DNA & DNA Replication Webquest
Name:__________________________________________
Part 1: Interactive DNA Discovery
Use any of the links below to complete the Interactive DNA Discovery activity on the 23andMe website. Click Get Started
to begin and Next to move through the activity. As you move through the activity, answer the following questions.
Full URL: https://education.23andme.com/dna-discovery/#
Tiny URL: https://tinyurl.com/u4e8z6e
1. In which organelle is most DNA found?___________________________
2. How many chromosomes do you inherit from your father?_________
How many from your mother?_________
3. If you are male, what combination of chromosomes do you have?_________ If female?__________
4. What does DNA contain instructions for?_____________________________________________________________
5. What is the role of proteins?_______________________________________________________________________
6. What are the sections of DNA that contain instructions for making proteins called?___________________________
7. Does all of an organism’s DNA code for proteins?_______________
8. What does T pair with? __________ What does G pair with?___________
9. If a DNA sequence is A-T-G-A-C, write the sequence of base pairs that would pair with it._______________________
10. What percent of humans’ DNA sequences are identical? ________________
11. Can traits be determined by more than one gene?_____________________
12. What factors influence your traits?__________________________________________________________________
Part 2: DNA Structure and Function Video
Use any of the links below to watch the DNA Structure video by Teachers Pet. As you watch, answer the following
questions. Tiny URL: https://tinyurl.com/h55cdnx
Full URL: https://www.youtube.com/watch?v=C1CRrtkWwu0
13. What does DNA stand for?___________________________________________________________________
14. What does the information contained in DNA determine?__________________________________________
15. What does DNA code for?___________________________________
16. What are the monomers of DNA called?________________________
17. What are the four nitrogen bases contained in DNA?
Nucleotide
a. ________________________________
b. ________________________________
c. ________________________________
d.
________________________________
18. What phrase is used to describe the structure of DNA?____________________________
19. What is the backbone of DNA composed of? ___________________________________________________________
20. Which base pairs with adenine?______________________ Which base pairs with cytosine?____________________
DNA and DNA Replication Webquest
© Science Is Real
21. Label the phosphate and deoxyribose sugar. Then write the first initial of the complementary base pairs.
Write the full name of each base below its picture.
T
G
A
C
___________
___________
___________
___________
Helpful Hint!
Remember that Apples (A) go in a Tree (T) and Cars (C) go in a Garage (G).
Part 3: DNA Replication Base Pairing Practice Game
Use any of the following links to play the Replication Rush by NanoSpace game. As you play the game, follow directions
and answer the questions below. Full URL: http://nanospace.molecularium.com/attractions/replication_rush/
Tiny URL: https://tinyurl.com/k7s7r3o
Click Pair and read the diagram.
22. What does DNA have to do before a cell divides?____________________________________________________
23. Summarize the three steps of DNA replication.
1. ___________________________________________________________________________________________
2. ___________________________________________________________________________________________
3. ___________________________________________________________________________________________
24. Click Play to play the game. Play it a few times until you get the hang of it. Then write your best score, speed, and
the number of errors in the spaces below.
a) Score:______________
b) Speed:______________
c) Errors:______________
Part 4: DNA Replication Article
Use any link below to read the DNA Replication article from the CK12 website. As you read, answer the following
questions. Tiny URL: https://tinyurl.com/y8pecyme
Full URL: https://www.ck12.org/book/cbse_biology_book_class_xii/section/7.4/
25. In which phase of the cell cycle does DNA replicate? ____________________________________________________
26. Explain why DNA replication is a semi-conservative process. _____________________________________________
_______________________________________________________________________________________________
27. What is the role of DNA helicase? ___________________________________________________________________
28. Which enzyme reads and builds a complementary strand of DNA? _________________________________________
29. What is the lagging strand synthesized by? _________________________
30. Which enzyme attaches the Ozaki fragments?_______________________
DNA and DNA Replication Webquest
© Science Is Real
Part 5: DNA Replication Video
Use any link below to watch the DNA Replication video by the Amoeba Sisters. Answer the questions below as you
watch. Full URL: https://www.youtube.com/watch?v=Qqe4thU-os8&t=74s
Tiny URL: https://tinyurl.com/yc7teo82
31. Why does DNA have to replicate? ___________________________________________________________________
32. What do enzymes have the ability to do? _____________________________________________________________
Fill in the table below with information from the video.
Enzyme
Enzyme Nickname
33. Helicase
Functions
34. DNA Polymerase
35. Primase
36. Ligase
37. What is the name of the part of DNA where DNA replication starts?________________________________________
38. What binds to the DNA strands to keep them separated?________________________________________________
39. What is the role of topoisomerase?__________________________________________________________________
40. In which direction does the DNA Polymerase build a new strand? __________________________________________
41. Why is the new strand named the lagging strand? ______________________________________________________
42. What could happen is DNA Polymerase matches the wrong DNA bases? ____________________________________
Part 6: DNA Replication Fork Labeling Activity
Use any of the following links to complete the DNA Fork Labeling Activity on the Purpose Games website. Play the game
over until you get a 86% or higher score. When you are finished, answer the questions below.
Full URL: https://www.purposegames.com/game/1950
Tiny URL: https://tinyurl.com/y9zbfhm4
43. Write your final best score on the line to the right. ___________________
Your teacher may require that you submit a screenshot to prove your score.
44. Identify the name of each structure on the Replication Fork Diagram.
1. ___________________________
DNA Replication Fork
2. ___________________________
3. ___________________________
4. ___________________________
5. ___________________________
6. ___________________________
7. ___________________________
8. ___________________________
9. ___________________________
10. ___________________________
11. ___________________________
DNA and DNA Replication Webquest
BONUS REVIEW GAME!
https://quizizz.com/join/quiz/581749cf019565a82c71e9a6/
start?from=soloLinkShare
Tiny URL: https://tinyurl.com/yccs2244
© Science Is Real