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STATUTORY WARNING
• THE OBJECTIVE OF THIS WORKSHOP IS NOT TO PROMOTE THE USE OF PERFORMANCE ENHANCEMENT DRUGS
• THE CONTENTS OF THIS WORKSHOP HAVE NOT BEEN TESTED OR STUDIED ON HUMAN TRIALS (COOKING ON
YOUTUBE)
• ANABOLIC STEROID USE IS NOT AS LETHAL AS MANY INDIVIDUALS CLAIM
• ANABOLIC STEROID USE IS NOT AS SAFE AS MANY INDIVIDUALS CLAIM
By Pankaj Narsian
LECTURE 1 LAYOUT
• STEROID FUNDAMENTALS
• CLINICAL & PROFESSIONAL USES
• STEROID RECEPTOR MECHANISM
• 4 LAWS OF EFFECTS
• THE DARK HORSE
• GUIDELINES TO PLANNING A CYCLE
• OVERVIEW ON AAS
• ADVERSE EFFECTS (PHYSICAL/PSYCHOLOGICAL)
By Pankaj Narsian
STEROID FUNDAMENTALS
By Pankaj Narsian
WHAT IS A STEROID
THE TERM “STEROID” REFERS TO A BROAD
CLASS OF ORGANIC COMPOUNDS SUCH AS
CARBON AND HYDROGEN
By Pankaj Narsian
WHAT IS A STEROID
MADE UP OF HORMONES AND VITAMINS WITH
A STRUCTURE CONTAINING FOUR CARBON
RINGS
By Pankaj Narsian
THREE MAIN GROUPS IN STEROIDS
GONALDAL
COMPOUNDS
• SYNTHESISED IN
GONADS
GLUCOCORTICOIDS
• SYNTHESISED IN
ADRENAL CORTEX
• CORTISOL
• CORTISONE
MINERALCORTICOIDS
• SYNTHESISED IN
ADRENAL CORTEX
• ALDOSTERONE
By Pankaj Narsian
STEROIDS DIVIDED BY FUNCTION
ANDROGENS
ESTROGENS
PROGESTOGENS
ANABOLICS
CATABOLICS
By Pankaj Narsian
DIFFERENT TYPE OF STEROIDS
Cholesterol
Cholecalciferol
(Vitamin D)
Estrogen
Testosterone
Cortisol
By Pankaj Narsian
STEROID RECEPTOR COMPLEX
By Pankaj Narsian
STEROID RECEPTOR COMPLEX
•
STEROIDS ARE FAT-SOLUBLE
•
EASILY DIFFUSES ACROSS THE CELL MEMBRANE INTO THE
CYTOPLASM
•
IN THE CYTOPLASM, THE STEROIDS BIND TO RECEPTORS,
WHICH ARE COMPOSED OF PROTEINS
•
THIS FORMS WHAT IS KNOWN AS A STEROID-RECEPTOR
COMPLEX
By Pankaj Narsian
STEROID RECEPTOR COMPLEX
By Pankaj Narsian
STEROID RECEPTOR COMPLEX
• THE COMPLEXES THEN UNDERGO DIMERIZATION,
• WHERE TWO COMPLEXES BIND TOGETHER TO FORM A DIMER.
• THE DIMER WILL THEN TRAVEL TO THE NUCLEUS OF THE CELL AND BIND TO DNA, WHERE IT PROMOTES
GENE TRANSCRIPTION AND TRANSLATION, LEADING TO THE PRODUCTION OF PROTEINS (PROTEIN
SYNTHESIS)
By Pankaj Narsian
THE DARK HORSE
CHOLESTEROL
By Pankaj Narsian
CHOLESTEROL
• CHOLESTEROL IS THE PRECURSOR TO TESTOSTERONE
• THE BASE STEROIDAL COMPOUND THAT THE BODY’S CELLS USE TO SYNTHESIZE ALL OTHER STEROIDS
• ESTROGEN, TESTOSTERONE AND VITAMIN D ARE SYNTHESIZED WITH HELP OF CHOLESTROL
By Pankaj Narsian
CHOLESTEROL
By Pankaj Narsian
WHAT IS TESTOSTERONE
• MALE SEX HORMONE
• SUPPORTS HEALTHY LIBIDO LEVELS (AKA SEX DRIVE)
• DEVELOPMENT OF MALE SECONDARY SEX CHARACTERISTICS (FACIAL AND BODY HAIR, DEEPER VOICE)
• THE DEVELOPMENT OF LEAN MUSCLE MASS (THE MOST RELEVANT TO A BODYBUILDER)
By Pankaj Narsian
OVERVIEW ON AAS
By Pankaj Narsian
AAS AND LAW
• CLASS C DRUGS TO BE SOLD ONLY BY PHARMACISTS WITH A DOCTOR'S PRESCRIPTION
• POSSESSION OR IMPORTING WITH INTENT TO SUPPLY (WHICH INCLUDES GIVING THEM TO FRIENDS) IS
ILLEGAL AND COULD LEAD TO PRISON AND AN UNLIMITED FINE
• MANY SPORTING ORGANIZATIONS SUCH AS WADA HAVE BANNED THE USE OF CERTAIN STEROIDS
By Pankaj Narsian
WHAT ARE AAS STEROIDS
•
SYNTHETIC VARIATIONS OR DERIVATIVES OF THE MALE SEX HORMONE TESTOSTERONE
•
THE RIGHT TERM IS ANABOLIC-ANDROGENIC STEROIDS & NOT JUST ANABOLIC STEROIDS
•
ANABOLIC REFERS TO MUSCLE BUILDING AND ANDROGENIC REFERS TO INCREASED MALE SEX CHARACTERISTICS
•
WHILE ALL STEROIDS HAVE THE SAME FOUR RING CARBON STRUCTURE, SIMPLE CHEMICAL ALTERATIONS PRODUCED
DIFFERENT EFFECTS IN TERMS OF ANABOLIC/ANDROGENIC ACTIVITY
By Pankaj Narsian
THE RISE OF AAS
•
IN THE 1930S, SCIENTISTS FOUND THAT AAS COULD INCREASE THE GROWTH OF MUSCLE IN LAB ANIMALS. SO THE
COMPOUNDS WERE THEN USED TO TREAT DEBILITATING DISEASES IN HUMANS.
•
IN THE 1950S, A DOCTOR, JOHN ZIEGLER HAD DISPENSED AN ORAL ANABOLIC STEROID BY THE NAME OF DIANABOL.
•
SOON AFTER, ATHLETES BEGAN TO USE THIS STEROID IN ORDER TO INCREASE MUSCLE MASS AND STRENGTH.
•
SOON, MORE AND MORE ANALOGS AND DERIVATIVES WERE BEING MADE AVAILABLE TO ATHLETES.
By Pankaj Narsian
DERIVATIVES & ANALOGUES
TESTOSTERONE W/
WATER & OIL
TESTOSTERONE
NANDROLONES/
PROGESTINS
DHT
TREN/DECA/
ANADROL
ANAVAR/
WINSTROL/
MASTERONE/PRIMO
By Pankaj Narsian
ANABOLICS AND ANDROGENIC ACTIVIY
ANDROGENIC ACTIVITY
• REFERS TO HOW POTENT THE DRUG IS AT
INDUCING THE DEVELOPMENT OF MALE SEXUAL
CHARACTERISTICS
ANABOLIC ACTIVITY
• REFERS TO THE STEROID'S ABILITY TO
FACILITATE SKELETAL MUSCLE GROWTH
By Pankaj Narsian
4 LAWS OF EFFECTS
By Pankaj Narsian
Genetics
Age
Compound
4 LAWS OF EFFECTS
Dose &
Duration
By Pankaj Narsian
GENETICS
EVERY INDIVIDUAL IS DIFFERENT, GOVERNED BY A
BLUEPRINT WHICH IS GENETICS OR DNA
DIFFERENT RESPONSES TO ANY CHEMICAL,
COMPOUND, ANABOLIC STEROID, FOOD OR DRUG IN
EXISTENCE
ONE EXPERIENCES A SIDE EFFECT BUT THE OTHER
DOESN’T
By Pankaj Narsian
AGE
GENETIC RESPONSE CHANGES OVER TIME
AGE IS A FACTOR, WHETHER OR NOT AN
INDIVIDUAL WILL EXPERIENCE A SIDE EFFECT
AND HOW SEVERE IT WILL BE
By Pankaj Narsian
COMPOUND
TODAY HUNDREDS OF DIFFERENT ANABOLIC
STEROID COMPOUNDS EXIST
THEREFORE DIFFERENT SIDE EFFECTS CAN
RESULT WITH VARYING INTENSITIES.
By Pankaj Narsian
high doses
DOSE
HIGH DOSES MOST USUALLY RESULT IN
INCREASED INCIDENCES AND SEVERITY OF
SIDE EFFECTS
By Pankaj Narsian
DURATION
DURATION IS ALSO A VERY INFLUENTIAL
FACTOR.
THE LONGER A PARTICULAR ANABOLIC
STEROID IS UTILIZED, HIGHER WILL BE THE
CHANCES OF SIDE EFFECTS
By Pankaj Narsian
GUIDELINES
By Pankaj Narsian
GUIDELINES TO PLANNING A CYCLE
NATURAL
SYNTHETIC
By Pankaj Narsian
NATURAL GUIDELINES
HOW TO BOOST TESTOSTERONE
By Pankaj Narsian
NATURAL GUIDELINES
•
1 – TESTOSTERONE BOOSTERS AND KEEP A BODY FAT LEVEL BELOW 20%
•
2 – STRENGTH TRAINING AND HIGH INTENSITY INTERVAL TRAINING
•
3 – ZINC AND VITAMIN D
•
4 – FATS FROM FOODS SUCH AS NUTS, OILS, EGGS, MEATS AND AVOCADOS
•
5 – PROTEIN WITH A HIGH LEUCINE CONTENT FROM MEATS, NUTS, DAIRY PRODUCTS, AND WHEY PROTEIN
By Pankaj Narsian
GUIDELINES FOR SYNTHETIC USE
HOW TO BOOST TESTOSTERONE
By Pankaj Narsian
GUIDELINES TO SYNTHETIC USE
Rule 1 – Minimum age
Rule 2 – Testosterone as a base
Rule 3 – Short Cycle lengths
Rule 4 – Start lowest effective dose
Rule 5 – Stacking of compounds
Rule 6 – Body fat
By Pankaj Narsian
RULE 1 –
MINIMUM AGE
EVERY INDIVIDUAL’S GENETIC ‘PROGRAMMING’ IS DIFFERENT
MATURATTION AGE IS DIFFERENT FOR EVERYONE, SOME INDIVIDUALS
ATTAIN MATURATION AT APPROXIMATELY 24 YEARS OF AGE, AND OTHERS
WILL PERHAPS MATURE AT AN EVEN OLDER AGE
TESTOSTERONE LEVELS IN MALES ARE CONTINUALLY RISING UNTIL THE
MEDIAN AVERAGE AGE OF APPROXIMATELY 24 – 25 YEARS OLD, AT WHICH
POINT THESE LEVELS REACH THEIR PEAK AND BEGIN TO DECLINE
By Pankaj Narsian
RULE 1 –
MINIMUM AGE
HPTA CONTROLS ENDOGENOUS T PRODUCTION
NO SPECIFIC ‘TEST’ TO DETERMINE FULL MATURATION
OF THE SYSTEMS
PRIOR TO THE AGE OF 24, THE RISKS OF PERMANENTLY
DISRUPTING THE ENDOCRINE SYSTEM IS EXTREMELY
HIGH
By Pankaj Narsian
RULE 2 –
TEST AS BASE
T IS LITERALLY THE ORIGINAL ANABOLIC STEROID
IT IS THE HORMONE THAT EACH INDIVIDUAL’S BODY
ALREADY PRODUCES, USES, AND IS ACCUSTOMED TO
THEREFORE, THE USE OF AAS IS SIMPLY THE
EQUIVALENT OF INTRODUCING MORE OF A HORMONE
INTO THE HUMAN BODY THAT IT ALREADY
MANUFACTURES AND USES
By Pankaj Narsian
RULE 3 – SHORT
CYCLE LENGTHS
LESS IS MORE
HIGHER DEGREES OF HPTA SUPPRESSION
LEYDIG CELLS ATROPHY & DE-SENSITISATION
SHORT-ESTER 8 TO 10 WEEKS
LONG-ESTER 10 – 12 WEEKS
By Pankaj Narsian
RULE 4 – LED
• LOWEST POSSIBLE DOSE, GROW AND INCREASE AS REQUIRED
• USERS UNDERESTIMATE THESE HORMONES BUT CULPRIT IS USUALLY A FLAW IN NUTRITION OR TRAINING
• HUMAN BODY ONLY MANUFACTURES APPROXIMATELY 50 – 70MG WEEKLY OF TESTOSTERONE
• 500MG IS APPROXIMATELY 7 – 10 TIMES THE AMOUNT THAT THE HUMAN BODY PRODUCES. THEREFORE,
300MG WEEKLY SHOULD THEN BE PERFECT FOR ANY FIRST-TIME BEGINNER CYCLE
By Pankaj Narsian
RULE 5 – NO. OF COMPOUNDS
• 2 OR MORE, COMPLETELY UNNECESSARY
• FOR THE AVERAGE CASUAL RECREATIONAL ANABOLIC STEROID USER
• 3 OR MORE, MAY BE NECESSARY
• FOR COMPETITIVE BODYBUILDERS AND PROFESSIONAL ATHLETES
By Pankaj Narsian
TYPES OF USE
By Pankaj Narsian
CLINICAL USE
• HORMONAL ISSUES
• CANCER
• DELAYED PUBERTY
• AIDS
• BURN VICTIMS
• ACCIDENT CASES
By Pankaj Narsian
PROFESSIONAL USE
• ENDURANCE
• TRAIN HARDER AND LONGER
• PERFORMANCE
• FASTER RECOVERY TIME
• STIMULATE MUSCLE GROWTH
• CHANGES IN APPEARANCE
By Pankaj Narsian
ADVERSE EFFECTS OF AAS
By Pankaj Narsian
CARDIOVASCULAR
• CHOLESTEROL
• HEART ENLARGEMENT
• BLOOD PRESSURE
By Pankaj Narsian
HEPATOTOXICITY
• HEPATOTOXICITY IS DUE TO USE OF ORAL ANABOLIC STEROIDS
• CHEMICAL MODIFICATIONS ALLOW ORAL BIOAVAILABILITY (ON THE 17TH CARBON WHERE A METHYL GROUP IS
BONDED TO IT, KNOWN AS C17-ALPHA ALKYLATION OR METHYLATION)
• IF UNMODIFIED & INGESTED ORALLY, THEY ARE METABOLIZED BY THE LIVER INTO INACTIVE METABOLITES
• GREATER RESISTANCE TO HEPATIC BREAKDOWN, RESULTS IN MORE TOXICITY AND STRAIN ON THE LIVER
By Pankaj Narsian
BRAIN
• PARANOID (EXTREME, UNREASONABLE) JEALOUSY AND EXTREME IRRITABILITY
• EXTREME MOOD SWINGS, STEROID RAGE
• ANGRY FEELINGS AND BEHAVIOR THAT MAY LEAD TO VIOLENCE
By Pankaj Narsian
GENDER SPECIFIC - MEN
• SHRINKING TESTICLES AND DECREASED SPERM COUNT
• BALDNESS
• DEVELOPMENT OF BREASTS
• INCREASED RISK FOR PROSTATE CANCER
By Pankaj Narsian
GENDER SPECIFIC – WOMEN
• GROWTH OF FACIAL HAIR OR EXCESS BODY HAIR
• MALE-PATTERN BALDNESS
• CHANGES IN OR STOP IN THE MENSTRUAL CYCLE
• ENLARGED CLITORIS AND DEEPENED VOICE
By Pankaj Narsian
FAQ
By Pankaj Narsian
ARE ANABOLIC STEROIDS ADDICTIVE
• EVEN THOUGH AAS DO NOT CAUSE THE SAME HIGH AS OTHER DRUGS, THEY CAN LEAD TO ADDICTION
• PEOPLE MAY CONTINUE TO ABUSE STEROIDS DESPITE PHYSICAL PROBLEMS, HIGH COSTS TO BUY THE DRUGS,
AND NEGATIVE EFFECTS ON THEIR RELATIONSHIPS. THESE BEHAVIORS REFLECT STEROIDS' ADDICTIVE
POTENTIAL
• RESEARCH HAS FURTHER FOUND THAT SOME STEROID USERS TURN TO OTHER DRUGS, SUCH AS OPIOIDS, TO
REDUCE SLEEP PROBLEMS AND IRRITABILITY CAUSED BY STEROIDS
By Pankaj Narsian
AAS VERSUS HGH
• ANABOLIC STEROIDS
•
•
•
MALE TRAITS
INCREASING STRENGTH
MUSCLE MASS
• HGH
•
•
•
CELL REPRODUCTION
REPLACEMENT OF CELLS
PROPER FUNCTIONING OF CERTAIN HORMONES AND ENZYMES, AND PROPER BRAIN FUNCTION
By Pankaj Narsian
TESTOSTERONE REFERENCE POINT
•
TESTOSTERONE IS UTILIZED AS THE MEASURING STICK WHEREBY ALL OTHER ANABOLIC STEROIDS ARE MEASURED AGAINST MUCH
LIKE THE REFERENCE OF TEMPERATURE FOR BOILING AND FREEZING POINT
•
UPON UNDERSTANDING THIS, ANY INDIVIDUAL CAN EASILY OBSERVE HOW A PARTICULAR GIVEN ANABOLIC STEROID POSSESSES
AN ANABOLIC STRENGTH THAT MIGHT BE SEVERAL TIMES STRONGER (OR WEAKER) THAN TESTOSTERONE
•
TESTOSTERONE’S ANABOLIC AND ANDROGENIC RATINGS ARE BOTH RESPECTIVELY 100
•
THE IMPORTANCE OF THE ANABOLIC AND ANDROGENIC STRENGTH RATINGS OF 100 RESPECTIVELY IS PARAMOUNT TO
UNDERSTANDING THE DIFFERENT STRENGTHS OF THE VARIOUS TYPES OF STEROIDS
By Pankaj Narsian
ROUTES OF ADMINISTRATION
• ORAL
• INJECTABLE
• DERMAL CREAM, GEL AND PATCHES
By Pankaj Narsian
STEROID WITHDRAWAL SYMPTOMS
• MOOD SWINGS AND FATIGUE
• RESTLESSNESS AND LOSS OF APPETITE
• SLEEP PROBLEMS AND DECREASED SEX DRIVE
• STEROID CRAVINGS
By Pankaj Narsian
BULKING AND CUTTING STEROIDS
• ANABOLIC STEROIDS DO NOT DIRECTLY BURN FAT
• SIMPLY IMPROVE NUTRIENT PARTITIONING WHICH MEANS THE EFFECT OF DIRECTING/SHUTTLING INGESTED
NUTRIENTS, VITAMINS, AND MINERALS TOWARDS MUSCLE REPAIR AND MUSCLE GROWTH TO A LARGE DEGREE
SO MUCH SO THAT FAT STORAGE IS EITHER COMPLETELY AVOIDED OR DRAMATICALLY REDUCED
• IT IS UNDERSTOOD THAT ANABOLIC STEROIDS DO INTERACT WITH ANDROGEN RECEPTORS ON FAT TISSUE TO
INITIATE LIPOLYSIS (FAT BREAKDOWN), BUT THIS DOES NOT OCCUR TO ANY SIGNIFICANT DEGREE
By Pankaj Narsian
BULKING AND CUTTING STEROIDS
•
THE ‘FAT BURNING’ PROPERTIES COMMONLY ASSOCIATED WITH ANABOLIC STEROIDS STEM FROM THE AFOREMENTIONED EXTREME
LEVEL OF NUTRIENT PARTITIONING THEY EXHIBIT. SOME TYPES OF STEROIDS EXHIBIT THIS AT A FAR GREATER DEGREE THAN ANY
OTHER ANABOLIC STEROID, ESPECIALLY ANABOLIC STEROIDS SUCH AS TRENBOLONE
•
EVEN TESTOSTERONE DOES THIS, WHERE CASES HAVE BEEN OBSERVED WHEREBY AN INDIVIDUAL ENGAGING IN THEIR FIRST-EVER
CYCLE OF TESTOSTERONE RESULTS IN THE GAINING OF LEAN MASS, AND A REDUCTION OF VARYING DEGREES OF BODY FAT
PERCENTAGE
•
OF COURSE, THE MOST PROMINENT DETAIL TO BE REMINDED OF IS THE FACT THAT RESULTS ARE 100% DEPENDENT ON THE
INDIVIDUAL’S NUTRITION AND TRAINING. DIFFERENT TYPES OF STEROIDS MERELY SERVE TO AMPLIFY THE EFFORTS AND HARD
WORK THAT THE NUTRITION AND TRAINING ASPECTS HAVE PROPERLY ESTABLISHED.
By Pankaj Narsian
CHEERS
By Pankaj Narsian