Station โ 3 "Management of emergency conditions in the clinic of internal medicine." Situational task 1 Patient V., male, 56 years old. The patient is treated in the cardiology department. The patient has dilated cardiomyopathy. The patient suddenly lost consciousness in the corridor of the department. Non-smoker. Alcohol does not abuse. Objectively. The general condition is very serious: the patient is noncontact, does not answer questions, there is no pulsation on the carotid arteries, there is no breathing. Blood pressure is absent. ECG: Isoline, QRS absent. Tasks: 1. Formulate a preliminary diagnosis. 2. Identify patient management tactics and provide emergency care by naming groups of drugs and a representative according to an existing algorithm. ANSWERS: Diagnosis: Sudden cardiac death Asystole Tactics: CPR 30:2 Intubation Oxygen therapy Intravenous or intraosseous access Epinephrine 1mg (1-3 mg), every 3-5 minutes + CPR Situational task 2 Patient A., female, 58 years old. An emergency medical team is called to the patient. The patient has an intense headache in the occipital region, numbness of the left hand and slow speech. The patient had high blood pressure 170/95 mm Hg. She did not take medication regularly, occasionally - captopril. Complaints appeared after stress at work. Objectively. The general condition is severe, inhibited. Hypersthenic patient. The body mass index is 35.5 kg /m2. The skin is clean. S1 is moderately weakened at the apex of the heart. Aortic accent of S2. Above the lungs - vesicular breathing. Abdomen is soft, painless. Body temperature: 36.5 ° C ECG: rhythm is sinus, 80/min. P-Q - 0.14 msec, QRS - 0.09 msec, Q-T 0.36 msec. Left ventricular hypertrophy. MRI of the brain: ischemic stroke of the right hemisphere of the brain Tasks: 1. Formulate a preliminary diagnosis. 2. Identify patient management tactics and provide emergency care by naming a groups of drugs and a representative according to an existing algorithm. ANSWERS: Diagnosis: Arterial hypertension 3rd stage, 3rd degree Emergency hypertensive crises Ischemic stroke Tactics: Hospitalization and thrombolysis (Alteplase) Neuroprotection (citicoline) Control of glucose level and body temperature Target level of BP: 185/100 (decrease not more than 25%) Drugs: Labetalol (Beta-Blocker) Enalaprilat (ACE inhibitor) Urapidil (Alpha adrenoreceptor inhibitor) Nicardipine (Calcium channel blocker) Situational task 3 Patient I., man, 42 years old. An ambulance team were called to the patient. The patient complained to intense headache in the occipital region, flashing "flies" before the eyes, dizziness. In the anamnesis patient had hypotermia and acute pharyngitis 2 weeks ago. 2 days ago appeared edema under the eyes, decreased urine excretion to 700 ml and changed color of urine - "meat mud". Objectively. The general condition is severe. The patient is having convulsions during the examination. The skin is clean. In the lungs vesicular breathing. Borders of the heart are not changed. Abdomen is painless. Pasternacky symptom is negative. Body temperature: 36.5°C. Respiratory rate: 20/min. Heart beat: 88/min., rhythmical. Blood pressure 245/130 mm Hg Urinalysis: Indicator Color Reaction Specific gravity Protein, g/L Sugar WBC, in visual field RBC, in visual field Epithelial cells, in sight Cylinders (microscopy), in sight Result meat slop 7,5 1.021 0,099 absent 3-4 40-50 single absent Reference values straw yellow 4,6-8,0 1.010-1.025 absent absent for man 0-5 for man 0-1 0-10 absent ECG: rhythm is sinus, HR 86/min. PQ - 0.16 msec, QRS - 0.09 msec, QT 0.36 msec. Nonspecific diffuse changes in the left ventricle. Tasks: 1. Formulate a preliminary diagnosis. 2. Identify patient management tactics and provide emergency care by naming a group of drugs and a representative according to an existing algorithm. ANSWERS: Diagnosis: Acute glomerulonephritis Nephritic syndrome Secondary arterial hypertension Emergency hypertensive crisis Eclampsia Tactics: Sibazon / Diazepam (benzodiazepines) Target BP: 150/100 or 140/100 Labetalol (beta blocker) Urapidil (Alpha adrenoreceptor inhibitor) Magnesium Sulfate (I/V) Furosemide 40-80mg (I/V) or Torsemide 4mg (I/V) Situational task 4 Patient M., 62 years old, called the ambulance for complaints of headache, shortness of breath, turning into suffocation, pressing pain in the heart area. This condition developed acutely 30 minutes ago after severe stress. The patient has taken captopril 25 mg. Anamnesis: hypertension in the last 6 years. The patient constantly takes antihypertensive drugs (ACE inhibitor (enalapril 20 mg) and diuretic (hydrochlorothiazide 12.5 mg)). Physical examination: patient's condition is grave. The patient is agitated, scared, breathes heavily, half-sitting position in bed. Pulse - 92/min, rhythmic. Auscultation: SI is soft, accentuation of SII on the pulmonary artery, additional SIII (gallop rhythm). BP - 180/120 mm Hg. Lungs percussion - shortening of percussion sound over the lower parts of the lungs, auscultation - moist fine rales and decreased vesicular breathing over the lower parts of the lungs. Respiratory rate - 20 / min. Examination of the abdomen - no pathological changes were found. Peripheral edema is absent. ECG. Sinus rhythm, heart rate 94 / min. Left axis deviation. Signs of left ventricular hypertrophy (RV5 and RV6> RV4; SV1 + RV6> 35 mm). In the left chest leads V5, V6 - ST segment depression 2 mm below the isoline. Troponin I - 0.25 ng / ml (N <0.5 ng / ml). Task: 1. Formulate a preliminary diagnosis. 2. Identify patient management tactics and provide emergency care by naming a groups of drugs and a representative according to an existing algorithm. ANSWERS: Diagnosis: Arterial hypertension 3rd stage, 3rd degree Emergency hypertensive crises Complicated by pulmonary edema (Killip 3 rd stage) Tactics: Hospitalization Target BP: 25% decrease during the first hour Nitroglycerine (I/V), Nitroprusside (I/V) Furosemide 40-80mg (I/V) or Torsemide 4mg (I/V) Oxygen therapy Situational task 5 Patient S., 52 years old, man, driver. The ambulance was called due to the prolonged (lasts 30 minutes) intensive burning pain behind the sternum with irradiation in the epigastric area. Admission of nitroglycerin was no effective. The pain arose acutely during exercise. Anamnesis - no previous cardiac complaints. Smoker 25 years. Physical examination. General condition of moderate severity, patient is excited. Pulse - 94 per minute, rhythmic. Heart sounds are rhythmic; SI is soft. BP - 140/70 mm Hg. Examination of the lungs and abdominal organs no pathological changes. Peripheral edema is absent. ECG. In leads II, III, and AVF - elevation of the ST segment on 4 mm above the isoline. Troponin I - 1.20 ng / ml (0.04 ng / ml - norm). Task: 1. Formulate a preliminary diagnosis. 2. Identify patient management tactics and provide emergency care by naming a groups of drugs and a representative according to an existing algorithm. ANSWERS: Diagnosis: Acute coronary syndrome STEMI Acute stage Posterior wall Cardiogenic shock (BUT in normal circumstances BP should be lower than 90/60) Tactics: Hospitalization in PCI (Pre Cutaneous Intervention) center PCI Thrombolytic therapy (tenecteplase, Streptokinase and Metalisa) (Shock therapy) Dobutamine and dopamine Noradrenaline (vasopressin) Oxygenation Morphine Aspirin (300mg) and Clopidogrel (600 mg) Heparine or enoxiparine (I/V) Situational task 6 Patient M., 53 years old, called the ambulance for complaints of headache and pressing pain in the heart area. These complaints appeared suddenly 20 minutes ago after severe stress. The patient has taken captopril 25 mg and nitroglycerin 0.5 mg, but his condition did not improve. Anamnesis: hypertension in the last 3 years. The patient periodically took antihypertensive drugs (i-ACE (lisinopril 20 mg)) with an increase of BP. Physical examination: patient's condition is moderate severe, "fear of death." Pulse - 90 / min, rhythmic. Heart auscultation - SI is soft, aortic accentuation of SII. BP - 180/110 mm Hg. Respiratory rate - 18 / min. SpO2 - 90%. Examination of the lungs and abdominal organs revealed no pathological changes. Peripheral edema is absent. ECG. Sinus rhythm, heart rate 90 / min. Left axis deviation. Signs of left ventricular hypertrophy (RV5 and RV6> RV4; SV1 + RV6> 35 mm). In the chest leads (V1 - V6) - ST segment depression 2 mm below the isoline, negative T wave. Task: 1. Formulate a preliminary diagnosis. 2. Identify patient management tactics and provide emergency care by naming a groups of drugs and a representative according to an existing algorithm. ANSWERS Diagnosis: Arterial hypertension 3rd stage, 3rd degree Emergency hypertensive crises Acute coronary syndrome NSTEMI ? Tactics: Hospitalization and check troponin level Nitroglycerine Morphine (OS or I/V) Oxygenation Labetalol, metoprolol (Beta Blockers) Aspirin 300 mg or clopidogrel 600 mg Simvastatin, atorvastatin, rosuvastatin (Statin therapy) Ramipril Enalepril (ACE inhibitors) Situational task 7 Patient K., 72 years old, was admitted into the department of arrhythmias. Complaints. Shortness of breath with mild physical exertion, frequent dizziness, general weakness Anamnesis myocardial infarction 2 years ago. Physical examination: during the examination, the patient lost consciousness several times with the appearance of clonic seizures. Pulse: 30 beats/ min. rhythmic. BP: 140/60mmHg. Auscultation: the souds of the heart are soft, but periodically a single S1 areintensified. Auscultation of the lungs – the vesicular breathing. The liverpalpated on 3 cm belowe costal edge. Legs edema ECG: rhythem is non-sinus, regular, RR rate 30 bearts/min. PP rate – 75 beats/min P-P interval are the same, sometimes wave P is superimposed onto T wave, ventriucalr complexes duration – 0.14 sec Task: 1. Formulate a preliminary diagnosis. 2. Identify patient management tactics and provide emergency care by naming a groups of drugs and a representative according to an existing algorithm. ANSWERS: Diagnosis: Ischemic heart disease Post MI Complete AV block Morgagni Adams stroke Syndrome Tactics: Hospitalize in the ICU Pacemaker placement Atropine (subcutaneous???) CPR if sudden cardiac death Situational task 8 Patient M., 65 years old, an ambulance team was called for complaints of sudden shortness of breath, pain in the chest, an episode of loss of consciousness. This condition has developed acutely. Anamnesis: a month ago patient had a fracture of the right tibia. Immobilization was carried out by gypsum bandage. Objectively: the condition is extremely severe, shortness of breath, RR - 25 / minute, horizontal position, light diffuse cyanosis. There is no swelling of the neck veins. Pulse - 112 / min, rhythmic, weakened ("filiform"). BP 80/60 mm Hg, Auscultation of the heart: S 1 - soft, accent of S II over a. pulmonalis. Examination of the lungs and abdomen - without pathological changes. Peripheral edema is absent. ECG: sinus rhythm, heart rate 115 / min. Right axis deviation. Deep waves QIII and SI. Incomplete block of the right branch of the bundle of His. Troponin I - 1.0 ng / ml (N <0.5 ng / ml). SaO2 - 89% (N> 95%). Task: 1. Formulate a preliminary diagnosis. 2. Identify patient management tactics and provide emergency care by naming a groups of drugs and a representative according to an existing algorithm. ANSWERS: Diagnosis: Pulmonary embolism With shock Tactics: Hospitalization in the ICU Thrombolytic therapy (tenecteplase, Streptokinase) Morphine (for pain and shortness of breath Noradrenaline and Adrenaline (for shock) Oxygen therapy Papaverine, Theophylline and Drotaverine (all I/V) Heparin or amoxivarine (I/V) Situational task 9 Patient K, 25 years old, felt a significant palpitations and weakness during training in the gym. Such attacks arose a few times earlier and resolved spontaneously without treatment. Objectively: BP - 120/80 mm Hg. Heart rate - 180 beats / min., rhythmic, satisfactory filling. Auscultation of the heart – sounds are not changed, regular, tachycardia. Examination of other organs - no pathological changes. ECG: the wave P is not found, QRS - 0.08 sec, RR intervals are identical, heart rate - 180 beats / min. Task: 1. Formulate a preliminary diagnosis. 2. Identify patient management tactics and provide emergency care by naming a groups of drugs and a representative according to an existing algorithm. ANSWERS: Diagnosis: Supraventricular paroxysmal tachycardia Tactics: Vagal maneuvers If not effective: Adenosine Verapamil (Calcium channel blocker) Or Metoprolol (Beta blockers Amiodarone (anti arrhythmic) If none of the above worked: Electrical cardio version Situational task 10 Patient S., 65 years of age, who was on a hospital treatment for CAD, stable angina, complains of palpitations, severe weakness, shortness of breath. The palpitations arose suddenly 30 minutes ago at rest. Earlier such attacks arose shortly, resolved spontaneously. Objectively: patient's condition is grave. Skin of normal color. Pulse rhythmic, heart rate 180/min. BP 80/40 mm Hg. Heart sounds are rhythmic, SI is soft. Examination of the lungs and abdominal organs - no pathological changes. Peripheral edema is absent. ECG - heart rate 180 per min., wave P is absent, RR intervals are identical, QRS complex 0.14 sec. Task: 1. Formulate a preliminary diagnosis. 2. Identify patient management tactics and provide emergency care by naming a groups of drugs and a representative according to an existing algorithm. ANSWERS: Diagnosis: Ischemic heart disease coronary artery disease Stable angina Paroxysmal ventricular tachycardia Arrhythmogenic shock Tactics Electrical cardioversion Dopamine IV / Noradrenaline Amiodarone Lidocaine or Propafenone For prophylaxis: Amiodarone or Propafenone or Sotalol Situational task 11 Patient M., 28 years old. Complaints: periodic heartbeat attacks accompanied by dizziness. Patient twice lost consciousness for a few seconds. On previous ECGs the prolongation of the QT interval to 0.52 sec.was fixed. Medication treatment was not received. During the next attack on ECG: rhythm is sinus, irregular. Frequent early (R on T) ventricular extrasystoles. Frequent episodes of polymorphic (twisted, Torsade de pointes) tachycardia of varying durations. Task: 1. Formulate a preliminary diagnosis. 2. Identify patient management tactics and provide emergency care by naming a group of drugs and a representative according to an existing algorithm. ANSWERS: Diagnosis: Prolonged QT interval Ventricular extra systoles (5th class by Lown classification) Ventricular tachycardia torsade de pointes Syncope Tactics Magnesium sulfate IV Isoptin (Calcium channel blocker) or Metoprolol (beta blockers) Implantable cardioverter-defibrillator Defibrillation for thermodynamically Unstable patient Situational task 12 Patient K., aged 68, complains of palpitations, a feeling of interruptions in the work of the heart during 12 hours, shortness of breath during exercise. Anamnesis - pain behind the sternum during significant physical activity of up to 5 minutes. Patient was treated from stable angina and hypertension. Earlier such attacks arose shortly, resolved spontaneously. These palpitations arose suddenly after physical overload. Objectively. General condition of moderate severity. Skin of normal color. Pulse arrhythmic, average Heart rate 120 /min. BP - 130/70 mm Hg. Heart sounds are arrhythmic, SI is soft. Examination of the lungs and abdominal organs - no pathological changes. Peripheral edema is absent. ECG - heart rate 100-150 per min., wave P is absent, there are waves f, different intervals RR, electrical alternation of the waves R. Task: 1. Formulate a preliminary diagnosis. 2. Identify patient management tactics and provide emergency care by naming a groups of drugs and a representative according to an existing algorithm. ANSWERS: Diagnosis: Ischemic heart disease Stable angina (second functional class of angina) Myocardial sclerosis Arterial hypertension Atrial fibrillation Tactics Emergency care Amiodarone IV, Propafenone Flecainide Prophylaxis: Anticoagulants (Warfarin 3-5 mg daily) or Rivaroxaban 20mg daily Anti-arrhythmic: Amiodarone or Propafenone or Sotalol Situational task 13 Complaints cannot be collected from the patient due to lack of consciousness. It was discovered in a state of a lack of consciousness by a police officer at night in the cabin of a lorry with a running engine. The ambulance team is called. Objectively: no consciousness. Pupils react to light extremely weakly. The face is bright red. On the skin of the legs, the bladder with serous contents (5x6 cm) resembles burning of the 2nd degree. Breathing is frequent, periodically by the type of Cheyenne Stokes. Pulse 112 per minute frequent extrasystole. Blood Pressure 60/35 mm. Tones of the heart are sharply weakened. Tumor reflexes are high, uniform, sharp rigidity of muscles, bilateral symptom of Marinesco. erythrocytosis, elevated hemoglobin, hematocrit and CBC: carboxyhemoglobin levels were detected. ECG: rhythm sinus, decrease of the wave R in all leads, interval S-T displaced from the isoline in the chest, the wave T is two-phase. Task: 1. Formulate a preliminary diagnosis. 2. Identify patient management tactics and provide emergency care by naming a group of drugs and a representative according to an existing algorithm. ANSWERS: Diagnosis: Acute Carbone monoxide intoxication Severe degree Tactics Extract the patient from incident site Hospitalization Oxygen therapy Normobaric 100% oxygen Hyperbaric oxygenation Antidote therapy Acizole 2-4 time daily Situational task 14 The patient is hospitalized for community acquired pneumonia. Ceftriaxone was assigned. After the second injection of ceftriaxone, the patient's condition deteriorated suddenly. Complaints: sudden general weakness, a feeling of dyspnea, the appearance of itching. Objectively: the patient is pale, the skin is moist. BP - 60/20 mm. Hg. The pulse on the peripheral arteries is not determined. Respiratory rate 25/min. Oxygen saturation 86%. Task: 1. Formulate a preliminary diagnosis. 2. Identify patient management tactics and provide emergency care by naming a groups of drugs and a representative according to an existing algorithm. ANSWERS: Diagnosis: Anaphylactic shock Allergic reaction for Ceftriaxone Tactics: Stop using Ceftriaxone Epinephrine IV Dexamethasone Noradrenaline or Dopamine Suprastin or Tavagil IV (anti histamine) Situational task 15 Patient H., female, 27 years old, was delivered to a therapeutic department. Complaints: general weakness, fever, cough with rusty sputum. The deterioration occurred 2 days ago after overcooling. Objectively: the general condition is severe, the skin is pale. Body temperature 38.2ะก, oxygen saturation 88%, respiration rate 25 / min. Pulse is 120 bpm, rhythmic. BP 80/60 mm Hg. Auscultation: over the lower parts of lungs - vesicular breathing is weakened, fine rales and crepitation are heard. No other pathological changes were detected. Chest X-ray: infiltration of pulmonary tissue of lower parts of both sides to the level of the sixth rib. Task: 1. Formulate a preliminary diagnosis. 2. Identify patient management tactics and provide emergency care by naming drug’s groups and representatives according to a modern algorithm. ANSWERS: Diagnosis: Community acquired pneumonia Bilateral Septic shock 4th clinical group Tactics Hospitalization in the ICU Antibiotic therapy: Ceftriaxone or ceftazidime or cefepime Levofloxacin (fluroquinolone) Normal saline or lactate Rangel solution |(IV) Dopamine or noradrenaline Dexamethasone (IV) (steroids) Enoxaparin (anti coagulants) Situational task 16 Patient H. arrived at the hospital with complaints of pain in the epigastrium, dizziness, palpitations, shortness of breath, nausea, flicker of flies in front of the eyes, tinitus and a significant general weakness that developed after two- time vomiting by the “coffee ground» and black diarrhea that began around 24 hours ago. The pain decreased slightly after vomiting. The patient suffered a stomach ulcer for many years. Objective examination: the patient is in the consciousness, the skin is sharply pale, BP - 85/55 mm Hg., Pulse 100 / min, rhythmic, reduced fullness. Heart sounds are rhythmic. Breathing is vesicular. The tongue is clean and moist. The abdomen is moderately painful and tense locally in the epigastrium. Mendel`s sign is positive. Hourly diuresis: 30 ml / h. Oxygen saturation of art. blood is 95%. At rectal examination: a black liquid faeces on a glove ("melena"). FGDS: acute ulcer of small curvature of the stomach in diameter of 2 cm, with signs of ongoing bleeding. Blood tests: Indicator Indicator Output Reference values 12 RBC 2,85ั 10 /L 4.5*1012-5.5*1012/L Hemoglobin 95 g/L 120-140 g/L 9 Platelets 240*10 /L 180*109-320*109/L WBC 7,1ั 109/L 4.0*109 -9.0*109/L ESR 20 mm/h < 10 mm/h Hematocrit 25 > 30 APTT sec 20 25,4-38,4 Fibrinogen g/l 4.5 2.0-4.0 H. pylori antigen was detected by PCR In the feces. Central venous pressure – 4,0 sm Hg. Task: 1. Formulate a preliminary diagnosis. 2. Identify patient management tactics and provide emergency care by naming a groups of drugs and a representative according to an existing algorithm. ANSWERS: Diagnosis: Peptic ulcer disease Duodenal ulcer (Gastric ulcer???) Complicated by GI bleeding, moderate degree Tactics: Hospitalization in the ICU or surgical department FGDS for diagnosis and treatment purpose Hemostatics: Aminocapronic acid Transmic acid Ethamsilab sodium Fluids Normal saline PPIs Pantoprazole or Omeprazole Situational task 17 Patient B., female, 38, complains of an attack of suffocation, which arose after the inhalation of dyes. Inhalation of salbutamol in a dose of 100 micrograms did not lead to improve condition. Anamnesis: during the last 3 years - attacks of suffocation and dry cough up to 2-3 times per month, which appears due to inhalation of dyes and dust. Patient does not receive permanent treatment. Periodically she takes inhalations of salbutamol. Objectively: diffuse cyanosis, respiratory rate 32 / min, oxygen saturation 78%, pulse 110 beats /min., BP 140/80 mm Hg. Lungs auscultation - hard vesicular breathing, a large number of whistling wheezes (wheezing) over the entire surface of the lungs. The heart sounds are covered with wheezing. Other physical data – without pathological changes. Task: 1. Formulate a preliminary diagnosis. 2. Identify patient management tactics and provide emergency care by naming a group of drugs and a representative according to an existing algorithm. ANSWERS: Diagnosis: Bronchial asthma Moderate persistent Acute asthma exacerbation Tactics: Hospitalization to the ICU or pulmonology department Oxygen up to 95% Gluccocorticosteroids (IV) Dexamethasone Prednisolone SABA Salbutamol Inhaled corticosteroids Budesonide Anticoagulants Enoxaparin Theophylline Fluids (IV) 1-2L daily Situational task 18 The patient M., male, 64 years old, was examined by an ambulance team. Patient is unconscious, 8-9 points according to Glasgow Coma Scale (GCS) (Moderate, GCS 8 or 9–12). Objectively: the skin and visible mucous membranes are pale with a yellowish colour. The sclera’s are icteric. Pulse - 100 beats / min., rhythmic, BP 110/80 mm Hg. Heart auscultation - S 1 is soft. Lungs auscultation vesicular breathing. The abdomen is enlarged at the expense of free fluid. The lower edge of the liver is dense, painless, + 10 cm from the edge of the ribs' arc. Laboratory examination: a significant increase in the total bilirubin values due to direct; and significant increase in ALT and AST values. Task: 1. Formulate a preliminary diagnosis. 2. Identify patient management tactics and provide emergency care by naming a groups of drugs and a representative according to an existing algorithm. ANSWERS: Diagnosis: Liver cirrhosis of unknown etiology Class C according to child PUGH Portal hypertension 2nd degree Ascites Hepatic encephalopathy 3rd degree Tactics: Hospitalization in the ICU Diuretics Furosemide Spironolactone Lactulose Antibiotics Ciprofloxacin Rifaximin Amino acids Glutargine Ornithine Aspartate Situational task 19 Patient A., 46 years old, was admitted to the emergency department unconscious. It is known that he has diabetes mellitus for 14 years, received insulin as the treatment for his disease. The day before admission, the patient felt good. He had insulin injection in the evening before; also, it is known that he had no dinner. The patient did not wake up in the morning. Objectively: no consciousness. The skin is warm and moist. The pupils are dilated. The tone of the eyeballs is elevated. The pulse is 86 beats per minute, rhythmic, average. BP 125/80 mm Hg. The heart tones are loud. During the auscultation the breathing is vesicular. The tongue is wet and clean. The abdomen is soft. Meningeal symptoms are negative. Task: 1. Formulate a preliminary diagnosis. 2. Identify patient management tactics and provide emergency care by naming a groups of drugs and a representative according to an existing algorithm. ANSWERS: Diagnosis: DM type 1 Hypoglycemic coma Tactics: Glucose 40% (20-80ml) fast Glucagon 1mg IM Adrenaline 0,18% 1ml IM Prednisolone 3% 60mg or Hydrocortisone 100 mg IV Glucose 10% (400ml IV) Situational task 20 Patient D., 28 years old, during last month began to feel excessive thirst after stress (drank up to 6-8 liters of fluid per day), had frequent urination as well as weight loss (lost 10 kg per last month). The patient was admitted to the hospital with general weakness, nausea, vomiting with blood addition, pain in the epigastric area. Objectively. The general condition of the patient is moderate. Weight 68 kg, height 174 cm. A patient is conscious, answers the questions with delay. The skin is dry; the patient has acetone smell from the mouth. Pulse rate: 94 per minute, rhythmic. During the auscultation the breathing is vesicular. BP 105/65 mm Hg. The heart tones are muffled. The tongue is dry and red. The abdomen is soft, painful in the epigastric and right subcostal area. The liver is enlarged (+ 3 cm).The patient has no edema. Task: 1. Formulate a preliminary diagnosis. 2. Identify patient management tactics and provide emergency care by naming a groups of drugs and a representative according to an existing algorithm. ANSWERS: Diagnosis: DM type 1 Ketoacidosis first degree Tactics: Insulin 4-6 units IM every 2 hours Normal saline 500-1000 mL (IV) Potassium chloride 7.5% 20-40 ml (IV) Thiosulfate sodium 30% 10ml (IV)