ACTIVE LEARNING TEMPLATE: Medication Zarkpa Wreh STUDENT NAME______________________________________ Aspirin MEDICATION___________________________________________________________________________ REVIEW MODULE CHAPTER____________ (Anti-inflammatory, antiplatelet, antipyretic) CATEGORY CLASS__NSAID _____________________________________________________________________ PURPOSE OF MEDICATION Expected Pharmacological Action -Blocks the activity of cyclooxygenase, the enzyme needed for prostaglandin in synthesis. - Aspirin inhibits platelets aggregation by interfering with productionof thromboxan, A2 a substance that stimulates platelet aggregation. (2020 Nurses Drug Handbook, 2020) Therapeutic Use -Inhibition of platelets aggregation, which protects aganist ischemic stroke and myocardial infarction. _Inflammation suppresion (ATI, RN Pharmacology for nursing, Edition 8) Patient is prescribed Aspirin as a prophalyxis for her chest pain Complications Medication Administration -Headaches, dizziness, sweating, Tinnitus, respiratory alkalosis, GI bleed,heptotoxicity, decrease blood iron level, prolonged bleeding time, Confusion (2020 Nurses Drug Handbook, 2020) Contraindications/Precautions -Active bleeding or coagulation disorders; breastfeeding; current GI bleed or ulcers; hypersensitivity to aspirin, aspirin products, other NSAIDs, tartazine dye, or their components, third trimester of pregnancy. (2020 Nurses Drug Handbook, 2020) Interactions -ACE inhibitors, beta blockers-decreased antihypertensive effect. -Possibly acetazolamide toxicity -Activated charcoal decreased aspirin absorption (2020 Nurses Drug Handbook, 2020) Evaluation of Medication Effectiveness -Reduction in inflammation -Reduction of fever -Relief from mild to moderate pain (ATI,RN Pharmacology for Nursing, Edition 8) Evaluation of medication in the patient was evidence by the reduction of the patient's chest pain. ACTIVE LEARNING TEMPLATES May be administer PO, Suppositories. Adults: 325 to 650 mg every 4hrs. or 500 mg every 3 hr as needed to relieve mild pain or fever. 160-325 mg daily for 30 days to prevent acute myocardial infarction. (2020 Nurses Drug Handbook,2020) Patient's dose: Aspirin 81 mg daily Nursing Interventions -Don't crush timed-release or controlled release aspirin tablets unless directed. - Ask about tinnitus. This reaction usually occurs when blood aspirin level reaches or exceeds maximum dosage for therapeutic effect. (2020 Nurses Drug Handbook, 2020) Client Education -Stop aspirin 1 week before an elective surgery or expected childbirth. -Take NSAID with food , milk, oe an 8 oz glass of water to reduce gastric discomfort. (ATI, RN Pharmacology for Nursing, Edition 8) (2020 Nurse's Drug Handbook, 2020) (ATI, RN Pharmacology for Nursing, Edition 8)