Head, Shoulders, Knees and Toes The Skeletal System Outline • Intro • Bone Structure • Bone Development • Bone Function • Skeletal Organization – Axial and appendicular skeleton • Joints • Joint Movements Bone is ALIVE May appear dead…but is actually composed of very active tissues Functions include: 1. Muscle attachment 2. Protection and support 3. Blood cell production 4. Storage of minerals General Bone Structure Bones differ greatly in size and shape, but they have a lot in common too! Microscopic Structure Microscopic Structure Microscopic Structure Microscopic Structure Microscopic Structure • Osteocytes (bone cells) are located in lacunae (spaces) that lie in concentric circles, called lamella, around osteonic canals • Osteocytes pass nutrients and gases in the matrix through canaliculi • What’s between the cells? – Collagen (structural protein), inorganic salts (eg. Calcium Phosphate) “osteogenic potency” “osteogenic potency” Section through head of femur Compact bone Spongy bone Yellow Marrow Red Marrow Important cells of bone tissue – Osteoblasts – cells that deposit bone tissue around themselves; contain receptors for hormones that regulate bone growth – Osteocytes – former osteoblasts that have become trapped in the bony matrix they just secreted; stop depositing bone but still involved in cellular activities in their local area – Osteoclasts – cells that can degrade bone back into its mineral components; these mineral ions are used in the body for muscle contraction, nerve transmission, energy transfer reactions, etc. Bone Development and Growth • Bones form by replacing connective tissue in the fetus • Some form within sheet-like layers of connective tissue (intramembranous bones), while others replace masses of cartilage (endochondral bones) Intramembranous Ossification The flat bones of the skull form as intramembranous bones that develop from layers of connective tissue Endochondral Ossification First develop as hyaline cartilage models in the fetus, which is later replaced with bone Most bones in the body form this way Growth in LENGTH Endochondral Ossification Growth in diameter? Osteoblasts of the periosteum lay down new compact bone while osteoclasts resorb bone in the medullary cavity Homeostasis of Bone Tissue Depending on the body’s needs, osteoclasts tear down and osteoblasts build bone Under Hormonal control: 1. Calcitonin – released when supply of calcium in blood is plentiful or high; calcium deposited in bone (osteoblasts) 2. Parathyroid Hormone – released when blood supply of calcium is low; bone resorbed into bloodstream (osteoclasts) Bone Functions 1. Muscle attachment • Movement of the body • Bones act as levers 2. Protection and support 3. Blood cell production • Red blood cells, white blood cells, and platelets are formed in the RED MARROW • RM found in spongy bone of skull, ribs, sternum, clavicles, vertebrae, and pelvis • Fat is stored in the YELLOW MARROW; found in most bones 4. Storage of minerals • Store calcium, but also magnesium, sodium, potassium, and carbonate ions • Released or stored according to body needs Skeletal Organization Axial Appendicular Major Bones of the Human Skeleton Orange = Axial Skeleton Yellow = Apendicular Skeleton Axial Skeleton Skull 1. Cranium • Encloses and protects the brain • Attachment point for muscles for chewing and head movement • Air-filled sinuses reduce its weight 2. Facial skeleton • 13 immovable facial bones and mandible • Attachment point for muscles – facial expressions, mastication CopyrightThe McGraw-Hill Companies, Inc. Permission required for reproduction or display. CopyrightThe McGraw-Hill Companies, Inc. Permission required for reproduction or display. CopyrightThe McGraw-Hill Companies, Inc. Permission required for reproduction or display. The Vertebral Column 1. Cervical vertebrae • 7 bones, comprise the neck and support the head • Atlas – 1st vertebra, supports head • Axis – 2nd vertebra, has dens that pivots within the atlas 2. Thoracic vertebrae • 12 bones, articulate with the ribs 3. Lumbar (see later slides) 4. Sacrum (see later slides) 3. Lumbar vertebrae - 5 massive bones support the majority of the body weight 4. Sacrum – triangular structure at base of vertebral column; composed of 5 fused vertebrae 5. Coccyx – lowermost portion; four fused vertebrae The Thoracic Cage • Includes the ribs, thoracic vertebrae, sternum, and costal cartilages • Breathing, support and protection Appendicular Skeleton The Pectoral Girdle • Forms incomplete ring that supports the upper limbs • Made of two clavicles and two scapulae The Upper Limb • Bones of the upper limb form the framework for the arm, forearm, and hand CopyrightThe McGraw-Hill Companies, Inc. Permission required for reproduction or display. The Pelvic Girdle • Composed of the two coxal bones and the sacrum • Protection of lower body organs, supports weight on lower limbs The Lower Limb • Bones of the upper limb form the framework for the thigh, lower leg, and foot Joints 1. Fibrous • Joint composed of dense connective tissue • No movement, or only very little movement • Ex: Sutures in the skull 2. Cartilaginous • Joint composed of hyaline cartilage or fibrocartilage • Ex: Intervertebral disks, pubic symphysis 3. Synovial • Most joints are synovial • Articular ends covered in hyaline cartilage • Joint capsule: connective tissue, synovial membrane, and synovial fluid • Ex: knee, hip, shoulder, elbow 5 Types of synovial Joints Bone Fractures pg. 136 Bone Healing