>6B3Q_a Cryo-EM structure of human insulin degrading enzyme in complex with insulin [Homo sapiens]
MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPL
ALEGSLQKRGIVEQCCTSICSLYQLENYCN
>2KQP_A NMR Structure of Proinsulin [Homo sapiens]
FVNQHLCGSDLVEALYLVCGERGFFYTKPTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQ
LENYCN
>6PXV_D Cryo-EM structure of full-length insulin receptor bound to 4 insulin. 3D refinement was focused on the extracellular region. [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN
>6ZI8_A Chain A, Insulin [Bos taurus]
MALWTRLRPLLALLALWPPPPARAFVNQHLCGSHLVEALYLVCGERGFFYTPKARREVEGPQVGALELAGGPGAGGLEGP
PQKRGIVEQCCASVCSLYQLENYCN
>1EFE_A AN ACTIVE MINI-PROINSULIN, M2PI [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGFFYTPKTRRYPGDVKRGIVEQCCTSICSLYQLENYCN
>6U46_A Solution Structure of a Heat-Resistant Long-Acting Insulin Analog [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGFFYTPRTEEGSRRSRGIVEQCCRSICSLYQLENYCG
>5WDM_A An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGFFYTPETEEGPRRGIVEQCCHSICSLEQLENYCN
>2JZQ_A Design of an Active Ultra-Stable Single-Chain Insulin Analog 20 Structures [unidentified]
FVNQHLCGSDLVEALYLVCGERGFFYTDPTGGGPRRGIVEQCCHSICSLYQLENYCN
>1ZEI_A Cross-Linked B28 Asp Insulin [Sus scrofa]
FVNQHLCGSHLVEALYLVCGERGFFYTDKAAKGIVEQCCTSICSLYQLENYCN
>6INS_E X-Ray Analysis Of The Single Chain B29-A1 Peptide-Linked Insulin Molecule. A Completely Inactive Analogue [Sus scrofa]
FVNQHLCGSHLVEALYLVCGERGFFYTPKGIVEQCCTSICSLYQLENYCN
>5WBT_A Solution Structure and Dynamics of an Ultra-Stable Single-Chain Insulin Analog STUDIES OF AN ENGINEERED MONOMER AND IMPLICATIONS FOR RECEPTOR BINDING [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGFFYTDPTEEGPRRGIVEQCCHSICSLEQLENYCN
>1SJU_A MINI-PROINSULIN, SINGLE CHAIN INSULIN ANALOG MUTANT: DES B30, HIS(B 10)ASP, PRO(B 28)ASP AND PEPTIDE BOND BETWEEN LYS B 29 AND GLY A 1, NMR, 20 STRUCTURES [Homo sapiens]
FVNQHLCGSDLVEALYLVCGERGFFYTDKGIVEQCCTSICSLYQLENYCN
>6K59_B Structure of Glargine insulin in 20% acetic acid-d4 (pH 1.9) [synthetic construct]
FVNQHLCGSHLVEALYLVCGERGFFYTPKTRR
>2KXK_B Human Insulin Mutant A22Gly-B31Lys-B32Arg [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGFFYTPKTKR
>2LGB_B Modified A22Gly-B31Arg Human Insulin [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGFFYTPKTR
>5MHD_B Biosynthetic engineered A22S-B3K-B31R human insulin monomer structure in water/acetonitrile solutions. [Homo sapiens]
FVKQHLCGSHLVEALYLVCGERGFFYTPKTR
>1AI0_B R6 HUMAN INSULIN HEXAMER (NON-SYMMETRIC), NMR, 10 STRUCTURES [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGFFYTPKT
>1IZA_B Role Of B13 Glu In Insulin Assembly: The Hexamer Structure Of Recombinant Mutant (B13 Glu-> Gln) Insulin [Sus scrofa]
FVNQHLCGSHLVQALYLVCGERGFFYTPKT
>4UNE_B Human insulin B26Phe mutant crystal structure
FVNQHLCGSHLVEALYLVCGERGFFFTPKT
>1HLS_B NMR STRUCTURE OF THE HUMAN INSULIN-HIS(B16) [Homo sapiens]
FVNQHLCGSHLVEALHLVCGERGFFYTPKT
>1B9E_B Human Insulin Mutant Serb9glu [Homo sapiens]
FVNQHLCGEHLVEALYLVCGERGFFYTPKT
>2MVD_B Solution structure of [GlnB22]-insulin mutant at pH 1.9 [Homo sapiens]
FVNQHLCGSHLVEALYLVCGEQGFFYTPKT
>1APH_B CONFORMATIONAL CHANGES IN CUBIC INSULIN CRYSTALS IN THE PH RANGE 7-11 [Bos taurus]
FVNQHLCGSHLVEALYLVCGERGFFYTPKA
>1UZ9_B Crystallographic and solution studies of N-lithocholyl insulin: a new generation of prolonged-acting insulins. [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGFFYTPK
>1QIY_B Human Insulin Hexamers With Chain B His Mutated To Tyr Complexed With Phenol [Homo sapiens]
FVNQYLCGSHLVEALYLVCGERGFFYTPKT
>1ZEG_B Structure Of B28 Asp Insulin In Complex With Phenol [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGFFYTDKT
>3V1G_B Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health [Homo sapiens]
FVNQHLCGSHLVEALYLVCGXRGFFYTPKT
>3JSD_B Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus [synthetic construct]
FVNQHLCXSHLVEALYLVCGERGFFYTPKT
>1W8P_B Structural properties of the B25Tyr-NMe-B26Phe insulin mutant. [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGFYFTPKT
>2M2M_B Structure of [L-HisB24] insulin analogue at pH 1.9 [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGHFYTPKT
>3BXQ_B The structure of a mutant insulin uncouples receptor binding from protein allostery. An electrostatic block to the TR transition
FVNQRLCGSHLVEALYLVCGERGFFYTPKT
>5HPR_B Insulin with proline analog HyP at position B28 in the T2 state [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGFFYTXKT
>3ZQR_B NMePheB25 insulin analogue crystal structure [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGFXYTPKT
>2M2O_B Structure of [D-HisB24] insulin analogue at pH 1.9 [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGXFYTPKT
>2WRX_B Semi-synthetic analogue of human insulin NMeAlaB26-insulin at pH 3.0 [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGFFXTPKT
>4UNG_B Human insulin B26Asn mutant crystal structure [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGFFNTPKT
>1HIQ_B PARADOXICAL STRUCTURE AND FUNCTION IN A MUTANT HUMAN INSULIN ASSOCIATED WITH DIABETES MELLITUS [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGSFYTPKT
>1MHI_B THREE-DIMENSIONAL SOLUTION STRUCTURE OF AN INSULIN DIMER. A STUDY OF THE B9(ASP) MUTANT OF HUMAN INSULIN USING NUCLEAR MAGNETIC RESONANCE DISTANCE GEOMETRY AND RESTRAINED MOLECULAR DYNAMICS [Homo sapiens]
XVNQHLCGDHLVEALYLVCGERGFFYTPKT
>1HIT_B Receptor binding redefined by a structural switch in a mutant Human Insulin [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGGFYTPKT
>6TYH_B Four-Disulfide Insulin Analog A22/B22 [Homo sapiens]
FVNQHLCGSHLVEALYLVCGECGFFYTPKT
>4UNH_B Human insulin B26Gly mutant crystal structure [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGFFGTPKT
>6GV0_B Insulin glulisine [Homo sapiens]
FVKQHLCGSHLVEALYLVCGERGFFYTPET
>2INS_B THE STRUCTURE OF DES-PHE B1 BOVINE INSULIN [Bos taurus]
VNQHLCGSHLVEALYLVCGERGFFYTPKA
>4A7E_B X-ray crystal structure of porcine insulin flash-cooled at high pressure [Sus scrofa]
FVNQHLCGSHLVEALYLVCGXRGFFYTPKA
>6CK2_B Insulin analog containing a YB26W mutation [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGFFWTPXT
>1QIY_D Human Insulin Hexamers With Chain B His Mutated To Tyr Complexed With Phenol [Homo sapiens]
XVNQYLCGSHLVEALYLVCGERGFFYTPKT
>4NIB_B Crystal structure of human insulin mutant B20 D-ala, B23 D-ala
FVNQHLCGSHLVEALYLVCXERXFFYTPKT
>5AZZ_B Crystal structure of seleno-insulin [Bos taurus]
FVNQHLXGSHLVEALYLVCGERGFFYTPKAM
>6S4I_B Crystal structure of zinc free A14E, B25H, B29K(N(eps)-[2-(2-[2-(2-[2-(Octadecandioyl-gamma-Glu)amino]ethoxy)ethoxy]acetylamino)ethoxy]ethoxy)acetyl]), desB30 human insulin [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGFHYTPK
>5BPO_B Human insulin with intra-chain chemical crosslink between modified B27 and B29 [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGFFYXPXT
>4P65_B Crystal structure of an cyclohexylalanine substituted insulin analog.
FVNQHLCGSHLVEALYLVCGERGXFYTPXT
>2N2V_B Solution structure of [B26-B29 triazole cross-linked]-insulin analogue at pH 1.9 [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGFFXTPXT
>1LPH_B Lys(B28)pro(B29)-Human Insulin [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGFFYTKPT
>1JCO_B Solution structure of the monomeric [Thr(B27)->Pro,Pro(B28)->Thr] insulin mutant (PT insulin) [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGFFYPTKT
>3U4N_B A novel covalently linked insulin dimer [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGFCYTPK
>1HO0_A NEW B-CHAIN MUTANT OF BOVINE INSULIN
FVNQHLSGSHLVEALYLVSGERGFFYTPKA
>1MHJ_B SOLUTION STRUCTURE OF THE SUPERACTIVE MONOMERIC DES-[PHE(B25)] HUMAN INSULIN MUTANT. ELUCIDATION OF THE STRUCTURAL BASIS FOR THE MONOMERIZATION OF THE DES-[PHE(B25)] INSULIN AND THE DIMERIZATION OF NATIVE INSULIN [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGFYTPKT
>5BQQ_B Human insulin with intra-chain chemical crosslink between modified B27 and B30 [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGFFYXPGX
>1HTV_B Crystal Structure Of Destripeptide (B28-B30) Insulin [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGFFYT
>1SJT_B MINI-PROINSULIN, TWO CHAIN INSULIN ANALOG MUTANT: DES B30, HIS(B 10)ASP, PRO(B 28)ASP, NMR, 20 STRUCTURES [Homo sapiens]
FVNQHLCGSDLVEALYLVCGERGFFYTDK
>1T0C_A Solution Structure of Human Proinsulin C-Peptide [Homo sapiens]
EAEDLQVGQVELGGGPGAGSLQPLALEGSLQ
>4EFX_B Highly biologically active insulin with additional disulfide bond [Homo sapiens]
FVNCHLCGSHLVEALYLVCGERGFFYTP
>2MPG_B Solution structure of the [AibB8,LysB28,ProB29]-insulin analogue [Homo sapiens]
FVNQHLCXSHLVEALYLVCGERGFFYTKPT
>1K3M_B NMR STRUCTURE OF HUMAN INSULIN MUTANT ILE-A2-ALA, HIS-B10-ASP, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES
FVNQHLCGSDLVEALYLVCGERGFFYTKPT
>2N2X_B Solution structure of [GlyB24,B27-B29 triazole cross-linked]-insulin analogue at pH 1.9 [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGGFYXPXT
>1A7F_B INSULIN MUTANT B16 GLU, B24 GLY, DES-B30, NMR, 20 STRUCTURES [Homo sapiens]
FVNQHLCGSHLVEALELVCGERGGFYTPK
>6X4X_B B24Y DKP insulin [Homo sapiens]
FVNQHLCGSDLVEALYLVCGERGYFYTKPT
>3ZS2_B TyrB25,NMePheB26,LysB28,ProB29-insulin analogue crystal structure [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGFYXTKPT
>1T1P_B NMR STRUCTURE OF HUMAN INSULIN MUTANT HIS-B10-ASP, VAL-B12-THR, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES
FVNQHLCGSDLTEALYLVCGERGFFYTKPT
>1T1K_B NMR STRUCTURE OF HUMAN INSULIN MUTANT HIS-B10-ASP, VAL-B12-ALA, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES
FVNQHLCGSDLAEALYLVCGERGFFYTKPT
>2HHO_B NMR structure of human insulin mutant GLY-B8-SER, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures [Homo sapiens]
FVNQHLCSSDLVEALYLVCGERGFFYTKPT
>2L1Y_B NMR Structure of human insulin mutant GLY-B20-D-ALA, GLY-B23-D-ALA PRO-B28-LYS, LYS-B29-PRO, 20 Structures [Homo sapiens]
FVNQHLCGSHLVEALYLVCXERXFFYTKPT
>1T1Q_B NMR STRUCTURE OF HUMAN INSULIN MUTANT HIS-B10-ASP, VAL-B12-ABA, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES
FVNQHLCGSDLXEALYLVCGERGFFYTKPT
>2KJU_B NMR structure of human insulin mutant glu-b21-d-glu, his-b10 asp pro-b28-lys, lys-b29-pro, 20 structures [Homo sapiens]
FVNQHLCGSDLVEALYLVCGXRGFFYTKPT
>2HH4_B NMR structure of human insulin mutant GLY-B8-D-SER, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures [Homo sapiens]
FVNQHLCXSDLVEALYLVCGERGFFYTKPT
>2K9R_B Enhancing the activity of insulin by stereospecific unfolding [Homo sapiens]
FVNQHLCGSDLVEALYLVCGERGXFYTKPT
>2MLI_B NMR structure of B25-(alpha, beta)-dehydro-phenylalanine insulin [Homo sapiens]
FVNQHLCGSDLVEALYLVCGERGFXYTKPT
>2K91_B Enhancing the activity of insulin by stereospecific unfolding [Homo sapiens]
FVNQHLCGSDLVEALYLVCGERGAFYTKPT
>1HIS_B Structure and dynamics of des-pentapeptide-insulin in solution: the molten-globule hypothesis. [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGFF
>2H67_B NMR structure of human insulin mutant HIS-B5-ALA, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures [Homo sapiens]
FVNQALCGSDLVEALYLVCGERGFFYTKPT
>1BZV_B [D-ALAB26]-DES(B27-B30)-INSULIN-B26-AMIDE A SUPERPOTENT SINGLE-REPLACEMENT INSULIN ANALOGUE, NMR, MINIMIZED AVERAGE STRUCTURE [synthetic construct]
FVNQHLCGSHLVEALYLVCGERGFFX
>6S4J_B Crystal structure of zinc free A14E, B25H, B29K(N(eps)-[2-(2-[2-(2-[2-(Octadecandioyl-gamma-Glu)amino]ethoxy)ethoxy]acetylamino)ethoxy]ethoxy)acetyl]), desB27, desB30 human insulin [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGFHYPK
>2WS4_B Semi-synthetic analogue of human insulin ProB26-DTI in monomer form [Homo sapiens]
FVNQHLCGSHLVEALYLVCGERGFFP
>2MPI_B Solution structure of B24G insulin [Homo sapiens]
FVNQHLCGSDLVEALYLVCGERGGFYTKPT
>1HUI_B INSULIN MUTANT (B1, B10, B16, B27)GLU, DES-B30, NMR, 25 STRUCTURES [Homo sapiens]
EVNQHLCGSELVEALELVCGERGFFYEPK
>1SDB_B Porcine Desb1-2 Despentapeptide(B26-B30) Insulin [Sus scrofa]
NQHLCGSHLVEALYLVCGERGFF
>1DEI_B DESHEPTAPEPTIDE (B24-B30) INSULIN [Sus scrofa]
FVNQHLCGSHLVEALYLVCGERG
>2QIU_A Structure of Human Arg-Insulin [Homo sapiens]
RGIVEQCCTSICSLYQLENYCN
>3LRI_A Solution structure and backbone dynamics of long-[Arg(3)]insulin-like growth factor-I [Homo sapiens]
MFPAMPLSSLFVNGPRTLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRACQTGIVDECCFRSCDLRRLEMYCAPLKPA
KSA
>2KXK_A Human Insulin Mutant A22Gly-B31Lys-B32Arg [Homo sapiens]
GIVEQCCTSICSLYQLENYCNG
>5MHD_A Biosynthetic engineered A22S-B3K-B31R human insulin monomer structure in water/acetonitrile solutions. [Homo sapiens]
GIVEQCCTSICSLYQLENYCNS
>2BN3_A Insulin before a high dose x-ray burn [Bos taurus]
GIVEQCCTSVCSLYQLENYCN
>1A7F_A INSULIN MUTANT B16 GLU, B24 GLY, DES-B30, NMR, 20 STRUCTURES [Homo sapiens]
GIVEQCCTSICSLYQLENYCN
>6VES_B Human insulin analog: [GluB10,HisA8,ArgA9]-DOI [Homo sapiens]
FVNQHLCGSELVEALYLVCGER
>1XW7_A Diabetes-Associated Mutations in Human Insulin: Crystal Structure and Photo-Cross-Linking Studies of A-Chain Variant Insulin Wakayama [synthetic construct]
GILEQCCTSICSLYQLENYCN
>6TYH_A Four-Disulfide Insulin Analog A22/B22 [Homo sapiens]
GIVEQCCTSICSLYQLENYCNC
>1BQT_A THREE-DIMENSIONAL STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR-I (IGF-I) DETERMINED BY 1H-NMR AND DISTANCE GEOMETRY, 6 STRUCTURES [Homo sapiens]
GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSA
>2JUM_A ThrA3-DKP-insulin [unidentified]
GITEQCCTSICSLYQLENYCN
>2JUU_A allo-ThrA3 DKP-insulin [unidentified]
GIXEQCCTSICSLYQLENYCN
>6UM2_B Structure of M-6-P/IGFII Receptor and IGFII complex [Homo sapiens]
MAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSRGIVEECCFRSCDLALLETYCATPAKSE