Uses of radioisotopes Atoms of an element come in different forms called isotopes, with each isotope having the same number of protons and electrons but different numbers of neutrons. Some of these isotopes have an unstable nucleus, and at some point will randomly decay into a more stable atom. They do so my releasing energy or particles called radiation, and are therefore called radioisotopes (= radioactive isotopes, see Figure 1). While this radiation can be very dangerous to humans, it can also be put to many different uses, including carbon dating, nuclear power and medical imaging. Figure 1: Unstable atoms spontaneously decay into more stable isotopes by releasing radiation. This radiation can take 3 forms: alpha (helium nucleus), beta (high energy electron) or gamma (electromagnetic wave). Decay of uranium-235 produces alpha, decay of carbon-14 produces beta and decay of technetium99 produces gamma. Half-life and carbon dating: Throughout their lives organisms consume different isotopes of carbon, primarily the stable Carbon-12. However, small amounts of unstable Carbon-14 is also consumed and build up in the body. When the organism dies it has a certain amount of Carbon-14 in its body, which will slowly decay over time into more stable Nitrogen-14 atoms, releasing β radiation in the process (Fig 1). Because the decay of radioisotopes is random, scientists describe the process using the term “half-life”. The half-life is the length of time needed for 50% of the atoms to decay. As scientists know the half-life of Carbon-14 (approximately 5000 years), if they measure the amount of Carbon-14 in a dead organism they can determine how long ago it died. Mass number = no. protons + no. neutrons A Z X Atomic number = # protons Element symbol For example, if scientists find a skull and measure that there is 2.5g of Carbon-14 and 2.5g of Nitrogen-14 in it they know the organism died approximately 1 half-life ago i.e. about 5000 years (Fig. 2). Figure 4: The three types of radiation differ in their penetration power. As alpha (α) is a large particle it cannot penetrate tissue and is only dangerous if ingested/inhaled. Beta (β) is smaller and thus can penetrate further, causing buns to skin and more damage if ingested. Because gamma (γ) is a high energy electromagnetic wave it is the most dangerous as it can penetrate into the body and cause internal damage to cells. Medical imaging: Radioisotopes are commonly used in medicine, both to produce images of parts of the body or treat different diseases. The most common form of imaging is X-rays, where high energy radiation is released, penetrating through part of the body, and is then detected on the other side. However, other forms of imaging also use radioisotopes. Doctors can have patient ingest, inhale or be injected with a radioisotope. Certain types of cancers will consume large amounts of the isotope, which then releases gamma radiation. This radiation can be detected by a gamma camera, showing the cancer as a bright area (Fig 4). This allows doctors to diagnose cancer and identify where it is in the body. Nuclear power: Nuclear reactors use radiation released by radioisotopes to provide power to vehicles and cities. The reactor consists of a radioisotope fuel, control rods, a cooling system and a turbine (Fig 5). The most common fuel is uranium-235, with a half life of around 700 million years. Within the reactor it undergoes a process called nuclear fission, releasing several types of radiation. This radiation has large amounts of energy, heating up the water surrounding the fuel, which in turn makes steam that drives a turbine. The movement of the turbine is then converted into electricity, and can be used to power submarines, factories and cities. To reduce the harm caused by radiation an isotope with a short half-life is used. The most commonly used isotope is technetium-99 with a half life of only 6 hours (Fig 1). Reactors need to be carefully managed. The heat from the decay needs to be controlled using rods that absorb the radiation and a cooling system. A meltdown occurs if the control rods or cooling system fails, as occurred in Fukushima after an earthquake in 2011. Figure 5 : radioisotope imaging, with bright areas showing high levels of radiation released by technetium-99. The brain and kidneys normally take up large amounts, but the bright spot on the chest is abnormal, suggesting cancer. Figure 6: major components of nuclear reactor, including fuel elements (uranium-235), control rods and a cooling system. Figure 2: decay of Carbon-14, with only 50% remaining after each half life (5,000 years) Figure 3: isotopes are represented using isotope notation, which includes the element symbol (X), mass number (A) and atomic number (Z) of the atom. Each isotope is referred to by joining the symbol X and mass number A in the form X-A (e.g. a Hydrogen isotope with mass number of 2 is called Hydrogen-2).