Uploaded by Victor Hugo

QUADRO-APPLICATION-BULLETIN-typical-pharmaceutical-applications-1

advertisement
Quadro® Comil®
Quadro Comil Pharmaceutical Applications
OVERVIEW
DRY GRANULATION
Pharmaceutical companies worldwide are successfully
using the Quadro® Comil® for wet granulation mixes
before drying, sizing after drying, granulating in the
pre-compression stage, homogeneous mixing,
conditioning, and dispersion of pigments in the
manufacture of tablets.
▪ Ribbons from a roller compactor can be size reduced
with a Comil® to granules with optimum particle size
distribution for efficient tableting.
WET GRANULATION
▪ The Comil® is designed to take wet lumpy
granulations and uniformly size them at very high
capacities.
▪ Sizing or de-lumping wet granulations ensure
equally sized granules are introduced into driers,
thus eliminating case hardening and helping
granules to dry uniformly and more rapidly.
▪ Uniform particle size distributions prevent fines and
potential un-even die filling or sticking at the
punches during tableting.
TABLET/CAPSULE RECLAIM
▪ “Off spec” tablets can be size reduced for reclaim
purposes.
INGREDIENT CONDITIONING
▪ Ideal for a broad range of de-lumping, mixing,
finishing and milling.
▪ Lump-free homogeneous dry ingredient blending.
▪ Low heat build-up and precise screen size ensure
complete dispersion, at desired particle size.
COMIL BENEFITS
Low dust
Low noise
Low heat
Fewer fines
Short changeover times
High capacities
Easy, fast cleaning
▪ “Off spec” capsules can be broken into large pieces
allowing for easy separation of powder from the
gelatin pieces.
The overdriven Comil
APPLICATION BULLETIN
Chem01- metal pigment
www.quadro-mpt.com
Download