10HS Biology_Revision Session 1_Classwork Revision Session 1 – Sections 8.1 – 8.3 1. Complete the table of researchers and their experiments that contributed to the understanding of DNA as genetic material Scientists, Year Frederick Griffith, 1928 Oswald Avery, 1944 Alfred Hershey & Martha Chase, 1952 Experiment Outcome Conclusion 10HS Biology_Revision Session 1_Classwork 2. What did these scientists contribute to our understanding of DNA structure? Scientists Contributions Franklin & Wilkins Erwin Chargaff Watson & Crick 3. Work out the missing percentages Organism Human Chicken Rat E. coli %A 29.3 28.0 28.4 %G 20.7 21.4 26.9 4. How many hydrogen bonds are between A and T? C and G? 5. Label the nucleotide 1 2 3 %C 20.0 21.6 26.9 %T 30.0 10HS Biology_Revision Session 1_Classwork 6. Label the DNA strand 1 2 3 4 5 6 7. Identify the two types of bonding in the DNA strand and where they are found 8. Complete the complementary strand A A T T G G C C G G 10HS Biology_Revision Session 1_Classwork 9. Compare and contrast purines and pyrimidines Purines Pyrimidines 10. Complete the sentences a. DNA replication occurs in the ________ of eukaryote cells b. DNA Replication occurs during __________ of the cell cycle c. It is important because DNA must divide before _______ and ________. 11. List the steps of DNA replication shown below 1 2 3 4 5 10HS Biology_Revision Session 1_Classwork 12. What do these enzymes do during DNA replication? Helicase Primase DNA polymerase Ligase 13. Complete these sentences a. DNA polymerase can only synthesize _______ direction b. On the ________ strand, DNA polymerase is moving away from the __________ fork c. Therefore, it must constantly return to copy newly separated stretches of DNA called ________________ 14. Which of these represents semi-conservative replication? Why? 15. What is the benefit of proofreading?