PRESENTATION ON RATIONAL OF
USING RESPECTIVE EXCIPIENTS
1
OUTLINE
Excipient
 Suspension
 Propertise of suspension
 Types of suspension
 Classification of suspension
 Reason for preparing of suspension
 Formulation name
 Uses of magnesium suspension
 Reagent name
 Rational uses of reagent

2
EXCIPIENT

An excipient is a pharmacologically inactive
substance formulated alongside the active
pharmaceutical ingredient of a medication.
3
SUSPENSION
-Suspensions are the biphasic
liquid dosage form of
medicaments in which the
finely divided solid
particles.
-The range of solid particles in
suspensions from 0.5 to 5.0
micron.
-Suspensions are used in
orally,parentally,and also
externally.
-They are chemically stable
than solution.
4
PROPERTISE OF SUSPENSION
Heterogenous mixture
 Scatter light
 Particles are larger
than those in a
solution
 Separates into layers
over time
 Non homogeneous
 Particles can be seen
by the naked eyes

5
TYPES OF SUSPENSION

According to the particle size of the dispersed phase
,suspensions are divided into :
-Coarse suspension:which is a dispersion of particles with
a mean diameter greater than one micrometer.
-Colloidal suspension: which is a dispersion of particles
with a mean diameter less than one micrometer.
6
CLASSIFICATION OF SUSPENSION
1.Based on general class
-oral suspension
(e.g.paracetamol suspension)
- Externally applied suspension
(e.g.calamine lotion)
-parenteral suspension
(e.g.insulin zinc suspension)
2.Based on proportion of solid particles
-dilute suspension(2 to 10 % W/V solid)
e.gcortison acitate
-concebtrated suspension(50% W/V solid) e.g
zinc oxide suspension.

7
CLASSIFICATION OF SUSPENSION

Based on electrokinetic nature of solid particle
-flocculated suspension
-deflocculated suspension
8
REASON FOR PREPARING OF SUSPENSION
.
To increase
drug stability
To mask the
bitter taste of
the drug
To achive
controlled drug
release
The drug is
insoluble in the
delivery vehicle
9
FORMULATION NAME

Magnesium suspension:Magnesium hydroxide
also known as magnesium
suspension.Magnesium hydroxide is the
inorganic compound with the chemical formula
Mg(OH)2.It is a white solid with low solubility in
water .Magnesium hydroxide is a common
component of antacids such as, milk of magnesia
as well as laxatives.
10
USES OF MAGNESSIUM SUSPENSION
Constipation
 Upset stomach
 Heart burn
 Relieve indigestion
 Prevent from the ulcer

11
REAGENT NAME
Mgso4(12g)
NaON(4g)
Distilled
water
12
RATIONAL USES OF REAGENT

Magnessium sulphate uses
-constipation
-relaxing nervous system
-relieve arthritic joints.
Sodium hydroxide uses
-Chemical manufacturing
-used to makes solid soaps
Distilled water uses
-laboratory experiment
-cool in engine
13
14