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Interpreting PCV TS

12/19/2020
Interpreting PCV/TS
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Interpreting PCV/TS
Megan Brashear, CVT, VTS(ECC), explains the importance of
looking at the packed cell volume and total solids results
together, and how using both results helps get a better picture
of your patient's status and their future needs in the hospital.
Views: 94088 - Comments: 12
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Interpreting PCV/TS
Contributors
Megan Brashear
CVT VTS(ECC)
Enrolled: 07/2011
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Article
Performing a packed cell volume (PCV) and total solids is one of the easiest tests performed in a
veterinary hospital. Almost all team members can perform a PCV/TS (total solids), but how many of
them are comfortable interpreting those results? A PCV/TS can give you valuable information about
the patient’s status and help you think ahead to the next step in treatment.
The Importance of Blood
Typing
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PCV is the percentage of red blood cells in circulating blood. A decreased PCV generally means
red blood cell loss from any variety of reasons like cell destruction, blood loss, and failure of bone
marrow production. An increased PCV generally means dehydration or an abnormal increase in red
blood cell production. TS is a measurement of plasma proteins. These proteins include albumin,
globulins, and fibrinogens. A decreased TS generally means the animal is suffering from protein
loss from any variety of reasons like blood loss, PLE, PLN, or malnutrition. An increased TS usually
means dehydration but can be present in certain chronic diseases.
By looking at a hematocrit tube fresh out of the centrifuge, you can also get some idea for white
blood cell content by examining the buffy coat. The buffy coat sits between the red cell layer and
the plasma (and should not be counted as part of the PCV) and is normally 1 percent or less. A
large buffy coat can signify a large increase in WBC count. The plasma layer should also be
examined for hemolysis, lipemia, and icterus. These characteristics should be noted along with the
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PCV/TS results. Remember to look at both values together to get the entire clinical picture of your
patient, and continue to monitor throughout their hospital stay.
Video
↑PCV, ↑TS: This patient is most likely suffering from dehydration. As the water portion of blood is
decreased you will see an elevation in both the PCV and TS. Both of these values should decrease
as fluid therapy rehydrates the patient.
PCV/TS Reading
↑PCV, normal TS: This patient also may be dehydrated, but remember that the addition of fluids
will bring both values down, so there is a loss of proteins occurring. Watch this patient for the
development of hypoproteinemia and associated clinical signs (hypotension, peripheral edema) as
fluids are administered. This patient could be suffering from polycythemia, a rare condition where
the body overproduces red blood cells.
↑PCV, ↓TS : This patient could be suffering from dehydration and a profound protein loss. More
commonly, you may see this with a recent trauma. This patient may be suffering from acute blood
loss and splenic contraction has temporarily increased the PCV, but the low TS points you towards
blood loss. In a trauma patient where you expect blood loss it is important to recheck the PCV and
TS after starting treatment.
Normal PCV, ↑TS: This is a common scenario with CKD cats. This patient is most likely suffering
from anemia and dehydration. The normal PCV may fool you into thinking this animal is okay, but
as you rehydrate remember that both numbers will drop leaving you with an anemia to treat.
Views: 22,298 Comments: 15
Video
Blood Collection Tubes
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Normal PCV, normal TS: Normal is good, right? Be sure to match the results to the patient. If this
patient sustained recent trauma there may be blood loss that isn’t apparent on blood work yet. If the
results are different than what you expected, then recheck the PCV/TS as you begin treatment.
Normal PCV, ↓TS: This patient is most likely suffering from a protein losing disease (PLN, PLE),
chronic diarrhea, or certain liver and kidney diseases. Be prepared for clinical signs of
hypoproteinemia (hypotension, peripheral edema) and their treatment.
↓PCV, ↑TS: The elevated TS most often points to dehydration, and remembering that the addition of
fluids will further drop the PCV, this patient is anemic and needs close monitoring of the PCV and
most likely the addition of blood products.
↓PCV, normal TS: This patient is suffering from RBC destruction lack of production. In blood loss
we expect to see a decrease in the TS as well. With just the red cells decreased be on the lookout
for IMHA.
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↓PCV, ↓TS: This patient is suffering from whole blood loss and needs to be monitored very closely.
Blood products should be considered in treating this patient.
Armed with this information, you now know a great deal about your patient just by looking at the
PCV/TS. By using critical thinking skills and knowledge of the treatment plan for these patients you
can prepare for their future needs.
Video
Clotting Tests
Views: 9,220 Comments: 1
Packed Cell Volume %
Total Solids g/dl
Rule Out
↑
↑
dehydration
↑
normal
dehydration, protein loss
↑
↓
acute blood loss
normal
↑
anemia, dehydration
normal
normal
normal
normal
↓
protein loss
↓
↑
anemia, dehydration
↓
normal
RBC destructive disease
↓
↓
whole blood loss
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Comments
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Interpreting PCV/TS
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Megan Barclay
Thu, 05/30/2013 - 21:11
If acute blood loss occurs, how long until it has a significant effect on the PCV/TP
results?
The initial pcv immediately after a bleed is not always an accurate reading?
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Megan Brashear
Fri, 05/31/2013 - 03:50
That's a GREAT question Megan. I don't have an exact time frame of when you'll
see the effects of whole blood loss, but the spleen does have a reserve of blood just
waiting for a disaster. After a trauma and/or acute blood loss, the spleen will send
that reserve into circulation and when that animal first presents they may have a
normal PCV/TS. It is ALWAYS a good idea to recheck that number about 30-60
minutes after presentation, as IV fluids will cause dilution of the PCV and continued
loss will sometimes cause a dramatic drop. If you see clinical signs of anemia before
that 30-60 minutes (tachycardia, tachypnea, not responding to fluid resuscitation,
etc) by all means check again and get that blood transfusion ready!
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Megan Barclay
Fri, 05/31/2013 - 09:48
Thank you Megan, that's very helpful.
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Gerson Escobar
Sat, 07/13/2013 - 01:39
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Interpreting PCV/TS
sorry Megan, but, What is the meaning of "PLE" and "PLN" ?
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Megan Brashear
Mon, 07/15/2013 - 04:01
Gerson, PLE is Protein Losing Enteropathy (losing abnormal amounts of protein
through the GI tract), and PLN is Protein Losing Nephropathy (losing abnormal
amounts of protein through the urine). Good question!
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Alana Twomey
Fri, 09/20/2013 - 21:22
What is the difference between TS and TP?
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Megan Brashear
Thu, 09/26/2013 - 04:12
Alana, you bring up a great point, I am guilty of using TS and/or TP as the same
thing, which they are not. TP is a measurement of only the proteins in plasma, not
looking at non-protein solids also present (think triglycerides - then think about
lipemic patients and what you get on the refractomoeter). TS is taking into account
all of the solids in plasma. Our refractometers are calibrated to read TP and
automatically subtract about 2.0g/dl for the rest of the solids. Thankfully we all
speak the same language and know what you mean when you say PCV/TS, but
they are different.
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Katrina Luddy
Sun, 04/21/2019 - 08:20
https://www.atdove.org/article/interpreting-pcv-ts
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Thank you! So helpful, loved the little chart here at the end!!
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Samantha Bliven
Wed, 04/22/2020 - 19:15
What are normal PCV and TS values? Maybe I missed it, but I didn't see any values
listed in the article.
Thank you,
Samantha Bliven
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Kelsey Reinauer
Wed, 05/06/2020 - 16:07
Hi Samantha,
Normal PCV values for dogs are 35-55% and cats 30-45%. Normal TS values for
dogs are 5.2-8.2g/dL and for cats 5.7-8.9 g/dL.
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Rachel Olson
Mon, 08/17/2020 - 14:11
Was looking for this info too. Thanks!
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Samantha Bliven
Mon, 08/24/2020 - 15:45
Thank you!
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