Lock and Key Model Lyrics All I Want for Christmas tune Video Concept Lip Sync I. Models of enzyme actions The lock and key model Models of enzyme actions The induced fit model I. Normal lip sync II. We’ll discuss it in a while Listen it will be just fine Don’t forget to smile Our presentation will start now II. Normal lip sync Normal lip sync Gesture “no” and “smile” Gesture “our” and “now” III. Enzymes are proteins that speeds up Reactions and breaks down substrate It is very specific and Only works with right substrate III. Happy lip sync HAHAHAHA Through out this verse IV. Substrate is a molecule That is broken by an enzyme Active site is where the substrate Molecules fit in an enzyme IV. Happy lip sync agaaain V. Just as a lock accepts the correct keys Enzymes accepts specific substrates What mechanism is this? The lock and key mechanism V. Show keys on the “keys” word HAHAHA VI. Oh, lock-key model was proposed by Fisher in 1894 It was on of the earliest model Proposed for enzyme actions VI. Lip sync with snap VII. Substrate plus enzyme is equal To enzyme substrate complex It will produce a new product Molecule produce in reaction VII. Lip sync with snap VIII. There’s some factors that affect enzyme rate The temperature and pH What more can we know? Oh baby, this is lock and key model VIII. Stop snap IX. Oh, when not in right condition Active site’s shape will change When denurated the substrate would not fir It would not break the substrate The substrate would not break down Santa, won’t it break if it has different shape Won’t you please fit it for me? IX. Lip sync Repeat verse V then proceed to verse VI Outro: the lock and key mechanism Gesture “questioning” Gesture “proud as if you know it” HAHAHA HIGH ENERGY HIGH ENERGY