Module 1: Intro to Research and Evidence-Based Practice Research The systematic, rigorous, critical investigation that aims to answer questions about nursing phenomena. Evidence-Based Practice The collection, evaluation, and integration of valid research evidence, combined with clinical expertise and an understanding of patient and family values and preferences, to inform clinical decision making. Steps of Evidence-Based Practice (p. 14 in book) Ask→ Gather → Assess and Appraise → Act → Evaluate Quality Improvement The systematic use of data to monitor the outcomes of care processes as well as the use of improvement methods to design and test changes in practice for the purpose of continuously improving the quality and safety of health care systems. Critical Appraisal Skills Nurses must be knowledgeable consumers of research, who can evaluate the strengths and weaknesses of research evidence and use existing standards to determine the merit and readiness of research for use in clinical practice. Clinical Guidelines Systematically developed statements or recommendations that serve as a guide for practitioners. There are two types of clinical guidelines that we will discuss: consensus (expert-developed) guidelines and evidencebased guidelines. Clinical Practice Guidelines Issued by third-party organizations, these guidelines define the role of specific diagnostic and treatment modalities in the diagnosis and management of patients. The statements contain recommendations that are based on evidence from a rigorous systematic review and synthesis of the published medical literature. Consensus Guidelines An agreement among experts about a certain approach to diagnose or treat a particular disease or condition. NonResearch design in which an investigator observes a phenomenon without experimental manipulating the independent variable(s). Research Design Experimental A research design that has the following properties: randomization, Research Design control, and manipulation. Systematic Review A summation and assessment of a group of research studies that test a similar research question. Meta-Analysis A summary of a number of studies focused on one question or topic, and uses specific statistical methodology to synthesize the findings in order to draw conclusions about the area of focus. Integrative Review A focused review and synthesis of research or theoretical literature in a particular focus area, and includes specific steps of literature integration and synthesis without statistical analysis. It can include both quantitative and qualitative articles. At times reviews use the terms systematic review and integrative review interchangeably. Meta-Synthesis and MetaSummary The synthesis of a number of qualitative research studies on a focused topic, using specific qualitative methodology. Module 2 Chapter 2: Research Questions, Hypotheses, and Clinical Questions Research question 3 Characteristics of a Good Research Question A key preliminary step wherein the foundation for a study is developed from the research problem and results in the research hypothesis. A question that tests a measurable relationship to be examined in a research study. 1. Clearly identifies the variables under consideration 2. It specifies the population being studied 3. Testability - it implies the possibility of empirical testing Hypothesis Predicts the outcome of the study. Theory A set of interrelated concepts, definitions, and propositions that present a systematic view of phenomena for the purpose of explaining and making predictions about those phenomena. Hypotheses provide a bridge between theory and the real world. Nursing Theory A creative and rigorous structuring of ideas that project a tentative, purposeful, and systematic view of phenomena. Through systematic inquiry, nurses develop knowledge relevant to improving the care of patients. Clinical question (will conduct a literature search to answer these questions) (p.49) A question that arises from clinical situations - or - the first step in the development of an EBP or QI project. Using similar criteria related to framing a research question, focused clinical questions form a basis for searching the literature to identify supporting evidence from research. 4 Components of a Clinical Question (PICO) (provides framework to help nurses develop an effective electronic literature search) (p. 49) 1. Population - The individual patient or group of patients with a particular condition or health care problem 2. Intervention - The particular aspect of health care that is of interest to the nurse (e.g. a therapeutic [inhaler or nebulizer for treatment of asthma], a preventative [pneumonia vaccine], a diagnostic [measurement of blood pressure], or an organizational [implementation of a bar coding system to reduce medication errors] intervention) 3. Comparison - Standard care or no intervention (e.g. no antibiotic comparison to ibuprofen for children with otitis media); a comparison of two treatment settings (e.g. rehabilitation center vs. home care) 4. Outcome - More effective outcome (e.g. improved glycemic control, decreased hospitalizations, decreased medication errors) Hypothesis (complex, research, statistical) A prediction about the relationship between two or more variables. Statistical: States that there is no relationship between the independent and dependent variables. The statistical hypothesis is also known as the null hypothesis. Complex: Number of variables Research: A statement about the expected relationship between the variables; also known as the scientific hypothesis Directional hypothesis Provides a direction of the relationship -- greater than, less than, positive, negative. Non directional hypothesis States a relationship, but no direction. Independent variable The variable that has the presumed effect on the dependent variable. In experimental research studies, the researcher manipulates the independent variable. In nonexperimental research, the independent variable is not manipulated and is assumed to have occurred naturally before or during the study. Dependent variable Varies with a change in the independent variable. The dependent variable is not manipulated. It is observed and assumed to vary with changes in the independent variable. It is the dependent variable that the researcher is interested in understanding, explaining, or predicting. Population A well-defined set that has certain characteristics and is either clearly identified or implied in the research question. Purpose The purpose of the study encompasses the aims or objectives the investigator hopes to achieve with the research (purpose, aims, and objectives are synonymous). Verbs such as discover, explore, or describe suggest investigation of an infrequently researched topic that might appropriately be guided by research questions rather than hypotheses. In contrast, verb statements indicating that the purpose is to test the effectiveness of an intervention or compare two alternative nursing strategies suggest a hypothesis-testing study for which there is an established knowledge base of the topic. Testability Measureable by either qualitative or quantitative methods. Chapter 4: Theoretical Frameworks for Research Two Major Components of Theories Concepts and Constructs -- convey they essential elements or ideas of a theory Concept Image or symbolic representation of an abstract idea; the key identified element of a phenomenon that is necessary to understand it. Concepts can be concrete or abstract. A concrete concept can be easily identified, quantified, or measured, whereas an abstract concept is more difficult to quantify or measure. For example, weight, blood pressure, and body temp are concrete concepts. Hope, uncertainty, and spiritual pain are more abstract concepts. In a study, resiliency is a relatively abstract concept. Construct A complex concept - combination of two or more concepts; constructs usually comprise more than one concept and are built or “constructed” to fit a purpose. Health promotion, maternalinfant bonding, health-seeking behaviors, and health-related quality of life are examples of constructs. Model A graphic or symbolic representation of a phenomenon. A graphic model is empirical and can be readily represented. A model of an eye or a heart is an example. A symbolic or theoretical model depicts a phenomenon that is not directly observable and is expressed in language or symbols. Written music or Einstein’s theory of relativity are examples of symbolic models. Theories used by nurses or developed by nurses often include symbolic models. Models are very helpful in allowing the reader to visualize key concepts/constructs and their identified interrelationships. Nursing Theories (situation-specific, middle range, grand) Grand Nursing Theories: Sometimes referred to as nursing conceptual models and include the theories/models that were developed to describe the discipline of nursing as a whole. This most abstract level of theory has established a knowledge base for the discipline of nursing. Middle Range: Limited number of concepts. More focused. Are more easily tested through research and more readily used as frameworks for research studies. Situation-Specific Nursing or Practice Theories: Narrow in scope, explain a small aspect of phenomena and processes of interest to nurses, and are usually limited to specific populations or fields of practice. Provide closer links to research and practice. Conceptual definition vs operational definition Conceptual Definition: Much like a dictionary definition, a conceptual definition conveys the general meaning of the concept. However, it goes beyond general language meaning found in the dictionary by defining or explaining the concept as it is rooted in theoretical literature. Operational Definition: Specifies how the concept will be measured. Defines what instruments will be used to assess the presence of the concept and will be used to describe the amount or degree to which the concept exists (e.g. operational definition for time = hours, minutes, seconds) Conceptual framework/theoretical framework These two terms are used interchangeably. The conceptual/theoretical framework refers to a structure that provides guidance for research or practice. The framework identifies the key concepts and describes their relationships to each other and to the phenomena (variables) of concern to nursing. It serves as the foundation on which a study can be developed or as a map to aid in the design of the study. Deductive vs inductive (p.74-75) Inductive: Generalizations are developed from specific observations. Theory generation uses inductive reasoning. We make many observations, discern a pattern, make a generalization, and infer an explanation or a theory. Deductive: The scientific method uses deduction to test hypotheses and theories. In deductive reasoning, we hold a theory and based on it we make a prediction of the consequences. That is, we predict what the observations should be if the theory were correct. We go from the general -- the theory -- to the specific -- the observations Module 3 Chapter 5: Introduction to Qualitative Research Qualitative research The study of research questions about human experiences. Help formulate an understanding of a phenomenon.Explanatory, descriptive, and inductive in nature. Context dependent An observation as defined by its circumstance or context. Ex: The experience of having a baby is not the same for any two women, and is definitely different for a disabled mother. Thus, qualitative researchers believe that reality is socially constructed and context dependent. Context independent The opposite of context dependent. (Ex: You would be able to give a description of a basketball because just the word alone would bring these ideas to mind). Data saturation A point when data collection can cease. It occurs when the information being shared with the researcher becomes repetitive. Ideas conveyed by the participant have been shared before by other participants; inclusion of new participants does not result in new ideas. Grand tour question A broad overview question.Types of interview questions in qualitative studies that seek “the big picture.” Inclusion and exclusion criteria Exclusion criteria: Those characteristic that restrict Inductive vs deductive Naturalistic setting An environment of familiar “day to day” surroundings. Commonly used for data collection in qualitative studies. Paradigm Pattern; it has been applied to science to describe the way people in society think about the world. All research is based on paradigm. Theme In the data analysis of qualitative studies, the goal is to find commonalities and differences in the interviews, and then group these into broader, more abstract, overarching categories of meaning called themes. Chapter 6 and 7: Qualitative Approaches to Research and Appraising Qualitative Research 4 Approaches to Qualitative Research 1. 2. 3. 4. Phenomenological Method Grounded Theory Method Ethnographic Method Case Study Method Phenomenological Method Process of learning and constructing the meaning of human experience through intensive dialogue with persons who are living the experience.The researcher’s goal is to understand the experience as it is lived by the participant. Phenomena and Phenomenology Phenomena: Those things that are perceived by our senses (e.g. pain, losing a loved one). Phenomenology: A qualitative research approach that aims to describe experience as it is loved through, before it is conceptualized. Lived experience The focus of the phenomenological method. In phenomenological research, a term used to refer to the focus on living through events and circumstances (prelingual), rather than thinking about these events and circumstances (conceptualized experience). Bracketing When using the phenomenological method, the researcher’s perspective is bracketed. This means that the researcher identifies their own personal biases about the phenomenon of interest to clarify how personal experience and beliefs may color what is heard and reported. Further, the phenomenological researcher is expected to set aside their personal biases--to bracket them--when engaged with the participants. . Ethnography/Ethnographic Method A qualitative research approach designed to produce cultural theory. Focus is on cultural or social groups and systems. Goal is to understand the emic view (insider’s view). Questions are around “lifeways” or patterns of behavior in a social group or culture. Data collected using documents, interviews and observation and include key informants. Data analysis begins with searching for domains. Nurses use the method to study cultural variations in health and patient groups as subcultures within larger social contexts. Grounded Theory Method An inductive approach that uses a systematic set of procedures to arrive at a theory about basic social processes.Grounded theory describes a research approach to construct theory where no theory exists, or in situations where existing theory fails to provide evidence to explain a set of circumstances. Grounded Theory Theory that is constructed inductively from a base of observations if the world as it is lived by a selected group of people. Theoretical Sampling A tool used in the grounded theory method of qualitative research that allows data collection and analysis to occur simultaneously. Hunches about emerging patterns in the data are noted in memos that the researcher uses to direct activities in fieldwork. Used to select experiences that will help the researcher to test hunches and ideas and to gather complete information about developing concepts. Constant comparative method A process of continuously comparing data as they are acquired during research with the grounded theory method. Case Study Method Studying the peculiarities and commonalities of a specific case, irrespective of the actual strategies for data collection and analysis that are used to explore research questions. Include quantitative or qualitative data but are defined by their focus on uncovering an individual case and, in some instances, identifying patterns in variables that are consistent across a set of case studies. Emic vs Etic views Emic Views: A native’s or insider’s view of the world. Etic Views: An outsider’s view of another’s world. Mixed Methods Research The use of both qualitative and quantitative methods in one study. Community-Based Participatory research A research method that systematically accesses the voice of a community to plan context-appropriate action. Change or action is the intended end product. Saturation See data saturation Ways to Synthesize Qualitative Research Meta-analysis and meta-summary Meta-summary Qualitative meta-summary is a quantitatively oriented aggregation of qualitative findings that are topical or thematic summaries or surveys of data. Meta-synthesis (p. 117) Qualitative meta-synthesis is an interpretive integration of qualitative findings that are interpretative syntheses of data, including phenomenologies, ethnographies, grounded theories, and other integrated and coherent descriptions of phenomena, events, or cases that are the hallmarks of qualitative research. They offer a description or explanation of a target event or experience, instead of a summary of unlinked features. Issues in Qualitative Research (p. 118) 1. Ethics - Protection of human subjects is a critical aspect of all scientific investigation a. Naturalistic Setting - The need to gain informed consent b. Emergent Nature of Design - Planning for questioning and observation emerges over the time of the study. Thus it is difficult to inform the participant precisely of all potential threats before he or she agrees to participate. c. Research-Participants Interaction Relationships developed between the researcher and participant may blur the focus of the interaction. d. Researcher as Instrument - The researcher is the study instrument, collecting data and interpreting the participant’s reality. 2. Credibility, Auditability, and Fittingness - Quantitative studies are concerned with reliability and validity of instruments, as well as internal and external validity criteria as measures of scientific rigor. The rigor of qualitative methodology is judged by unique criteria appropriate to the research approach. Criteria for Appraisal of Scientific Rigor (in qualitative research) 1. Auditability 2. Fittingness 3. Credibility Auditability Accountability as judged by the adequacy of information leading the reader from the research question and raw data through various steps of analysis to the interpretation of findings. For instance, you should be able to follow the reasoning of the researcher step by step through explicit examples of data, interpretations, and syntheses. Fittingness Faithfulness to participants’ everyday reality, described in enough detail so that others can evaluate importance for practice, research, and theory development. For instance, you will know enough about the human experience being reported that you can decide whether it “rings true” and is useful for guiding your practice. Credibility Truth of findings as judged by participants and others within the discipline. For instance, you may find the researcher returning to the participants to share interpretation of findings and query accuracy from the perspective of the persons living the experience. Module 4 Chapter 3: Gathering and Appraising the Literature Boolean operator (p.59) Words used to define the relationship between words or group of words during a literature search. Ex. AND, OR, NOT, NEAR Citation management software Software that forms citations and creates references pages for you Controlled vocabulary Most databases have a section for controlled vocabulary you can search through, these are terms/keywords to help you conduct an efficient search for the correct articles. You can use these keywords to see how the terms of your question match up, and then add them to your search. Electronic database From an EBP perspective, you need to retrieve all the studies available on your topic/clinical question. To understand the literature in a specific area requires a review of all relevant studies. Grey literature (p.55) Information produced by government, industry, health care organizations, and professional organizations in the form of committee reports and policy documents. Ex. a dissertation Literature review (Narrative Review) Systematic and critical appraisal of the most important literature on a topic. Also called: introduction, background, conceptual framework, theoretical framework. Pre-appraised synopsis (p.52) -Secondary source! -an expert's comment about someone else's research. -These usually include a commentary regarding the strengths and applicability of the evidence to a patient population Primary and secondary sources (p. 47) Primary: research articles, theoretical documents, or other documents used by the author who is conducting the study, developing a theory or writing an autobiography Secondary: Published articles or books written by persons other than the individual who conducted the research study or developed the theory Peer reviewed journals (p.55) -Should be your primary sources for theoretical, clinical, or research articles. -Has a panel of internal and external reviewers that review the submitted manuscript. Web browser (p.56) Internet explorer, mozilla, firefox, chrome, safari, etc. Chapter 11 AGREE II (p.220) One of the most widely used instruments to evaluate the applicability of guidelines to practice Clinical practice guidelines (p.219) Systematically developed statements or recommendations that link research and practice and serve as a guide for practitioners. Can be evidence-based or expert-based Evidencebased practice guidelines Practice guidelines developed using a scientific process Expert-based practice guidelines Not all areas of clinical practice have a sufficient research base, that’s where expert based guidelines come in. These guidelines depend on having a group of experts who meet and use opinions of experts along with whatever research evidence is available to date. Effect size A meta-analysis takes the effect size from each of the studies reviewed to obtain an estimate of the population (or the whole) to create a single effect size of all the studies. In a meta-analysis, the effect size is an estimate of how large of a difference there is between intervention and control groups in the summarized studies. Forest plot (blobbogram) Graph (used in meta-analysis) that depicts the study results. LINK THAT BREAKS DOWN HOW TO READ: https://s4be.cochrane.org/blog/2016/07/11/tutorial-read-forest-plot/ Integrative review Critical reviews of an area of research without a statistical analysis or a theory synthesis. The most broad category of reviews. Meta-analysis Also referred to as a systematic review, but the only studies that are metaanalyses are those that reviewed studies using statistical methods. Systematic review Simply put, a systematic review refers to the entire process of selecting, evaluating, and synthesizing all available evidence, while the term meta-analysis refers to the statistical approach to combining the data derived from a systematic-review. Assessment of research studies found in the literature based on a clearly focused question that uses explicit criteria to identify, select, critically appraise and analyze relevant data. MetaSynthesis Metasynthesis—the systematic review and integration of findings from qualitative studies—is an emerging technique in medical research that can use many different methods. Integrates qualitative research findings on a topic and is based on comparative analysis and interpretive synthesis
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