Pharmacotherapy: A Pathophysiologic Approach, 10e >Allergic Rhinitis
Joseph T. DiPiro, Robert L. Talbert, Gary C. Yee, Gary R. Matzke, Barbara G. Wells, L. Michael Posey+
TABLE 95-5Relative Adverse-Effect Profiles of Antihistamines
Medications
Relative Sedative Effects
Relative Anticholinergic Effects
Alkylamine class, nonselective
Brompheniramine maleate
Low
Moderate
Chlorpheniramine maleate
Low
Moderate
Dexchlorpheniramine maleate
Low
Moderate
Carbinoxamine maleate
High
High
Clemastine fumarate
Moderate
High
Diphenhydramine hydrochloride
High
High
High
High
Low
Moderate
Azelastine (nasal only)
Low to none
Low to none
Bepotastine (ophthalmic only)
Low to none
Low to none
Cetirizine
Low to moderate
Low to none
Levocetirizine
Low to moderate
Low to none
Desloratadine
Low to none
Low to none
Fexofenadine
Low to none
Low to none
Loratadine
Low to none
Low to none
Olopatadine (nasal only)
Low to none
Low to none
Ethanolamine class, nonselective
Phenothiazine class, nonselective
Promethazine hydrochloride
Piperidine class, nonselective
Cyproheptadine hydrochloride
Phthalazinone class, peripherally selective
Piperazine class, peripherally selective
Piperidine class, peripherally selective
Date of download: 02/10/22 from AccessPharmacy: accesspharmacy.mhmedical.com, Copyright © McGraw Hill. All rights reserved.