Corpus Christi College
Year 12 Human Biology
Semester 2
Task Type:
Extended Response
Content:
Comparative Biochemical Evidence
Task Weighting:
4%
Task Description: Task 11: Extended Response
Possible Marks
Total 46
36
Percentage
100%
Your Mark
Student Name:
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Date:
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Teacher:
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12
1
Answer the following questions in the space provided.
1. Describe these two comparative studies –
 Proteins
 Nuclear DNA
and explain how they are used to show evidence for evolution.
(10 marks)
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2
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3
2. Describe what a ubiquitous protein is and how they may provide evidence of
evolutionary relationships. In your answer, you should make reference to a
specific example.
(5 marks)
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4
3. Mitochondrial DNA (mtDNA) samples have been extracted from the fossils of Homo
neanderthalensis people and compared with those of modern humans Homo
sapiens. Data shows the two are very close and was used to help decide if speciation
had actually taken place. Describe how the study of mtDNA can be used to support
the theory of evolution and the relationship between Homo neanderthalensis and
modern humans.
(5 marks)
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5
4. Discuss how bioinformatics is used with comparative genomics to determine
evolutionary relationships.
(7 marks)
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6
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7
5. Using only the data from this section of the haemoglobin molecule below,
rank the five other species in order, from the one closest to humans to the
one most distant.
6. What are endogenous retroviruses?
7. How do retroviruses become endogenous?
(1 mark)
(1 mark)
(3 marks)
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8
8. Using the amino acid sequences below, showing sequence numbers 87-116,
fill in the table, and state the following:
(5 marks)

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The total number of amino acid differences between the given organisms.
The amino acid sequence number/numbers where these occur.
END OF ASSESSMENT
9