Name:
Date:
Period:
DNA Replication
(in Eukaryotic Cells)
In order to complete this assignment, you are required to visit websites and view
youtube clips. For each website or video you view, you are required to take notes on
any of the key vocabulary listed below.
1st set of notes: The Structure of DNA
View the youtube clip entitled, “5’ and 3’ ends of DNA.mov” (video length is 4.19).
Key vocabulary from this video clip:
Nucleotide 5 carbon sugar
phosphate
Monomer
polymer
purines
nitrogen bases
pyrimidines
hydroxyl group
hydrogen bonds
Key Question: Why are DNA strands labeled as 5’ and 3’? Which is considered the
“top” and “bottom” on the left (leading) strand of DNA? On the right (lagging) strand of
DNA?
*Remember to take notes using the terms to answer the
questions. Attach your notes labeled, “5’ and 3’ DNA video,”
to this sheet.
2nd set of notes: How does DNA get replicated?
View 2 youtube clips: “DNA Replication: The Cell’s Extreme Team Sport” (7 min 59
sec., created by the Amoeba Sisters) AND one other DNA replication clip of your
choice (1-3 minutes in length).
Key vocabulary from this video clip:
Helicase
DNA polymerase III
RNA primer RNA primase
Okazaki Fragments
Continuous Replication
DNA polymerase I
Leading strand
5’ to 3’
DNA Ligase
Lagging strand
3’ to 5’
Key Question:
Why can’t DNA Polymerase I replicate (copy) both sides of DNA the same way? Why
are Okazaki Fragments formed on the lagging strand, but not the leading strand of
DNA? Ultimately, one strand gets copied backwards (leading or lagging)… WHY??
Attach your notes entitled, “DNA Replication video clips,” to this
sheet.
Name:
Date:
Period:
3rd set of notes: Biology Place BioCoach: DNA Structure & Replication
Go to pearson biocoach (PHSchool-the biology place) and click on DNA Structure and
Replication
http://www.phschool.com/science/biology_place/biocoach/dnarep/intro
For all of the concepts (listed in the blue margin on the left side of your screen), you
can read about the concept. For extra practice, click on the green practice or purple
review before continuing onto the next concept. TAKE NOTES AS YOU GO!!
Key questions from this site:
1) Why is the basic building block (monomer) of DNA a nucleotide? Name the 3
parts of the nucleotide and indicate which part are the 5’ and the 3’.
2) Why is the semi-conservative model of replication the correct model of DNA
replication? Who are the name of the scientists that discovered this mode of
replication?
3) Draw a 2 sided DNA molecule and label the 5’ and 3’ ends on both strands.
Why are these strands considered to be “anti-parallel?”
4) Why are the DNA antiparalllel strands a problem for DNA polymerase?
5) How has this “antiparallel” problem been solved as DNA is replicated?
ATTACH YOUR NOTES AND THE ANSWERS TO THESE 5 QUESTIONS.
COMPLETE THE QUIZ AT THE END OF THE BIOCOACH TUTORIAL.