Biochemistry AA Metabolism
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Across
Down
✓9. A metabolic condition characterized by
elevated levels of ammonia in the blood
✓1. A post-translational modification that
marks proteins for degradation.
✓13. Plays a special role in transporting
amino groups from the muscle to the liver
in a nontoxic form.
✓2. Removal of amino groups are removed
from amino acids, resulting in the formation
of corresponding keto acids and ammonia.
(2 words)
:
✓14. A mutation of this enzyme (due to
genetic defect) resulting in reduced melanin
production that leads to albinism.
✓15. An enzyme that catalyzes
transamination reaction between an amino
acid and an alpha-keto acid.
✓17. A rare metabolic condition
characterized by an excess of the
compound homocystine in the urine.
✓19. A precursor to fumarate and arginine
in the urea cycle via argininosuccinate
lyase.
✓20. An organic nitrogenous compound
produced as part of a local immune
response to cause inflammation. It could be
derived from histidine decarboxylation.
✓22. A neurotransmitter produced via the
hydroxylation and decarboxylation of
tryptophan.
✓23. An inactive precursor of an enzyme.
✓24. Another name for the enzyme that
catalyzes transamination reaction between
an amino acid and an alpha-keto acid.
✓3. A peptide derived from three amino
acids joined by two or sometimes three
peptide bonds.
✓4. The compound is formed by
transferring carbamoyl portion of carbamoyl
phosphate to ornithine by ornithine
transcarbamylase (OTC). The compound
formed is released into the cytosol for use
in the rest of the steps of the urea cycle.
✓5. An inherited condition that causes urine
to turn black when exposed to air, due to
the fact that the body could not breakdown
the amino acids phenylalanine and tyrosine.
✓6. An inborn error of metabolism caused
by a deficiency of phenylalanine
hydroxylase.
✓7. An enzyme that catalyzes the cleavage
of amino acids from the amino terminus of
protein or peptide substrates.
✓8. Describes an amino acid that can be
degraded directly into acetylCoA, and
ultimately acetoacetyl-CoA.
✓10. One of the intermediate metabolites
of the urea cycle that is generated in the
cytosol from arginine and transported into
the mitochondria for following reactions.
✓11. A cycle of biochemical reactions in
which nitrogen from protein metabolism is
converted to urea. (2 words)
✓12. The main form of nitrogen transporter
between tissues.
✓14. An endopeptidase secreted by the
pancreas to aid in the digestion of foods.
Functions to activate other pancreatic
zymogens as well.
✓16. A reversible reaction that transfers an
amino group to a ketoacid to form new
amino acids.
✓18. Refers to the difference between the
amount of nitrogen taken in and the
amount excreted or lost. Mainly used to
evaluate nutritional balance. (2 words)
:
✓21. An essential metabolism cofactor
derived from Vitamin B6. (2 words)