PROTEINS 1 Prepared by: Nur Fatihah Binti Din 4UPM Learning Outcomes/Objectives: State the elements in proteins. State the various structure of proteins. Explain the formation and breakdown of dipeptides and polypeptides. Explain the meanings of essential amino acids and non essential amino acids. 2 Introduction Protein are large complex organic molecules which play diverse roles in living organisms. Proteins made up of such elements as carbon, hydrogen, oxygen, nitrogen, sulphur and phosphorus. 3 Amino acid + amino acid Polypeptides + water condensation hydrolysis hydrolysis dipeptide + water dipeptides or amino acids 4 Examples Protein sources: egg, meat, milk, yoghurt and etc. 5 Protein Structures a) Primary structure b) Secondary structure - alpha-helix - beta-pleated sheets c) Tertiary structure d) Quaternary structure 6 a) Primary structure The linear sequence of amino acids in a polypeptide chain. 7 b) i) Secondary structure Alpha-helix - Three dimensional arrangement of amino acids with the polypeptide chain in a cork screw shape. iv) Beta-pleated sheet - Polypeptide chains are arranged side by side. 8 c) Tertiary structure The overall three dimensional shape of a polypeptide chain. 9 d) Quaternary structure The combination of two or more tertiary polypeptides that makes up a protein. 10 11 Amino Acids There have two types of amino acids: i) essential amino acids ii) non essential amino acids Essential amino acids are amino acids that cannot be synthesized by the body. Example: Leucine Non essential amino acids are amino acids that can be synthesized by the body. There are 11-non essential amino acids. Example: Alanine 12 Thank You 13