Name Syed Basha Age Diagnosis Procedure Exploratory laparotomy/ Lavage/ Necrosectomy with pus drainage/ Intraperitoneal bleed/ Necrotizing Retrograde tube duodenostomy with pancreatitis inv transerse mesocolon/ serosal patch closure of duodenal 20/M Duodenal blowout/ Biliary EC fistula blowout/ Right hemicolectomy with s/p patch closure of traumatic D2-D3 end ileostomy/ Pyloric exclusion/ GJ/ injury/ FJ Jejunal resection & anastomosis/ Redo FJ ◦ RTA/ BTA on 26/1/21. Underwent emergency laparotomy by general surgery team, peripheral GH ◦ Patch closure of D2-D3 perforation & FJ ◦ Developed wound dehiscence with biliary enterocutaneous fistula. Referred to MMC & admitted under general surgery ◦ Received referral on 23/2/21. Transferred to our care ◦ FJ feeding, TPN & wound care -> Further evaluation & optimisation ◦ Developed melena & blood tinging in ECF & DT on 28/2/21. Patient was resuscitated. CT Angiogram abdomen was taken on 1/3/21, showed no active bleed but e/o transection in neck of pancreas ◦ Patient planned for emergency laparotomy. Investigations ◦ CBC - 12.6/ 12000/ 3.1 ◦ RFT – 22/ 1.0/ 138/ 4.5 ◦ LFT - 0.7/ 0.2/ 72/ 44/ 107/ 5.1/ 3.5 ◦ INR - 0.9 CT abdominal angiogram ◦ e/o herniation of bowel loops in the anterior midline to laparotomy wound ◦ e/o possible transection of head of pancreas noted, body & tail appear normal ◦ Collection with air pockets in the area of head of pancreas extending into interbowel spaces & tracking into right paracolic areas & to the midline ◦ Normal angiogram. No e/o aneurysm/ contrast extravasation Findings ◦ Dehisced wound of previous surgery filled by granulation tissue overlying bowel & omentum ◦ Dense adhesions – plastered intraperitoneal contents ◦ Head of pancreas necrosed with abscess collection ~ 5x5cm ◦ Unhealthy proximal transverse mesocolon adjacent to pancreatic necrosis. Bleeding from involved areas ◦ Duodenal blowout ◦ Multiple serosal tears in the jejunum Surgery (6/3/21) Exploratory laparotomy/ Lavage Necrosectomy with pus drainage Retrograde tube duodenostomy with serosal patch closure of duodenal blowout Right hemicolectomy with end ileostomy Pyloric exclusion/ GJ Jejunal resection & anastomosis/ Redo FJ ◦ POD-5 - biliopurulent discharge from laparotomy wound ~ 500ml/day. Managed with vacuum suction dressings & culture guided antibiotics . Gradually decreased & wound granulated ◦ Tube duodenostomy - bilious output of 1 to 1.5 L/day. Bile refeeding done ◦ Lesser sac DT initially output of 400-500ml/day, gradually reduced ◦ Patient received TPN in immediate postop period. Started on FJ feeds on POD-8 ◦ Oral liquids started on POD-18, soft diet on POD-22 ◦ Developed SAIO on POD-27. Contrast study through tube duodenostomy showed no leak. Managed conservatively ◦ Discharged 1 month postop with right DT (lesser sac) draining <50ml/day bilious output & tube duodenostomy (1 to 1.5L/day) ◦ ◦ ◦ ◦ Biopsy Pancreas - coagulative necrosis with areas of haemorrhage Small bowel mucosa - lymphocytic infiltration Appendix - chronic appendicitis