Terms from DNA Notes Rosalind Franklin – used x-rays to figure out that DNA is a double helix Erwin Chargaff – determined that the amount of Adenine =amount of Thymine and the amount of Cytosine = amount of Guanine in DNA James Watson and Francis Crick – won Nobel prize for discovering the structure of DNA Semi-conservative model of DNA replication – new piece of DNA is half “original” DNA and half new DNA 3 parts of a DNA nucleotide – sugar (deoxyribose), phosphate, nitrogenous base (A,T,C, or G) DNA and RNA are what type of macromolecule? – nucleic acids 4 DNA bases – Adenine, Thymine, Cytosine, Guanine Deoxyribose – sugar in DNA Purines – double ringed bases (adenine and guanine) Pyrimidines – single ringed bases (cytosine and thymine) Replication – process by which DNA is copied Bonds with Adenine in DNA - Thymine Nucleosome – structure in chromatin consisting of DNA wrapped around a histone protein Histone – a protein that binds to DNA Chromatin – DNA and proteins – found in the nucleus Chromosome – structure made up of tightly coiled chromatin Make up the backbone of DNA – sugar (deoxyribose) and phosphate Terms from RNA/Protein Synthesis Notes 3 differences between DNA and RNA – Sugar (deoxyribose(DNA) vs. ribose(RNA)), RNA uses Uracil instead of Thymine, RNA is single stranded – DNA is double stranded Bonds with Adenine in RNA - Uracil Ribose - sugar found in RNA Three types of RNA – mRNA, tRNA, rRNA Function of mRNA – bring DNA code to ribosome Function of tRNA – bring amino acids to the ribosome as the mRNA code is read Function of rRNA – makes up ribosomes Transcription – process of making an RNA copy from DNA Translation – ribosome reading the mRNA code to make proteins Codon – three bases that code for an amino acid found on mRNA Anti-codon – found on tRNA, three bases that match up with the codon Genetic Code – DNA and RNA Building blocks of Proteins – amino acids Polypeptide- a chain of amino acids Number of possible codons - 64 AUG- start codon Stop codons – UGA, UAA, UAG Number of possible amino acids - 20 The bond between amino acids – peptide bond Polypeptides can combine to form these - proteins Type of RNA that contains codons - mRNA Type of RNA that contains anti-codons - tRNA Why is transcription necessary? – to make multiple copies of DNA so proteins can be made faster