makeups Policy: If you are too ill to take an exam or must miss for another legitimate reason (the funeral of a family member, for example), you must contact the Course Coordinator, Jon Horn, within 24 hours of the exam. Make up exams will be given only to students who produce, at the make up or before, documentation of a legitimate reason (at the time of the absence) for missing a quiz or exam. Medical excuses will be considered only if you have been treated by a medical professional on the day of the exam (excuses from the student health center website will not be accepted). The exam must be made up within one week of when it was given. If you anticipate having to miss an exam due to attendance at a university sanctioned event or other qualifying conflict, you must contact the Course Coordinator at least one week in advance of the exam and supply written documentation signed by an appropriate official. Valid excuses are limited to problems that are beyond the student's control, such as military duty, intercollegiate athletic or academic activities, funerals, etc. Written documentation of these activities must be provided. Students arriving late to an exam may take the exam in the time remaining. Once someone has completed the exam and left the room, however, students arriving late may take the exam in the time remaining but with a 25% penalty. Lack of transportation, loss of electricity, travel plans, etc. are not considered valid excuses. If suitable documentation is presented a make-up exam will be given. The format of makeup exams is at the discretion of the instructor. UNIVERSITY POLICIES: Academic Misconduct: Students may work in cooperative groups, however each student is responsible for completing assignments in his/her own words. It is the responsibility of the Committee on Academic Misconduct to investigate or establish procedures for the investigation of all reported cases of student academic misconduct. The term “academic misconduct” includes all forms of student academic misconduct wherever committed; illustrated by, but not limited to, cases of plagiarism and dishonest practices in connection with examinations. Instructors shall report all instances of alleged academic misconduct to the committee (Faculty Rule 3335-5-487). For additional information, see the Code of Student Conduct http://studentlife.osu.edu/csc/. Accessibility: The University strives to make all learning experiences as accessible as possible. If you anticipate or experience academic barriers based on your disability (including mental health, chronic or temporary medical conditions), please let the head TA know immediately so options can be privately discussed. To establish reasonable accommodations, we may request that you register with Student Life Disability Services. If you anticipate academic barriers, please make arrangements by the end of the first week to discuss your accommodations. SLDS contact information: slds@osu.edu; 614-2923307; slds.osu.edu; 098 Baker Hall, 113 W. 12th Avenue. Diversity and Inclusion The Center for Life Sciences Education promotes a welcoming and inclusive environment for all students and staff, regardless of race, age, religion, gender, ethnicity, national origin, disability, or sexual orientation. There is no tolerance for hateful speech or actions. All violations of this policy should be reported to the OSU Bias Assessment and Response Team (BART, www.studentaffairs.osu.edu/bias). Sexual Harassment (and Relationship Violence) OSU and the CLSE consider sexual harassment offenses to be unacceptable behaviors that destroy opportunities for learning. While all members of the staff involved in this course have been trained in the OSU sexual harassment policies and procedures, this is not true for all OSU students. The emphasis in this course on informal laboratory and cooperative/collaborative learning techniques can result in situations mistakenly interpreted by some students as a desire to form a relationship outside the confines of the learning goals and activities of this class. Incidents of inappropriate sexual advances can and have resulted from misunderstandings about this issue. As always, all students in this class are expected to behave at all times with mutual respect and responsibility. Please report any concerns about questionable or unwanted behavior to the Course Coordinator, Jonathan Horn. (http://hr.osu.edu/cst/sexualharassment.htm). Safe Ride Service Safe Ride (614-292-3322) is a service provided to university students, faculty, and staff who would like safe transportation across campus. Rides are scheduled on a first-come first-serve basis. Phone lines open at 7pm and rides are available until 3am. For more information and service boundaries, please visit https://dps.osu.edu/safe-ride. LABORATORY GRADING AND POLICIES: Laboratory and Recitation Policy: ATTENDANCE IN LAB/RECITATION IS MANDATORY. Laboratory and recitation are an integral part of course. You may first encounter something in lab before you have it in lecture or vice versa. Students are expected to come prepared to lab having read the experiment in the lab manual that will be presented. Labs do not go in the order presented in the manual- check the schedule at the end of this syllabus. Laboratory Assignments (125 points): Laboratory grading and assignments will be discussed by your TA. Lab exercises generally come from the lab manual and are completed in cooperative groups of 4-5 students. All group members are expected to contribute EQUALLY, and your participation in each exercise will be evaluated by the TA each period. Groups are required to turn in one lab summary on which all group members sign their name. All lab group members will receive the same score for each graded lab assignment IF all members participated equally in the work each day. Assignments are due at the end of the lab period unless otherwise stated in the syllabus or announced by your TA. Graded assignments will typically be returned to you within one week after submission. All lab scores are posted on Carmen. You then have 10 business days in which to check your grade for possible errors in grading or to inquire about a grade not yet posted. Pre-lab assignments (26 points): Pre-lab questions are due on Carmen prior to the start of every lab period. Pre-lab questions submitted after the start of the lab period will receive 0 points. Pre-lab questions should be answered by using your lab manual and any provided materials. Reading the exercise and answering the questions thoroughly will help you to be efficient and effective in lab. Lab Quizzes (30 points): The lab quizzes will cover the material from the preceding labs, information from recitation, and information that you should have read for the current lab. Quizzes will occur at the beginning of the lab period. If you are late to lab, you will have the time remaining to take the quiz; you will not be given extra time and you will not be given a make-up quiz. Quiz format will be multiplechoice and short answer. Quizzes are taken individually, not as a group. The schedule for these quizzes as well as the material that each will cover are listed on the lab/recitation schedule. Poster Project (40 points): A major goal of this course is to demonstrate the relevance of biology to society today. To that end, students will work in groups to design and present a poster. This is not simply a research poster, but a project intended to create discussion and exploration around current important biological topics in Biology 1113 and in society, understand how scientists approach a problem such as a pathogenic disease (and how that may change with advancing technologies), and provide examples of how science and technology can be used to address problems of the contemporary world. The poster project and associated checkpoint assignments are explained in detail in the Research Poster Guidelines document on Carmen and will be discussed by your TA in lab. Lab Final (45 points): The lab final exam is comprehensive and consists of multiple-choice questions. BIOLOGY 1113 LABORATORY POLICY GENERAL INFORMATION: Attend only the class section in which you are enrolled. TAs cannot enroll you into a different section. If you would like to change your section after the first Friday of the semester (supported by a reasonable impetus for the switch), contact the Course Coordinator, Jon Horn. Laboratory Safety: Eating, drinking, smoking, and chewing tobacco is prohibited in lab. Open-toe shoes and flip-flops cannot be worn in the lab room. Treat all chemicals with respect and care. Please be cautious when using them and use any safety equipment provided. There currently is one procedure in the photosynthesis lab that pregnant women should avoid; your instructor will announce this in lab. If you are pregnant, suspect you may be pregnant at that time, or are particularly sensitive to chemicals, please notify your instructor before this exercise is performed. A safety review will constitute a part of the initial class discussion, and a summary of this review must be handed in by EACH student in the class. The minimum grade required on the Safety Review in order to be allowed to continue in lab is 80%. Upon achieving this grade, each individual will sign a form that indicates that he/she understands the laboratory safety rules. Late Lab Assignments: Assignments are due at the end of the lab period unless otherwise stated in the syllabus or announced. Any lab assignment turned in late must be placed in your TA’s mailbox in room 247 Jennings between the hours of 8:00 A.M. and 5:00 P.M. weekdays. You are required to record your assignment in the assignment log notebook and time-stamp your assignment with the time stamp machine, both located just inside the doorway. Recording and stamping your assignment is for your benefit to make sure your paper is received and gets proper credit. Assignments not recorded and time stamped will be assumed to have been received on the day of pick up. Late assignments will lose 25% of the available points per day; for up to three (3) days after the due date. Assignments will NOT be accepted after more than three days. Missed Labs: If you miss a lab, you must contact your TA within 48 hours. Lab is an integral part of this course. All make up work requires a valid written excuse from a doctor, athletic coach, or other person involved with the absence (preferably before the event occurs if it’s a planned absence). Your TA cannot accept or give any make up work without a written excuse. All make up lab work must be completed and received within one week of the original assignment date (unless very unusual circumstances apply), or else you forfeit all points for that lab. Therefore, it is essential that you contact your TA immediately if you miss a lab, or if you know in advance that you cannot attend lab on a specific date. Anyone who misses three (3) labs/recitations (excuse or unexcused) in a given semester will receive a failing grade for the course. No one will receive a make-up for work/quizzes missed after the third missed period (i.e., from the 4th period missed onward), even if that individual has a valid excuse. Please Note: This is NOT a correspondence course; it is a laboratory course. LAB/RECITATION SCHEDULE: Lab Week Lab Exercise/Topic 8/27 – 8/31 Introduction to General Laboratory Protocol and Safety Review; Exercise 1: Microscope Use 9/3 – 9/7 Exercise 2: Properties of Biological Membranes Assignment details Read Before Lab – Welcome to Biology Lab, Safety Review, and Exercise 1 Due @ beginning – Pre-lab questions Ex. 1 (2 pts; individual) Due @ end – Safety Review (5 pts; individual), Assignment from Ex. 1 (10 pts; group) Microscope Proficiency (3 pts; individual) Read Before Lab – Exercise 2 Due @ beginning – Pre-lab questions Ex. 2 (2 pts; individual) Due @ end – Assignment from Ex. 2 (15 pts; group) NOTE for Monday lab students: Sign up to attend a different lab section for this week. 9/10 – 9/14 Exercise 11: The Scientific Method (Part 1) Read Before Lab – Exercise 11 Due @ beginning – Listen to 1-hour podcast; Read “Selling Soap” article; Pre-lab questions Ex. 11 (5 pts; individual) 9/17 – 9/21 Exercise 11: The Scientific Method (Part 2) Quiz 1 (Safety, Ex. 1, 2, 11) Due @ beginning – Annotated bibliography (5 pts; on Carmen). Bring a laptop if you have one Due @ end – Assignment from Ex. 11 (30 pts; group) Due @ midnight – 1st Poster Project checkpoint on Carmen (1 pt) 9/24 – 9/28 Exercise 4: Photosynthesis (Part 1) Read Before Lab – Exercise 4, Investigation I Due @ beginning – Pre-lab questions Ex. 4, Investigation I (2 pts; individual) Due @ end – Assignment from Ex. 3 (15 pts; group) 10/1 – 10/5 Exercise 4: Photosynthesis (Part 2) Read Before Lab – Exercise 4, Investigations II&III Due @ beginning – Pre-lab questions Ex. 4, Investigation II (2 pts; individual) Due @ end – Assignment from Ex. 4 (15 pts; group) Due @ midnight – 2nd Poster Project checkpoint on Carmen (3 pts) 10/8 – 10/12 No labs (Autumn Break) 10/15 – 10/19 Exercise 6: Mendelian Genetics with Statistical Analysis Quiz 2 (Ex. 11, 4, pre-6) Read Before Lab – Exercise 6 Due @ beginning – Pre-lab questions Ex. 6 (2 pts; individual) Due @ end – Assignment from Ex. 6 (15 pts; group) Due @ midnight – 3rd Poster Project checkpoint on Carmen (3 pts) 10/22 – 10/26 Exercise 8: Molecular Structure of Genes Read Before Lab – Exercise 8; Watson-Crick Nature paper Due @ beginning – Pre-lab questions Ex. 8 (2 pts; individual) Due @ end – Assignment from Ex. 8 (15 pts; group) 10/29 – 11/2 Exercise 10: PCR and Gel-Electrophoresis (Part 1) Read Before Lab – Exercise 10 Due @ beginning – Pre-lab questions Ex. 10 (2 pts; individual) Due @ end – PCR Activity (10 pts; group) 11/5 – 11/9 Poster Presentations Due @ beginning – Completed Poster Project (33 pts); Pre-lab questions Ex. 10 (Investigation III) (2 pts; individual) Due @ end – Assignment from Ex. 10 (15 pts; group) Exercise 10: PCR and Gel-Electrophoresis (Part 2) 11/12 – 11/16 Lab Final Review Quiz 3 (Ex. 6, 8, 10) NOTE for Monday lab students: Sign up to attend a different lab section for this week. 11/19 – 11/23 No Labs 11/26 – 11/30 LAB FINAL (Thanksgiving Break) Cumulative Multiple-choice exam (45 pts)