EKG - Lecture 1 ● EKG - Lecture 2 ● Asymmetric T wave inversion - Heart strain ● Tension pneumothorax with mediastinal shift--poor R wave progression ● Digoxin Toxicity--second degree block type 1 ● Azithromycin/levaquin--long QT syndrome EKG - Lecture 3 ● Irregularly irregular - Atrial Fibrillation ● Wavy baseline - Atrial Fibrillation ● “Camel hump”/biphasic p wave--premature atrial complex Hypertension ● Hourglass appearance - AV nicking Vascular Disease ● Scapular Pain--Aortic dissection ● “Blue toe syndrome”--PVD ● Gangrene--PVD ● Hemiparesis--Aortic dissection ● Phosphodiesterase inhibitors--PVD tx ● Focal areas of discoloration: pallor/white w/ elevation, red w/ lowering--PVD Valvular Disorders ● Widened Pulse Pressure - Aortic regurgitation ● Best heard leaning forward at end expiration—AR ● Heard after S2 before S1–AR ● Apical impulse displaced laterally—AR ● Hyperparathyroidism—mitral stenosis ● Symptom onset young (3rd or 4th decade of life)—mitral stenosis ● Systolic ejection murmur between S1 and S2- AS ● De Musset Sign--Aortic regurgitation ● Muller Sign--Aortic regurgitation ● Quickens pulses--Aortic regurgitation ● Ortner’s Syndrome--Mitral stenosis ● Double density on CXR-mitral stenosis ● Opening snap - Mitral stenosis (murmur) ● Mid to late systolic click- MVP ● Fen-phen (appetite suppressant) --risk factor for aortic regurgitation ● Osteogenesis imperfecta--mitral valve prolapse ● Hyperparathyroidism-causes calcific mitral stenosis ● Crackles/rales--mitral regurgitation ● Holosystolic murmur - mitral regurgitation ● Cancer radiation therapy--causes calcific mitral stenosis ● Pulsus Parvus Tardus - Aortic stenosis ● High mortality with valve replacement—tricuspid stenosis ● ● ● Found in 70% of the population—tricuspid regurgitation Tricuspid annuloplasty—tricuspid regurgitation tx Lift in right ventricle--Mitral stenosis Traumatic, Infectious, and Inflammatory Heart Conditions: ● Febrile patient with a new heart murmur--infectious endocarditis ● Fever of unknown origin—infective endocarditis ● Night sweats—infective endocarditis ● Chronic hemodialysis, poor dentition—risk factors for infectious endocarditis ● Tricuspid valve most commonly affected—infective endocarditis ● Janeway lesions-Infectious endocarditis ● Osler’s nodes-infectious endocarditis ● Roth spots-infectious endocarditis ● Splinter hemorrhages-Infectious endocarditis ● Modified Duke Criteria--infectious endocarditis diagnostic criteria ● Vegetation on valves - infectious endocarditis ● Most common disorder involving the pericardium—pericarditis ● Occurs in young patients <50–acute pericarditis ● Dressler Syndrome--post-MI pericarditis ● Sharp, pleuritic chest pain relieved by sitting forward--pericarditis ● Colchicine--acute pericarditis tx ● TB infection--Constrictive pericarditis ● Pericardial friction rub--acute pericarditis ● Calcified pericardium--constrictive pericarditis ● Prednisone/pericardectomy--constrictive pericarditis tx ● Pericardial knock--constrictive pericarditis ● Muffled heart sounds-pericardial effusion ● Unexplained cardiomegaly—pericardial effusion ● Isolated left pleural effusion—pericardial effusion ● Low QRS voltage with cyclic beat-to-beat shift in QRS axis--pericardial effusion ● Electrical alternans—pericardial effusion ● Chest heaviness--pericardial effusion ● Enlarged cardiac silhouette--pericardial effusion ● Obstructive shock—cardiac tamponade ● Right ventricular collapse--cardiac tamponade ● Malignancy—main cause of tamponade ● Beck’s triad (hypotension, distant or muffled heart sounds, JVD)--Cardiac tamponade ● Pulsus paradoxus--Cardiac tamponade ● “Water bottle shaped heart”--cardiac tamponade ● Dobutamine—cardiac tamponade tx Cardiomyopathies ● S3 sound--dilated cardiomyopathy OR restrictive cardiomyopathy ● ● ● ● ● S4 sound--hypertrophic cardiomyopathy Increased septum to wall ratio--hypertrophic cardiomyopathy Septal myectomy--hypertrophic cardiomyopathy Alcohol septal ablation-hypertrophic cardiomyopathy Exercise induced arrhythmias—HOCM Congenital ● S2 split with expiration--bicuspid aortic valve ● Cryptogenic stroke/migraines—patent foramen ovale (ostium secundum) ● Mitral valve leaflet cleft—ostium primum ● Crux of the heart—ostium primum ● Wide and fixed splitting of S2–atrial septal defect ● Most common congenital heart defect—ventricular septal defect ● Biventricular enlargement on echo—VSD ● Grunting/retractions in a newborn—patent ductus arteriosus ● Continuous, machinery-like murmur—patent ductus arteriosus ● Maternal diabetes, maternal rubella, maternal alcohol/phenytoin use—VSD ● Common in prematurity—patent ductus arteriosus ● Catheter-based closure/surgical ligation—patent ductus arteriosus ● Tx with COX inhibitors (ibuprofen)—patent ductus arteriosus ● Early cyanosis present at birth—transposition of the great arteries ● Tx with prostaglandin—transposition of the great arteries OR aortic coarctation ● Balloon septostomy—transposition of the great arteries ● Arterial switch procedure—transposition of the great arteries ● Radial pulses bounding, femoral/popliteal pulses weak—aortic coarctation ● Liver/spleen edges palpable below costal margin—aortic coarctation ● Hypercyanotic episodes/“tet spells”—tetralogy of fallot ● Loud S2–tetralogy of fallot ● Poor nutrition during pregnancy, maternal age >40–tetralogy of fallot ● Boot shaped heart—tetralogy of fallot ● Heart failure by 6 weeks of age--complete AV septal defect ● Right-sided aortic arch and knob - tetralogy of fallot ● WANT ductus arteriosus to remain open Heart Failure ● Kerley B lines, cephalization, pleural effusion, cardiomegaly—HF CXR findings ● BNP >500 ● Hyponatremia on CMP—severe HF ● <2G sodium per day ● 1.5-2L fluid per day ● Cardiac resynchronization therapy/biventricular pacing—HF tx ● JVP rise >4cm on hepatojugular reflex ● Anorexia nervosa from systemic congestion ● Displaced PMI from LVH ● ● ● ● ● S3 Check liver function tests because liver could be affected by hepatic congestion Metabolic syndrome--risk factor for HF HTN--biggest risk for HF TSH--High OR low can precipitate HF--check when doing workup Hypotension/Shock ● Morning cortisol—check for orthostatic hypotension ● Head-up tilt table testing—orthostatic hypotension ● Small frequent meals—tx for orthostatic hypotension ● Fludrocortisone—tx for orthostatic hypotension ● Isometric counter-pressure—tx of vasovagal syncope ● “Wet and cold shock”—cardiogenic shock (pulmonary edema is wet, extremities are cold) ● Oliguria—cardiogenic shock ● Metabolic acidosis/high serum lactate levels—cardiogenic shock ● Vasopressors—tx for cardiogenic shock