Biology Sylvia S. Mader Michael Windelspecht Chapter 31 Animal Organization and Homeostasis Lecture Outline See separate FlexArt PowerPoint slides for all figures and tables pre-inserted into PowerPoint without notes. 1 Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. 31.1 Types of Tissue • Tissues are: Collections of specialized cells organized to perform a common function The four tissue types are: Epithelial Connective Muscular Nervous 3 Types of Tissue • Epithelial Tissue (epithelium) Forms a continuous layer over body surfaces Lines body cavities Forms glands Epithelial cells may be connected to one another by • Tight junctions • Adhesion junctions • Gap junctions 4 Functions of epithelial tissue include: Protection Secretion Absorption Excretion Filtration 5 3 types of epithelial tissue 1. Simple 2. Stratified 3. glandular 6 Types of Tissue • Simple Epithelia - A single layer of cells Classified according to cell type: • Squamous epithelium – flattened cells • Cuboidal epithelium – cube-shaped cells • Columnar epithelium – cells resembling columns Glandular Epithelia • - Secretes a product A gland can be a single epithelial cell or can contain many cells Exocrine glands - Secrete products into ducts or cavities Endocrine glands - Secrete products directly into the bloodstream 8 Stratified Epithelia – Layers of cells 9 Types of Epithelial Tissues in the Vertebrates Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Simple squamous • lining of lungs, blood vessels • allows diffusion Simple cuboidal • lining of kidney tubules, various glands • absorbs molecules basement membrane basement membrane (All): © Ed Reschke 10 Types of Epithelial Tissues in the Vertebrates Copyright © The McGraw-Hill Companies, Inc. 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Simple columnar • lining of small intestine, oviducts • absorbs nutrients Pseudostratified, ciliated columnar • lining of trachea • sweeps impurities toward throat Stratified squamous • lining of nose, mouth, esophagus, anal canal, vagina • protects cilia goblet cell secretes mucus goblet cell secretes mucus basement membrane basement membrane basement membrane (All): © Ed Reschke 11 • Connective tissue functions: Establishing a structural framework Transporting fluids and dissolved materials Protecting delicate organs Supporting, surrounding and interconnecting tissues Storing energy reserves Defending the body from microorganisms 12 • Connective tissue: Specialized cells Ground substance - Noncellular material Protein fibers • Collagen fibers - contain collagen providing strength and flexibility • Reticular fibers – contain thinly branched collagen fibers • Elastic fibers – contain elastin 13 Three categories of connective tissue Fibrous Supportive Fluid 14 Types of Connective Tissue in Vertebrates Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Loose fibrous connective tissue Adipose tissue Dense fibrous connective tissue • has space between components. • occurs beneath skin and most epithelial layers. • functions in support and binds organs. • cells are filled with fat. • occurs beneath skin, around heart and other organs. • functions in insulation, stores fat. • has collagenous fibers closely packed. • in dermis of skin, tendons, ligaments. • functions in support. fibroblast 50 µm elastic fiber a. 50 µm collagen fiber 400x collagen fibers nucleus b. nuclei of fibroblasts c. (a, b); (c): © The McGraw-Hill Companies,Inc. Dennis Strete, Photographer 15 Types of Connective Tissue in Vertebrates Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Hyaline cartilage Compact bone • has cells in concentric rings. • occurs in bones of skeleton. • functions in support and protection. central canal osteon • has cells in lacunae. • occurs in nose; in the walls of respiratory passages; at ends of bones, Including ribs. • functions in support and protection. chondrocyte within lacunae d. 50 µm osteocyte canaliculi within a lacuna matrix e. (d, e): © Ed Reschke 320x 16 Fibrous Connective Tissue consist of: • Fibroblast cells • A matrix containing collagen and elastic fibers Loose fibrous connective tissue • Allows organs to expand Adipose tissue • Stores energy • Insulates the body and provides padding Dense fibrous connective tissue • Strong connective tissue • Tendons – connect muscle to bone • Ligaments – connect bones to other bones at joints 17 Diagram of Fibrous Connective Tissue Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Adipose cell: stores fat Stem cell: divides to produce other types of cells Collagen fiber: unbranched, strong but flexible Ground substance: fills spaces between cells and fibers Elastic fiber: branched and stretchable Fibroblast: divides to produce other types of cells Reticular fiber: branched, thin, and forms network White blood cell: engulfs pathogens or produces antibodies Blood vessel 18 Supportive Connective Tissue Cartilage • Classified according to type of collagen and elastic fibers found in the matrix (hyaline cartilage, elastic cartilage, fibrocartilage) • Cartilage cells lie in small chambers (lacuna) in the matrix Bone • Matrix is inorganic salts deposited around protein fibers • Bone cells are located in lacunae • Lacunae arranged in concentric circles within osteons around tiny tubes (central canals) 19 Fluid Connective Tissues Blood • A connective tissue in which cells are embedded in a liquid matrix (plasma) – Red blood cells – oxygen transport – White blood cells – immune response – Platelets – involved in the clotting process • Functions – Transports nutrients and oxygen to cells – Removes carbon dioxide and other wastes Lymph • A fluid connective tissue located in lymphatic vessels 20 Blood, a Liquid Tissue Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. plasma white blood cells (leukocytes) red blood cells (erythrocytes) a. Blood sample after centrifugation white blood cell platelets red blood cell plasma b. Blood smear 21 Muscular (contractile) Tissue Contractile cells containing actin and myosin filaments Cells are called muscle fibers Three types of muscle tissue: • Skeletal Muscle – Voluntary - Long, striated fibers, multinucleated • Smooth (visceral) Muscle – Involuntary - No striations • Cardiac Muscle – Striated, but mostly involuntary – Cells are bound to each other by intercalated disks – Relies on pacemaker cells for regular contraction 22 Muscular Tissue Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Skeletal muscle • has striated cells with multiple nuclei. • occurs in muscles attached to skeleton. • functions in voluntary movement of body. striation Smooth muscle • has spindle-shaped cells, each with a single nucleus. • cells have no striations. • functions in movement of substances in lumens of body. • is involuntary. • is found in blood vessel walls and walls of the digestive tract. nucleus smooth muscle cell a. b. nucleus 400 Cardiac muscle • has branching, striated cells, each with a single nucleus. • occurs in the wall of the heart. • functions in the pumping of blood. • is involuntary. intercalated disk nucleus 250 c. a, c: © Ed Reschke; b: © McGraw-Hill Higher Education, Dennis Strete, photographer 23 Nervous system (functions): Sensory input • Sensory receptors detect changes • Transmit information to the spinal cord and brain Data integration • Spinal cord and brain integrate data • Decision is made regarding appropriate response Motor output • Response is transmitted to effector (gland or muscle) • Effector initiates the actual response 24 Nervous Tissue Conducts electrical impulses Conveys information from one area to another Nervous tissue includes: • Neurons – Transmit information – Consist of dendrites, a cell body, and an axon – Outside the brain and spinal cord, fibers bound by connective tissue form nerves. 25 Nervous Tissue Neuroglia • Support and nourish neurons • Neuroglia in brain include – Microglia – Astrocytes – Oligodentrocytes 26 Neurons and Neuroglia Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. dendrite Neuron nucleus cell body axon Microglia Astrocyte Oligodendrocyte myelin sheath axon b. Micrograph of a neuron Capillary a. Neuron and neuroglia 200× 27 b: © Ed Reschke Regenerative Medicine • In humans, axons outside the brain and spinal cord can regenerate, but not those inside these organs. • Injured neurons in CNS degenerate Permanent loss of nervous function. • In cold-water fishes and amphibians axon regeneration in the CNS does occur. Several proteins play role in axon regeneration 28 Creating a New Type of Salamander for Limb Regeneration 31.2 Organs, Organ Systems, and Body Cavities • Organ Composed of two or more tissue types working together for a particular function • Organ System Composed of various organs that cooperate to carry out a general process • Ex: the digestion of food 30 Body Cavities 1.Dorsal cavity (toward the back) • Contains the cranial cavity and the vertebral canal • The brain is in the cranial cavity, and • The spinal cord is in the vertebral canal 2. Ventral cavity (toward the front) is divided into • The thoracic cavity (includes heart and lungs), • The abdominal cavity (most other internal organs), and • The pelvic cavity (certain reproductive organs) 31 Mammalian Body Cavities Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Cranial cavity: contains brain Thoracic cavity: contains heart, lungs, and esophagus Ventral cavity diaphragm Abdominal cavity: contains stomach, liver , spleen, pancreas, and intestines Pelvic cavity: contains certain reproductive organs a. Vertebral cavity: contains spinal cord Dorsal cavity 32 Mammalian Body Cavities Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Thoracic cavity: contains esophagus, heart, and lungs Abdominal cavity: contains digestive and other organs Pelvic cavity: contains reproductive and other organs b. 33 31.3 The Integumentary System • Functions of skin Covers and protects underlying body regions Regulates body temperature, and Contains sensory receptors • Skin and its derivatives make up the integumentary system 34 Regions of the Skin Epidermis Dermis Subcutaneous Layer 35 - Outer, thinner region Stratified squamous epithelium New cells are pushed outward, become keratinized, and are sloughed off Melanocytes produce melanin (pigment) UV radiation can cause mutations in the DNA of skin cells, leading to skin cancer. 36 Dermis - Deeper and thicker than epidermis • Fibrous connective tissue containing elastic and collagen fibers contains: – Receptors – Nerve fibers – Blood vessels Subcutaneous Layer - Loose, connective tissue located below dermis 37 The Integumentary System • Accessory Structures of Human Skin: Nails Hair follicles Hair follicles 38 Nails Grow from nail root and form protective covering of distal portion of fingers and toes 39 Hair follicles Begin in the dermis and continue through the epidermis Contain oil glands (sebaceous glands) which secrete sebum Lubricates the hair within the follicle as well as the skin 40 Hair follicles Begin in the dermis and continue through the epidermis Contain oil glands (sebaceous glands) which secrete sebum Lubricates the hair within the follicle as well as the skin 41 Human Skin Anatomy Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. hair shaft sweat pore melanocytes Epidermis sensory receptor capillaries oil gland arrector pili muscle Dermis free nerve endings hair follicle hair root sweat gland artery vein Subcutaneous layer nerve adipose tissue 42 The Epidermis flattened and dead cells Epidermis Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. b. Basal cell carcinoma cells undergoing keratinization dermal projection a. Photomicrograph of skin Dermis stem cells and melanocytes c. Melanoma a: © John D. Cunningham/Visuals Unlimited; b: © Ken Greer/Visuals Unlimited; c: © James Stevenson/SPL/Photo Researchers, Inc. 43 31.4 Homeostasis • The organ systems of the human body contribute to homeostasis: The ability of an organism to maintain a relatively constant internal environment Animals vary to the degree in which they can regulate internal variables. 44 The organ systems of the human body contribute to homeostasis 1.The digestive system • Takes in and digests food • Provides nutrient molecules that replace used nutrients 2.The respiratory system • Adds oxygen to the blood • Removes carbon dioxide 3.The liver and the kidneys • Store excess glucose as glycogen • Later, glycogen is broken down to replace the glucose used • The hormone insulin regulates glycogen storage 4.The kidneys • Under hormonal control as they excrete wastes and salts 45 Homeostasis • Homeostatic Control Partially controlled by hormones Ultimately controlled by the nervous system 46 Negative feedback is the primary homeostatic mechanism that keeps a variable close to a set value • Sensor detects change in environment • Regulatory center initiates an action to bring the conditions back to normal 47 Regulation of Room Temperature Using Negative Feedback Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Control center sends data to thermostat 68°F set point directs furnace to turn off Sensor 70°F too hot furnace off negative feedback and return to normal temperature stimulus Homeostasis negative feedback and return to normal temperature stimulus Sensor furnace on 66°F too cold Control center directs furnace to turn on sends data to thermostat 68°F set point 48 Regulation of Body Temperature by Negative Feedback Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Control center sends data to control center directs response to stimulus 98.6°F set point Sensor Effect Blood vessels dilate; sweat glands secrete. negative feedback and return to normal temperature stimulus Normal body temperature negative feedback and return to normal stimulus Effect Blood vessels constrict; sweat glands are inactive. Sensor Control center directs response to stimulus sends data to control center 98.6°F set point Positive feedback • is a mechanism that brings about an ever greater change in the same direction Childbirth process • Positive Feedback Does not result in equilibrium Does not occur as often as negative feedback 50 Positive Feedback Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. 2. Signals cause pituitary gland to release the hormone oxytocin. As the level of oxytocin increases, so do uterine contractions until birth occurs. pituitary gland + + 1. Due to uterine contractions, baby’s head presses on cervix, and signals are sent to brain. uterus Animation Please note that due to differing operating systems, some animations will not appear until the presentation is viewed in Presentation Mode (Slide Show view). You may see blank slides in the “Normal” or “Slide Sorter” views. 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