Uploaded by Farhan Ali

07. Hormonal control of gametogenesis

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4.Hor
monalcont
r
olofgamet
ogenesi
s
I
nt
hi
st
opi
cwewi
l
l
st
udyaboutt
hehor
monal
cont
r
ol
ofhumanr
epr
oduct
i
v
esy
st
em.
4.
1.Mal
er
epr
oduct
i
v
esy
st
em
I
nmal
essper
mat
ogenesi
si
scont
r
ol
l
edbyt
womai
nhor
moneswhi
char
eexpl
ai
ned
bel
ow:
a)
.FSH(
Fol
l
i
cl
est
i
mul
at
i
nghor
mones):
Fol
l
i
cl
est
i
mul
at
i
nghor
monesar
er
el
easedbyant
er
i
orpi
t
ui
t
ar
ygl
andi
nr
esponset
ot
he
Gonadot
r
ophi
nr
el
easi
nghor
mones(
GnRH)ofhy
pot
hal
amus.Thef
unct
i
onsofFSHar
e:
1.Theyst
i
mul
at
et
heger
mi
nal
epi
t
hel
i
um andi
ncr
easet
her
at
eofsper
mat
ogenesi
s.
2.Theyst
i
mul
at
eser
t
ol
i
cel
l
st
ocompl
et
et
hedev
el
opmentofsper
msf
r
om sper
mat
i
ds.
3.Theyal
sost
i
mul
at
eser
t
ol
icel
l
st
or
el
easet
wot
y
pesofpr
ot
ei
nswhi
char
eandr
ogen
bi
ndi
ngpr
ot
ei
nandi
nhi
bi
n.
4.Andr
ogenbi
ndi
ngpr
ot
ei
nbi
ndst
oandr
ogen(
t
est
ost
er
one)sot
hati
t
sconcent
r
at
i
oni
n
semi
ni
f
er
oust
ubul
esr
emai
nhi
ghwhi
chi
nt
ur
ncauset
hegr
owt
handdev
el
opmentof
ger
mi
nal
epi
t
hel
i
um t
of
or
m sper
ms.
5.I
nhi
bi
nhor
monesser
v
est
ocont
r
olt
hesper
mat
ogenesi
satnor
malr
at
e.I
t
ssecr
et
i
on
i
ncr
easewhent
hesper
m counti
shi
ght
oi
nhi
bi
tt
heant
er
i
orpi
t
ui
t
ar
yr
el
easeofFSHand
hy
pot
hal
ami
cr
el
easeofGnRH.I
t
sr
el
easedecl
i
nest
eepl
ywhent
hesper
m countf
al
l
s.
b)
.LH(
Leut
ei
ni
zi
nghor
mones):
Leut
ei
ni
zi
nghor
monesar
eal
sor
el
easedbyant
er
i
orpi
t
ui
t
ar
yi
nr
esponset
oGnRHof
hy
pot
hal
amus.Thesehor
monesst
i
mul
at
est
heLey
di
gcel
l
s(
i
nt
er
st
i
t
i
alcel
l
s)henceal
socal
l
ed
i
nt
er
st
i
t
i
alcel
l
sst
i
mul
at
i
nghor
mones(
I
CSH)
.Ley
di
gcel
l
sonst
i
mul
at
i
onsecr
et
eandr
ogen
(
mal
e sex hor
mones)i
.
e.t
est
ost
er
one whi
ch i
s mai
nl
yr
esponsi
bl
ef
orsecondar
y sex
char
act
er
i
st
i
csatpuber
t
y
.
Puber
t
yi
nmal
es
Thepuber
t
yi
nmal
esi
schar
act
er
i
zedatt
heage1316y
ear
s.Atpuber
t
ysomechanges
i
nt
hehumanbodyoccur
si
nr
esponset
oandr
ogen.Thesechangesi
ncl
ude:
1.Sper
mi
ogenesi
sst
ar
t
si
nt
het
est
es.
2.Secondar
ysexor
gans(
i
ncl
udi
nggl
ands)dev
el
opandbecomef
unct
i
onal
.
3.Voi
cedeepensduet
oenl
ar
gementofv
oi
cebox.
4.Char
act
er
i
st
i
chai
rpat
t
er
nappear
sont
hebodyi
ncl
udi
ngbear
dandhai
ronchest
.
5.Br
oadni
ngofshoul
der
soccur
sandt
hehei
ghti
ncr
ease.
4.
2.Femal
er
epr
oduct
i
v
esy
st
em
I
nf
emal
esoogenesi
si
sal
socont
r
ol
l
edbyt
wohor
monesexpl
ai
nedbel
ow.
a)
.FSH(
Fol
l
i
cl
est
i
mul
at
i
nghor
mones):
I
nf
emal
est
hef
unct
i
onsofFSHi
ncl
ude:
1.Theyst
i
mul
at
ef
ol
l
i
cul
arcel
l
s(
ger
mi
nal
epi
t
hel
i
um)t
ochangei
nt
oGr
af
f
i
anf
ol
l
i
cl
es.
2.Whenf
ol
l
i
cul
arcel
l
sar
est
i
mul
at
edbyFSHt
heyr
el
easeest
r
ogenwhi
chi
sr
esponsi
bl
e
f
orsecondar
ysexchar
act
er
i
st
i
csi
nf
emal
esatpuber
t
y
.
b)
.LH(
Leut
ei
ni
zi
nghor
mones):
Thef
unct
i
onsofLHi
nf
emal
esar
e:
1.Theymai
nt
ai
nt
hecor
pusl
ut
eum af
t
erov
ul
at
i
onoft
heov
um.
2.Cor
pusl
ut
eum i
sconv
er
t
edi
nt
oat
empor
ar
ygl
andwhi
chsecr
et
espr
ogest
er
one.
Puber
t
yi
nf
emal
es
Theper
i
odofpuber
t
yi
nf
emal
esi
s1114y
ear
s.Changesoccur
i
ngi
nt
hebodyof
f
emal
esatpuber
t
yar
e:
1.Oogenesi
sst
ar
t
s.
2.Menst
r
ual
cy
cl
eandov
ul
at
i
onst
ar
t
s.
3.Wi
deni
ngoft
hepel
v
i
c(
hi
p)r
egi
onoccur
sf
ort
hest
r
et
chi
ngofut
er
us.
4.Enl
ar
gementofmammar
ygl
andsoccur
.
5.Accumul
at
i
onoff
at
soccuri
ncer
t
ai
nr
egi
onsoft
hebodyl
i
ket
hi
ghandhi
pr
egi
on.
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