PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
The study of virus is called ______________________
A. Virology
B. Mycology
C. Virulence
D. None of the above
CORRECT ANSWER
A
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
Which of the following is not true of virus ?
A. They can contain both DNA and RNA
B. They contain a protein coat that surrounds the nucleic acid
C. Multiply inside a living cell using the synthetic machinery of the
Host cell
CORRECT ANSWER
D. Cause synthesis of specialized elements that can
Transfer the nucleic acid to another cell
A
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
Which of the following is true of virus ?
A. They are not cells
B. They are both living and non-living
C. They are obligate intracellular parasite which means they can only
Reproduce inside a host
CORRECT ANSWER
D. All of the above
D
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
About the diameter and size of viruses which of the following is
wrong
A. Most virus vary in diameter from 20nm to 400nm in diameter
B. The largest measures about 500nm
C. They are about 100 times larger than bacteria
D. They can only be observed with electron microscope
CORRECT ANSWER
C
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
Virus are composed of
A. Nucleic acid, protein and lipid component
B. Nucleic acid and protein
C. Nucleic acid and carbohydrate
D. Nucleic acid and lipids
CORRECT ANSWER
B
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
The genome (nucleic acid) is surrounded by a protein shell coat
called
A. Capsid
B. Nucleocapsid
C. Virion
D. Envelope
CORRECT ANSWER
A
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
The genome and capsid are called
A. Capsid
B. Nucleocapsid
C. Virion
D. Envelope
CORRECT ANSWER
B
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
Most virus have addition covering of lipids around the nucleocapsid
Known as
A. Capsid
B. Nucleocapsid
C. Virion
D. Envelope
CORRECT ANSWER
D
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
The complete viral particle is called _____________
A. Capsid
B. Nucleocapsid
C. Virion
D. Envelope
CORRECT ANSWER
C
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
The capsid compose of protein sub unit called
A. Capsomere
B. Nucleocapsid
C. mRNA
D. All of the above
CORRECT ANSWER
A
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
About the nucleic acid found in virus
A. RNA are always single stranded
B. DNA are usually double stranded
C. Some RNA are also double stranded but are not common
D. All of the above
CORRECT ANSWER
D
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
Give two functions of the capsid
To protect the genome from external harmful factors or agent
1. _______________________________________________________
It introduces the genome into the host cells
2. _______________________________________________________
CORRECT ANSWER
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
Complete the missing part
1. Depending on the virus, envelope may or may not be covered by
_____a_______. The _____b_____ are _____c______ that projects
from The surface of the envelope.
CORRECT ANSWER
a. Spikes
b. Spikes c. Carbohydrate - protein complexes
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
Complete the missing part
1. Some virus like HIV virus have viral envelope covering the capsid.
The envelope is made up of _____a______ and _____b_____ derive
From Portion of the host ______c_________, but also include some
viral glycoprotein
CORRECT ANSWER
a. Lipids
b. Proteins c. Cell membrane(phospholipids)
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
Spikes helps some viruses to clump red blood cells by binding to the
Red blood cells and forming a bridge between them. This is known as
A. Agglutination
B. Haemagglutination
C. Coagulation
D. Viral clumping
CORRECT ANSWER
B
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
Complete the missing part
1. Viruses whose capsid are not covered with envelop are known as
_________________
2. Envelope aid the virus to infect new cells by fusion of the envelope
With the host cell or plasma membrane but envelope are not damaged
Easily. True or false
1. Naked virus
2. False
CORRECT ANSWER
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
Virus can have any of the following shape except
A. Helical
B. Icosahedral (Isometric)
C. Complex
D. Linear
CORRECT ANSWER
D
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
Complete the missing part
1. Viral proteins can be classified into ______________ and ________
CORRECT ANSWER
Structural and non-structural (functional)
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
Complete the missing part
1. Structural protein are the protein present in ______________while
_______________ and ______________ are known as non-structural
Or functional proteins
2. Hemagglutinins are present in viruses such as togavirus, picornavirus
Myxovirus, adenoviruses and papoviruses because
CORRECT ANSWER
1. Coat of the virus
Hemagglutinins and enzymes 2. of the glycoprotein present in envel.
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
Which of the following is not a class of enzyme present in viruses
A. Neuraminidases
B. RNA Polymerases
C. Reverse transcriptase
D. Enzymes of cellular origin
E. Lactate dehydrogenase
CORRECT ANSWER
E
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
About preservation of virus infertility, indicate true or false in each
Of The options
A. Virus can survive for seconds at 𝟔𝟎 𝟎 𝑪. For minutes at 𝟑𝟕 𝟎 𝑪.
For hours at 𝟐𝟎 𝟎 𝑪, days at 𝟒 𝟎 𝑪. And years at −𝟕𝟎 𝟎 𝑪.
B. They prefer physiological PH as prevalent in humans 7.4
C. Lipid solvent like chloroform and ether. Other solvent and
Detergent destroys them
D. All of the above are true
CORRECT ANSWER
D
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
Infection and replication of virus can be divided into stages list them
1.
Attachment of virus to host cell (Adsorption)
________________________________________________________
2.
Penetration or entry
________________________________________________________
3.
Uncoating
________________________________________________________
4.
Transcription of early m RNA
________________________________________________________
________________________________________________________
5.
Translation of early proteins
6.
Replication of viral genome
________________________________________________________
7.
Transcription of late mRNA
________________________________________________________
________________________________________________________
8.
Translation of late protein
9.
Assembly of virion
________________________________________________________
10. Release
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
Which of the following is not possible mechanism which the virus
Enters the host cells
A. Translocation
B. Endocytosis
C. Fusion
D. Direct fusion of the virus envelope with host cell membrane
E. None of the above
CORRECT ANSWER
E
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
Which of the following is not possible mechanism which the virus
Enters the host cells
A. Translocation
B. Endocytosis
C. Fusion
D. Direct fusion of the virus envelope with host cell membrane
E. None of the above
CORRECT ANSWER
E
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
Which of the following has a single stranded DNA
A. Picornaviruses
B. Parvoviruses
C. Togaviruses
D. Poxviruses
E. None of the above
CORRECT ANSWER
B
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
Which of the following virus is not an example of RNA virus
A. Picornaviruses
B. Retroviruses
C. Togaviruses
D. Adenovirus
E. Paramyxoviruses
CORRECT ANSWER
D
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
Which of the following about picornaviruses are wrong
A. They are enveloped single stranded viruses
B. They are icosahedral in shape
C. They are resistant to many chemicals
D. Two examples are enterovirus and rhinovirus
E. None of the above
CORRECT ANSWER
A
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
Which of the following viruses causes common cold
A. Enterovirus
B. Togavirus
C. Rhinovirus
D. Retrovirus
E. None of the above
CORRECT ANSWER
C
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
Example of enterovirus are or is
A. Coxsakie virus
B. Polio virus
C. Echo virus
D. All of the above
E. None of the above
CORRECT ANSWER
D
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
Which of the following can inactivate enterovirus
A. Hydrochloric acid
B. Chlorine
C. Drying
D. All of the above
E. None of the above
CORRECT ANSWER
D
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
About rhinovirus which of the following is not true
A. They cause common cold
B. They replicate in the epithelial cells of the upper respiratory tract
C. They can withstand the acidic nature of the stomach
D. All of the above
E. None of the above
CORRECT ANSWER
C
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
Which of the following viruses causes dengue fever
A. Togavirus
B. Parvovirus
C. Picornavirus
D. Retrovirus
E. None of the above
CORRECT ANSWER
A
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
Which of the following viruses causes mump, measles, viral
pneumonia and bronchitis in children
A. Togavirus
B. Parvovirus
C. Picornavirus
D. Retrovirus
E. Paramyxoviruses
CORRECT ANSWER
E
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
About the retroviruses
A. They are enveloped single stranded RNA viruses
B. They are helical in shape
C. They use their own reverse transcriptase to transcribe their RNA
Into DNA in the cytoplasm of the host cell
D. Examples is DNA virus
E. All of the above
CORRECT ANSWER
E
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
Several molecules of DNA are incorporated into host chromosomes
Such DNA is referred to as a
A. Porvirus
B. Provirus
C. Poxvirus
D. None of the above
E. All of the above
CORRECT ANSWER
B
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
Which among the following is not a DNA virus
A. Adenovirus
B. Herpes virus
C. Poxvirus
D. Papovaviruses
E. Picornaviruses
CORRECT ANSWER
E
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
The virus that cause severe pneumonia is
A. Adenovirus
B. Herpes virus
C. Poxvirus
D. Papovaviruses
E. Picornaviruses
CORRECT ANSWER
A
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
Parvoviruses are classified into
A. Parvoviruses
B. Dependoviruses
C. A and B
D. None of the above
CORRECT ANSWER
C
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
Which of the following viruses enlist an unrelated helper virus or a
Divided host cell
A. Parvoviruses
B. Poxvirus
C. A and B
D. None of the above
CORRECT ANSWER
A
PHARMACEUTICAL MICROBIOLOGY
MCQ EXAM PREP
Which of the following viruses enlist an unrelated helper virus or a
Divided host cell
A. Parvoviruses
B. Poxvirus
C. A and B
D. None of the above
CORRECT ANSWER
A