Philippine Journal of Natural and Social Sciences . PJNSS https://www.paressu.org/pjnss Volume 1, Issue No. 1, 2019 Online ISSN 2672-247X Antibacterial Activity of Santan Ixora coccinea Flowers Extract against Staphylococcus epidermidis and Acinetobacter baumannii Avemar Ianna D. Entendencia1* and Jocelyn G. Merrera2 1,2 Mangaldan National High School, Mangaldan, Pangasinan *Corresponding Author: avemar08@gmail.com Abstract – This research study was conducted to determine the potency of the Santan flowers to inhibit the growth of the two selected bacteria. It underwent the processes: collecting, washing, weighing, and extracting of Santan flowers, preparation of culture media, paper discs distribution to the plate of bacteria, incubating the plate of bacteria, and measuring of inhibition zone. The researcher used the Complete Randomized Design (CRD) to identify and find out its capability. The components of each treatment were as follows: Treatment 0 contains the control variable which is the Cloxacillin and Ceftazidime; Treatment 1 contains 50% concentration of Santan flowers extract; Treatment 2 contains 75% concentration of santan flowers extract; and Treatment 3 contains 100% pure concentration of santan flowers extract. Data revealed in terms of zone of inhibition (mm) that the Fcomp (1.33 and 4.33) is less than Ftab, it implies that there is no significant difference between the 3 experimental treatments there they are comparable to each other. Moreover, Tcomp value of (10.9961 and 10.0060) for Treatment 3 which yielded the highest mean value of (14.67 and 15.33) is greater than the Ttab value of (2.776), it implies that there is a significant difference between the experimental treatment and the commercial available in inhibiting the growth of Staphylococcus epidermidis and Acinetobacter baumannii. Therefore, Santan flowers extract is effective in inhibiting the growth of skin-infectious bacteria Staphylococcus epidermidis and Acinetobacter baumannii. Keywords: Santan flowers, Staphylococcus epidermidis, Acinetobacter baumannii PJNSS To cite this paper: Entendencia, A I D. & Merrera, J G. 2019. Antibacterial Activity of Santan Ixora coccinea Flowers Extract against Staphylococcus epidermidis and Acinetobacter baumannii. Philippine Journal of Natural and Social Sciences. 1(1) FULL PAPERS To request for full papers, you may contact the author thru the corresponding email. Or, you may contact the editor at editor@paressu.org. REFERENCES [1] [2] [3] [4] [5] [6] Silver, L. 2011. Challenges of antibacterial discovery. Clinical Microbiology Reviews. DOI: 10.1128/CMR.00030-10 Kern, W. 2015. Antibacterial Agents. Infections in Hematology Manaois, A. R. & J. S. Camara. 2018. In situ Biofiltration Performance of Hydro-nets as Tested in Moss in San Vicente River in San Jacinto, Pangasinan: An Environmental Assessment and Remediation. Asian Journal of Multidisiciplinary Studies. Vol. 1, No. 2. Available at asianjournal.org Wang, L, C. Hu, L. Shao. 2017. The Antimicrobial activity of nanoparticles: Present situation and prospects. International Journal of Nanomedicine. DOI: 10.2147/IJN.S121956 Levy, S. & M. Bonnie. 2004. Antibacterial resistance worldwide: Causes, challenges and responses. Nature Medicine. Jones, N. B. Ray, K. Ranjiet et al. 2008. Antibacterial activity of ZnO nanoparticles suspensions on a broad spectrum of microorganisms. FEMS Microbiology Letters. DOI: 10.111/j.1574-6968.2007.01012.x