DNA – The Code for Life Question: Why don’t we all look alike? All Living Things… Have cells. All cells contain the genetic instructions that make an organism unique. Adapted to environment, appearance, preferences, behaviors, survival instincts, etc. DNA We get our genetic codes or instructions from DNA that is located inside every cell. DNA DNA stands for – Deoxyribonucleic acid Functions of DNA: 1. Carries the codes to make proteins. 2. Carries the genetic material that is passed on from the parents to the offspring. Discovery of DNA Rosalind Franklin - Invented X-ray diffraction photography. Photo used to determine the shape of DNA is spiral. DISCOVERY OF DNA James Watson and Francis Crick used the information from Franklin and other scientists to build a 3-D model of DNA. Won the Nobel Peace Prize in Chemistry in 1961. Structure of DNA Shape of DNA - Like a twisted rope ladder. This shape is called Double Helix. A single spiral would be called Helix. STRUCTURE OF DNA Side Pieces (The Rope Part) Are alternating units of sugar and phosphate groups. These go down both sides of the molecule phosphate Sugar (called deoxyribose) STRUCTURE OF DNA Nitrogen Bases (Steps of the ladder) 1. 2. 3. 4. Adenine – A Thymine – T Cytosine – C Guanine - G The bases are connected to the sugar only !!!!! STRUCTURE OF DNA The nitrogen bases fit together in this way: Adenine always goes with Thymine Cytosine always goes with Guanine phosphate adenine sugar thymine cytocine guanine STRUCTURE OF DNA These three parts form the basic unit of DNA called the NUCLEOTIDE. (subunits of DNA) phosphate Sugar (deoxyribose) Nitrogen base Can be A, T, C or G DNA Nucleotide Drawing Where is DNA located? DNA molecules are coiled up inside of EVERY SINGLE CELL! The structures that DNA is coiled into are called CHROMOSOMES. This is how the DNA molecules actually fit inside of tiny cells. CHROMOSOME ARRANGEMENT All regular body cells have all the same parts in multi-cellular organisms and the same # of chromosomes.in human body There are 46 chromosomes cells; 23 pairs. Chromosomes always come in pairs. 22 of the pairs are similar. The 23rd pair is different. These are the sex chromosomes. Male xy NUMBERS OF CHROMOSOMES VS COMPLEXITY The number of chromosomes in the cells of eukaryotes differs from one kind of organism to another and has NOTHING to do with the complexity of the organism. FOR EXAMPLE: Goldfish - 98 Wheat - 42 Human - 46 Potato - 48 Fruit fly - 8 A fern called Ophioglossum reticulatum has 1,260 chromosomes per cell, more than any other known Gene: segment of DNA on your chromosomes that determines your traits. Traits • Characteristics about an organism that are determined by the information carried on genes (segments of DNA). How does DNA copy itself? DNA copies itself to ensure that each new cell that is produced gets the correct number of chromosomes and receives an EXACT copy of the DNA molecule. This is called DNA REPLICATION. The DNA molecule serves as its own pattern or template so as an exact copy can be made. DNA REPLICATION What if there is a mistake? There is always a chance that the wrong nucleotide bonds to another. HOWEVER, DNA has a special enzyme that is responsible for “reading” the bases and recognizing and replacing damaged or wrong nucleotides. This PROOFREADING allows for only one (1) error in ONE BILLION nucleotides. What happens when there is a problem during replication? A permanent change in the sequence of DNA is known as a mutation Not all mutations are bad. Common mutations (in humans) Pimples/acne, high fertility (twins), heart disease, diabetes, stroke, high blood pressure, color blindness, heterochromia (two different colors in one eye OR two different colored eyes), red hair, down syndrome, blue eyes, freckles DNA – The Code for Life Notes All Living Things Structure of DNA • • • Shape of DNA: • Like a _____________________rope ladder. • This shape is called double _____________. • Side Pieces (The Rope Part) - Are alternating units of ________________and phosphate groups. These go down ____________sides of the molecule. • Nitrogen Bases ( The steps of the ladder) • Adenine • Thymine • C__________________ • Guanine • The Nitrogen Base pairs fit together in this way: Have ______________ All cells contain the __________________ instructions that make an organism unique. DNA • • • We get our genetic codes or ___________________from _____________ that is located inside every cell. DNA stands for – Deoxyribonucleic ___________ Functions of DNA: • Carries the codes to make ______________ • Carries the genetic material that is passed on from the ___________________to the offspring. Discovery of DNA • Rosalind Franklin - Invented ___________ diffraction photography. Photo used to determine the shape of DNA is ___________________, • James Watson and Francis Crick used the information from Franklin and other scientists to build a 3-D model of DNA. • Won the Noble Prize in Chemistry in 1961. Adenine always goes with Thymine Cytosine always goes with Guanine Structure of DNA • These three parts form the basic unit of DNA called the __________________ (subunits of DNA) Chromosome Arrangement • 22 of the pairs are ___________________, and the 23rd pair is different • The different chromosomes are the sex chromosomes • Male xy and Female ______ Where is DNA located? • • DNA molecules are ___________ up inside of EVERY SINGLE CELL! The structures that DNA is coiled into are called CHROMOSOMES This is how the ___________ molecules fit inside of __________ cells. Chromosome Arrangement • • • All ______________body cells have all the same parts in multi-cellular organisms and the same # of chromosomes. There are _______chromosomes in human body cells; 23 pairs. _________________________ always come in pairs. • • Gene – segment of _________ on your chromosomes that determine your ___________ Traits - Characteristics about an _______________ that are determined by the information carried on genes (segments of DNA). How does DNA copy itself? • DNA copies itself to ensure that each new cell that is produced gets the correct number of chromosomes and receives an EXACT copy of the DNA molecule; this is called DNA Replication. What happens when there is a problem during replication? • • A permanent change in the sequence of DNA is known as a mutation Not all mutations are bad.