Perioperative Nursing Care Types of Surgery Purpose Inpatient Ambulatory: outpatient, one-day (same-day surgery), short-stay unit Extent of surgery Simple Radical Diagnostic: to confirm or establish diagnosis Corrective: excision or removal of diseased body part Perioperative Phases: the importance of providing continuity of care for surgical Reconstructive: restore function or appearance to traumatized of malfunctioning patient before, during, and following surgery tissues Ablative: removes a diseased body parts Interprofessional Team Palliative: relieves or reduces pain or symptoms of a disease; it does not cure Physicians/Surgeons: Internist, endocrinologist, cardiologist, respirologist, Transplant: replaces malfunctioning structures anaesthetist Cosmetic: performed to improve personal appearance Nurses Receiving units (s) – RN, RPN Nurse specialists (ET) Urgency OT, PT, SW, Pharmacy, Speech Language, Dietician, Pastoral Care Emergency: performed immediately to preserve function or the life of the client Child Life Worker Community Partners [Specific services for follow-up on discharge Urgent: necessary for client’s health to prevent additional problem from developing; (CCAC)], Receiving agency (nursing home, rehabilitation unit) not necessarily an emergency (24-30h) Elective: is performed when surgical intervention is the preferred treatment for a Preoperative Phase: begins with the decision for surgical intervention and ends with condition that is not imminently life threatening or to improve the client’s life transfer to the OR Required: had to be performed at some point; can be prescheduled Optional: patient’s choice Nurses’ Major Responsibility Patient assessment, Physical problems, Emotional aspects, Understanding surgery/consent, Legal requirements for chart completion, Degree of Risk Read and interpret lab results, Preoperative teaching Major: involves a high degree of risk (extensive reconstruction of or alteration Minor: normally involves little risk (minimal alteration) Nursing Assessment Current health status, Allergies, Medications -list all current Factors Affecting the Risk medications, Previous surgeries, Understanding of the surgical procedure and Age: very young and elder clients are greater surgical risks than children and adult anesthesia, Smoking (Increased risk for pulmonary complications, Teaching on the General Health: surgery is least risky when the client’s general health is good importance of post-op deep-breathing and coughing) Nutritional Status: required for normal tissue repair Alcohol and other-altering substances Medications: regular use of certain medications can increase surgical risk o Cross-tolerance to anesthetic agents; required higher dosage Mental Status: disorder that affect cognitive function o Adverse reactions like withdrawal o Malnourished: delayed wound healing o Needed higher dosage of post-op analgesics Surgical Settings Coping, Social resources, Cultural considerations Medications History: Hazardous to Surgery Antidepressants, phenothiazines, diuretics, steroids, anticoagulants, antibiotics, herbal Nervous System Physical Assessment/ Clinical Manifestations Increased incidence of post-op confusion General Survey: gestures and body movements may reflect decreased energy or Increased incidence of delirium weakness caused by illness Increased sensitivity to anesthetic agents Cardiovascular system: alterations in cardiac status are responsible for as many as Renal System 20-30% of perioperative death Renal blood flow declines with aging Respiratory System: a decline in ventilatory function, assessed through breathing Renal clearance reduced pattern and chest excursion, may indicated a client’s risk for respiratory complications Gastrointestinal Renal System: abnormal renal function can alter fluid and electrolyte balance and Decreased intestinal motility decrease the excretion of preoperative medications and anesthetic agents Decreased liver blood flow Decreased gastric emptying Neurologic System: a client’s LOC will change as a result of general anesthesia but should return to the preoperative LOC after surgery Musculoskeletal Musculoskeletal System: deformities may interfere with intraoperative and Decreased mass, tone, strength postoperative positioning Decreased bone density Gastrointestinal system: alteration in function after surgery may result in decreased or Integumentary absent bowl sound and distention Decreased elasticity Head and Neck: the condition of oral mucous membranes reveals the level of Decreased lean body mass hydration Decreased subcutaneous fat Obesity Immune Status Disabilities Psychosocial Considerations Fear of loss of control (anesthesia) Fear of the unknown (outcome, lack of knowledge) Gerontological Considerations Fear of anesthesia (waking up) Cardiovascular Fear of pain or inadequate post-operative analgesia (pain control) Coronary flow decreases Fear of death (surgery, anesthesia) Heart rate decreases Fear of Separation (support groups) Response to stress decreases Fear of disruption of life patterns (ADLs, work) Peripheral vascular decreases Fear of change in body image and mutilation Cardiac output decreases Fear of dietetic of cancer Cardiac reserve decreases LEVEL OF ANXIETY, COPING ABLITY, SUPPORT SYSTEMS Respiratory System Static lung volume decreases Pulmonary static recoil decreases Sensitivity of the airway receptors decreases Laboratory and Diagnostic Studies Screening tests depend on the condition of the client and the nature of the surgery If test reveals severe problems the surgery may be cancel until the condition is stabilized Informed Consent: Must include adequate disclosure of diagnosis, treatment, risks Routine Screening Test- CBC, blood grouping and x-match, lytes (sodium, and probability of success potassium, chloride, and bicarbonate), fasting blood sugar, BUN & creatinine, ALT, AST, and bilirubin, serum albumin, and total protein, urinalysis, chest x-ray, ECG Patient must demonstrate clear understanding and comprehension (Signed before any preoperative drugs given) Voluntary consent Surgeon responsible for obtaining consent Pre-Operative Teaching: patient has right to know what to expect and how to o Nurse may obtain and witness signature (varies) participate o Verify patient has understanding Increases patient satisfaction Reduces fear, anxiety, stress, pain and vomiting Teaching documented in medical record (ptt. Chart) Explain and demonstrate exercises such as: Permission may be withdrawn at any time Day-of-surgery preparation Final preoperative teaching Deep breathing and coughing Assessment & communication of pertinent findings Diaphragmatic breathing Ensure completion of pre-op prep orders Incentive spirometry Pre-op checklist Leg exercises Turning/moving/alignment Instructions specific to the surgery o Labs, Verify signed consent, History and physical exam, Baseline vital, Consultation records, Nurse’s notes Patient should not wear any cosmetics Pain Management, Coping Strategies, When to stop eating and drinking, Medications o Observation of skin color is important info o Remove nail polish for pulse oximeter Child Life Program Identification and allergy bands Valuables returned to family member or locked up or special equipment postoperatively Dentures, contacts, prostheses are removed Provide patient with information Void before surgery: Prevents involuntary elimination under anesthesia or Inform patients and families if there will be tubes, drains, monitoring devices, o o Fluid/food restrictions (prevents aspiration, N/V) o Need for enema o Need for shower preoperatively/ skin prep Wedding ring taped to finger early postoperative recovery o Done before administration of medication Pre-operative Medications Legal preparation: Check that all forms are completed, correctly signed, and present in chart Purpose: facilitate effective anesthetics, minimize respiratory tract secretions and relax, reduce anxiety o Informed consent, blood transfusion, pre-op survey, pre-op Types: opiates, anticholinergics, barbiturates, prophylactic antibiotics checklist Give as ordered (scheduled time, on call, sent to OR) o Safety considerations Regularly scheduled medications: Verify with the prescriber o Implementation of anesthesia for analgesic, sedative, and muscle relaxant purposes as well as control autonomic nervous system Cardiac meds, asthma, insulin Admission to surgical unit or center (same day surgery) - Review of pre-op teaching: pre-op teaching should have started in pre- Intraoperative Care Team: Surgeon, Anesthesiologist, nurse anesthetist, Scrub nurse, Circulating nurse, OR Techs admission Complete the preoperative assessment Nursing Responsibilities (Before Surgery (in OR) Assess for risk of complications Report abnormal findings Meet the patient in holding area Verify that informed consent obtained ü Psychosocial assessment and support Answers family questions ü Review baseline data and perform baseline assessment including vital signs Develop a plan of care ü Review chart/consents/OR checklist ü Check all pre-op orders... are they complete? ü Pre-op procedures such as IV starts, administer pre-op medications Transportation to OR In-patients transported by cart to surgery from room o Side rails raised and secured Reducing anxiety o Chart and preoperative equipment with patient Ø Psychosocial support for client (if client is awake), Maintaining client dignity, o Family may accompany to holding Maintaining a safe environment, Proper positioning, Injury prevention; sharps, burns Outpatients transported by cart, wheelchair, or may walk o ... Prevention of infection, Prevention of pressure ulcers Method of transport documented by nurse responsible of transfer Family instructed on waiting area where they can be informed on progress Intraoperative Phase: begins with transferring patient to OR-ends with the transfer to the recovery area Experience of Pain PAIN: The International Association for the Study of Pain (1979) …….an unpleasant Purpose of Declaring Pain to be the 5th Vital Sign sensory and emotional experience associated with actual and potential tissue 1. Assuring pain assessment occurs on a regular basis. 2. Efficient use of time when in isolation room. 3. Acknowledging that the pain experience influences the function of HR and Rights of People with Pain Resp. I have the right to have my reports of pain accepted and acted upon by health care Helping nurses make good use of their time while performing 2 professionals. assessments. I have the right to have my pain controlled, no matter what its cause or how severe it 4. damage, or described in terms of such damage. may be. I have the right to be treated with respect at all times. When I need medication for pain. I should not be treated like a drug abuser. Relief from pain is a basic human right – continues to be a major health issue. Pain itself is now considered a separate disease. ……pain is whatever the experiencing person says it is, existing whenever he says it Stimulus for pain – physical, mental or both. does. It is not the responsibility of the clients to prove they are in pain but our …..to accept a client’s report of pain, respect that report and to proceed with responsibility to accept their report of pain. appropriate assessment and treatment. Types of Pain Clients Who Cannot Self-Report: The inability to communicate verbally does not 1. Acute Pain is: Intensified by anxiety & fear, Present for less than 6 months negate the possibility that an individual is experiencing pain and is in need of A source of stress, Occurs abruptly after an injury, procedure or disease, appropriate pain-relieving treatment. Diminishes as healing occurs, Responsive to analgesics Combination of pain evaluation techniques: 2. Chronic Pain: Can be intermittent, vary with intensity or persistent, Known 1. Try of obtain self report cause, a consequence of a disease process, or unknown, There are different 2. Search for potential causes types of chronic pain. 3. Use surrogate reporting Two of the major, non-cancer chronic pains are: 4. Attempt analgesic trial if the presence of pain is suspected – appropriate Musculoskeletal Pain analgesic, re-evaluate behaviors. Neuropathic Pain Nursing Best Practice Guideline: Assessement and Pain Management RNAO Revised 2013: Applies evidence – informed practices of pain prevention and Benefits of Effective Pain Management • Improves quality of life, Decreases hospital stays and clinic visits – takes management with clients in various states of health and illness using pharmacological strain off hospital, pain, Earlier mobilization & healing, participation, and non-pharmacological measures”. satisfaction, stress and anxiety, postoperative complications, Earlier return to work As a nurse, you are ethically responsible for managing pain and relieving suffering. • • Effective pain assessment and management is multidimensional in scope Physiology of Pain and requires coordinated interdisciplinary intervention. Nociceptors: Free nerve endings/receptors capable of responding to painful stimuli You are also legally and ethically obligated to advocate for change in the • Located in various body tissue care plan when pain relief is inadequate. • Activated by thermal, mechanical & chemical stimuli (chemical substances are released) The Concept of Pain Pain is not well understood – you cannot see or feel the client’s pain. Classification of Pain Pain is not simple it is extraordinarily complex. Nociceptive Pain A) Somatic Pain: Bone, joint, muscle, skin, Aching, throbbing, Well localized B) Visceral Pain: Visceral organs, heart, GI tract, Pancreas, Fairly well localized to poorly Effects of Inadewuately Ttreated Pain • Evidence has shown that pain that is not effectively managed can have Neuropathic Pain: abnormal processing of sensory input severe physiological and psychological effects on patients and their families Examples: (RNAO, 2013). • Post herpetic neuralgia • Diabetic neuropathy • Phantom limb pain • However, significant rates of inadequately addressed pain continue to be reported across all patient populations Nursing Responsibilities and accountabilities r/t pain Idiopathic Pain: A complex, multi-faceted state of chronic pain that may have no obvious cause. • Acknowledging and accepting, Preventing pain, Assisting support persons, Reducing misbeliefs about pain, Reducing pain and axiety, Documentation It can involve damaged tissue, injury or malfunctioning nerve fibers or changes in brain processing. • An example of neuropathic pain is phantom limb syndrome. • The brain still receives signals from nerves that originally carried impulses from the now missing limb. • Other types of neuropathic pain include numbness, burning, "pins and needles" sensations and shooting pain. Nociplastic Pain: Altered nociception despite no clear evidence of actual or threatened tissue damage causing the activation of peripheral nociceptors or evidence for disease or lesion of the somatosensory system causing the pain. Sometimes pain persists after a tissue injury has healed and in the absence of nerve injury. Nociceptive Pain: Transduction, transmission, perception, modulation Gate-Control Theory of Pain In addition to physical sensation, pain has emotional and cognitive dimensions and pain impulses can be regulated or blocked by the gating mechanisms located along the CNS Impulses pass through when gate is open and are blocked when gate is closed Closing the gate - basis for pain-relief interventions Sample #1 Sample #2 PQRST Pained P – provoking or precipitating P – place/ location(s) Q – quality of pain A – amount R – radiation of pain I – intensifiers S – severity of the pain N – nullifiers - what makes T – timing the pain better E – effects D –descriptors T – treatment - what medications work for you ? - do you have adverse effects from your medications? Pain Assessment Tools Visual Analog: Place a mark on a line from “no pain” to worst pain” Faces: happy/sad/crying faces Step1 Drugs: • Step 2 Drugs: Mild pain (1-3) Non-opioid ± adjuvant • Moderate Pain (4-6) Weak opioid ± non-opioid ± adjuvant (eg. antidepressants, anti-inflammatories, muscle-relaxants) Caution with meperidine (Demerol) neurotoxicity r/t accumulation of metabolite normeperidine Responses to Pain Injection Kits: distributed by the health unit, they can reverse overdoses cause by Effect on sleep, emotions, concentration, relationships with others Effect on ADL’s, physical activities, appetite May depend on what the pain means to the client……………. certain drug. A life-saving role for users Elderly Considerations Adjuvants/co-analgesics: primary indication other than pain but have been found to St ± All steps may include adjuvants/co-analgesics Affective St have analgesic qualities Aging influences concentrations of water soluble drugs (Morphine) also fat soluble drugs also (Fentanyl) Muscle Relaxants: baclofen Low albumin – s/e and toxic effects Alpha-2-agonists: clonazepam Decline in renal and liver function – greater peak effect and longer duration Tricyclic: amitriptyline Skin changes – topical applications Anticonvulsants: pregabalin, gabapentin Polypharmacy Ability to interpret pain may be complicated by the presence of multiple disease Facial expression and cues are among the most frequently used nonverbal signs to recognize pain in an infant and child. Pharmacologic Pain Management Nonsteroidal anti-inflammatory drugs (NSAIDS) and nonnarcotic analgesics Acetaminophen Pain Assessment Tools: Assessment tools that combine behavioural and physiologic Effective for mild-moderate and chronic pain signs are the most valid for health professionals to use in rating the level of pain in infants and non verbal children. Severe Pain Children Post-surgery or significant injury Opioids (morphine, codeine) • Route – oral, subcutaneous, intramuscular, IV • Oral and IV routes preferred – Why? - Oral route preferred bc IM and SC Assessment of Non Verbal cause increased pain, stress and anxiety in already anxious child • IV preferred bc enables titration of dosage to desired response level • Side Effects – N & V, Constipation, Urinary Retention and Pruritis and… Respiratory Depression – monitor child’s respirations especially when asleep Breakthrough Pain Pain relief should be provided around the clock Delays in analgesics increases the chances of breakthrough pain – pain that emerges as the pain med wears off, resulting in loss of pain control and resulting in the child anticipating and becoming anxious which taxes the child’s ability to rest and recuperate. Types of Breakthrough Pain that Extends Beyond Treated Chronic Pain Incident Pain - predictable and elicited by specific behaviors End-of-dose Failure Pain – occurs towards end of usual dosing Spontaneous Pain – unpredictable and not associated with activity or event Cancer Pain Chronic or acute Comprehensive and aggressive Choice of treatment may change Pharmacological and non-pharmacological together Long-acting/controlled release – MS Contin – 8-12h, 72 hour Fentanyl Patch • IV button pressed prn Possible opioid tolerance – higher dose opioids • delivered only as ordered Chronic pain – give analgesics on a regular basis (ATC) • parameters are ordered Begins with NSAIDS, adjuvants, or both and progresses to strong opioids if • locked syringe chamber pain persists • history Variety of routes Programmed by the health care professional PCA- improved uniform pain control with fewer peaks and valleys in plasma Controlled by the older child concentration, more effective drug action and lower drug dosages After initial pain control achieved with continuous IV, the child presses a button to (5 and over) receive a smaller analgesic dose (bolus dose) for episodic pain relief Opioids Tolerance develops in patients who take opioids for prolonged periods. With tolerance, usage needed for pain relief. Dependence with tolerance, physical symptoms when the opioid is d/c’d. Addiction - need for its psychic effects. Intraspinal: medication infuses directly into the subarachnoid space and cerebrospinal Risk of addiction from therapeutic use of opioids is negligible. fluid • pain relieved through opioid binding to opioid receptors in spinal canal PCA: patient-controlled Analgesia Epidural: medication deposited in the dura of the spinal canal and diffuses into the Self-administer opioids subarachnoid space Cognitive ability Infusion pump Nursing Considerations Pain relief with fewer side effects (including sedation) than with systemic Nurse’s Role R/T discharge teaching discharge medications, pain log, report analgesics significant changes, discuss non-pharmacological approaches, relationship pain and • Potential spinal headache health challenge process, document health teaching • Respiratory depression possible – opioid antagonist available • Possible urinary retention, pruritus, N/V, dizziness, infection at insertion site, Complimentary: Used in addition to conventional treatment recommended by the cardiovascular effects health care provider Others ………………………………………. Alternative: may include the same interventions as complementary but frequently • • become the primary treatment Concomitant Symptoms N.V, anorexia, headache, dizziness, diarrhea, restlessness, difficulty sleeping CNO views complementary therapies as: Adjuncts to care that may be offered in conjunction with, and not to the exclusion of, other approaches Consider how a particular intervention will enhance the overall care for the Distraction: acute and chronic pain, ?with severe pain, draws attention away from the client pain ex. visual, auditory, tactile, intellectual A nurse may propose the use of complementary therapy to a client if she/he has the knowledge to believe that the treatment would benefit the client Training- Specific Therapies Must be done in collaboration with other members of the team and be Biofeedback - instrumentation to mirror psychophysiologic processes that an incorporated into the plan of care individual is not normally aware of but may be able to bring under voluntary control. Cognitive Therapy Behaviour Nursing Accessible Therapies Physio/Occupational Therapy Relaxation: relaxing tense muscles that contribute to pain Therapeutic touch - practitioner uses his/her hands in the client's energy field to bring Guided Imagery: slow, rhythmic breathing with mental image of relaxation and that field to balance and harmony - any physical illness can be viewed as an comfort imbalance in this energy field. Chiropractic - manipulate the body's alignment to relieve pain and improve function Modeling/rehearsal and to help the body heal itself. Acupuncture - thin needles into soft tissue – replace pain with sensations of warmth, Neuropathic Pain and Mirror Therapy tingling or pressure. To use mirror therapy, the affected limb is placed behind a mirror and the reflection of Herbal Therapy - Some herbs may interact with drugs you are receiving for pain or the other limb moving is witnessed. The brain is “tricked” by this optical illusion and other conditions and may harm your health. thinks your affected arm is moving without pain. It is thought that this works by “reorganizing” the brain Others: Natural products, pet therapy, deep breathing, aroma therapy, yoga, exercise, Heat: stimulate nonpain receptors in the same receptor field as the injury stretching-positioning, progressive muscular relaxation, mind body exercises, comfort increases blood flow + dilation, dry and moist heat therapy, rest-sleep Cold/Ice: immediately after injury or surgery, no longer than 20 minutes at a time, applied carefully – assess before, after and during, not applied to areas with impaired Non-Pharmacological Methods for Children (RNAO) circulation or impaired sensation Positive reinforcement Relaxation Preparation/information Memory change DB • Small electrical currents to the skin and underlying tissues Cognitive behavior therapy • Electrodes over painful site, regulated current Hypnosis • Wear with adls Thought stopping and positive self-statements • Rotate electrode sites Distraction • Acute and chronic Vibration: Cutaneous, consider contraindications TENS (Transcutaneous Electrical Nerve Stimulation) Controlling Painful Stimuli in the Client’s Environment • Lift client into bed – don’t pull • Position correctly on bedpan • Tighten and smooth bed linens • Avoid exposing mm to irritants (ex. Stool) • Loosen constricting bandages • Prevent urinary retention • Change wet dressings or linens • Prevent constipation • Check temperature of hot or cold applications • Reduce lighting and ambient sounds Routine Clinical Approach to Pain Assessment and Management: ABCDE A….Ask about the pain regularly. Assess pain systematically B….Believe the client and family in their report of pain and what relieves it C….Choose pain control options appropriate for client, family and setting D….Deliver interventions in a timely, logical and coordinated manner E….Empower clients and their families. Enable them to control their course to the greatest extent possible Deep Vein Thrombosis, Pulmonary Embolism, Hemorrhage Deep Vein Thrombosis Venous Thrombi (plural) • RBC, WBC, Platelets, Fibrin along with tail like appendage • Tail grow or propagate in the direction of blood • Blood clot in a deep vein & artery • Likes valves of veins where venous stasis • Most serious complication - clot could dislodge and travel to the lungs • size to occlude lumen • Medical emergency • Range in size from 1 mm in diameter to a mass that can completely obstruct • the vein Exact Cause of VTE Unknown Incidence increases with age, rare in children Contributing Factors: Vircho’s Triad Stasis of the blood/alterations in blood flow Bedrest, bedridden, immobilization, Obesity, History of varicosities Deep Vein Thin walled (less muscle) (various veins, twisted large veins), Heart failure/shock, Veins dilated with • Run parallel to arteries certain meds • Unidirectional flow back to the heart SCI, Age, Surgery past 3 months, Surgery – anesthesia, Cast, Driving/flying Endothelial injury/vessel wall injury fracturess + dislocations, Diseases of veins, Trauma, Chemical irritation, Central venous catheters, Repetitive motion injury • Check toes with TEDS Altered blood coagulability Blood dyscrasia, OCP, HRT, Polycythemias, Deficient blood volume, Nursing Considerations Stress response • Assess condition of skin – look for any lesions, gangrenous condition, recent vein ligation – may compromise circulation Predisposing Factors: Pregnancy, Cancer, Smoking, Height, Family history, Certain • Remove q8h – assess calves for redness, warmth and tenderness inflammatory diseases, History of DVT + PE • Also sensation, movement, edema and palpation of distal pulses Calf Circumference: unilateral in calf circumference can be an early indication Upper Extremity Venous Thrombosis • Not as common as lower • Reasons: IV catheters, Disease states, Trauma, Dialysis catheters, Central • Daily, Mark a point on each calf 10 cm from mid patella (> 3cm difference in circumference btw calves) • Thigh – measure those who are prone lines, Effort thrombosis Prophylaxis: Doctors Order (prevention) Prevention Anticoagulation Body positioning + position change • Unfractionated Heparin (UFH) – 5,000u bid to tid • Low Molecular Weight Heparin (LMWH) – daltiparin, enoxaparin • Vitamin K Antagonist – warfarin • Prophylactically can decrease risk of DVT up to 50% • Prevent pressure on posterior knee + deep veins in lower extremities. Don’t: • Cross legs, Sit for long periods – hip flexion compresses large veins of the legs, Wear clothing that constricts legs or waist, Put pillow under knee, Mechanical Massage legs • Graduated compression stockings • Intermittent pneumatic compression device Exercise – activity causes contraction of skeletal muscles – puts pressure on veins to Prevent blood clots in lower extremities, Decrease venous stasis by promote venous return – decreases stasis increasing venous return through deep veins of legs, Connects to pump to • ROM – prevent thrombi inflate and deflate – cycle • Ankle pumps • Foot circles • Knee flexion Elastic Stockings- TED- Thromboembolic Device Hose or thigh high anti-embolic stocking antiembolic exercises q1h w/a Maintain external pressure on muscles of lower extremities – promote Others: Life style changes – weight, smoking, activity, Monitor urinary output, Maintain venous return BP • Accurate size Clinical Manifestations- Superficial Veins: Pain/tenderness, Redness, Warmth, Most • Ensure stockings are insitu dissolve spontaneously • Clean and dry • Treatment: BR, Elevation, Analgesics, Anti-inflammatory • Can meet this objective but cannot dissolve a thrombus that has already formed. No symptoms to nonspecific Thromboembolytic Therapy Tenderness affected limb Surgical Treatment: Thrombectomy, IVC filter, Ligation, clips Pain Edema/Swelling Discoloration or redness • Prevent extension or development of new thrombi Increased skin temp • Intermittent or continuous IV infusion for 5 days Superficial veins prominent • Heparin effective when aPTT is 1.5 times the control Anticoagulation Agents: (aPTT = activated partial prothrombin time) Suspected DVT: Reported Immediately • Monitored + regulated by aPTT, INR + platelet count • Nurse can elevate leg but avoid pressure on suspected thrombus area • Oral anticoagulants administered with heparin • No one massages area • Used with renal insufficiency b/c not cleared by kidneys • Homan’s Sign on calf pain on dorsiflexion - * contraindicated when DVT • Increased chance of hemorrhagic complications suspected as vigorous dorsiflexion may dislodge thrombus Diagnostics Ultra Sounds: Series of u/s are done over several days Antidote for Heparin 1. Protamine sulphate Blood Tests: Almost all who develop severe DVT have an elevated blood level of a Considerations r/t antidote? clot dissolving substance called D Dimer Dosage r/t amount of heparin in body and 1mg neutralizes 100u of heparin Venography: Dye injected into a large vein in foot/ankle. Used less frequently b/c less invasive methods can usually confirm diagnosis MRI/CT: Visual images can show a clot • Used for some dvts - also prevents extension or new thrombi • Longer half-life of unfractionated (OD or BID) • Fewer bleeding complications than unfractionated Stop the clot from getting any bigger and preventing the clot from breaking • Ex. Enoxaparin, daltiparin loose and causing a __________. • Dosage adjusted by weight Goal of DVT Management 1. Anticoagulation Agents: Low-Molecular-Weight Heparin (LMWH) 2. Reducing chance of deep vein thrombosis again. 3. Prevent Post Thrombotic Syndrome Treatment Options Highest Risk but advantages………… • Fondaparinux - selective inhibitor of activated factor X Anticoagulation Agents: Oral Anticoagulants Pharmacological Therapy: • Warfarin – vitamin K antagonist Anticoagulant Therapy: Preventing or reducing blood clotting within the vascular • Routine coagulation monitoring for therapeutic response over time system. • Narrow therapeutic window + slow onset of action – heparin with warfarin • Other meds + intake of foods containing vitamin k What is the antidote for warfarin (Coumadin)? 1. • Usually on for 3 months or longer • Must take Warfarin at same time each day + brand • Contraindicated in pregnancy (LMWH or SQ Heparin) Vitamin K Considerations r/t antidote? More difficult to reverse if no active bleeding – may hold dose INR=International .9 -1.1 Normalized Ratio Atnicoagulation Agents: • Lysis and dissolve thrombus • Ex. T-PA, Activase, Urokinase, Streptokinase • Given within first 3 days • 3X higher incidence of bleeding than heparin • Less long term damage to valves, reduced chronic venous insufficiency and post thrombotic syndrome Surgical Management When: aPTT= activated partial 28-38 seconds prothrombin time PT=prothrombin time 10-14 seconds Platelets 150-400 x 10 9th/L Hemoglobin (HGB) Male 135-170 g/L Female 115-160 g/L Hematocrit (HCT) . Danger of PE Male .4-.51 Female .34-.48 2. Permanent damage to extremity will probably result 3. Anticoagulants or thrombolytic therapy contraindicated Such as [many reasons]: bleeding, severe trauma, severe liver or renal disease, CVA, L+D + + + + Options: Thrombectomy, Vena cava filter, Filter traps Anticoagulation • IV pump - unfractionated • Clotting profile, with ongoing coagulation testing • Heparin effective (therapeutic – aPTT is 1.5 times the control) • Oral anticoagulants ex.warfarin (coumadin) monitored by PT or INR – effect is delayed for 3-5 days - usually administered with heparin until desired anticoagulation achieved (PT is 1.5 to 2 times normal or INR is 2 to 3) when reaches this for 2 consecutive days d/c heparin • Warfarin – narrow therapeutic window Anticoagulation Therapy Monitoring Bleeding: Often first sign – bleeding from kidney, Bruises, nosebleeds and bleeding gums, Cuts that continue to bleed, Surgical incisions What else do we need to consider?? Checking blood levels before administering, Reddish/brown urine, Melena, Severe headaches, Abdo pain, Hemoptysis Thrombocytopenia - Decrease in platelets - 150-400 x 109/L • Heparin induced thrombocytopenia[HIT] • Beginning warfarin with heparin can provide stable INR • Less with LMWH • Regular monitoring of counts • If does occur – platelet aggregation studies, heparin d/c’ed, and protamine sulfate given Numerous Drug Interactions: • Vitamins • Cold medicine Chronic venous insufficiency • Antibiotics Phlegmasia cerulea dolens • ASA • Mineral Oil • Anti-inflammatory agents [ibuprophen] • Herbal/nutritional supplements Teaching Complications of DVT- PE Pulmonary Embolism (PE) • Collection of particulate matter (solids, liquid, gaseous) enters systemic venous circulation and lodges in pulmonary vessels. • Obstructs pulmonary circulation causing impaired gas exchange, constriction Self injections – site and technique of regional blood vessels and bronchioles thus decreasing oxygenation. Can - Avoid injury be fatal. - Signs and symptoms to report • - Medications interactions - Diet Can be caused by blood clot (most common), foreign body, tumor, fat emboli, amniotic fluid, pus. PE is not a disease but a complication of underlying venous disease/complications - Routine monitoring required - Communicate anti-coagulation to all other HCP - Same brand and same time • Deep veins of the legs - Wear ID • Most lethal from femoral or iliac veins - Avoid ETOH • Right side of heart and upper extremities - Check with HCP before stopping • Pelvic veins - If pregnant or suspect pregnancy - Soft tooth brush, electric razor - Avoid marked changes in eating • Immobilization/paralyzed - Hydration • Surgery Pathway PE RISK FACTORS • Trauma Client Comfort and Healing • Increased blood coagulation Adjuncts to Therapy: • History of varicose vein(s), • Activity depends……. • Obesity, smoking, pregnancy, OCP, CHF, stroke • Elevation • History • Warm moist packs • Age • Analgesics • Septic • Walking preferred over sitting/standing • Cancer + therapy • Bed exercises • Hydration Considerations- PE • Completely/partially obstructs a pulmonary artery/branches + alveolar dead • Peripheral vascular studies space • ABG’s • Continues to be ventilated but received little or no blood flow • Gas exchange impaired or absent in this area Interventions • Substances are released from the clot = regional blood vessels and Goals bronchioles constrict increase alveolar gas exchange • ed pulmonary vascular resistance improve tissue perfusion • ed pulmonary vascular resistance and decreased size of pulmonary get rid of embolism vascular bed prevent complications • Causes in pulmonary arterial pressure and in rt ventricular work • When workload needed to the rt ventricle exceeds its capacity rt ventricular Priority Nursing Actions: HOB, Oxygen, VS, O2 sat, Breath sounds, Call, IV, Testing, failure occurs = in cardiac output followed by in systemic bp and Monitoring, Catheter, Medications, Emotional support, Anticipate possible treatment development of cardiogenic shock! Anticoagulation Prevention • Prevent DVT Major Elective Surgery Heparin and Warfarin – traditional – heparin generally recommended for pt diagnosed with PE • Usually one time Iv bolus [5,000u] then continuous infusion – pump – • Low dose of Heparin SQ 2h preop + continued q8-12h until discharged maintain PTT at 1.5 – 2.0 times the normal level • Enhances activity of antithrombin 111, a major plasma inhibitor of clotting • Many issues with heparin factor X • Heparin continued with Warfarin until INR within therapeutic range of 2.0 – Active thrombotic process or undergoing major ortho, prostatectomy, eye or brain surgery • 2.5 • LMWH (low molecular weight heparin) LMWH (high dose) or heparinoids can be used to maintain therapeutic PTT while Warfarin adjusted Signs and Symptoms (PE) Dyspnea*, Tachypnea*, Tachycardia, Chest pain/chest • Warfarin for 3-6 months post (INR 2-3) wall tenderness*, Syncope, Diaphoresis, Anxiety/apprehension • Lepirudin and agrathroban – are alternatives if heparin or heparinoids are Cough/hemoptysis, Hemoptysis Diagnostic Tests and Assessment contraindicated Thrombolytics • D dimer Thrombolytic Therapy • Ventilation-perfusion scan -Severely compromised – only for PE affecting significant area to lung and causing • Pulmonary angiography hemodynamic instability - resolves quicker • Spiral CT -Bleeding significant s/e • CXR -Contraindications • ECG • CVA post 2 months + ICP • Active bleeding Common causes: • Surgery • Tissues that cannot be entirely prevented from bleeding • Recent L+D • Blood clotting to stop hemorrhage • Trauma • Clips or ties around vessels become loose • Severe hypertension Blood work checked first, heparin stopped, no invasive procedures – after, started on Classification of Hemorrhage anticoagulants Type of Vessel Capillary, Venous, Arterial Visibility Evident, Concealed, Other considerations Surgery: embolectomy, clips, filter Preventing Thrombus: • Assessing potential for PE • Monitoring Thrombolytic Therapy • Managing Pain • Maintaining Oxygenation • Anxiety • Complications – cardiogenic shock, right ventricular failure Grade 4 – Debilitati ng Blood Loss – associate d with Fatality Grade 1 – Petechial Bleeding WHO Gradin g to Measur e Bleedin g Grade 3 – Gross Blood Loss Grade 2– Mild Blood Loss Hemorrhage Post-Operative Management Hemo = blood orrhage = burst forward Loss of large amount of blood externally or internally in a short period of time Signs and Symptoms • Internal or external • Acute or chronic • May affect different vessels and have varying results conjunctive], HR increases + becomes weak, temp decreases, RR rapid and • Into closed cavity may cause organ damage deep, Delayed cap refill, Spots/eyes, Decrease urinary output, Tinnitus, • Presentation varies by anatomical location Mental status changes • Apprehensive, Restless, Thirsty, Skin – cool, moist, pale [+lips + Serious complication Nursing Interventions: team approach, control bleed, adequate circulating blood Any point in the immediate post-op period or up to several days after surgery volume, prevent shock, assess cause! Time frame: External • primary – time of surgery • Rapid assessment • intermediary – during first few hours after surgery • Place dressing with direct firm pressure • Secondary – sometime after surgery • Elevate and immobilize if bleeding from extremity • Not restricted to the surgical wound • Tourniquet – last resort Internal • Blood, Surgery, Supine + raise leg, Warmth, Monitor oxygenation • ABG’s • Consider – patient safety and special considerations r/t blood loss replacement