Contents 1. Cells .................................................................. 1 2. Tissue and Muscle ........................................... 3 3. Body Fluids ....................................................... 8 4. Blood ............................................................... 11 5. Digestive System ........................................... 21 6. Kidney ............................................................. 32 7. Endocrines and Reproduction ...................... 46 8. Cardiovascular System ................................. 54 9. Respiration ..................................................... 69 10. Nervous System: Special Senses ................. 78 Cell 1 CHAPTER 1 Cell 1. Each chromosome is made up of supporting protein like: A. DNA B. RNA C. MRNA D. ALL 2. The large constituent of a cell is: A. Nucleus B. Nucleolus C. Endoplasmic reticulum D. Mitochondria 3. Power-generating unit of the cell is: A. Nucleus B. Lysosomes C. Ribosomes D. Mitochondria 4. Nucleus of most cells contain: A. A neucleolus B. A patch work of granules rich in ribonucleic acid (RNA) C. Chromatin threads which carry genes D. All the above 1 A 2 C 3 D 4 D 2 MCQS in Physiology 5. Golgi complex is a collection of: A. Membranous tubules and vesicles B. Granules C. Rods D. Reticular fibres 5 A Tissue and Muscle 3 CHAPTER 2 Tissue and Muscle 1. The matrix of connective tissue consists mainly of: A. Phospholipids B. Hyaluronic acid C. Amioacids D. Collagen 2. A sarcomere is a unit between two successive: A. I Zones B. Z Lines C. A Zones D. M Lines 3. Latent period is prolonged in all of the following except: A. Increase of temperature B. Decrease of temperature C. Acidosis D. Fatigue 1 D 2 B 3 A 4 MCQS in Physiology 4. Which of these is accompanied by shortening of muscle? A. Isotonic contraction B. Isometric contraction 5. In which of these tissues mitosis is not seen during adult life? A. Epithelium B. Adipose tissue C. Neural tissue D. Cartilage 6. Which of these ions is MOST important for beneficial effect of successive stimuli? A. Sodium B. Potassium C. Calcium D. Hydrogen 7. Which of these are phagocytic? A. Macrophages B. Fibroblasts C. Osteoblasts D. None of the above 8. The chemicals found in connective tissue are: A. Chondroitin B. Keratin C. Both D. Neither 9. Stratified squamous epithelium is found in: A. Ureter B. Urinary bladder C. Skin D. None of the above 10. Which of these cannot be tetanised ? A. Skeletal muscle B. Smooth muscle C. Cardiac muscle 4 A 5 C 6 C 7 A 8 A 9 C 10 C Tissue and Muscle 5 11. Haversian canals are found in: A. Liver B. Spleen C. Lymph node D. Bone 12. The principal cell of connective tissue is: A. The adipocyte B. The hyalocyte C. The fibroblast D. The osteoblast 13. The immediate source of high energy phosphates is: A. Creatine phosphate B. Guanosine phosphate C. Carbamyl phosphate D. Glycerophosphate 14. In skeletal muscles, all or none principle applies to: A. Single muscle fibre B. Motor unit C. Fasciculus D. Muscle as a whole 15. Glial tissue is found in the: A. Heart B. Brain C. Liver D. Kidney 16. Bone reabsorption is due to the activity of: A. Osteoblasts B. Osteclasts C. Osteocytes D. Monocytes 17. Which of these is concerned with oxidation ? A. Mitochondria B. Golgi vesicles C. Ribosomes D. All of the above 11 D 12 C 13 A 14 A 15 B 16 B 17 A 6 MCQS in Physiology 18. Epithelium of the urinary bladder is: A. Columar B. Cuboidal C. Squamous D. Transitional 19. Which of these is NOT a contractile protein of the muscle ? A. Actin B. Fibrin C. Myosin D. Troponins 20. Alveolar epithelium is: A. Columnar B. Squamous C. Neither 23. Chronaxie is presentation time of: A. Rheobase B. Twice rheobase C. Half the rheobase 24. Which of these can block skeletal neuromuscular transmission ? A. Curare B. Atropine C. Nicotine D. Pilocarpine 25. Cilia are projections of: A. Smooth muscle fibres B. Nerve fibres C. Epithelial cells D. Fibroblasts 26. Jogging is an example of: A. Isotonic contraction B. Isometric contraction 18 D 19 B 20 A 23 B 24 A 25 C 26 B Tissue and Muscle 7 27. Distinguishing feature of cardiac muscle is: A. Presence of glycogen B. Syncitium C. Absence of sarcoplasmic triad 28. Ciliare are seen in: A. Bronchi B. Bronchiloes C. Both D. Neither 27 B 28 C 8 MCQS in Physiology CHAPTER 3 Body Fluids 1 . Internal environment of the cell is determined by: A . Intracellular fluid B. Tissue fluid C . Plasma D . Blood 2 . Components of ECF are: A . Interstitial fluid B. Blood C . Hymph and serous fluids D . All of the above 3 . Intracellular fluid water content is: A . 2/3 rds of the total body water B. 1/3 rd of the total body water C . 1/5 th of the total body water D . 1/8 th of the total body water 4 . Plasma volume can be measured by using: A . Evans blue (T1824) B. Sucrose C . Methelene blue D . Cresyl blue 1 B 2 D 3 A 4 A Body Fluids 9 5 . Commonly used Radioactive element in measuring red cell volume is: A . 51 cr B. 48 Ti C . 238 U D . 232 Th 6 . Transcellular fluid comprises: A . Cerebrospinal fluid B. Aqueous and vitreous humor C . Digest time juices, serous and synovial fluids D . All the above 7 . Proteins enter the cells by the process of: A . Endocytosis B. Active transport C . Simple diffusion D . Facilitated diffusion 8 . Total amount of body water in an average wt, of 70 kgs: A . 40 lits B. 30 lits C . 20 lits D . 10 lits 9 . Insensible water loss is: A . By urine B. By faeces C . By Sweat D . By diffusion through skin 10. Intracellular fluid A . 25 lits of fluid B. 40 lits of fluid C . 15 lits of fluid D . 50 lits of fluid compartment comprises of: 11. Extracellular fluid compartment is composed of: A . 25 lits B. 40 lits C . 15 lits D . 50 lits 5 A 6 D 7 A 8 A 9 D 10 A 11 C 10 MCQS in Physiology 12. Extracellular fluid contains: A . Large quantities of Na+, Cl¯ B. Large quantities of HCO3 C . Small quantities of K+, Ca+, Mg+,PO4¯, SO4¯ D . All are correct 13. Intracellular fluid contains: A . Small quantities of Na+, Cl¯ B. Large quantities of K+, PO4¯ C . Moderate quantities of Mg+, SO4¯ D . All are correct 14. Hypotonic solution is: A . Less than 0.9% of Nacl solution B. More than 0.9% of Nacl solution C . Same as that 0.9% of Nacl solution D . 1.0% Nacl solution 15. Hypertonic solution is: A . Less than 0.9% of Nacl solution B. More than 0.9% of Nacl solution C . Same as that 0.9% of Nacl solution D . 0.8% Nacl solution 16. When hypertonic solution is added to ECF: A . Osmolarity increases B. Osmosis of water occurs from cell to ECF C . Cell shrinks D . All the above 17. When hypotonic solution is added to ECF: A . Osmolarity of ECF decreases B. Entry of water occurs from ECF in to cell C . Cell swells D . All the above 12 D 13 D 14 A 15 B 16 D 17 D Blood 11 CHAPTER 4 Blood 1 . The normal volume of blood of a man weighing 70 kgs is: A . 2 lit B. 4.5 lit C . 5.6 1it D . 6.0 lit 2 . In regulation of osmotic pressure the major role is played by: A . WBC B. HB C . RBC D . Albumin 3 . The specific gravity of the plasma is due to: A . The protein concentration B. The ionic concentration C . The water content present in it 4 . The RBCs are bound by: A . Epithelium B. Elastic membrane C . Protein layer D . Non-elastic membrane 1 C 2 D 3 A 4 B 12 MCQS in Physiology 5 . In a two-month old foetus the RBC are produced in: A . Bone marrow B. Liver C . Spleen D . Yolk sac 6 . Iron is transported in the blood as: A . Iron oxidate B. Transferrin C . Haemoglobin D . Siderin 7 . Iron is stored in liver in the form of: A . Ferritin B. Ferrous C . Ferric oxide D . Ferric sulphate 8 . Major buffer in blood is: A . Haemoglobin B. Haemosiderin C . Platelets D . Haemopoitin 9 . Lack of intrinsic factor causes: A . Megaloblastic anaemia B. Pernicious anaemia C . Aplastic anaemia D . Thalassaemia 10. Haem contains a pure pigment known as: A . Porphyrin B. Carotin C . Chlorophil D . Bile 11. Rericulocytes are increased in the following conditions: A . Before haemorrhage B. After haemorrhage C . Lack of vitamin D . Lack of proteins 5 D 6 B 7 A 8 A 9 B 10 A 11 B Blood 13 12. Synthesis of Hb occurs in the: A . Mitochondria B. Gogi apparatus C . Nucleus D . Food vacuoles 13. The concentration of hb in each RBC per deciliter is: A . 36 picograms B. 32 picograms C . 33 picogram D . 30 picogram 14. The postpituitary hormone that is responsible for water balance is: A . Vasopressin B. Oxytocin C . Prothrombin D . None 15. The hormone which regulates the water balance through electrolytes is: A . Aldosterone B. Vasopressin C . Oxytocin D . Progesterone 16. The secretion of aldosterone is controlled by: A . Angiotensin II B. Low serum Na+ C . High serum K+ D . All 17. Platelets play an important role in the: A . Haemolysis B. Haemopoiesis C . Haemostasis D . Homeostasis 18. The normal life span of platelets is: A . 8-10 days B. 8-10 days C . 8-10 weeks D . 8-10 months 12 A 13 C 14 A 15 A 16 A 17 C 18 A 14 MCQS in Physiology 19. The anticoagulants which act both in vivo and vitro are: A . Heparin B. Oxalate C . Citrate D . All 20. Failure of maturation of RBC is due to poor absorption of: A . Folic acid B. Vit. B12 C . A and B D . Zinc 21. Red bone marrow is absent in: A . Pernicious anaemia B. Sickle cell anaemia C . Aplastic anaemia D . Megaloblastic anaemia 22. In A. B. C. D. Polycythemia the blood shows: Increased volume Increased viscosity Decreased velocity All the above 23. In A. B. C. D. anaemia the blood shows: Increased viscosity Increased resistance Decreased viscosity Decreased velocity 24. Symptoms of erythroblastosis foetalis is: A . Anaemia B. Jaundice C . Oedema D . All 25. Cyanosis is caused when the reduced Hb concentration of blood in capillaries is more than: A . 3mg/dl B. 5mg/dl C . 10mg/dl D . 12mg/dl 19 D 20 C 21 C 22 D 23 C 24 D 25 B Blood 15 26. In A. B. C. D. pernicious anaemia the colour index is: More than one Less than one Equal to one All 27. Pernicious anaemia is: A . Microcytic hypochromica anaemia B. Microcytic hyperchromic anaemia C . Macrocytic hyperchromic anaemia D . Macrocytic hypochromic anaemia 28. The metal which causes haemolysis is: A . Lead B. Copper C . Iron D . Chromium 29. Sickle cell anaemia is commonly seen in: A . India B. America C . Europe D . Africa 30. Total gastrectomy will lead to: A . Aplastic anaemia B. Megaloblastic anaemia C . Sickle cell anaemia D . Thalassemia 31. Secondary polycythemia results due to more supply of O 2: B. More supply of CO2 C . Less supply of O2 D . Less supply of CO2 32. Physiological polycythemia is seen in persons living at: A . High altitudes B. Low altitudes C . Planes D . Mines 26 A 27 C 28 A 29 D 30 31 C 32 A 16 MCQS in Physiology 33. A person having pinkish tint to the skin may be suffering from: A . Anaemia B. Eosinophillia C . Leukaemia D . Polycythaemia 34. The viscosity of blood depends on concentration of: A . RBC B. WBC C . Platelets D . None 35. Partial cell antibodies are detected in: A . Aplastic anaemia B. Thalassaemia C . Pernicious anaemia D . Sickle cell anaemia 36. The major constituent of plasma protein is: A . α - globulin B. Albumin C . β-globulin D . Fibrinogen 37. The albumin, globulin ratio is: A . 2:1 B. 1:1.5 C . 1:2 D . 1:1 38. In A. B. C. D. liver disease albumin globulin ratio is: Increases Decreases Reverted Not altered 39. Antibodies belong to the class: A . Gamma globulins B. β - globulins C . Fibrinogen D . α - globulin 33 D 34 A 35 C 36 B 37 A 38 C 39 A Blood 17 40. The vitamin that is necessary for the formation of prothrombin is: A . Vit. E B. Vit C C . Vit K D . Vit D 41. The protein exerting maximum smotic effect is: A . Albumin B. Globulin C . Fibrinogen D . Prothrombin 42. Gamma globulin is synthesized by: A . Liver B. Plasma cells C . Reticuloendothelial D . Kidney 43. The degraded albumin is eliminated by: A . Blood B. Kidney C . Spleen D . Lungs 44. The colloid osmotic pressure exerted by plasma proteins is called: A . Oncotic pressure B. Blood pressure C . Both D . None 45. When fully saturated 1 gm of Hb combines with: A . 1.15 ml of oxygen B. 2.16 ml of oxygen C . 1.30 ml of oxygen D . 1.34 ml of oxygen 40 C 41 A 42 B 43 B 44 A 45 D 18 MCQS in Physiology 46. The haemoglobin, Oxyhaemoglobin buffer system is an effective method for buffering: A . Acetic acid B. Amino acid C . Carbonic acid D . Hydrochloric acid 47. The relative proportion Hb in red cell is shown by: A . Colour index B. MCV C . MCHC D . PCV 48. The synthesis of Hb begins in the: A . Basophil erythroblast B. Ortho erythroblast C . Chromophil erythroblast D . Reticulocyte 49. Blood group in human beings is classified by: A . Landsteiner B. Vernier C . Boyels D . Lewis 50. It is said to be agglutinated when the: A . RBCs are seperated B. RBCs are clumped together C . WBCs are clumped together D . Platelets are clumped together 51. The group which has no agglutinogen is: A . A group B. B group C . O group D . AB group 52. The chromosome responsible for the inheritance of blood group ABO is: A . 10th pair B. 11th pair C . 9th pair D . 8th pair 46 C 47 A 48 C 49 A 50 B 51 C 52 A Blood 19 53. Antigen of blood group is present: A . Inside the RBC B. In the plasma C . On the surface of RBC D . On the surface of WBC 54. In A. B. C. D. tissue transplantation the rejection is because of: T.lymphocytes B.lymphocytes Neutrophils Basophils 55. The commonest Rh antigen is: A. C B. E C. D D. D 56. Prothrombin times in the plasma is prolonged by the administration of: A . Vit K B. Calcium glycinate C . Dicumerol D . Folic acid 57. Substance which causes platelets activation is: A . Fibrinogen B. Damaged collagen C . Prothrombin D . Prothrombin activation 58. Edema is caused by the deficiency of: A . Albumin B. α-globulin C . β-globulin D . Fibrinogen 59. The main function of globulin is: A . Maintenance of osmotic pressure B. Defence mechanism C . Water balance D . Iron balance 53 C 54 A 55 C 56 C 57 B 58 A 59 B 20 MCQS in Physiology 60. During the immunization against infective diseases the fraction of plasma which increases: A . Albumin B. Globulin C . Fibrinogen D . Prothrombin 61. During starvation plasma proteins are formed from: A . Tissue proteins B. Blood C . Liver D . Kidney 62. Osmotic pressure exerted by plasma proteins, influence the exchange of: A . Gasses between blood and tissues B. Fluid between blood and tissues C . Nutritive materials D . Diapedisis 63. In plasmapheresis is repeated daily the amount of plasma protein in blood: A . Will increase B. Will decrease C . Remains the same D . Will become zero 60 B 61 A 62 B 63 B Digestive System 21 CHAPTER 5 Digestive System 1 . Secretion from the parotid gland is: A . Thin and watery B. Thick viscous C . Acidic in nature D . None of the above 2 . Functions of saliva include all except: A . It aids speech B. Prevents dental caries C . Helps mastication D . Helps in digestion of proteins 3 . Which of the following substances salivary secretion increases: A . Sodium B. Potassium C . Calcium D . Bicarbonate 1 A 2 D 3 D increases as the 22 MCQS in Physiology 4 . The Major stimulus for primary peristalsis esophagus is: A . Presence of food in the esophagus B. Swallowing C . Rgurgitation of food from stomach D . Closing of the upper oesophageal sphincter in the 5 . Brain stem co-ordination is necessary for the following Except: A . Swallowing B. Primary oesophageal peristalsis C . Gastric emptying D . Vomiting 6 . Gastric Parietal cells secrete: A . Gastrin B. Motilin C . Cholecysto kilin D . Intrinsic factor 7 . Secretion of pepsin is influenced by the following except: A . Vagal stimulation B. Insulin C . Food in the stomach presence of protein D . Secretin 8 . Acid secretion in the cephalic phase is stimulated by: A . Histamine B. Gastrine C . Acetyl choline D . Secretin 9 . The effective inhibitor of gastric secretion is: A . Entero gastrone B. Somatostatin C . Gluca Gon D . Cholecysto Kinin 10. Stimulus for receptive relaxation of the stomach is: A . Food in the stomach B. Food in the intestine C . Secretin D . Cholecysto Kinin 4 B 5 C 6 D 7 D 8 C 9 B 10 A Digestive System 23 11. Amylase is secreted by: A . Hepatocytes B. Acinar cells of pancreas C . Parietal cells of stomach D . Goblet cells 12. Total removal of pancreas can cause: A . Diabetes mellitus B. Increase in faecal fat content C . Increase in faecal nitrogen content D . All of the above 13. Secretion of gastrin is inhibited by: A . HCL in gastric lumen B. Distension of gastric lumen C . Plasma Epinephrine D . All of the above 14. Presence of the fat in the duodenum: A . Inhibits secretion of secretin B. Stimulates CCK - Pz secretion C . Stimulates gall bladder contraction D . All of the above 15. Important function of the Brunners gland secretion is: A . To protect the deodenal mucosa from ulceration B. To provide water and electrolyte C . To secrete Gitract hormones D . All of the above 16. Saliva is: A . Acidic B. Alkaline C . Neutral 17. Ptyalin acts on: A . All carbohydrates B. Proteins C . Cooked starch 11 B 12 D 13 A 14 D 15 A 16 A 17 C 24 MCQS in Physiology 18. Bacterecidal action of saliva is due to: A . Hyaluronidase B. Amylase C . Lysozymes D . Peptidase 19. Saliva secreted from parotid gland is mainly: A . Serous B. Mucous C . Mixed 20. The involuntary phase of deglutition is: A . Oral B. Pharyngeal C . Oesophageal 21. Achalasiais: A . Failure of stomach to relax B. Failure of upper oesophagus to relax C . Failure of cardia to relax D . Failure of pyloric sphincter to relax 22. Parietal cells produce: A . Hcl B. Pepsin C . Gastrin D . Intrinsic factor E . A and D 23. PH A. B. C. D. of gastric juice is approximately: 5-6 4-5 2-3 7-8 24. Average gastric emptying time for a mixed meal is: A . 3.5-5 hours B. 1-2 hours C . 2-3 hours D . 7-8 hours 18 C 19 A 20 C 21 C 22 E 23 C 24 A Digestive System 25 25. Which of the following has the maximum emptying time? A . Proteins B. Carbohydrates C . Fats D . Water 26. Gastrin in produced by cells in the: A . First part of the duodenum B. Antrum C . Fundus of stomach D . Cardia of stomach 27. Actions of gastrin include all the following except: A . Stimulation of acid secretion B. Inhibition of gastric enzymes C . Increasing time of sphincters of stomach D . Contraction of gall bladder 28. Histamine stimulation of gastric acid is mediated by: A . H1 receptors B. H2 receptors C . Both D . Neither 29. Cephalic phase of gastric secretion is mediated by: A . Sympathetic nerves B. Phrenic nerves C . Vagus 30. The alkalinity of the pancreatic juice is due to: A . OH¯ B. Cl¯ C . SO4¯ D . HCO3¯ 31. Normal level of total serum bilirubin is: A . 0.3-0.5 mg/100 ml B. 2-5mg/100ml C . 0.2-0.8 mg/100 ml D . 3-6mg/100ml 25 C 26 B 27 B 28 B 29 C 30 D 31 C 26 MCQS in Physiology 32. Failure of bilirubin conjugation is seen in: A . Dubin Johnson syndrome B. Rotor syndrome C . Gigglar - Najjar syndrome D . Gilberts syndrome 33. In A. B. C. haemolytic jaundice bilirubin in the blood is mostly: Conjugated state Unconjugated state Oxidised state 34. Vitamin B12 is mostly adsorbed at the: A . Duodenum B. Jejunum C . Ileum 35. Trypsonogen is activated by: A . HCL B. Streptokinase C . Enterokinase D . Pepsin 36. The principal action of secretin is to stimulate: A . Pancreatic enzyme secretion B. Pancreatic bicarbonate secretion C . Absorption of carbohydrate D . Gall bladder contraction 37. Glucose is absorbed by: A . Passive diffusion B. Osmosis C . Carrier - mediated transport D . Pinocytesis 38. Lacteals transport all the following except: A . Trigly cerides B. Cholesterol esters C . Short chain fatty acids 32 A 33 B 34 C 35 C 36 B 37 C 38 C Digestive System 27 39. Iron is better absorbed in the: A . Oxidised state B. Reduced state 40. Obstructive jaundice is characterised following except: A . Raised plasma bilirubin B. Raised serum alkaline phosphatase C . Bile pigments in the urine D . Haemolysis by all of the 41. Secretomotor nerves to the alimentary tract are: A . Parasympathetic B. Sympathetic 42. Colonic mucosa A . Magnesium B. Potassium C . Sodium D . Calcium secretes: 43. Defaecation reflex is: A . Parasympathetic B. Sympathetic 44. Which of the following does not belong to the group? A . Secretion B. Cholecystokinin C . Pankreozymin D . Enterokinase 45. The function of bile salts include all of the following except: A . Fat digestion B. Fat absorption C . Absorption of water soluble vitamins D . Absorption of fat soluble vitamins 46. Tone of the gastro esophageal sphincter is decreased by: A . Coffee B. Gastrin C . Secretin D . HCL 39 B 46 D 40 D 41 A 42 B 43 A 44 D 45 C 28 MCQS in Physiology 47. Gastrin is produced from other than antrum, from: A . The intestinal Villi B. Appendix C . D. cells of islets of Langerhans D . Kupffer cells of liver 48. The cells of the intestinal mucosal wall include all of the following except: A . Enterochremaffin cells B. Cryptic cells C . Oxyntic cells D . Paneth cells 49. Difference between vomiting of central and of peripheral origin is: A . The time of occurrence B. The frequency C . Presence of marked nausea 50. Parietal cells produce: A . Hcl B. Pepsin C . Gastrin D . Intrinsic factor E . A and D 51. Which of the following movements is NOT seen in normal individuals in the intestine? A . Segmentation contraction B. Peristaltic waves C . Peristaltic rush D . Movements of villi 52. Malabsorption syndrome occurs when: A . Partial gastrectomy B. Total gastrectomy is indicated C . Twenty per cent of small intestine is resected D . More then 50% of small intestine is resected 47 C 48 C 49 C 50 C 51 C 52 D Digestive System 29 53. The following are true of saliva except: A . Salivary digestion is completed in the stomach B. Salivary amylase acts on cooked starch only C . The enzyme is effective only in an alkaline pH D . Saliva contains lysozymes 54. The following are true of lower oesophegeal sphiretor except: A . It is a true anatomic sphirector B. It relaxes when the oesophegeal peristalus reaches the cardia C . Both D . Neither 55. Achalesia cardia is due to degeneration of: A . Musculari Mucodal B. Meissners plexus C . Auerbeachs plexas D . None of the above 56. Parietal cells produce all these except: A . Intrinsic factor B. Hydrogen ions C . Bicarbonates D . Chloride ions 57. Enzymes of the stomach include all these, except: A . Pepsin B. Trypsinogen C . Cathepain D . Gastric renin 58. Acid-neutralising mucus is produced mainly by: A . Surface cells B. Neck cells of gastric glands C . Both D . Neither 59. Which of these is not true of gastrocolic reflex? A . It initiates mass persitalus in the cold B. It is mediated by the sympathetic nerves C . Myenteric plexus is involved in this reflex D . None of the above 53 A 54 B 55 C 56 C 57 B 58 B 59 B 30 MCQS in Physiology 60. Which of these ions is in high concentration in the pancreatic juice? A . Chloridess B. Bicarbonates C . Sulfates D . Hydrogen ions 61. Which of these is absorbed by Pinocytosis? A . Proteins B. Glucose C . Iron D . None of these above 6 2 Which of these forms iron is best absorbed? A . Ferric salts B. Organic iron forms C . Ferrous salts 63. Which of these is true of obstructive jaundice: A . High level of serum alkaline phosphatase B. High levels of conjugated bilirubin C . Both D . Neither 64. Jaundice is clinically evident when the serum bilirubin exceeds: A . 0.5 mg% B. 0.4 mg% C . 2 mg % D . 5mg% 65. Functions of colon include all these except: A . Electrolyte absorption B. B-complex synthesis C . Transit of food residue D . Absorption of aminoacids 66. Wllich of these substances is (are) absorbed by carriermediated transport? A . Glucose B. Aminoacids C . Both D . Neither 60 B 61 A 62 C 63 B 64 C 65 B 66 A Digestive System 31 67. Secretion of pepsin is influenced by the following except: A . Vagal stimulation B. Insulin C . Food in the stomach presence of protein D . Secretin 68. The effective inhibitor of gastric secretion is: A . Entro gastrone B. Somatostatin C . Glucagon D . Cholecysto kinin 69. Stimulus for receptive relaxation of the stomach is: A . Food in the stomach B. Food in the intestine C . Seceretin D . Cholecysto kinin 70. Analyse is secreted by: A . Hepatocytes B. Aoniar cells of pancreas C . Parietal cells of stomach D . Goelet cells 71. Total Removal of pancreas can cause: A . Diabetes mellitus B. Increase in faecal fat content C . Increase in faecal nitrogen content D . All of the above 72. Important function of the Brunners gland secretion is: A . To protect the duodenal mucosa from ulceration B. To provide water and electrolyte C . To secerete gitract hormones D . All of the above 67 D 68 B 69 A 70 B 71 A 32 MCQS in Physiology CHAPTER 6 Kidney 1 . The functional parts of a renal tubule are: A . Proximal convoluted tubule, loop of henle and distal concoluted tubule B. Glomerulus, proximal convoluted tubule, loop of henle and collecting duct C . Bowmans capsule, ascending segment of loop of henle, descending segment and collecting duct D . Proximal convoluted tubule, loop of henle and collecting duct 2 . The cells present in between the endothelium and the basement membrane in the nephron is: A . Macula densa B. Lacis cells C . Podocytes D . Mesangial 3 . The cells found at the angle of the afferent and efferent arterioles are: A . Lacis cells B. Macula densa C . Mesangial cells D . Podocytes 1 A 2 D 3 B Kidney 33 4 . The juxtra glomerular apparatus is formed by: A . Juxtra glomerular cells , macula densa and lacis cells B. Macila densa , mesangial cells and lacis cells C . Juxtra medullary cells, podocytes and macula densa D . Only macula densa and lacis 5 . The epithelial cells that make contact with the capillaries are: A . Mesangial cells B. Macula densa C . Lacis cells D . Podocytes 6 . Proximal convoluted tubule is lined by :: A . Squamous cells B. Cuboidal cells with brush broder C . Columnar cells D . Pseudostratified cells 7 . The capillary endothelium is lined by: A . Carrier protein B. Glycocylated protein C . Conjugated protein D . None of the above 8 . Cells in kidney that have a secretory function include: A . Juxta glomerular cells B. Type I medullary interstitial cells C . Collecting ducts D . All the above 9 . The rate of the blood flowing through both the kidneys of a 70kg man is about: A . 1400ml/min B. 1600ml/min C . 1300ml/min D . 900ml/min 4 A 5 D 6 B 7 B 8 D 9 C 34 MCQS in Physiology 10. From the renal artery, Interlobular arteries and arcuate artery arises: A . Afferent arterioles B. Peritubular capillarie C . Efferent arterioles D . Vasa recta 11. Capillaries of golmerular tuft coalesce to form: A . Afferent arteriole B. Efferent arteriole C . Peritubular capillaries D . Vasa recta 12. The medullary blood supply is by means of: A . Capillary network of afferent arterioles of juxta-medullary glomeruli B. Capillary network of efferent arterioles of juxta-medullary glomeruli C . Peritubular vessels D . None 13. Vasa recta is the branch given off by: A . The afferent arteriole descending into the medulla B. The efferent arteriole descending into the pyramid C . The efferent arteriole descending into the cortex D . The efferent arteriole descending into the pyramid 14. The renal blood flow can be estimated by: A . Plasma clearance of para aminohyppuic acid B. Diodrast clearance C . Both the above are correct (a and b) D . Inulin clearance 15. PAH or diodrast test given the measurement of: A . Renal plasma flow B. Renal blood flow C . Glomerular filtration rate D . Urine formation 10 A 11 B 12 B 13 B 14 C 15 A Kidney 35 16. The renal blood flow is constant over a range of: A . 60 - 80 mm of Hg B. 80-100 mm of Hg C . 80 - 200 mm of Hg D . 60-80 mm of Hg 17. The theories put forward to explain the autoregulation of kidney are: A . Cell separation theory B. Intrarenal pressure theory C . The myogenic theory D . All the above 18. The arrangement of afferent and efferent arterioles favours: A . Low capillary pressure in the glomerular tuft B. Moderate capillary pressure in the glomerular tuft C . High capillary pressure in the glomerular tuft D . None 19. Renin is secreted when blood flows to kidney: A . Remains the same B. Increased C . Decreased D . Intermittent 20. Autoregulation depends macula densa of: A . Sodium B. Calcium C . Potassium D . Magnesium upon the concentration 21. The kidney is richly supplied by: A . Parasympathetic nerves B. Sympathetic nerves C . Splanchnic nerve D . All the above 16 C 17 D 18 C 19 C 20 A 21 B at 36 MCQS in Physiology 22. Prolonged standing: A . Increases the renal blood flow B. Decreases the renal blood flow C . The renal blood flow remains the same D . Fluctuates 23. The cortex of the kidney receives renal blood flow of: A . 90% of total RBF B. 80% of total RBF C . 60% of total RBF D . 70% of total RBF 24. Function of lymph is: A . To return protein reabsorbed from tabular fluid to the blood B. To utilise protein absorbed from blood C . To carbohydrates reabsorbed from the tabular fluid to the blood D . None 25. Decreased water absorption occurs in: A . Diabetes insipidus B. Water diuresis C . Osmotic diuresis D . None of the above 26. Excepting one, all the osmolarity: A . Sodium and chloride B. Haemoglobin C . Albumin D . Glucose in others the proximal determine tabule plasma 27. Cell separation theory postulates that blood flow in renal vessels is by: A . Axial streaming of cells B. Portal system C . Under high pressure D . Autoregulation 22 B 23 C 24 A 25 C 26 B 27 A Kidney 37 28. In A. B. C. D. which part of the kidney cell rich plasma flows? Medulla Superficial parts of the kidney Hilum Renal tubules 29. Intrarenal pressure theory prevents an increase in: A . Glomerular filtration rate B. Renal blood flow C . Autoregulation D . Systemic blood pressure 30. In A. B. C. D. renal blood flow autoregulation forms the basis of: Active vascular tone change in arterioles Vasoconstriction Rise in blood pressure All of the above 31. Renin-angiotensin mechanism role in: A . Autoregulation B. Renal blood flow C . Excretion D . Acid-base balance plays a very important 32. The kidney produces almost as much lymph per minute as: A . Blood B. Water C . Urine D . Creatinine 33. Afferent and efferent pressure in: A . PCT B. Glomerular tuft C . DCT D . Henles loop 28 B 29 B 30 D arterioles 31 A 32 A favour 33 B high capillary 38 MCQS in Physiology 34. Special features of renal circulation are: A . Portal system within B. Autoregulation mechanism C . A Shunts-arterio-venous D . All of the above 35. Henles loop A . Sodium B. Chloride C . Water D . All reabsorbes: 36. Which hormone acts on the distal tubule? A . Antiduretic hormone or vasopressin B. Thyroid hormone C . Cortico sterone D . Adrenaline 37. The permeability of the glomerular capillaries is: A . Same as in other capillaries B. Slightly higher than in other capillaries C . Fifty times higher than other capillaries D . Lower than in other capillaries 38. Capillary bed commonly referred to as high pressure bed is: A . Glomerular capillary bed B. Cortico medullary bed C . Peritubular capillary bed D . None of the above 39. Effective filtration pressure is: A . 15 mm of Hg B. 20 mm of Hg C . 35 mm of Hg D . 62 mm of Hg 40. Glomerular filtration rate is: A . 60 ml/min B. 120 ml/min C . 300 ml/min D . 35 ml/min 34 D 35 D 36 A 37 C 38 A 39 C 40 B Kidney 39 41. Amount of glomerular fluid filtered per day is: A . 120 litres B. 180 litres C . 200 litres D . 50 litres 42. What is completely reabsorbed in the tubular cells? A . Glucose B. Urea C . Uric acid D . Protein 43. Average filtration fraction is approximately: A . 19% B. 25% C . 80% D . 60% 44. Average value of glomerular pressure is about: A . 80 mm Hg B. 75 mm Hg C . 45 mm Hg D . 10 mm Hg 45. Normal intracapular pressure is about: A . 50 mm Hg B. 75 mm Hg C . 25 mm Hg D . 10 mm Hg 46. During sympathetic stimulation of the kidneys: A . Decreases the GFR B. Increases the GFR C . No change in GFR D . Increases urine formation 47. Increases in arterial pressure: A . Increases GFR B. Decreases GFR C . No change in GFR D . First decreases then increase GFR 41 B 42 A 43 A 44 B 45 D 46 A 47 A 40 MCQS in Physiology 48. The basic mechanism of tubular secretion: A . Active transport B. Passive transport C . Passive diffusion D . None 49. Hydrogen ion secretion continue until pH of the tubular fluids falls to: A . 7.4 B. 4.5 C. 3 D . 6.5 50. The rate of H+ secretion is enhanced by: A . Increased CO2 concentration B. Decreased respiration C . Increased metabolic rate D . All of the above 51. The substances secreted tubule are: A . Creatinine B. Drugs like sulpnamide C . Para-amino hipuric acid D . All of the above by the proximal convoluted 52. The substance used for the study of X-ray contrast study of urinary tract is: A . Iodinated compounds B. Radiopaque substance C . Uropac D . All 53. The secretion of Ammonia depends upon the: A . PH of tubular fluid B. PH of blood C . Renal blood flow D . Plasma flow 48 A 49 B 50 D 51 D 52 D 53 A Kidney 41 54. Ammonia secretion mechanism in the kidney helps in: A . Water balance B. Acid-base balance C . Temperature regulation D . Maintaining oncotic pressure 55. The hormone influencing the absorption of Na+ in the DCT is: A . Aldesterone B. Erythropoietin C . Thyroxin D . Renin-Angiotensin 56. The inulin is secret in: A . PCT B. DCT C . Henles loop D . None 57. The secretion of Ammonia helps to reduce: A . The acidity of extracellular fluid B. The alkalinity of extracellular fluid C . The pH of intracellular fluid D . The alkalinity 58. Angiotensin II is a: A . Vasoconstrictor B. Vasoregulator C . Vascodilator D . Coagulant 59. Angiotensin II causes: A . Stimulation of RBC production B. Thirst sensation by direct action on brain C . Formation of vitamin D D . Control of sodium excretion 54 B 55 A 56 D 57 A 58 A 59 B 42 MCQS in Physiology 60. 1:25 Dihydroxychole calciferol is called a hormone because: A . It is produced in kidney and actions are on other target organs B. It is produced in pancreas C . It is produced Adrenal gland which is an endocrine gland D . It is produced by kidney 61. Prostaglandins bring about: A . Fall of medullary blood flow and increase in cortical blood flow B. Fall of cortical blood flow and increase in medullary blood flow C . Fall of both cortical and medullary blood flow D . Increases blood flow of both cortex and medulla 62. Natriuretic hormone may be probably controlling: A . Sodium excretion B. Sodium secretion C . Potassium D . Potassium secretion 63. Pudendal nerves carry superficial sensation from: A . Distal bladder neck B. Adjacent perineal structures C . Dorsal root ganglion D . Both a and b 64. Relaxation of detrusor contraction sphincter helps in: A . Emptying the bladder B. Filling the bladder C . Contraction of the bladder D . All of the above and of deep somatic the internal 65. The sensation of pain, fullness and desire to empty the urine travel through: A . Automatic nervous system B. Central nervous system C . Peripherial nerves D . None of the above 60 A 61 A 62 A 63 D 64 B 65 A Kidney 43 66. The volume pressure curve of the bladder is known as: A . Glomerular filtration curve B. Angiogram C . Cystometrogram D . None 67. Sacral spinal center for the reflex control of micturition exist in: A . Second sacral segment of spinal cord B. Third sacral segment of spinal cord C . Fourth sacral segment of spinal cord D . All the above 68. The visceral afferent endings in the posterior urethra causes: A . Contraction of ext. sphincter B. Relaxation of ext. sphincter C . Relaxation of int. sphincter D . Contraction of int. sphincter 69. In A. B. C. cystometrogram segment I shows: Slight rise in pressure and initial increase in volume Very slow rise in pressure over a considerable range of volume A steep rise in pressure when the volume reaches a critical value D . Only increase in volume 70. The nervous reflex which causes the emptying of urinary bladder is called: A . Bain Bridge reflex B. Micturition reflex C . Abdominal reflex D . Chemoreceptor reflex 71. The bladder receives its sympathetic innervation from: A . Pelvic nerve B. Hypogastric nerve C . Both D . Lumbar 66 C 67 D 68 B 69 A 70 B 71 B 44 MCQS in Physiology 72. External sphincter of the urinary bladder is made by: A . Detrussor muscle B. Perineum muscle-striated muscle C . Smooth muscle D . Myoepithelium 73. Nerves coming from sacral segment to urinary bladder are: A . Sympathetic nerves B. Parasympathetic C . Somatic nerves D . Parasympathetic and Somatic 74. Initial micturation urge is felt when the bladder gets: A . 150ml of urine B. 400ml of urine C . Just before urination D . 600ml of urine 75. Acidosis is: A . Increase of H+ conc. in blood B. Increase of HCO3 conc. in blood C . Absorption of H+ in dct D . Absorption of HCO3¯ in DCT 76. In A. B. C. D. anterior hypothalamic lesion: Starting of micturition is affected Ending of micturition is affected Both None 77. Normal Sp. gravity of urine: A . 1.045 B. 2 C. 5 D . 2.045 78. Abnormality in kidney function can be tested by: A . Urine analysis B. Blood examination C . Intravenous pylography D . All the above 72 B 73 D 74 A 75 A 76 C 77 A 78 D Kidney 45 79. Substance that retards reabsorption of water: A . Osmotic diuretics B. Na+ C . K¯ D . All the above 80. The cellophane allows all the constituents of plasma except: A . H2O B. Organic salts C . Plasma proteins D . None 81. The countercurrent multiple system in kidney helps: A . To form hypertonic urine B. To form dilute urine C . To keep the renal medullary tissue D . In tubular secretion 79 A 80 C 81 A 46 MCQS in Physiology CHAPTER 7 Endocrines and Reproduction 1 . Which of the following substances is NOT essential for synthesis of Thyroid Hormone? A . Iodine B. Thyroglobulin C . Iodide D . Protein-bound iodine 2 . Yellowish tint of the skin in Hypothyroidism is due to: A . Jaundice B. Carotenemia C . Anaemia D . Oedema 3 . Which of the following biological amines is NOT secreted by adrenal medulla? A . Epinephrine B. Dopamine C . Norepinephrine D . Serotonine 1 D 2 C 3 D Endocrines and Reproduction 47 4 . Zona glomerulosa is activated by: A . Only Acth B. Both Acth and Angiothensin C . Only Angiotensin II D . Increased ECF volume 5 . Excess androgen secretion causes: A . Cushings syndrome B. Anreno Genital syndrome C . Conns Syndrome D . Addisons disease 6 . In a Surgically adrenalectomized patient pigmentation of the skin is due to: A . Increased MSH activity B. Decreased cortisol levels in blood C . Decreased ACTH levels in blood D . MSH activity of increased ACTH level in blood 7 . Which of the following is NOT a glycoprotein? A . FSH B. TSH C . Lh D . Growth hormone 8 . The actions of growth hormones are: A . Directly on the bone, cartilage and other tissues B. By the inter action of growth hormones and somatomedin C . Dependent on nutrition of the body D . Through Ca++ 9 . Which of the following hormone is essential for life? A . Cortisol B. Parathormone C . Insulin D . Adrenaline 10. Neuromoscular hyper sensitivity after parathroidectomy is due to: A . Absence of acetyle choline estrase B. Lack of Na+ C . Decreased permeability to K+ D . Increased permeability to Na+ 4 C 5 C 6 D 7 D 8 B 9 C 10 D 48 MCQS in Physiology 11. In A. B. C. D. Untreated Adrenalectomized animal death is due to: Mineral, corticoid deficiency Glucocorticoid deficiency Excess secretion of ACTH Catechol amine deficiency 12. The major adrenal androgen excreted in normal adult is: A . Dehydroopiandrosterone B. 17 - Ketosteroid C . Andro stenedione D . Testosterong 13. Normal menstrual cycle in human is between: A . 28-30 days B. 3 -4 days C . 30-40 days D . One calender month 14. Duration of pregnancy in human is: A . Nine calender months B. Ten lunar months C . 280 days D . All of the above 15. Genadotropic Hormones act on the following EXCEPT: A . Graffin follicle B. Curpus luteum C . Leydig cells D . Ductal system of the mammary gland 16. Amenorrhoea is common: A . In menopause B. During lactation C . During pregnancy D . All of the above 17. Castration means: A . Undesended testis B. Absence of secondary sexual characters C . Removal of testis D . Removal of placenta 11 A 12 A 13 A 14 C 15 D 16 D 17 C Endocrines and Reproduction 49 18. The following are the functions of oestroge except: A . Proliferation of endometrium B. Ductal growth in breast tissue C . Alveolar growth in breast tissue D . Growth of uttering muscle during pregnancy 19. To determine the time of ovulation which of the following test is essential: A . Basal body temperature B. Cervical mucous secretion C . Secretary pattern in biopsy D . All of the above 20. Hormones of protenin in nature cannot be given orally except: A . Adrenalin B. Cortisol C . Thyroxine D . Oxytocin 21. Function of human chorionic gonado tropin is for: A . Detecting pregnancy B. Maintain pregnancy C . Maintain corpus luteum D . Induced abortion 22. Action of sequential contraceptive pill is: A . Induce abortion B. Prevent implantation C . Prevent ovulation D . Prevent fertilization of ova 23. Normal Sperm count is: A . 20-40 million sperms/ml B. 100-120 million sperms/ml C . 15-16 million/ml D . 10-20 million/ml 24. Which of the following factors regulates the pituitary hormone? A . Releasing hormones from hypothalamus B. Negative feedback mechanism C . Positive feedback mechanism D . All of the above 18 C 19 D 20 C 21 C 22 C 23 B 24 D 50 MCQS in Physiology 25. Actions of oxytocin include all the following except: A . Milk injection B. Water re-absorption C . Facilitation of sperm transport D . Parturition 26. Once released ovum is viable upto: A . 48-72 hours B. 5-6 hours C . 5-6 days 27. Extraadrenal actions of ACTh include: A . Stimulation of melanocytes B. Eosinopenia C . Both D . Neither 28. Which of these hormones is not an anabolic hormone ? A . Cortisol B. Growth hormone C . Insulin D . Testosterone 29. Aldosterone seceretion is stimulated by -: A . Hyponatraemia B. Hyperkalaemia C . Both D . Neither 30. Vanillylmandelic acid is a metabolite of: A . Thyroxine B. Adrenaline C . Glucagor D . None of the above 31. Peptide levels are indicators of: A . Insulin B. Glucagon C . Growth hormone D . Cortisol 25 B 26 A 27 C 28 A 29 C 30 B 31 C Endocrines and Reproduction 51 32. Which of these horomones has no action in carbohydrate metabolism? A . Cortisol B. Parathoromone C . Glucagor D . Adrenalime 33. Which of these is known as sulation factor? A . Somatostation B. ADH C . Somatomed in D . Adrenaline 34. Which of these pairs is not an antagonistic pair? A . Insulin and glucagon B. Parathormone and calcitonin C . Growth horomone and adrenaline 35. Which of the following are true of actions of growth horomone? A . Hypoglycemia B. Synthesis of proteins C . Hyperglycemia D . Breakdown of proteins E . A and C F . B and D 36. ACTH has all the following actions except: A . Stimulation of aldosterone secretion B. Stimulation of cortisol secretion C . Eosinopenia D . Stimulation of melonocytes 37. Which of these is an effective stimulus for growth hormone secretion? A . Plasma glucose B. Plasma level of aminoacids C . Plasma calcium D . Plasma sodium 32 B 33 C 34 C 35 F 36 A 37 C 52 MCQS in Physiology 38. In A. B. C. primary hypothyroidism, there is,: Low thyroid hormone and low plasma TSH High plasma TSH and low thyroid hormone Normal plasma TSH and low thyroid hormone 39. Myxoedema is due to: A . Subcutaneous fluid B. Subantaneous fat C . Subantaneous mucophysaceharile 40. Glucagon is secreted by: A . Beta cells of islets B. Alpha cells of islets C . Delta cells of islets 41. Pheochromocytoma is a tumour of: A . Adrenal medulla B. Adrenal cortex C . Testis D . Neurohypephysis 42. Hyperkalaemia stimulates: A . ADH secretion B. ACTH secretion C . PTH secretion D . Aldosterone secretion 43. Exophthalmos is said to be due to the action of: A . T4 B. T3 C . TSH D . LTS 44. In A. B. C. crtinism, mental retardation is due to: Sensory defects Improper myelination Vitamine B12 deficiency 45. Features of Addissons following, except: A . Muscle weakness B. BP hypertension C . Pigmentation D . Hyponatraemia 38 B 45 B 39 C 40 B disease 41 A 42 D include 43 D all of 44 B the Endocrines and Reproduction 53 46. In A. B. C. D. spermatogenesis, meiosis occurs information of: Primary spermatocytes Spermatids Secondary spermatocytes Mature spermatosoa 47. In 28-day cycle, time of ovulation is best expressed as: A . Fourteen days before the onset of next cycle B. Fourteen days after the onset of menses 48. Implantation of the Zygots occurs during the: A . First week after fertilization B. Two weeks after fertilization C . Three Hours after fertilization 49. Healthy sperms retain their motility in the cervical mucus upto (Post-coital test): A . 8 Hours B. 2 hours C . 48 hours D . 24 hours 50. Ferning of the cervical mucus is due to: A . Oestrogen B. Progesterone C . LH D . FSH 51. At the time of ovulation in the basal body temperature there is a: A . Fall B. Increase C . No change 52. Which of these cells produce inhibin? A . Sertoli cells B. Spermatogonis C . Leydig cells D . ASpermatozon 53. Which of these is a natural method of contraception? A . Rhythem (safe period) method B. Oral contraceptives C . Mechanical devices D . Spermicides 46 D 53 A 47 B 48 A 49 C 50 A 51 A 52 A 54 MCQS in Physiology CHAPTER 8 Cardiovascular System 1 . Cardiac muscle functions as a syncitium because: A . Intercalated discs offer least resistance to the passage of impulse B. There is continuity of protoplasm between individual cardiac muscle fibres C . Of increased number of mitochondria in the myocardium D . Cardiac muscle fibres are interconnected by multiple side branches 2 . Summation and tetamisyation are not possible in cardiac muscle because: A . Relative refractory period extends throughout disastole B. Absolute refractory period occupies almost whole of systole C . Excitability of cardiac muscle is increased during supernormal phase D . There is a long latent period in cardiac muscle 1 B 2 B Cardiovascular System 55 3 . The duration of cardiac cycle with a hear rate of 75/mt is: A . 2.0 sec B. 0.3 sec C . 0.8 sec D . 1.5 sec 4 . Cholinergic sympathetic vasodilator fibers: A . Innervate the blood vessels of skeletal muscles B. Cause vasodilation of cerebral blood vessels C . Innervate the renal blood vessels D . Cause vasodilatation of pulmonary blood vessels 5 . Rapid ventricular filling: A . Depends mainly on atrial systole B. Marks the beginning of ventricular relaxation C . Gives rise to third heart sound in healthy people D . Responsible for the production of first heart sound 6 . A-C interval of the phlebogram: A . Represents ventricular systole B. Has a normal duration of 4 to 6 milliseconds C . Is prolonged in atrial fibrillation D . Corresponds to the P-R interval of ECG 7 . The blood flow to the brain in an adult is: A . 300 ml B. 750 ml C . 1200 ml D . 500 ml 8 . In the heart cardiac muscle is not found in the: A . International septum B. Interventricular septum C . Valve msps D . SA Node 9 . In the systemic circulation: A . Artertoles convert the pulsatile blood flow of elastic arteries into a smooth flow B. Blood pressure is zero (atmospheric) in capillaries C . The lowest blood flow is found in the veins D . Energy for circulation is generated only by recoil of the elastic fibres in the big arteries 3 C 4 A 5 C 6 D 7 B 8 C 9 A 56 MCQS in Physiology 10. The C wave of atrial pressure curve is due to: A . Atrial systole B. Ventricular systole C . Atrial Diastole D . Ventricular Diastole 11. Chronotropism refers A . Rhythmicity B. Conductivity C . Excitability D . Contractility to: 12. When the heart rate is 100/min? A . The duration of cardiac cycle is 0.8 second B. The duration of cardiac cycle is 0.6 second C . The ratio of systole : diastole is likely to be 3:5 D . It is pathological 13. Which of the following is not seen during isovolumetric ventricular contraction? A . Steep increase of intraventricular pressure B. The Semilunar valves remaining closed C . Ejection of blood from ventricules D . C waves of JVP 14. In healthy ventricles, the force of contraction: A . Decreases with sympathetic stimulation B. Increase with increased end diastolic volume within physiological limits C . Does not influence the cardiac output D . Is always the same 15. The P Wave in the electorcardiogram: A . Is caused by atrial depolarization B. Is due to atrial repolarisation C . Is absent in atrial hypertrophy D . Occurs during ventricular depolarization 10 B 11 A 12 B 13 C 14 B 15 A Cardiovascular System 57 16. The principle of Einthovens triangle is utilized in: A . Standard limb leads B. Augmented limb leads C . Chest leads D . All of the above 17. When compared to the first heart sound, the second heart sound: A . Is less loud B. Has a longer duration C . Has a higher pitch D . Is less likely to be split during inspiration 18. The vasomotor center: A . Is a collection of neurons in the midbrain B. Acts through the sympathetic nervous system C . Is not active in a healthy person at rest D . Activity is increased as a result of Baroreceptor stimulation 19. Mechanisms which regulate the blood pressure include all the following excepts: A . Baroreceptor reflex B. Renin-Angiotensin mechanism C . Maintance of circulating blood volume D . Releases of substances P from peripheral nerve endings 20. The Peripheral resistance: A . In the pulmonary circulation is less than that in the systemic circulation B. To circulation is mainly found in the capillaries C . Is likely to rise when the sympathetic nervous system is blocked D . Increases significantly during muscular exercise 21. Cutting of vagi in experimental animals results in: A . Increase in heart rate B. Sudden decrease of blood pressure C . Decrease in cardiac output D . A significant increase of peripheral resistance 16 A 17 C 18 B 19 D 20 A 21 A 58 MCQS in Physiology 22. The local factor which causes dilatation of arterioles is: A . Increase in oxygen concentration B. Decrease in tissue PH C . Increase in local temperature D . Stimulation of baroreceptors 23. The blood supply to left ventricle is increased abruptly during which phase of the ventricular cycle? A . Isovolumetric contraction B. Isovolumetric relaxation C . Isotonic contraction D . Diastasis 24. In the triple response: A . White reaction is the first response to be seen B. The flare is due to arteriolar dilatation produced as a result of axon reflexz C . The wheal lasts for about one minute D . Deneravation of the area abolishes all the components 25. Expected finding during muscular exercise include all the following except: A . Increased cardiac output B. Increased blood flow to skeletal muscle C . Decreased coronary blood flow D . Decreased renal blood flow 26. When compared to normal subjects trained atheletes have a: A . Smaller stroke volume B. Faster resting heart rate C . Larger heart D . Decrease in the number of mitochondrian skeletal muscle fibres 27. The normal cerebral blood flow is: A . 950 ml/min B. 50 ml/100gm/min C . 600 ml/min D . 750 ml/min 22 C 23 B 24 B 25 C 26 C 27 D Cardiovascular System 59 28. A patient in the initial compensatory phase following haemorrhagic shock is likely to have the following features except: A . Cold and clammy skin B. Bradycardia C . Fall in systolic blood pressure D . Decreased urinary output 29. The cushing reflex comes into play when: A . There is increased viscosity of vlood B. There is increased cranial pressure C . There is decreased CSF pressure D . There is increased mean Arterial pressure 30. The structures outside the Blood Brain Barrier are all of the following except: A . Neurohypophysis B. Chemoreceptor trigger zone C . Ovlt D . Locus ceruleus 31. The Percentage of cardiac output to the heart is: A . 5% B. 10% C . 25% D . 50% 32. Veno Construction is likely to occur due to: A . Circulating angiotension B. Decrease in tissue PH C . Increase of local temperature D . Stimulation of Baro receptors 33. The tendency for blood flow to be turbulent increases when there is a decrease I in Blood: A . Vessel diameter B. Density C . Flow velocity D . Viscosity 28 B 29 B 30 D 31 A 32 A 33 D 60 MCQS in Physiology 34 . All the features of Purkinje tissue cells in the heart are true except: A . Conduct impulses faster than some neurons B. Are larger than ventricular myocardial cells C . Lead to contraction of the base before the apex of the heart D . Are responsible for the short duration of the QRS complex 35. Ventricular filling: A . Depends mainly on atrial contraction B. Begins during isometric ventricular relaxation C . Gives rise to a third heart sound in some healthy people D . Can occur only when atrial pressure is greater than atmospheric pressure 36. Microcirculation means: A . Circulation through skeletal muscle B. Circulation through the skin C . Circulation through arterioles, meta arteriole, capillaries, small venules D . Circulation through the cerebrum 37. Conditions that cause low resistance shock include the following except: A . Anaphylaxis B. Pulmonary Embolism C . Fainting D . Sepsis 38. The property that is unique to myocardium is as: A . Excitability B. All or none response C . Long absolute refractory period D . Conductivity 39. Myocardial glicose metabolism is mainly: A . Aerobic B. Anaerobic C . Both 34 C 35 C 36 C 37 B 38 C 39 A Cardiovascular System 61 40. Which of these increases the myocardium at a given volume? A . Acetylcholine B. Norepinephrine C . Dopamine D . B and C contractility of the 41. Which of these is responsible for the fourth heart sound? A . Opening of mitral valve B. Atrial Systole C . Opening of semi-lunar Valves D . Rapid ventricular filling 42. Which of these are inversely related, in a healthy heart? (EF=Ejection fraction, EDV=End Diastolic Volume, ESV=End-Systolic volume) A . EF and EDV B. EF and ESV C . Both D . Neither 43. Atrial contraction takes place during the: A . Ventricular isometric relaxation B. Late Ventricular Systole C . Late Ventricular diastole D . None of the above 44. Myocardium is most sensitive to: A . Hypercapnia B. Hypoxia C . Acidemis D . Hyperkalaemia 45. Which of these is a potent vasoconstrictor? A . Bredykinin B. Substance P C . Carbondioxide D . Serotonin 40 B 41 C 42 B 43 C 44 D 45 D 62 MCQS in Physiology 46. Which of the following is a potent vasodilator? A . Serotonin B. Dopomine C . Bradykinin D . Norepinenephrine 47. In juguler venous pulse wave is recorded during atrial systole? A . C Wave B. V Wave C . A Wave 48. Which of these is not true of an arterial pulse? A . Expansile nature B. Better felt than seen C . Better seen than felt D . Well localized 49. Which of these is a vasoconstrictor? A . Renin B. Angiotensinogen C . Angiotensin I D . Angiotensin II 50. Baro receptors of carotid sinus and aortic arch are sensitve to: A . Increase in systolic pressure B. Increase in diastolic pressure C . Increase in arterial pressure D . Increase in pulse pressure 51. Nervous regulation of arteriolar tone is maximal in: A . Coronary arterioles B. Skeletal arterioles C . Cerebral arterioles D . Cutaneous and splanchnic arterioles 52. Which of these principle is mainly concerned regulation of heart rate and blood pressure? A . Munro-kelly Doctrine B. Mareys law C . Starlings law D . None of the above 46 C 47 C 48 C 49 D 50 A 51 D 52 B with Cardiovascular System 63 53. All A. B. C. D. or None law is applicable to: Cardiac muscle Single skeletal muscle fibre Single nerve fibre All of the above 54. Cardiac muscle functions as a single unit because of: A . Automatic inervation B. Gap junctions C . Anatomical syncitium D . Rich blood supply 55. Velocity of conductivity of impulse in the AV node is: A . Decremental B. Same as the ventricular muscle C . Much faster than bundle of His D . Not affected by vagal stimulation 56. Prepotential in SA node is due to: A . Decrease in K+ efflux B. Increase in permeability of Na+ C . Opening of long-lasting calcium channels D . Decrease in K+ efflux and opening of transient calcium channels 57. AV nodal delay is: A . 0.5 Sec C . 0.1 Sec B. 0.3 Sec D . 0.05 Sec 58. Normal heart beat is due to: A . Sinus rhythm B. Nodal rhythm C . Idioventricular rhythm D . Atrial rhythm 59. In A. B. C. D. Sinus arrhythmia the heart rate: Is regular Increase during inspiration Decrease during inspiration Increase during expiration 53 D 54 C 55 A 56 A 57 D 58 A 59 B 64 MCQS in Physiology 60. Sinus arrhythmia is a: A . Pathological condition B. Normal phenomenon C . Disease condition of SA node D . Congential deformity of conduction cyst 61. PA. B. C. D. R interval is abnormally long in: Ist degree heart block Wolff-parkinson white syndrome Lown-Ganong-Levine syndrome Stroke Adams syndrome 62. Cardiac catheterisation is useful for: A . Collecting mixed venous blood sample B. Recording HIS bundle electrogram C . For Studying pressure changes D . All of the above 63. One of the important factors that increases the end diastolic volume is: A . Increase in venous return B. Increase in heart rate C . Decrease in blood volume D . Increase in Na+ conc. in ECF 64. End diastolic volume is: A . 70 ml C . 130 ml B. 90 ml D . 50 ml 65. Capacitance vessels A . Capillaries C . Arteries B. Aorta D . Veins are: 66. The pressure in the great veins at their entrance into right atrium is known as: A . Central venous pressure B. Critical closing pressure C . End arterial pressure D . Effective prefusion pressure 60 B 61 A 62 D 63 A 64 C 65 D 66 A Cardiovascular System 65 67. Blood flow velocity can be measured using: A . Plethys mograph B. Doppler flow meter C . Sphygmo manometer D . Indicator dilution technique 68. The Korotkow sounds are produced by: A . Closure of heart valves B. Rapid blood flow in hear chambers C . Turbulence in the flow of blood in the blood vessle D . Opening of AV valves 69. The normal electrical axis of the heart is? A . 60 B. 0 C . -30 D . 90 70. Which is the fastest conducting part in the conduction system? A . Purkinje fibre B. Bundle of His C . AV node D . SA node 71. The term central venous pressure, refers to pressure in: A . The pulmonary veins B. The vanae cavae and the right atrium C . The pulmonary capillaries D . The left atrium 72. Stroke volume in an adult weighing 70 kg is: A . 70-80 ml. B. 5 lt. C . 3.1 lt. D . 200 ml. 73. Cardiac output in normal adult: A . 2 lt. B. 5 lt. C . 3 lt. D . 8 lt. 67 B 68 C 69 A 70 A 71 B 72 A 73 B 66 MCQS in Physiology 74. End systolic volume is: A . 50-60 ml. B. 130-150 ml. C . 100-120 ml. D . 200 ml 75. a A. B. C. D. wave in jugular venous pressure curve: Precedes QRS complex of ECG Follows QRS complex of ECG Precedes p wave Follows T wave 76. Lovens reflex is: A . Vasodilatation in an active organ and vasoconstriction in other organs B. Vasoconstriction is an active organ and vasodilatation in other organs C . Vasodilatation in both active and inactive organs D . No change in blood supply 77. Peripheral resistance is mainly present in the: A . Veins B. Arteries C . Arterioles D . Capillaries 78. Systolic pressure is directly proportional to: A . Cardiac output B. End systolic volume C . End diastolic volume D . Peripheral resistance 79. During Valsalva manoeuovre the intrathoracic pressure becomes: A . More -ve B. Less -ve C . +ve D . No change 74 A 75 A 76 A 77 C 78 A 79 C Cardiovascular System 67 80. The tension developed in the heart is greatest when the initial length of the sarcoma is: A. 3 u B. 2.2 u C. 5 u D . 10 u 81. Coronary blood flow is maximum during: A . Isometric contraction B. Isometric relaxation C . Rapid ejection D . Rapid filling 82. Which of the following factors relax the precapillary sphincter? A . Hypoxia B. Hypercapnia C . Increase in (H+) D . All of the above E . None of the above 83. Starlings law states that the force of contraction is directly proportional to: A . The tension B. Pressure C . Initial length of muscle fibre D . End systolic volume 84. Third heart sound is due to: A . Opening of AV valves B. Diastolic flow of blood into ventricles C . Opening of semilunar valves D . Blood flow in aorta 85. Administration of adrenaline results in: A . Cutaneous vasodilatation and coronary vasoconstriction B. Cutaneous vasoconstriction and coronary vasodilatation C . Cutaneous and coronary vasodilatation D . Cutaneous and coronary vasoconstriction 86. Atrial contraction contributes to what per cent ventricular filling? A . 10% B. 20% C . 30% D . 40% 80 B 81 B 82 D 83 C 84 A 85 B 86 A 68 MCQS in Physiology 87. Stimulation of sympathetic produces: A . Vasoconstriction of coronary vessel B. Vasodilatation of coronary vessel C . No change D . A and B 88. Hering nerve is a branch of: A . Vagus B. Glossopharengeal C . Facial D . None of the above 89. Axon reflex is due to: A . Symphathetic vasodilators B. Parasymphathetic vasodilators C . Antidromic vasodilators D . All of the above 90. First heart sound coincides (in cardiac cycle) with: A . Isometric contraction phase B. Isometric relaxation phase C . Ejection phase D . Proto diastole 91. p A. B. C. D. wave in ECG is due to: Ventricular depolarisation Auricular repolarisation Septal depolarization Auricular depolarization 92. Stroke volume is: A . EDV-ESV C . Blood volume -EDV B. ESV-EDV D . Cardiac output-EDV 93. Change from the recumbent to erect posture results after 1-2 minutes, in: A . Increase of arterial blood pressure B. Decrease of blood pressure C . No change in blood pressure D . Decrease in venous pressure 87 B 88 B 89 C 90 A 91 D 92 A 93 A Respiration 69 CHAPTER 9 Respiration 1 . The normal respiratory rate in an adult is: A . 12-16/min B. 20-25/min C . 6-10/min D . 25-35/min 2 . The pulmonary surfactant lining the alveoli is produced by: A . Type I alveolar epithelial cells B. Type II alveolar epithelial cells C . APUD cells present in the alveoli D . Pulmonary alveolar macrophages 3 . The amount of air that moves into lungs with each inspiration or the volume of air that moves out with each expiration is called: A . Inspiratory reserve volume B. Expiratory reserve volume C . Tidal volume D . Residual volume 1 A 2 B 3 C 70 MCQS in Physiology 4 . In a normal healthy individual, the physiological dead space is: A . More than anatomic dead space B. Less than anatomic dead space C . Identical with anatomic dead space D . None of the above 5 . The respiratory quotient is the ratio of: A . Volume of CO2 evolved to O2 absorbed per unit time B. Minute volume to tidal volume C . O2 consumption per minute to minute volume D . O2 consumed to arterial O2 content 6 . Total lung capacity: A . Tidal volume + residual volume B. Residual volume + Vital capacity C . Inspiratory capacity + residual volume D . Expiratory reserve volume + residual volume 7 . The normal alveolar ventilation/perfusion ratio is: A . 0.6 B. 0.4 C . 0.2 D . 0.8 8 . The normal ventilation/perfusion distribution is as follows: A . Ventilation more at the base of the lungs B. Perfusion more at the apex of the lungs C . Ventilation more at the apex and perfusion more at the base of the lungs D . Both ventilation and perfusion are uniform throughout the lung fields 9 . CO2 is transported in blood: A . In dissolved form in plasma as bicarbonate B. In combination with plasma proteins C . In combination with Hp D . All of the above forms 4 C 5 A 6 C 7 D 8 D 9 D Respiration 71 10. The partial pressure of O2 in arterial blood is: A . 46 mm Hg B. 40 mm Hg C . 95 mm Hg D . 130 mm Hg 11. The affinity of Hb for O2 is influenced by: A . PH B. Temperature C . Concentral of 2,3, DPG D . All of the above 12. Dyspnoea is usually present when the dyspnocic index is: A . Less than 90% B. Less than 80% C . Less than 70% D . None of the above 13. For cyanosis to occur reduced Hb concentration should be at least: A . 8 G% B. 3 G% C . 5 G% D . 7 G% 14. The solubility of CO2 in the blood is about: A . 0.5 times that of O2 B. 2 times that of O2 C . 20 times that of O2 D . 10 times that O2 15. Decompression sickness or Caissons disease is due to bubbling of: A . Oxygen in the tissues B. CO2 in the tissue C . Hydrogen in the tissues D . Nitrogen in the tissues 10 C 11 D 12 C 13 C 14 C 15 D 72 MCQS in Physiology 16. Compensatory mechanism due to acclimatization at high attitude involves: A . Increased alveolar ventilation B. Increased production of red blood cells C . Production of alkaline urine D . All of the above 17. Positive G can be prevented by: A . Pressurized bags applied around abdomen and legs B. Tensing abdominal muscles C . Positioning the body so that gravity acts perpendicularly D . All of the above 18. If both vagi are cut: A . Inspiration is prolonged B. Expiration is prolonged C . No change in rhythmic respiration D . Respiration stops 19. The apneustic center stimulates: A . Inspiration B. Expiration C . Vagus D . Respiration muscles 20. In A. B. C. D. histotoxia hypoxia: O2 tension in blood is low O2 content of blood is low O2 utilization by tissues is excessive O2 utilization by tissues is defective 21. Chemical regulation of respiration is maximally affected by: A . O2 B. CO2 C . Bicarbonate D . Lactic acid 22. Respiration during exercise is regulated by: A . Cerebral cortex B. Hypoxia in the muscles C . Joint proprioceptors D . All of the above 16 D 17 D 18 A 19 A 20 D 21 B 22 D Respiration 73 23. Nitrogen wash out or simple breath oxygen method directly measures: A . Total lung capacity B. Functional residual capacity C . Vital capacity D . Inspiratory capacity 24. Following are features of emphysema except: A . Narrowing of airway due to lose of elastic tissue B. Barrel-shaped chest C . Hypoxia due to perfusion of underventilated alveoli D . The vital capacity is increased 25. The respiratory centre: A . Is situated in the reticular substance of lower part of pons B. Is influenced by higher centers C . Is inhibited during swallowing D . All of the above statements are true 26. In A. B. C. D. inspiration the following changes occur, except: The diaphragmatic comes become flatter The costal muscles are drawn in The dimensions of thorax are increased The intrapleural pressure falls 27. During forced expiration, which of these does not occur: A . Intrapleural pressure rises B. Small alveoli empties into big alveoli C . Small airways is closed D . Big alveoli empties into small alveoli 28. Hering-Breuer reflex is activated during: A . Early inspiration B. Maximal inspiration C . Late expiration D . None of the above 29. Acute hypoxia has all these effects, except: A . Hyperventilation B. Bone marrow stimulation C . Vasoconstriction in tissues D . Cardiac stimulation 23 B 24 D 25 D 26 B 27 B 28 B 29 C 74 MCQS in Physiology 30. If Va : Q is more than 1, it implies: A . Venuous shunt B. Physiological dead space C . Neither 31. Stimulation of J receptors produces: A . Bronocho-construction and hyperventilatory effort B. Broncholdialation C . Hypoventilation D . Dyspnoed E . A and D F . B and C 32. Peripheral chemoreceptors are located in: A . Carotid sinus B. Carotid body C . Aortic sinus D . Aortic body E . A and C F . B and D 33. All A. B. C. D. of these stimulate O2 dissociation, except: 2,3 DPG Increase in PH Hypercapnia Fal in PH 34. Normal arterial PCO2 (PaCO2) is: A . 38 mmHg B. 46mmHg C . 52 mmHg D . 40 mmHg 35. In A. B. C. D. cheyne-stokes breathing aponoea results from: Hypoxia Hypercapnia Acidosis Hypocapnia 30 B 31 B 32 F 33 B 34 D 35 D Respiration 75 36. Pneumotaxic Centre: A . Is situated in the medulla B. Inhabits the apneustic centre C . Stimulates the inspiratory center D . Inhabits the expiratory center 37. Compliance of lungs and chest wall, together is about: A . 0.5 1/cmH2O B. 11/cm H2O C . 0.221/cm H2O D . 0.11/cm H2O 38. The intrapleural pressure, during quiet inspiration, is about: A . -2 mm Hg B. -0 mm Hg C . -6 mm Hg D . +4 mm Hg 39. Valsalva manouever is: A . Forccd expiration against closed glott is B. Doop inspiration with closed glott is C . Both D . Neither 40. A A. B. C. D. respiratory unit consists of: A terminal bronchiole and alveoli A segmental bronchus and its branches and alveoli A lobar bronchus, its branches and alveoli None of the above 41. In A. B. C. D. inspiration the following changes occur, except: The diaphragmatic domes become flatter The costal muscles are drawn in The dimension of thorax are increased The intrapleural pressure falls 42. Which of these muscles are involved in quiet inspiration: A . Abdominal muscles B. Serratus anterior C . Internal intercostals D . None of the above 36 C 37 B 38 C 39 A 40 A 41 B 42 D 76 MCQS in Physiology 43. In A. B. C. D. airway obstruction, which of these occurs: The FEV1 is prolonged The residual volume is increased Both Neither 44. Consolidation of the lungs involves: A . Fluid in the lung parenchyma B. Fibrosis of the lung tissue C . Dilatation of alveoli D . All of the above 45. Airway irritation receptors are responsible for: A . Cough reflex B. Enhanced depth of inspiration C . Both D . Neither 46. Which of these is not a useful test in detecting airway obstruction: A . Tidal volume B. FEV1 C . FRC D . All the above 47. Haldane effect relates: A . CO2 uptake on O2 dissociation B. O2 dissociation on CO2 uptake C . CO2 uptake and (H+) D . O2 delivary and (H+) 48. Peripheral chemoreceptors are located in: A . Carotid sinus B. Carotid body C . Aortic sinus D . Aortic body E . A and C F . B and D 43 C 44 A 45 C 46 A 47 B 48 F Respiration 77 49. All A. B. C. D. of these stimulate O2 dissociation, except: 2,3 DPG Increase in pH Hypercapnia Fall in pH 50. In A. B. C. D. E. F. restrictive lung diseases: FEV1 is normal FEV1 is increased VC is diminished VC is normal A and C B and D 51. Normal residual volume is: A . 0.5 l B. 1.5 l C . 11 D . 200 ml 49 B 50 E 51 C 78 MCQS in Physiology CHAPTER 10 Nervous System: Special Senses 1 . The appetite center is located in: A . Ventromedial hypothalamus B. Lateral hypothalamus C . Mamillary bodies D . None of the above 2 . The thermostate of the hypothalamus is situated in: A . Mamillary bodies B. Prooptic nudei C . Porterior hypothalamus D . Lateral hypothalamus 3 . Amacarine cells are found in the: A . Internal ear B. Skin C . Retina D . Muscle spindle 1 B 2 C 3 C Nervous System: Special Senses 79 4 . Motor aphasia results from lesions in: A . Area 4 B. Area 44 C . Area 6 D . Area 39 5 . Granular cells are predominant in: A . Sensory cortical areas B. Motor cortical areas C . Both D . Neither 6 . Which of these is not a strech reflex? A . Ankle jerk B. Crossed extensor reflex C . Jaw jerk D . Bicees jerk 7 . Demeyelination results from deficiency of: A . Vitamin B6 B. Vitamin B12 C . Vitamin A D . Vitamin D 8 . Rectilinear acceleration A . Organ of corti B. Utricle-saccule C . Semicircular canals D . None of the above stimulates: 9 . The EEG rhythm of awake, relaxed, eyes closed state is: A . Beta B. Theta C . Alpha D . Delta 10. Functions of hypothalamus include all, except: A . Control of temperature B. Control of muscle tone C . Control of autonomic functions D . Control of food intake 4 B 5 A 6 B 7 A 8 C 9 C 10 B 80 MCQS in Physiology 11. Tuberal nuclei of hypothalamus are mainly concerned with release of: A . CRF B. PIF C . Both D . Neither 12. Cortico-Fronto cerebellar tract is related to: A . Paleocerebellum B. Neocerebellum C . Archicerebellum 13. Alpha block occurs when the eyes: A . Close B. Open C . Both D . Neither 14. Tremor of Parkinsons disease is due to: A . Hyperactivity of cholingergic neurons B. Hyperactivity of dopaminergic neurons C . Both D . Neither 15. The neurotransmitters in bascal ganglia are: A . Depamine B. Acetyicholine C . Seroterrin D . All of the Above 16. Which of these is not a neutrotransmitter ? A . GABA B. Glutamic acid C . Asportate D . Tyrosine 17. Which of these is not a primary odour? A . Ethireal B. Musky C . Putrefying D . Camphorous 11 A 12 B 13 B 14 A 15 A 16 D 17 D Nervous System: Special Senses 81 18. Which of these is not a primary colour ? A . Red B. Yellow C . Green D . Blue 19. The best audible frequency range for man is: A . 150 - 500 hz B. 500 - 2500 hz C . 3000 - 5000 hz D . 50 - 100 hz 20. Delta waves are characteristic of: A . Stage 1 sleep B. Stage 4 sleep C . FfmM sleep D . None of the above 21. Kluver-Buey syndrome results from lesions of: A . Prefrontal B. Cingulate gyri C . Temporal lobes D . Corpus callosum 22. Which of these is not true of right cerebral hemisphere? A . It is non-dominant in right handed people B. Its speech areas are non-functional C . The parietal areas are responsible for spatial orientation sense 23. Myelin sheath is derived from: A . Schwann cells B. Oligo dendroglia C . Both D . Neither 24. Equilibrium potential for K+ is: A . -90 mV B. -70 mV C . +35 mV D . +40 mV 18 B 19 B 20 B 21 C 22 C 23 B 24 B 82 MCQS in Physiology 25. Positive action potential (after potential) is due to: A . Entry of Ca++ ions B. Efflux of K++ ions C . Entry of Na++ ions D . Entry of Cl¯ ions 26. C fibres -: A . Conduct impulse much faster B. Are non-myelinated C . Are not susceptible to hypoxia 27. Saltatory conduction -: A . Occurs in non-myelinated nerve fibres B. Occurs in myelinated nerve fibres C . Velocity is slower than non-salutatory conduction 28. Which of the following sensations is generated by nacked nerve endings? A . Pain B. Cold C . Hearing D . Muscle tension 29. Pacinian corpuscles are -: A . A type of temerature receptor B. Pain receptor C . Touch pressure receptor 30. Symptoms of Parkinsons disease include all these except: A . Intension tremor B. Mask-like face C . Pill-rolling movements D . Drooping shuffling gait 31. Chronaxie is the duration of stimulus needed, when the current strength is: A . Twice the rheobase B. Equal to rheobase C . Twice or more than rheobase D . Twice or less than rheobase 25 C 26 B 27 B 28 A 29 C 30 A 31 A Nervous System: Special Senses 83 32. Which of these is not a superficial reflex? A . Corneal reflex B. Abdominal reflexes C . Jaw jerk D . Planter reflex 33. Which of these is seen in upper motor neuron lesions? A . Babinskis sign B. Loss of abdominal reflex C . Both D . Neither 34. Double decussation relates to: A . Ventral sprine - cerebellar tracts B. Dentato - rubral and rubro - spinal C . Medial Lemnesoi D . Pyramidal tracts 35. Visceral pain: A . Shows relatively rapid adaptation B. Is mediated by B fibres in the dorsal roots C . Is referred to superficial region 36. In A. B. C. upper motor neuron lesion: Muscle tone is increased Muscle tone is decreased Muscle tone normal 37. Infrafusal fibres are innervated by: A . Alpha motor neuron B. Gamma motor neuron C . Reushaw cell 38. Doctrine of specific nerve energies was proposed by: A . Henry head B. Charles Sherrington C . Muller D . Penfield 32 C 33 C 34 D 35 C 36 A 37 B 38 C 84 MCQS in Physiology 39. All A. B. C. D. these are true of cones, except: They are responsible for photopic vision They are responsible for colour vision They have rhodopsin They are maximal in the macula 40. Contralateral homonymous hemianopia results lesions of: A . Optic nerve B. Occiptial cortex C . Optic chiasma D . Optic tract 41. All A. B. C. D. these changes occur during dark adaptation, except: Retinal sensitivity decreases Purkinge shift occurs Visual pigments regenerates Pipils of dialates 42. Impedence matching is between: A . External meatus and tympanic membrane B. Tympanic membrane and oval window C . Two ears D . Oval window and round window 43. Which of these are first order neurons? A . Optic nerves B. Olfactory nerves C . Tractus solitanus D . Lateral lemniscus 44. Which of these are not true of rods? A . They are responsible for scotopic vision B. They are concentrated in the macula C . They contain rhodopsin D . They are absent in the fovea 45. Lateral lemsisous fibre relay in the: A . Superior colliculi B. Inferior colloculi C . Medical gericulate bodies D . Lateral gericulate bodies 39 C from 40 D 41 A 42 B 43 B 44 A 45 C Nervous System: Special Senses 85 46. The taste area in the thalamus is located in the: A . VPM nucleus B. VPL nucleus C . Pulvinar D . Dorsolateral thalamus 47. In A. B. C. D. Aigyll Robertson pupil: Light relax is intract Accommodation reflex is intact Both reflexes are lost Both reflexes are intact 48. Function of tympanic membrane is regulated by: A . Tensor tyampani B. Tensor palati C . Stapedius D . Annuler ring of tympanic membrane 49. Complete dark adaption takes: A . 5 mins B. 20-30 mins C . 10 seconds D . 60 mins 50. Area 42 is located in the: A . Superior temporal gyrus B. Inferior temporal gyrus C . Occupital cortex D . Anterior post and temporal cortex 51. Pyramidal tract arises from: A . Area 4 B. Area 4,6,8,3,1,2,19 C . Area 9,10,11,12 D . Area 41,42 52. Which thalamic nucleus is associated with the paper circuit? A . Pulvinar B. Ventro postero lateral nucleus C . Medial genuiculate body D . Anterior thalamic nucleus 46 B 47 B 48 A 49 B 50 A 51 B 52 D 86 MCQS in Physiology 53. The site of lesion in Parkinsonism is in the: A . Subthalamic nucleus B. Candate nucleus C . Substantia nigra D . Lateral thalamus 54. Righting reflexes are integrated at the level of: A . Medulla B. Spinal cord C . Cerebral cortex D . Mid brain 55. Decerebrate rigidity is due to the unbalancd action of: A . Pyramidal tract B. Vestibulo spinal tract C . Recticule spinal tract D . Rubro spinal tract 56. The site for short term memory is the: A . Lateral temporal cortex B. Hippocampus C . Prefrontal cortex D . Parietal cortex 57. Which of these cells forms a blood brain, barrier ? A . Obgodendroglia B. Microglia C . Astroglia D . Schwann cells 58. Resting membrane equilibrium of: A . Potassium B. Sodium C . Chlorides D . Calcium potential is dependent on the 59. Which of these is not seen in upper motor neuron lesion? A . Babinskis B. Clonus C . Hypotonia D . Exaggerated jerks 53 C 54 C 55 A 56 B 57 C 58 A 59 C Nervous System: Special Senses 87 60. Hypertonia on pyramidal lesions is of the: A . Lead pipe variety B. Clasp knife variety C . Cogwheel variety D . None of the above 61. Neurotransmittor junction is: A . Acetyl choline C . Dopamine released as skeletal neuromuscular B. Noradeenaline D . Astropine 62. Sensations carried in posterior columns include all these, except: A . Epicritic B. Deep pain C . Vibration D . Superficial pain 63. Rhombergs sign is positive in lesions of: A . Posterior colums B. Cerebellum C . Both D . Neither 64. In A. B. C. Brown Sequards syndrome, below the level: Touch is blunted on the side of lesion Touch is blunted on the opposite side of lesion Neither 65. Which of these is essential for nerve regeneration? A . Schwann cell B. Neurofibromma C . Both D . Neither 66. The velocity of conduction of nerve impulse myelinated of fibres is about: A . 0. 5-2 metres/sec B. 1-2 km/sec C . 20-100 metres/sec D . 2-5 metres/sec 60 B 61 A 62 D 63 C 64 B 65 A 66 C 88 MCQS in Physiology 67. The sodium pump mechanism is located in the: A . Cell nuclcus B. Nacleolus C . Cytoplasm D . Cell membrane 68. The IPSP is due to: A . Increased permeability to potassium B. Decreased permeability to sodium C . Increased permeability to chloride D . Decreased permeability to chloride 69. Epicritic perception of pain occurs at the level of: A . Thalamus B. Area 3, 1, 2 C . Area 5,7 D . Pulvinar 70. Aphasia is often associated with hemiplegia in lesions of the: A . Right internal capsule B. Left internal capsule C . Both D . Neither 71. Which of these is characteristic of pyramidal lesions? A . Absence of abdominal reflex B. Lead pipe rigidity C . Clasp knife spasticity D . A and c 72. The putative neurotransmitter of pain is: A . Substance P B. Bradykinin C . Actetylcholine D . K+ ions 73. The neurotransmitter in nigro-striatal tract is: A . Acetylocholine B. Dopamine C . Serotonin D . Adrenaline 67 D 68 C 69 B 70 B 71 D 72 A 73 B Nervous System: Special Senses 89 74. The most slowly adapting encapsulated cutaneous mechanoreceptors with no resting discharge are: A . Ruffini nerve endings B. Merkel disks C . Pacinian corpuscles D . Meissner corpuscles 75. Tactile sensibility includes each of the following except: A . Tactile discrimination B. Tactile localization C . Appreciation of thermal sensibility D . Appreciation of light, touch and pressure 76. In A. B. C. D. the spinal cord, earliest to receive myelination is: Fibres of posterior columns Corticospinal tract fibres Spinocerebellar tract fibres Axons of association pathways 77. Concerning the generator potential, each of the following is correct except that it is: A . A graded non-propagatory potential B. Abolished by removal of encapsulation of the receptor C . Of either polarity D . Generated at the first node Ranvier 78. Anterior hypothalamus is primarily associated with: A . Sexual drive B. Biological rhythms C . Body temperature regulation D . Regulation of feeding behaviour 79. Putative neurotransmitter associated with presynaptic δ ) pain fibres in the inhibition of (type C and type A-δ spinal cord is: A . Dopamine B. Encephalin C . Substance P D . Serotonin 74 B 75 C 76 A 77 B 78 A 79 B 90 MCQS in Physiology 80. When blood flow to your arm is obliterated for a while, a temporary loss of touch-pressure sensibility (with no loss of prick pain and temperature sensibility) is often observed. This could result from the conduction blockade of: A . A-δ fibres B. A-δ fibres C . C- fibres D . B-fibres 81. Which of the following conditions is regarded as primary hyperalgesia? A . Herpes zoster B. Trigemunal neuralgia C . Sunburnt skin D . Thalamic syndrome 82. Each of the following can elicit visceral pain, except: A . Spasm of the ureters B. Spillage of gastric juice into abdominal cavity C . Obliteration of blood flow to viscera D . Cutting through parietal peritoneum 83. Of the cutaneous mechanoreceptors, the best suited to encode the information regarding vibration (at> 250 Hz) sense is: A . The Ruffini endings B. The Merkel disks C . The meissner corpuscles D . The Pacinian corpuscles 84. Each of the following is related to withdrawal reflex, elicited by cutaneous nerve stimulation except: A . Reciprocal contraction of contralateral extensors B. Reciprocal inhibition of ipsilateral extensors C . Involvement of group II primary afferents D . After - discharges 85. The fast, sharp pain sensation, caused by thermal or mechanical stimuli, is mediated by: A . A-α fibres B. A-δ fibres C . B- fibres D . C-fibres 80 A 81 C 82 B 83 D 84 C 85 B Nervous System: Special Senses 91 86. In primates, which reflex recovers first from the spinal shock? A . Scratch reflex B. Withdrawal reflex C . Knee jerk D . Positive supporting reaction 87. Pyramidal lesions are characterized by the: A . Reeling gait B. Spastic gait C . Both D . Neither 88. Endogenous chemical substances that excite pain fibres directly include: A . Serotonin B. Histamine C . Bradykinin D . Prostaglandins 89. Brain receives somatosensory A . Spinothalamic tract B. Leminiscal system C . Both D . Neither information through: 90. The REM-sleep may be evoked by the electrical stimulation of: A . Raphe system B. Suprachiasmatic nucleus of hypothalamus C . Preoptic area of hypothalamus D . Ascending reticular activating system 91. Each of the following is associated with paradoxical sleep except: A . Very low muscle tone B. Synchronized EEG C . Increased brain metabolism D . Rapid eye movements 86 C 87 B 88 D 89 C 90 A 91 B 92 MCQS in Physiology 92. The conditioned - stimulus in the classical experiments of Pavlov was: A . The secretion of saliva B. The placement of meat in the mouth C . The smell of meat D . The ringing of bell 93. Each of the following regarding the anterior lobe of the cerebellum (cat or dog) are correct except: A . Its ablation results in extensor rigidity B. Its stimulation abolishes pre-existing decerebrate rigidity C . Its stimulation enhances decerebrate rigidity D . Its regulator of reflex muscular activity 94. Pick the correct statement: A . Mossy fibres originate from deep cerebellar nucleus B. Purkinje cells project on to basket cells C . Climbing fibres originate from inferior olivary nucleus D . Granule cells receive climbing fibre input 95. Which of the following is least likely to occur, when you are rotated about the vertical axis ? A . Nystagmus and vertigo B. Nausea, vomiting and pallor C . Eyes move in the direction of rotation D . Reactions of the neck and leg muscles 96. Spontaneous vertical nystagmus is suggestive of: A . A disease of labyrinth B. A lesion of the brain stem C . A lesion of vestibular nerve D . None of the above 97. If the midbrain reticular formation is destroyed, sparing the main ascending sensory pathways, the animal: A . Exhibits high amplitude slow waves in the EEG B. May have regular sleep-wake cycles C . May have spontaneous behavioural arousal D . May run into a state of prolonged wakefulness 92 D 93 C 94 D 95 C 96 B 97 A Nervous System: Special Senses 93 98. What happens when tension on biceps muscle is maximum? A . The Ia afferents from the muscle are less active B. The lb afferents discharge from the muscle increases C . Both D . Neither 99. Cholinergic postganglionic sympathetic vate: A . Sweat glands B. Blood vessels in skeletal muscle C . Both D . Neither neurons 100.The system of dopaminergic neurons: A . Originate chiefly from subthalamic neurons B. Inhabit neurons of caudate nucleus C . Both D . Neither 101.CSF pressure is the lying down posture is: A . 20-50 mm B. 50-150 mm C . 150-200mm D . 200-300mm 102.Energy for the brain in starvation is from: A . Glucose B. Ketones C . Fatty acids D . Amino acids 103.Neurotransmitter in Nigrostrial pathway is: A . Dopamine B. GABA C . Acetyl chloride D . Norepinephrine 104.The satiety center is located in the: A . Dorsomedian nucleus of hypothalamus B. Ventromedian nucleus of hypothalamus C . Perifonical region D . Lateral hypothalamic area 98 C 99 C 100 D 101 B 102 A,B 103 A 104 B inner- 94 MCQS in Physiology 105.The frequency of alpha waves in EEG is: A . 8 to 12 cycles/sec B. 15 to 25 cycles/sec C . 2 to 5 cycles/sec D . None of the above 106.Crude touch sensations are carried by: A . Lateral spinothalamic tract B. Ventral spinothalamic tract C . Posterior columns D . Pyramidal tracts 107.Transection of medullary pyramid results in: A . Hypotonia B. Atrophy of muscles C . Forced grasping D . positive babinski sign 108.Temoporal lobe lesion causes: A . Homonymus upper quadrantinopia B. Homonymus lower quadrantinopia C . Bitemporal hemianopia D . Binasal hemianopia 109.Vomiting center is situated in the: A . Hypothalamus B. Amygdala C . Pons D . Medulla 110.Pain producing substance is: A . Serotonin B. Substance P C . Histamine D . Acetyl choline 111.CSF is principally secreted by: A . Choroid plexus B. Arachnoid granulation C . Floor of fourth ventricle D . periaqueductal grey 105 A 106 B 107 D 108 A 109 D 110 B 111 A Nervous System: Special Senses 95 112.Paccinian corpuscles are major receptors for: A . Pressure B. Pain C . Touch D . Temperature 113.Delta waves in EEG are seen in: A . Deep sleep B. REM sleep C . Awake with eyes open D . Awake with eyes closed 114.CSF in comparison blood contains all except: A . Lower calcium B. Lower chloride C . Lower sodium D . Lower cells 115.The electroencephalographic (EEG) curves are called: A . ABCDE Curves B. Bergers Rhythm C . Neurogenic Rhythm D . REM 116.Which of the respiratory volumes cannot be measured by simple spirometer? A . Vital capacity B. Expiratory reserve volume C . Inspiratory capacity D . Tidal volume E . Functional residual capacity 117.The surfactant material lining the lung alveoli: A . Decreases the surface tension of alveolar fluid B. Increase the compliance of lungs C . Has increasing less effect, the more lungs are inflated D . Is decreased when pulmonary blood flow is interrupted E . All the above 112 A 113 A 114 B 115 B 116 E 117 E 96 MCQS in Physiology 118.Normal hepatic blood flow per minute is: A . 50 cc/100 gm of liver tissue B. 100 cc/100 gm of liver tissue C . 200 cc/100 gm of liver tissue D . 300 cc/100 gm of liver tissue 119.The Hemlholz theory of colour vision states that: A . There are three kinds of cones in the retina responding to the three primary colours B. There are two kinds of cones called dominators and modulators C . There is only one kinds of cone and the colour is recognized only in area 17 D . There are seven types of cones responding to the seven colours of the spectrum 120.The cerebellum: A . Has a totally inhibitory output from its cortex B. Has only excitatory signal output from its deep nuclear layers C . Has a conscious interpretation of motor activity D . Has inhibitory influence on muscle tone in humans 121.The condition known as REM sleep is: A . That point at which the individual becomes aware and alert B. Referred to as paradoxical sleep C . Characterized by total lack of all muscular activity D . Characterized by slow high voltage regular EEG activity 122.Red colour blindness is called: A . Deuteranopia B. Protanopia C . Protanomaly D . Deuteranomaly 123.True visceral pain arise from: A . Distension B. Mechanical irritation C . Excessive heat D . Compression E . Chemical stimulation 118 A 119 A 120 A 121 B 122 B 123 A Nervous System: Special Senses 97 124.The receptors in retina for those of blue, green and red waves lengths are called: A . Modulators B. Trichomators C . Dominators D . None of these 125.Which of the following statements is not true? A . Decorticate rigidity is greater than decerebrate rigidity B. Righting reflexes are absent in the decerebrate animal C . Visual righting reflex is present in a thalamic animal D . Decorticate rigidity is seen only when the animal is at rest 126.Where is motor activity probably initiated in the brain? A . Motor cortex B. Premotor cortex C . Basal ganglia D . Cerebellum 127.The optical power of the eye is: A . 25 Dioptres B. 50 Dioptres C . 60 Dioptres D . 75 Dioptres 128.The percentage of pyramidal fibres which are unmyelinated: A . 20 B. 35 C . 50 D . 75 129.Blood brain barrier is made up of: A . Astrocytes B. Oligodendrocytes C . Oligodendroglia D . Microglia 130.In A. B. C. D. Parkinsonism, tremor is: 6 to 8 per second 2 per second 2 to 4 per second Uncountable 124 A 125 A 126 C 127 C 128 C 129 A 130 A 98 MCQS in Physiology 131.Destruction of lateral nucleus of thalamus lead to: A . Aphagia B. Hyperphagia C . Satiety D . Somnolence 132.For A. B. C. D. cerebral flow to be doubled, PCO2 should be: 40 mm Hg 80 mm Hg 100 mm Hg 200 mm Hg 133.Brocas area: which is true: A . Present bilaterally in brain B. Supplied by MCA C . Lesion causes Laryngeal palsy D . Present in the temporal lobe 134.Hypothalamus regulates all except: A . Food intake B. Temperature C . Anticipatory rise in heart rate D . Hypophysis 135.First change to occur after nerve cut is: A . Schwan cell mitosis B. Axonal sprouting C . Myelin sheath degeneration D . Nuclear disintegration 131 B 132 B 133 B 134 C 135 C Published by Jitendar P Vij Jaypee Brothers Medical Publishers (P) Ltd EMCA House, 23/23B Ansari Road, Daryaganj New Delhi 110 002, India Phones: 3272143, 3272703, 3282021 Fax: 011-3276490 e-mail: jpmedpub@del2.vsnl.net.in Visit our website: http://www.jpbros.20m.com Branches • 202 Batavia Chambers, 8 Kumara Kruppa Road, Kumara Park East, Bangalore 560 001, Phones: 2285971, 2382956 Tele Fax: 2281761 e-mail: jaypeebc@bgl.vsnl.net.in • 282 IIIrd Floor, Khaleel Shirazi Estate, Fountain Plaza Pantheon Road, Chennai 600 008, Phones: 8262665 Fax: 8262331 e-mail: jpmedpub@md3.vsnl.net.in • 4-2-1067/1-3, Ist Floor, Balaji Building, Ramkote, Cross Road Hyderabad 500095, Phone: 6590020, 4758498 Fax: 4758499 e-mail: jpmedpub@hyd.vsnl.net.in • 1A Indian Mirror Street, Wellington Square Kolkata 700 013, Phone: 2451926 Fax: 2456075 e-mail: jpbcal@cal.vsnl.net.in • 106 Amit Industrial Estate, 61 Dr SS Rao Road, Near MGM Hospital Parel, Mumbai 400 012 , Phones: 4124863, 4104532 Fax: 4160828 e-mail: jpmedpub@bom7.vsnl.net.in MCQs in Human Physiology © 2002, NM Muthayya All rights reserved. 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