Chapter 18 The Circulatory System: Blood Answer Key
True / False Questions
1.
Hemostasis is the production of formed elements of blood.
FALSE
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Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K04.01 Distinguish between the terms hemostasis and coagulation.
HAPS Topic: Module K04 Hemostasis, including coagulation of blood.
Learning Outcome: 18.05a Describe the bodys mechanisms for controlling bleeding.
Section: 18.05
Topic: Hemostasis, including coagulation of blood
2.
Blood viscosity stems mainly from electrolytes and monomers dissolved in plasma.
FALSE
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Blooms Level: 2. Understand
Gradable: automatic
HAPS Objective: K02.01 Describe the overall composition of plasma, including the major types of plasma proteins, their functions and
where in the body they are produced.
HAPS Topic: Module K02 Composition of blood plasma.
Learning Outcome: 18.01d Explain the significance of blood viscosity and osmolarity.
Section: 18.01
Topic: Composition of blood plasma
3.
Lymphoid hemopoiesis occurs mainly in the bone marrow.
FALSE
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Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K03.02c With respect to development of formed elements, discuss the difference in leukopoiesis of granulocytes and
agranulocytes.
HAPS Topic: Module K03 Identity, microscopic anatomy, numbers, formation, and functional roles of the formed elements of blood.
Learning Outcome: 18.04c Describe the formation and life history of leukocytes.
Section: 18.04
Topic: Functional roles of formed elements of blood
Topic: Microscopic anatomy of formed elements of blood
4.
Oxygen and carbon dioxide bind to different parts of hemoglobin.
TRUE
18-!1
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Accessibility: Keyboard Navigation
Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K03.03b With respect to the functional roles of formed elements, discuss the structure and function of hemoglobin, as
well as its breakdown products.
HAPS Topic: Module K03 Identity, microscopic anatomy, numbers, formation, and functional roles of the formed elements of blood.
Learning Outcome: 18.02b Describe the structure and function of hemoglobin.
Section: 18.02
Topic: Functional roles of formed elements of blood
5.
The liver stores excess iron in ferritin.
TRUE
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Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K03.03b With respect to the functional roles of formed elements, discuss the structure and function of hemoglobin, as
well as its breakdown products.
HAPS Topic: Module K03 Identity, microscopic anatomy, numbers, formation, and functional roles of the formed elements of blood.
Learning Outcome: 18.02d Describe the cycle of erythrocytes.
Section: 18.02
Topic: Functional roles of formed elements of blood
6.
The most important components in the cytoplasm of RBCs are hemoglobin and carbonic anhydrase.
TRUE
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Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K03.03a With respect to the functional roles of formed elements, state the function of red blood cells.
HAPS Topic: Module K03 Identity, microscopic anatomy, numbers, formation, and functional roles of the formed elements of blood.
Learning Outcome: 18.02a Discuss the structure and function of erythrocytes (RBCs).
Section: 18.02
Topic: Functional roles of formed elements of blood
Topic: Microscopic anatomy of formed elements of blood
7.
A person develops anti-A antibodies only after he is exposed to antigen A, and anti-B antibodies only
after he is exposed to antigen B.
FALSE
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Blooms Level: 2. Understand
Gradable: automatic
HAPS Objective: K05.04 Distinguish between the development of anti-Rh antibodies and the development of anti-A and anti- B
antibodies.
HAPS Topic: Module K05 ABO and Rh blood grouping.
Learning Outcome: 18.03a Explain what determines a persons ABO and Rh blood types and how this relates to transfusion compatibility.
Section: 18.03
Topic: ABO and Rh blood grouping
18-!2
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8.
Incompatibility of one person's blood with another results from the action of plasma antibodies
against the RBCs' antigens.
TRUE
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Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K05.01 Explain the role of surface antigens on RBCs in determining blood groups.
HAPS Topic: Module K05 ABO and Rh blood grouping.
Learning Outcome: 18.03a Explain what determines a persons ABO and Rh blood types and how this relates to transfusion compatibility.
Section: 18.03
Topic: ABO and Rh blood grouping
9.
Rh incompatibility between a sensitized Rh
the newborn.
FALSE
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Blooms Level: 3. Apply
Gradable: automatic
HAPS Objective: K05.05 Predict which blood types are compatible and what happens when the incorrect ABO or Rh blood type is
transfused.
HAPS Topic: Module K05 ABO and Rh blood grouping.
Learning Outcome: 18.03c Describe the effect of a blood type incompatibility between mother and fetus.
Section: 18.03
Topic: ABO and Rh blood grouping
10.
Circulating WBCs spend most of their lives in the bloodstream.
FALSE
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Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K03.03c With respect to the functional roles of formed elements, describe functions for each of the five major types of
leukocytes as well as the two major subtypes of lymphocytes (T and B).
HAPS Topic: Module K03 Identity, microscopic anatomy, numbers, formation, and functional roles of the formed elements of blood.
Learning Outcome: 18.04c Describe the formation and life history of leukocytes.
Section: 18.04
Topic: Functional roles of formed elements of blood
11.
Lymphocytes secrete antibodies, coordinate action of other immune cells, and serve in immune
memory.
TRUE
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Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K03.03c With respect to the functional roles of formed elements, describe functions for each of the five major types of
leukocytes as well as the two major subtypes of lymphocytes (T and B).
18-!3
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12.
Monocytes differentiate into large phagocytic cells.
TRUE
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Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K03.03c With respect to the functional roles of formed elements, describe functions for each of the five major types of
leukocytes as well as the two major subtypes of lymphocytes (T and B).
HAPS Topic: Module K03 Identity, microscopic anatomy, numbers, formation, and functional roles of the formed elements of blood.
Learning Outcome: 18.04a Explain the function of leukocytes in general and the individual role of each leukocyte type.
Section: 18.04
Topic: Functional roles of formed elements of blood
Topic: Microscopic anatomy of formed elements of blood
13.
Coagulation starts with a vascular spasm and ends with the formation of a platelet plug.
FALSE
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Blooms Level: 2. Understand
Gradable: automatic
HAPS Objective: K04.01 Distinguish between the terms hemostasis and coagulation.
HAPS Topic: Module K04 Hemostasis, including coagulation of blood.
Learning Outcome: 18.05a Describe the bodys mechanisms for controlling bleeding.
Section: 18.05
Topic: Hemostasis, including coagulation of blood
14.
Clotting deficiency can result from thrombocytopenia or hemophilia.
TRUE
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Blooms Level: 2. Understand
Gradable: automatic
HAPS Objective: K04.02c Describe the basic steps involved in the formation of the insoluble fibrin clot of hemostasis.
HAPS Topic: Module K04 Hemostasis, including coagulation of blood.
Learning Outcome: 18.05f Describe some disorders of blood clotting.
Section: 18.05
Topic: Clinical applications of the cardiovascular system
Topic: Hemostasis, including coagulation of blood
15.
After a wound is sealed, tissue repair is followed by fibrinolysis.
TRUE
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Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K04.05 Discuss the process of fibrinolysis, including the roles of plasminogen, tissue plasminogen activator and
plasmin.
HAPS Topic: Module K04 Hemostasis, including coagulation of blood.
Learning Outcome: 18.05d Explain what happens to blood clots when they are no longer needed.
Section: 18.05
18-!4
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Multiple Choice Questions
16.
Which of the following is not a function of blood?
A.
B.
C.
D.
E.
Transports a variety of nutrients
Helps to stabilize the pH of extracellular fluids
Participates in the initiation of blood clotting
Produces plasma hormones
Helps to regulate body temperature
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Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K01.01 Describe the major functions of the cardiovascular system.
HAPS Topic: Module K01 General functions of the cardiovascular system.
Learning Outcome: 18.01a Describe the functions and major components of the circulatory system.
Section: 18.01
Topic: General functions of the cardiovascular system
17.
Which of the following is not contained in the buffy coat?
A.
B.
C.
D.
E.
Lymphocytes
Granulocytes
Erythrocytes
Agranulocytes
Platelets
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Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K03.01c With respect to the structure and numbers of formed elements in blood, state the normal ranges for erythrocyte
counts and hematocrit (both male and female), total leukocyte count, and platelet count.
HAPS Topic: Module K03 Identity, microscopic anatomy, numbers, formation, and functional roles of the formed elements of blood.
Learning Outcome: 18.01b Describe the components and physical properties of blood.
Section: 18.01
Topic: Microscopic anatomy of formed elements of blood
18.
A normal hematocrit is __________ of the total blood volume.
A.
B.
less than 1%
47% to 63%
18-!5
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Accessibility: Keyboard Navigation
Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K03.01c With respect to the structure and numbers of formed elements in blood, state the normal ranges for erythrocyte
counts and hematocrit (both male and female), total leukocyte count, and platelet count.
HAPS Topic: Module K03 Identity, microscopic anatomy, numbers, formation, and functional roles of the formed elements of blood.
Learning Outcome: 18.01b Describe the components and physical properties of blood.
Section: 18.01
Topic: Microscopic anatomy of formed elements of blood
19.
Which of the following is not normally found in plasma?
A.
B.
C.
D.
E.
Glycogen
Fibrinogen
Glucose
Urea
Albumin
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Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K02.01 Describe the overall composition of plasma, including the major types of plasma proteins, their functions and
where in the body they are produced.
HAPS Topic: Module K02 Composition of blood plasma.
Learning Outcome: 18.01c Describe the composition of blood plasma.
Section: 18.01
Topic: Composition of blood plasma
20.
Which of the following proteins is not normally found in plasma?
A.
B.
C.
D.
E.
Albumin
Hemoglobin
Transferrin
Prothrombin
Fibrinogen
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Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K02.01 Describe the overall composition of plasma, including the major types of plasma proteins, their functions and
where in the body they are produced.
HAPS Topic: Module K02 Composition of blood plasma.
Learning Outcome: 18.01c Describe the composition of blood plasma.
Section: 18.01
Topic: Composition of blood plasma
21.
What is the most abundant protein in plasma?
18-!6
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Accessibility: Keyboard Navigation
Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K02.01 Describe the overall composition of plasma, including the major types of plasma proteins, their functions and
where in the body they are produced.
HAPS Topic: Module K02 Composition of blood plasma.
Learning Outcome: 18.01c Describe the composition of blood plasma.
Section: 18.01
Topic: Composition of blood plasma
22.
Which of the following would not decrease the blood colloid osmotic pressure (COP)?
A.
B.
C.
D.
E.
Severe liver failure
A diet predominantly based on red meat
Starvation
An extremely low-protein diet
Hypoproteinemia
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Blooms Level: 5. Evaluate
Gradable: automatic
HAPS Objective: K02.01 Describe the overall composition of plasma, including the major types of plasma proteins, their functions and
where in the body they are produced.
HAPS Topic: Module K02 Composition of blood plasma.
Learning Outcome: 18.01d Explain the significance of blood viscosity and osmolarity.
Section: 18.01
Topic: Composition of blood plasma
23.
Serum is essentially identical to plasma except for the absence of __________.
A.
B.
C.
D.
E.
fibrinogen
nitrogenous wastes
platelets
glucose
albumin
Accessibility: Keyboard Navigation
Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K02.01 Describe the overall composition of plasma, including the major types of plasma proteins, their functions and
where in the body they are produced.
HAPS Topic: Module K02 Composition of blood plasma.
Learning Outcome: 18.01c Describe the composition of blood plasma.
Section: 18.01
Topic: Composition of blood plasma
24.
Tissues can become edematous (swollen) when which of the following occurs?
18-!7
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McGraw-Hill Education.
Accessibility: Keyboard Navigation
Blooms Level: 5. Evaluate
Gradable: automatic
HAPS Objective: K02.01 Describe the overall composition of plasma, including the major types of plasma proteins, their functions and
where in the body they are produced.
HAPS Topic: Module K02 Composition of blood plasma.
Learning Outcome: 18.01d Explain the significance of blood viscosity and osmolarity.
Section: 18.01
Topic: Composition of blood plasma
25.
Where does myeloid hemopoiesis take place in adults?
A.
B.
C.
D.
E.
Thymus
Spleen
Red bone marrow
Yellow bone marrow
Liver
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Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K03.02a With respect to development of formed elements, describe the location of hematopoiesis and the significance of
the pluripotent stem cell (hemocytoblast).
HAPS Topic: Module K03 Identity, microscopic anatomy, numbers, formation, and functional roles of the formed elements of blood.
Learning Outcome: 18.01e Describe in general terms how blood is produced.
Learning Outcome: 18.04c Describe the formation and life history of leukocytes.
Section: 18.01
Section: 18.04
Topic: Functional roles of formed elements of blood
Topic: Microscopic anatomy of formed elements of blood
26.
The viscosity of blood is due more to the presence of __________ than to any other factor.
A.
B.
C.
D.
E.
fibrin
albumin
sodium
erythrocytes
nitrogenous wastes
Accessibility: Keyboard Navigation
Blooms Level: 2. Understand
Gradable: automatic
HAPS Objective: K03.03a With respect to the functional roles of formed elements, state the function of red blood cells.
HAPS Topic: Module K03 Identity, microscopic anatomy, numbers, formation, and functional roles of the formed elements of blood.
Learning Outcome: 18.01d Explain the significance of blood viscosity and osmolarity.
Section: 18.01
Topic: Composition of blood plasma
18-!8
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McGraw-Hill Education.
27.
Erythrocytes transport oxygen and __________.
A.
B.
C.
D.
E.
defend the body against pathogens
initiate blood clotting
regulate erythropoiesis
transport nutrients
transport some carbon dioxide
Accessibility: Keyboard Navigation
Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K03.03a With respect to the functional roles of formed elements, state the function of red blood cells.
HAPS Topic: Module K03 Identity, microscopic anatomy, numbers, formation, and functional roles of the formed elements of blood.
Learning Outcome: 18.02a Discuss the structure and function of erythrocytes (RBCs).
Section: 18.02
Topic: Functional roles of formed elements of blood
28.
Most oxygen is transported in the blood bound to __________.
A.
B.
C.
D.
E.
the plasma membrane of erythrocytes
alpha chains in hemoglobin
beta chains in hemoglobin
delta chains in hemoglobin
heme groups in hemoglobin
Accessibility: Keyboard Navigation
Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K03.03b With respect to the functional roles of formed elements, discuss the structure and function of hemoglobin, as
well as its breakdown products.
HAPS Topic: Module K03 Identity, microscopic anatomy, numbers, formation, and functional roles of the formed elements of blood.
Learning Outcome: 18.02b Describe the structure and function of hemoglobin.
Section: 18.02
Topic: Functional roles of formed elements of blood
29.
What would happen if all of the hemoglobin contained within the RBCs became free in the plasma?
A.
B.
C.
D.
E.
It would considerably increase blood oxygen carrying capacity.
It would facilitate delivery of oxygen into tissues supplied by small capillaries.
It would facilitate oxygen diffusion into cells distant from blood capillaries.
It would significantly increase blood osmolarity.
It would drastically increase osmotic colloid pressure.
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18-!9
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30.
An increased erythropoietin (EPO) output by the kidneys would lead to all of the following except
__________.
A.
B.
C.
D.
E.
increased hypoxemia
increased blood osmolarity
increased RBC production
increased blood viscosity
increased hematocrit
Accessibility: Keyboard Navigation
Blooms Level: 3. Apply
Gradable: automatic
HAPS Objective: K03.02b With respect to development of formed elements, explain the basic process of erythropoiesis, the significance of
the reticulocyte, and regulation through erythropoietin.
HAPS Topic: Module K03 Identity, microscopic anatomy, numbers, formation, and functional roles of the formed elements of blood.
Learning Outcome: 18.02d Describe the cycle of erythrocytes.
Section: 18.02
Topic: Functional roles of formed elements of blood
31.
Where do most RBCs die?
A.
B.
C.
D.
E.
Stomach and small intestine
Red bone marrow
Spleen and liver
Lymph nodes and thymus
Stomach and liver
Accessibility: Keyboard Navigation
Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K03.03b With respect to the functional roles of formed elements, discuss the structure and function of hemoglobin, as
well as its breakdown products.
HAPS Topic: Module K03 Identity, microscopic anatomy, numbers, formation, and functional roles of the formed elements of blood.
Learning Outcome: 18.02d Describe the cycle of erythrocytes.
Section: 18.02
Topic: Functional roles of formed elements of blood
Topic: Microscopic anatomy of formed elements of blood
32.
Which of the following would not lead to polycythemia?
A.
B.
C.
D.
E.
Cancer of the erythropoietic line of the red bone marrow
Iron deficiency
Dehydration
Emphysema
Excessive aerobic exercise
18-!10
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Accessibility: Keyboard Navigation
Blooms Level: 3. Apply
Gradable: automatic
HAPS Objective: K16.01 Predict factors or situations affecting the cardiovascular system that could disrupt homeostasis.
HAPS Topic: Module K16 Predictions related to homeostatic imbalance, including disease states and disorders.
Learning Outcome: 18.02e Name and describe the types, causes, and effects of RBC excesses and deficiencies.
Section: 18.02
Topic: Clinical applications of the cardiovascular system
Topic: Microscopic anatomy of formed elements of blood
33.
Which of the following is most likely to cause anemia?
A.
B.
C.
D.
E.
High altitude
Air pollution other than by carbon monoxide
Renal disease
Smoking
Any factor that creates a state of hypoxemia
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Blooms Level: 3. Apply
Gradable: automatic
HAPS Objective: K16.02 Predict the types of problems that would occur in the body if the cardiovascular system could not maintain
homeostasis.
HAPS Topic: Module K16 Predictions related to homeostatic imbalance, including disease states and disorders.
Learning Outcome: 18.02e Name and describe the types, causes, and effects of RBC excesses and deficiencies.
Section: 18.02
Topic: Clinical applications of the cardiovascular system
Topic: Microscopic anatomy of formed elements of blood
34.
Which of the following is not true of a patient with anemia?
A.
B.
C.
D.
E.
Their blood viscosity is increased.
They are lethargic.
Their blood osmolarity is reduced.
Their resistance to blood flow is reduced.
More fluid transfers from their bloodstream into their intercellular spaces.
Accessibility: Keyboard Navigation
Blooms Level: 3. Apply
Gradable: automatic
HAPS Objective: K03.03a With respect to the functional roles of formed elements, state the function of red blood cells.
HAPS Topic: Module K03 Identity, microscopic anatomy, numbers, formation, and functional roles of the formed elements of blood.
Learning Outcome: 18.02e Name and describe the types, causes, and effects of RBC excesses and deficiencies.
Section: 18.02
Topic: Clinical applications of the cardiovascular system
Topic: Functional roles of formed elements of blood
Topic: Microscopic anatomy of formed elements of blood
18-!11
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35.
What is the final product of the breakdown of the organic nonprotein moiety of hemoglobin?
A.
B.
C.
D.
E.
Biliverdin
Bilirubin
Globin
Heme
Iron
Accessibility: Keyboard Navigation
Blooms Level: 3. Apply
Gradable: automatic
HAPS Objective: K03.03b With respect to the functional roles of formed elements, discuss the structure and function of hemoglobin, as
well as its breakdown products.
HAPS Topic: Module K03 Identity, microscopic anatomy, numbers, formation, and functional roles of the formed elements of blood.
Learning Outcome: 18.02d Describe the cycle of erythrocytes.
Section: 18.02
Topic: Microscopic anatomy of formed elements of blood
36.
Correction of hypoxemia is regulated by __________.
A.
B.
C.
D.
E.
a self-amplifying mechanism
an enzymatic amplification
a positive feedback loop
a negative feedback loop
a cascade effect
Accessibility: Keyboard Navigation
Blooms Level: 3. Apply
Gradable: automatic
HAPS Objective: K03.02b With respect to development of formed elements, explain the basic process of erythropoiesis, the significance of
the reticulocyte, and regulation through erythropoietin.
HAPS Topic: Module K03 Identity, microscopic anatomy, numbers, formation, and functional roles of the formed elements of blood.
Learning Outcome: 18.02d Describe the cycle of erythrocytes.
Section: 18.02
Topic: Functional roles of formed elements of blood
37.
A deficiency of __________ can cause pernicious anemia.
A.
B.
C.
D.
E.
vitamin C
iron
vitamin B
EPO secretion
folic acid
18-!12
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Accessibility: Keyboard Navigation
Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K16.01 Predict factors or situations affecting the cardiovascular system that could disrupt homeostasis.
HAPS Topic: Module K16 Predictions related to homeostatic imbalance, including disease states and disorders.
Learning Outcome: 18.02e Name and describe the types, causes, and effects of RBC excesses and deficiencies.
Section: 18.02
Topic: Clinical applications of the cardiovascular system
Topic: Functional roles of formed elements of blood
38.
Which of the following is not true regarding sickle-cell disease?
A.
B.
C.
D.
E.
It is caused by a recessive allele that modifies the structure of hemoglobin.
It is due to a hereditary hemoglobin defect.
It is advantageous in that it can protect carriers against malaria.
It is a cause of malaria.
It is a cause of anemia.
Accessibility: Keyboard Navigation
Blooms Level: 2. Understand
Gradable: automatic
HAPS Objective: K16.01 Predict factors or situations affecting the cardiovascular system that could disrupt homeostasis.
HAPS Topic: Module K16 Predictions related to homeostatic imbalance, including disease states and disorders.
Learning Outcome: 18.02e Name and describe the types, causes, and effects of RBC excesses and deficiencies.
Section: 18.02
Topic: Clinical applications of the cardiovascular system
Topic: Functional roles of formed elements of blood
39.
The ABO blood group is determined by __________ in the plasma membrane of RBCs.
A.
B.
C.
D.
E.
glycolipids
glycoproteins
antibodies
antigen-antibody complexes
agglutinins
Accessibility: Keyboard Navigation
Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K05.01 Explain the role of surface antigens on RBCs in determining blood groups.
HAPS Topic: Module K05 ABO and Rh blood grouping.
Learning Outcome: 18.03a Explain what determines a persons ABO and Rh blood types and how this relates to transfusion compatibility.
Section: 18.03
Topic: ABO and Rh blood grouping
40.
A person with type A blood can safely donate RBCs to someone of type __________ and can receive
RBCs from someone of type __________.
18-!13
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Accessibility: Keyboard Navigation
Blooms Level: 3. Apply
Gradable: automatic
HAPS Objective: K05.05 Predict which blood types are compatible and what happens when the incorrect ABO or Rh blood type is
transfused.
HAPS Topic: Module K05 ABO and Rh blood grouping.
Learning Outcome: 18.03a Explain what determines a persons ABO and Rh blood types and how this relates to transfusion compatibility.
Section: 18.03
Topic: ABO and Rh blood grouping
41.
A person with type AB blood has __________ RBC antigen(s).
A.
B.
C.
D.
E.
no
anti-A and anti-B
anti-A
anti-B
A and B
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Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K05.02 List the type of antigen and the type of antibodies present in each ABO blood type.
HAPS Topic: Module K05 ABO and Rh blood grouping.
Learning Outcome: 18.03a Explain what determines a persons ABO and Rh blood types and how this relates to transfusion compatibility.
Section: 18.03
Topic: ABO and Rh blood grouping
42.
Why are pregnant Rh
A.
Antibodies in the injection bind fetal RBC antigens so they cannot stimulate her immune
system to produce anti-D antibodies.
B.
Antibodies in the injection bind fetal RBC antigens so they cannot stimulate her immune
system to produce anti-A and anti-B antibodies.
C.
Antibodies in the injection bind fetal RBC antigens so they cannot stimulate her immune
system to produce anti-A antibodies.
D.
Antibodies in the injection bind fetal RBC antigens so they cannot stimulate her immune
system to produce anti-O antibodies.
E.
Antibodies in the injection bind fetal RBC antigens so they cannot stimulate her immune
system to produce anti-B antibodies.
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Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K05.04 Distinguish between the development of anti-Rh antibodies and the development of anti-A and anti- B
antibodies.
HAPS Topic: Module K05 ABO and Rh blood grouping.
Learning Outcome: 18.03c Describe the effect of a blood type incompatibility between mother and fetus.
Section: 18.03
18-!14
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43.
The universal donor of RBCs, but not necessarily plasma, is blood type __________.
A.
B.
C.
D.
E.
AB, Rh-negative
AB, Rh-positive
O, Rh-negative
O, Rh-positive
ABO, Rh-negative
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Blooms Level: 2. Understand
Gradable: automatic
HAPS Objective: K05.06 State which blood type is considered the universal donor and which blood type is considered the universal
recipient, and explain why.
HAPS Topic: Module K05 ABO and Rh blood grouping.
Learning Outcome: 18.03a Explain what determines a persons ABO and Rh blood types and how this relates to transfusion compatibility.
Section: 18.03
Topic: ABO and Rh blood grouping
44.
An individual has type B, Rh-positive blood. The individual has __________ antigen(s) and can
produce anti-__________ antibodies.
A.
B.
C.
D.
E.
A and D; B
B and D; A
B; A and D
A; B and D
D; A and B
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Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K05.02 List the type of antigen and the type of antibodies present in each ABO blood type.
HAPS Objective: K05.03 Describe how the presence or absence of Rh antigen results in blood being classified as positive or negative.
HAPS Topic: Module K05 ABO and Rh blood grouping.
Learning Outcome: 18.03a Explain what determines a persons ABO and Rh blood types and how this relates to transfusion compatibility.
Section: 18.03
Topic: ABO and Rh blood grouping
45.
The main reason why an individual with type AB, Rh-negative blood cannot donate blood to an
individual with type A, Rh-positive blood is because __________.
A.
B.
C.
D.
E.
anti-A antibodies in the donor will agglutinate RBCs of the recipient
anti-A antibodies in the recipient will agglutinate RBCs of the donor
anti-B antibodies in the donor will agglutinate RBCs of the recipient
anti-D antibodies in the donor will agglutinate RBC of the recipient
anti-B antibodies in the recipient will agglutinate RBCs of the donor
18-!15
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Blooms Level: 5. Evaluate
Gradable: automatic
HAPS Objective: K05.05 Predict which blood types are compatible and what happens when the incorrect ABO or Rh blood type is
transfused.
HAPS Topic: Module K05 ABO and Rh blood grouping.
Learning Outcome: 18.03a Explain what determines a persons ABO and Rh blood types and how this relates to transfusion compatibility.
Section: 18.03
Topic: ABO and Rh blood grouping
46.
A woman's first pregnancy is normal but her second pregnancy results in hemolytic disease of the
newborn (HDN). The second child needed a transfusion to completely replace the agglutinating blood.
The mother is most likely type __________ and both children are most likely __________.
A.
B.
C.
D.
E.
A, Rh-negative; B, Rh-positive
A, Rh-positive; B, Rh-negative
O, Rh-negative; AB, Rh-negative
AB, Rh-positive; O, Rh-negative
AB, Rh-positive; O, Rh-positive
Accessibility: Keyboard Navigation
Blooms Level: 5. Evaluate
Gradable: automatic
HAPS Objective: K05.05 Predict which blood types are compatible and what happens when the incorrect ABO or Rh blood type is
transfused.
HAPS Topic: Module K05 ABO and Rh blood grouping.
Learning Outcome: 18.03c Describe the effect of a blood type incompatibility between mother and fetus.
Section: 18.03
Topic: ABO and Rh blood grouping
47.
What are the least abundant of the formed elements?
A.
B.
C.
D.
E.
Platelets
Basophils
Erythrocytes
Neutrophils
Eosinophils
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Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K03.01c With respect to the structure and numbers of formed elements in blood, state the normal ranges for erythrocyte
counts and hematocrit (both male and female), total leukocyte count, and platelet count.
HAPS Topic: Module K03 Identity, microscopic anatomy, numbers, formation, and functional roles of the formed elements of blood.
Learning Outcome: 18.04b Describe the appearance and relative abundance of each type of leukocyte.
Section: 18.04
Topic: Microscopic anatomy of formed elements of blood
18-!16
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48.
What are the most abundant agranulocytes?
A.
B.
C.
D.
E.
Macrophages
Eosinophils
Monocytes
Lymphocytes
Neutrophils
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Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K03.01c With respect to the structure and numbers of formed elements in blood, state the normal ranges for erythrocyte
counts and hematocrit (both male and female), total leukocyte count, and platelet count.
HAPS Topic: Module K03 Identity, microscopic anatomy, numbers, formation, and functional roles of the formed elements of blood.
Learning Outcome: 18.04b Describe the appearance and relative abundance of each type of leukocyte.
Section: 18.04
Topic: Microscopic anatomy of formed elements of blood
49.
The number of __________ typically increases in response to bacterial infections.
A.
B.
C.
D.
E.
basophils
monocytes
erythrocytes
eosinophils
neutrophils
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Blooms Level: 3. Apply
Gradable: automatic
HAPS Objective: K03.03c With respect to the functional roles of formed elements, describe functions for each of the five major types of
leukocytes as well as the two major subtypes of lymphocytes (T and B).
HAPS Topic: Module K03 Identity, microscopic anatomy, numbers, formation, and functional roles of the formed elements of blood.
Learning Outcome: 18.04b Describe the appearance and relative abundance of each type of leukocyte.
Section: 18.04
Topic: Functional roles of formed elements of blood
Topic: Microscopic anatomy of formed elements of blood
50.
Which cells aid in the body's defense processes by secreting histamine and heparin?
A.
B.
C.
D.
E.
Eosinophils
Basophils
Neutrophils
Platelets
Monocytes
18-!17
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Accessibility: Keyboard Navigation
Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K03.03c With respect to the functional roles of formed elements, describe functions for each of the five major types of
leukocytes as well as the two major subtypes of lymphocytes (T and B).
HAPS Topic: Module K03 Identity, microscopic anatomy, numbers, formation, and functional roles of the formed elements of blood.
Learning Outcome: 18.04a Explain the function of leukocytes in general and the individual role of each leukocyte type.
Section: 18.04
Topic: Functional roles of formed elements of blood
51.
Leukopoiesis begins with the differentiation of __________.
A.
B.
C.
D.
E.
pluripotent stem cells
precursor cells
colony-forming units
myeloblasts
lymphoblasts
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Blooms Level: 2. Understand
Gradable: automatic
HAPS Objective: K03.02a With respect to development of formed elements, describe the location of hematopoiesis and the significance of
the pluripotent stem cell (hemocytoblast).
HAPS Topic: Module K03 Identity, microscopic anatomy, numbers, formation, and functional roles of the formed elements of blood.
Learning Outcome: 18.04c Describe the formation and life history of leukocytes.
Section: 18.04
Topic: Functional roles of formed elements of blood
Topic: Microscopic anatomy of formed elements of blood
52.
Some lymphocytes can survive as long as __________.
A.
B.
C.
D.
E.
days
weeks
months
years
decades
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Blooms Level: 2. Understand
Gradable: automatic
HAPS Objective: K03.01d With respect to the structure and numbers of formed elements in blood, list the five types of leukocytes in order
of their relative prevalence in normal blood and classify each type as granulocyte or agranulocyte.
HAPS Topic: Module K03 Identity, microscopic anatomy, numbers, formation, and functional roles of the formed elements of blood.
Learning Outcome: 18.04c Describe the formation and life history of leukocytes.
Section: 18.04
Topic: Functional roles of formed elements of blood
Topic: Microscopic anatomy of formed elements of blood
18-!18
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53.
A patient is diagnosed with leukocytosis if they have more than __________ WBCs/μL.
A.
B.
C.
D.
E.
100,000
50,000
10,000
5,000
1,000
Accessibility: Keyboard Navigation
Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K16.01 Predict factors or situations affecting the cardiovascular system that could disrupt homeostasis.
HAPS Topic: Module K16 Predictions related to homeostatic imbalance, including disease states and disorders.
Learning Outcome: 18.04d Discuss the types, causes, and effects of leukocyte excesses and deficiencies.
Section: 18.04
Topic: Clinical applications of the cardiovascular system
Topic: Functional roles of formed elements of blood
54.
Which of the following has not been implicated in causing leukopenia?
A.
B.
C.
D.
E.
Acquired Immunodeficiency Syndrome (AIDS)
Lead poisoning
Radiation therapy
Dehydration
Immunosuppressant drugs
Accessibility: Keyboard Navigation
Blooms Level: 3. Apply
Gradable: automatic
HAPS Objective: K16.01 Predict factors or situations affecting the cardiovascular system that could disrupt homeostasis.
HAPS Topic: Module K16 Predictions related to homeostatic imbalance, including disease states and disorders.
Learning Outcome: 18.04d Discuss the types, causes, and effects of leukocyte excesses and deficiencies.
Section: 18.04
Topic: Clinical applications of the cardiovascular system
Topic: Functional roles of formed elements of blood
55.
What is the largest leukocyte that contains small cytoplasmic granules and typically a kidney- or
horseshoe-shaped nucleus?
A.
B.
C.
D.
E.
Monocyte
Lymphocyte
Neutrophil
Eosinophil
Basophil
18-!19
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Accessibility: Keyboard Navigation
Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K03.01a With respect to the structure and numbers of formed elements in blood, identify microscopically erythrocytes
(red blood cells or RBCs), the five types of leukocytes (white blood cells or WBCs) and thrombocytes (platelets).
HAPS Topic: Module K03 Identity, microscopic anatomy, numbers, formation, and functional roles of the formed elements of blood.
Learning Outcome: 18.04b Describe the appearance and relative abundance of each type of leukocyte.
Section: 18.04
Topic: Microscopic anatomy of formed elements of blood
56.
Which of the following are not secreted by platelets?
A.
B.
C.
D.
E.
Procoagulants
Thrombopoietin
Growth factors
Vasoconstrictors
Chemicals that attract neutrophils
Accessibility: Keyboard Navigation
Blooms Level: 2. Understand
Gradable: automatic
HAPS Objective: K04.02b Describe the role of platelets and the steps involved in the formation of the platelet plug of hemostasis.
HAPS Topic: Module K04 Hemostasis, including coagulation of blood.
Learning Outcome: 18.05b List the functions of platelets.
Section: 18.05
Topic: Microscopic anatomy of formed elements of blood
57.
The cessation of bleeding is specifically called __________.
A.
B.
C.
D.
E.
a vascular spasm
homeostasis
hemostasis
platelet plug formation
coagulation
Accessibility: Keyboard Navigation
Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K04.01 Distinguish between the terms hemostasis and coagulation.
HAPS Topic: Module K04 Hemostasis, including coagulation of blood.
Learning Outcome: 18.05a Describe the bodys mechanisms for controlling bleeding.
Section: 18.05
Topic: Hemostasis, including coagulation of blood
58.
What is the function of thromboplastin in hemostasis?
18-!20
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Accessibility: Keyboard Navigation
Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K04.02d Differentiate between the intrinsic and extrinsic clotting mechanisms of hemostasis.
HAPS Topic: Module K04 Hemostasis, including coagulation of blood.
Learning Outcome: 18.05c Describe two reaction pathways that produce blood clots.
Section: 18.05
Topic: Hemostasis, including coagulation of blood
59.
When a clot is no longer needed, fibrin is dissolved by __________.
A.
B.
C.
D.
E.
prothrombin
thromboplastin
kallikrein
plasmin
platelet-derived growth factor
Accessibility: Keyboard Navigation
Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K04.05 Discuss the process of fibrinolysis, including the roles of plasminogen, tissue plasminogen activator and
plasmin.
HAPS Topic: Module K04 Hemostasis, including coagulation of blood.
Learning Outcome: 18.05d Explain what happens to blood clots when they are no longer needed.
Section: 18.05
Topic: Hemostasis, including coagulation of blood
60.
Which of these does not prevent the spontaneous formation of a clot?
A.
B.
C.
D.
E.
The presence of tissue thromboplastin
The smooth prostacyclin-coated endothelium of blood vessels
The dilution of thrombin when blood flows at a normal rate
The presence of antithrombin in plasma
The presence of heparin in plasma
Accessibility: Keyboard Navigation
Blooms Level: 2. Understand
Gradable: automatic
HAPS Objective: K04.06 Explain the mechanisms of action and give examples of procoagulants, anticoagulants and fibrinolytic drugs.
HAPS Topic: Module K04 Hemostasis, including coagulation of blood.
Learning Outcome: 18.05e Explain what keeps blood from clotting in the absence of injury.
Section: 18.05
Topic: Hemostasis, including coagulation of blood
61.
Platelets release __________, a chemical vasoconstrictor that contributes to the vascular spasm.
18-!21
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Accessibility: Keyboard Navigation
Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K04.02b Describe the role of platelets and the steps involved in the formation of the platelet plug of hemostasis.
HAPS Topic: Module K04 Hemostasis, including coagulation of blood.
Learning Outcome: 18.05b List the functions of platelets.
Section: 18.05
Topic: Hemostasis, including coagulation of blood
62.
The structural framework of a blood clot is formed by __________.
A.
B.
C.
D.
E.
soluble fibrinogen
soluble fibrin
a fibrin polymer
a fibrinogen polymer
a thrombin polymer
Accessibility: Keyboard Navigation
Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K04.02c Describe the basic steps involved in the formation of the insoluble fibrin clot of hemostasis.
HAPS Topic: Module K04 Hemostasis, including coagulation of blood.
Learning Outcome: 18.05a Describe the bodys mechanisms for controlling bleeding.
Section: 18.05
Topic: Hemostasis, including coagulation of blood
63.
Most strokes and heart attacks are caused by the abnormal clotting of blood in an unbroken vessel.
Moreover, a piece of the __________ (clot) may break loose and begin to travel in the bloodstream as
a(n) __________.
A.
B.
C.
D.
E.
thrombus; embolus
embolism; thrombus
plaque; thrombus
thrombosis; plaque
plaque; embolus
Accessibility: Keyboard Navigation
Blooms Level: 3. Apply
Gradable: automatic
HAPS Objective: K16.01 Predict factors or situations affecting the cardiovascular system that could disrupt homeostasis.
HAPS Topic: Module K16 Predictions related to homeostatic imbalance, including disease states and disorders.
Learning Outcome: 18.05f Describe some disorders of blood clotting.
Section: 18.05
Topic: Hemostasis, including coagulation of blood
64.
During coagulation, which of the following is found in the extrinsic mechanism only?
18-!22
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Accessibility: Keyboard Navigation
Blooms Level: 2. Understand
Gradable: automatic
HAPS Objective: K04.02d Differentiate between the intrinsic and extrinsic clotting mechanisms of hemostasis.
HAPS Topic: Module K04 Hemostasis, including coagulation of blood.
Learning Outcome: 18.05c Describe two reaction pathways that produce blood clots.
Section: 18.05
Topic: Hemostasis, including coagulation of blood
65.
Where are most clotting factors synthesized in the body?
A.
B.
C.
D.
E.
Spleen
Red bone marrow
Perivascular tissue
Kidneys
Liver
Accessibility: Keyboard Navigation
Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K04.02d Differentiate between the intrinsic and extrinsic clotting mechanisms of hemostasis.
HAPS Topic: Module K04 Hemostasis, including coagulation of blood.
Learning Outcome: 18.05c Describe two reaction pathways that produce blood clots.
Section: 18.05
Topic: Hemostasis, including coagulation of blood
66.
A patient is suffering from ketoacidosis caused by an unregulated high protein diet. Which function
of the blood has been compromised?
A.
B.
C.
D.
E.
Stabilizing fluid distribution in the body
Stabilizing the body's pH
Protecting against microorganisms
Transporting nutrients
Transporting hormones
Accessibility: Keyboard Navigation
Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K01.01 Describe the major functions of the cardiovascular system.
HAPS Topic: Module K01 General functions of the cardiovascular system.
Learning Outcome: 18.01a Describe the functions and major components of the circulatory system.
Section: 18.01
Topic: Clinical applications of the cardiovascular system
Topic: Functional roles of formed elements of blood
67.
Where in the body are hemopoietic stem cells found?
18-!23
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Accessibility: Keyboard Navigation
Blooms Level: 2. Understand
Gradable: automatic
HAPS Objective: K03.02a With respect to development of formed elements, describe the location of hematopoiesis and the significance of
the pluripotent stem cell (hemocytoblast).
HAPS Topic: Module K03 Identity, microscopic anatomy, numbers, formation, and functional roles of the formed elements of blood.
Learning Outcome: 18.01e Describe in general terms how blood is produced.
Section: 18.01
Topic: Microscopic anatomy of formed elements of blood
68.
Which of the following might be injected into a patient who is prone to forming blood clots and
therefore at risk of a heart attack or stroke?
A.
B.
C.
D.
E.
Thromboplastin
Fibrinogen
Fibrin
Heparin
Factor X
Accessibility: Keyboard Navigation
Blooms Level: 2. Understand
Gradable: automatic
HAPS Objective: K04.06 Explain the mechanisms of action and give examples of procoagulants, anticoagulants and fibrinolytic drugs.
HAPS Topic: Module K04 Hemostasis, including coagulation of blood.
Learning Outcome: 18.05e Explain what keeps blood from clotting in the absence of injury.
Section: 18.05
Topic: Clinical applications of the cardiovascular system
Topic: Hemostasis, including coagulation of blood
69.
Blood clots in the limbs put a patient most at risk for __________.
A.
B.
C.
D.
E.
hemophilia
pulmonary embolism
thrombocytopenia
disseminated intravascular coagulation (DIC)
septicemia
Accessibility: Keyboard Navigation
Blooms Level: 2. Understand
Gradable: automatic
HAPS Objective: K16.02 Predict the types of problems that would occur in the body if the cardiovascular system could not maintain
homeostasis.
HAPS Topic: Module K16 Predictions related to homeostatic imbalance, including disease states and disorders.
Learning Outcome: 18.05f Describe some disorders of blood clotting.
Section: 18.05
Topic: Clinical applications of the cardiovascular system
Topic: Hemostasis, including coagulation of blood
18-!24
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True / False Questions
70.
Blood groups are made up of any surface antigen on formed elements, not just ABO and Rh, and
include over 500 known antigens.
TRUE
Accessibility: Keyboard Navigation
Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K05.01 Explain the role of surface antigens on RBCs in determining blood groups.
HAPS Topic: Module K05 ABO and Rh blood grouping.
Learning Outcome: 18.03b List some blood groups other than ABO and Rh and explain how the may be useful.
Section: 18.03
Topic: ABO and Rh blood grouping
71.
Blood groups are used for legal purposes and in anthropology.
TRUE
Accessibility: Keyboard Navigation
Blooms Level: 1. Remember
Gradable: automatic
HAPS Objective: K05.01 Explain the role of surface antigens on RBCs in determining blood groups.
HAPS Topic: Module K05 ABO and Rh blood grouping.
Learning Outcome: 18.03b List some blood groups other than ABO and Rh and explain how the may be useful.
Section: 18.03
Topic: ABO and Rh blood grouping
18-!25
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