Build a Monoclonal Antibody Task Step 1: Pick a Scenario Step 2: Choose your monoclonal antibody Step 3: Accessorise your antibody Develop an antibody for each scenario then look at the answer table to check the result. Scenario A: Your antibody binds to the tumour and makes it glow. The patient is not helped by this. Scenario B: Your antibody binds to the blood vessel wall with a fluorescent dye attached, enabling you to get a good look at it. Scenario C: Your antibody binds to harmless bacteria and glows. This gives false-positive result for chlamydia. Scenario A: Your antibody binds to the tumour and kills it without harming the patient Scenario B: Your antibody binds to the blood vessel wall and kills its cells. Scenario C: Your antibody binds to harmless bacteria and kills them. This does not tell you whether the sample had chlamydia in it. Scenario A: Your antibody binds to the tumour but does nothing. The patient is not helped by this. Scenario B: Your antibody binds to the blood vessel wall but you don’t see anything. Scenario C: Your antibody binds to harmless bacteria but you don’t see anything. Scenario A: The antibody does not bind to anything. Scenario B: Your antibody binds to the blood vessel wall with a fluorescent dye attached, enabling you to get a good look at it. Scenario C: The antibody binds to chlamydia and glows. This antibody can detect the presence of chlamydia in a sample. Scenario A: The antibody does not bind to anything. Scenario B: Your antibody binds to the blood vessel wall and kills its cells. Scenario C: The antibody binds to chlamydia cells and kills them, but this does not tell you whether or not there was chlamydia in the sample. Scenario A: The antibody does not bind to anything. Scenario B: Your antibody binds to the blood vessel wall but you don’t see anything. Scenario C: Your antibody binds to chlamydia but you do not see anything. This does not tell you whether the sample has chlamydia in it. Scenario A: Your antibody binds to both the tumour and the healthy cells, and makes them glow. The patient is not helped by this. Scenario B: Your sample binds to red blood cells and makes them glow. Unfortunately, it wasn’t red blood cells you were looking for. Scenario C: Your antibody binds to harmless bacteria and glows. This gives false-positive result for chlamydia. Scenario A: Your antibody binds to both the tumour and the healthy cells, harming both. Scenario B: Your antibody binds to red blood cells and kills them. This does not help you to see the blood vessel cell walls. Scenario C: Your antibody binds to harmless bacteria and kills them. This does not tell you whether the patient’s sample had chlamydia in it. Scenario A: Your antibody binds to both the tumour and the healthy cells, but does nothing. The patient is not helped by this. Scenario B: Your antibody binds to red blood cells and does nothing Scenario C: Your antibody binds to harmless bacteria but you don’t see anything.