PABNA UNIVERSITY OF SCIENCE AND TECHNOLOGY Department of Pharmacy Assignment on VITAMINS Course Title: Medicinal Chemistry-I Course Code: BPH 2203 Submitted to, Submitted by, G. M. Masud Parvez Lecturer Department of pharmacy Naila Hossain Roll no: 181301 Reg no: 1135167 Session: 2017-18 2nd Year 2nd Semester Department of pharmacy Pabna University of Science and Technology Pabna University of Science and Technology CONTENT Topic page 1) Definition 3 2) Classification 3 3) Information of vitamins 3 4) Conclusion 6 VITAMINS Definition: Vitamins are complex organic compounds that are needed in small amounts by the body for normal growth and metabolism. They include vitamins A, C, and K etc. Classification: On the basis of their solubility vitamins are mainly 2 types. 1)Fat- Soluble Vitamins: Vitamins that dissolve in fat. Because fat is easily stored on our body, fat-soluble vitamins can be stored within our fat. The fat- soluble vitamins are A, D, E and K. 2)Water Soluble Vitamins: Vitamins that dissolve in water. Because our body is a watery environment, these vitamins can move through our body pretty easily, and they can also be flushed out by the kidneys. Water soluble vitamins include the B-complex vitamins and vitamin C. Information of Vitamins: Vitamins A (Retinol) Sources Yellow or orange fruits and vegetables, green leafy vegetables, dairy products, liver, tuna, sweet potato Medicinal Uses Used in acne, measles, in the treatment of acute diarrhea and cutaneous diseases, reproduction, Lowered resistance to infections, Darkadaptation, bone and tooth growth, vitamin A deficiency, prevent some cancers Deficiency diseases Night blindness, Hyperkeratosis, Keratomalacia and Xerophthalmia B1 (Thiamine) B2 (Riboflavin) B3 (Niacin) B5 (Pantothenic acid) Fortified cereals, oatmeal, meats, rice and pasta, whole grains, liver, eggs, pasta Used in Beriberi, Nervous inflammations, neuralgias, Cardiac dysfunction caused by alcoholism, growth and muscle tone Dairy milk, yogurt, cheese, eggs, salmon, beef liver, chicken breast Used in Sore tongue, Ariboflavinosis, sores in the mouth, Cheilosis, itching and peeling skin Corneal opacity on the nose and scrotum, ariboflavinosis, Photophobia and blurred vision, Corneal vascularization and eye itching Poultry, fish, meat, whole grains, fortified cereals, avocados, green Peas, sweet Potatoes Helps to treat Type 1 Diabetes, helps lowering cholesterol, ease arthritis and boost brain function, Pellagra, Multiple B complex deficiency syndrome Mushrooms, nuts, beans, peas, lentils, meats, dairy products Used in acne, alcoholism, allergies, asthma, baldness, conjunctivitis, depression, insomnia, leg cramps, yeast infections, obesity Beriberi, Wernicke Korsakoff syndrome Pellagra Paresthesia, Anemia, Insomnia B6 (Pyridoxine) B7 (Biotin) B9 (Folic acid) B12 (Cyanocobalamin) Soya beans, wheatgerm, oats, bananas, peanuts, meat, dairy products Prevent Clogged arteries and cancer, used in premenstrual syndrome, age related macular degeneration (AMD), Reduce Alzheimer’s Risk, Used in peripheral neuritis, hypochromic anemia, irritability and convulsion Walnuts, peanuts, cereals, milk, egg yolks, salmon, banana, avocado Used in the treatment of Dermatitis, Enteritis dryness of the eyes, appetite loss, hair loss, brittle hair, burning or prickling sensation in the hands and feet, fatigue, depression Spinach, broccoli, beans, fresh fruits, sunflower seeds, whole grains, eggs, seafood Fish, meat, poultry, eggs, milk, fortified cereals Anemia, peripheral neuropathy, Dermatitis, Stomatitis, Glossitis Used in the treatment of Anemia megaloblastic anemia, hemolytic anemia, achlorhydria or hypochlorhydria, alcoholism Used in osteoporosis, macular degeneration, depression, memory loss, angular stomatitis, juvenile pernicious anemia, celiac disease, inflammatory lesions Megaloblastic anemia, Pernicious anemia C (Ascorbic acid) D (Calciferol) E (Tocopherols) K (Phylloquinone) Citrus fruits, peppers, strawberries, broccoli, mango, lemon Used in the treatment of Scurvy, swelling scurvy, poor wound of gums healing, iron deficiency, high blood pressure, dementia and heart disease Cod liver oil, fortified milk, sunlight, salmon, sardine, egg yolk, red meat Used in the treatment of Rickets, Osteoporosis, Vitamin D deficiency and osteomalacia, improves tooth consistency, helps to maintain heart action and nervous system Rickets, Osteomalacia, Osteoporosis, Colorectal cancer In cardiac, vascular and muscular disorders, fat with high levels of unsaturated fatty acids absorption disorders, prevent coronary heart disease, cancer and inflammation Mild hemolytic anemia in newborn infants, sterility Disorders of blood coagulation Bleeding diathesis Vegetable oils, nuts, seeds, spinach, broccoli, egg yolks, avocado Cereal grains, vegetable oils, broccoli, spinach Conclusion: Vitamins perform hundreds of roles in the body. They are found in different kinds of fruits, vegetables, fish and dairy products etc. So, we have to eat a healthy diet to maintain a life, free from all those diseases.