Pharmacology Medication List Medication Name: Brand Tylenol Medication Name: Generic Classification Action Adverse Effects Nursing Process Considerations Acetaminophen Non opioid Fever; management of mild pain Rash; Steven Johnson Syndrome Proventil; Ventolin; ProAir Albuterol Bronchodilator: Beta 2 Agonist Treatment or prevention of bronchospasm in obstructive airway disease Tremor, nervousness, insomnia, nausea, headache, cough Limit to <4g/day in adults; Avoid use with renal and liver impairment; consumption of alcohol with administration increases liver damage risk potential Decrease of serum digoxin levels; caution with MAOI and Tricyclic Antidepressant admin Fosamax Alendronate Biphosphate Osteoporosis; Paget Disease Norvasc Amlodipine Anti – Anginal: Calcium channel blocker HTN; CAD; Angina Edema; pulmonary edema; headache, fatigue Patient education: take only in AM with full glass of water; Do not chew tablet; Do not lie down for 30 minutes post administration Monitor for symptomatic hypotension/peripheral edema; use with caution with hepatic impairment Other Teach patient to rinse mouth after use If diet intake is inadequate: consider vitamin D and calcium supplement Aspirin – ASA Aspirin Non opioid; Anti-platelet Pain; Fever; acute coronary syndrome Tenormin Atenolol Beta Blocker: Beta 1 selective Lipitor Atorvastatin Statin: lipid lowering agent HTN; angina pectoris; post MI; alcohol withdrawal syndrome; thyrotoxicosis Hypercholesteremia Altreza; atropine PO; SalTropine Atropine Anticholinergic; anti-spasmodic Spastic conditions of GI tract Cipro Ciprofloxacin Infection Decadron Dexamethasone Antibiotic: Fluroquinolone Glucocorticoid; Antiinflammatory Inflammation, cerebral edema, allergic conditions Hepatotoxicity; hearing loss; tinnitus; platelet aggregation inhibition Fatigue; hypotension; cold extremities; postural hypotension Diarrhea; nasopharyngitis; arthralgia; UTI; nausea Headache; tachycardia; arrhythmia; flushing; dizziness Nausea, abdominal pain, diarrhea, Bradycardia, dry skin, rash, decreased glucose tolerance, Cushing Syndrome, CHF in susceptible patients Discontinue if tinnitus occurs; Avoid in pediatrics due to Reyes syndrome Should be taken with food or full glass of water to avoid GI upset Ischemic heart disease can be exacerbated with abrupt discontinue; Must be weaned off under MD supervision Risk or myopathy in elderly; elevated blood sugars; reversible cognitive effects Contraindicated in narrow angle glaucoma; use with caution with open angle glaucoma; BPH; CVD; hepatic/renal impairment May exacerbate myasthenia gravis Impaired wound healing; elevated BP and blood sugars; fluid retention Monitor for rash Lanoxin Digoxin Antidysrhythmics; inotropic agent Heart Failure Dizziness; mental disturbance; diarrhea; n/v; rash Benadryl Diphenhydramine Antihistamine Allergic reaction, insomnia, motion sickness, parkinsonism Sedation, confusion, anticholinergic effects Colace Docusate sodium Stool softener; laxative Constipation Aricept Donepezil Cholinesterase inhibitor Dementia; Alzheimer’s Disease Abdominal cramping, diarrhea, intestinal obstruction, throat irritation Nausea; diarrhea; insomnia; infection; headache; fatigue; anorexia; abnormal dreams Lovenox Enoxaparin Anti-coagulant DVT; abdominal surgery; knee/hip replacement surgery Hemorrhage; thrombocytopenia Use with caution: myocarditis; severe bradycardia, severe pulmonary disease, thyroid disease, renal disease; caution with diuretic administration May cause sedation; effects increased with alcohol consumption; use with caution in angle closure glaucoma, prostatic hypertrophy, peptic ulcer Do not use for longer than 7 days; excessive use may result in dependence; monitor for bleeding Risk for GI bleed; may exaggerate muscle relaxation during surgery; use with caution with history of seizures Monitor for hematoma; monitor for s/s of neuro impairment Therapeutic range: 0.5-2 ng/ml May decrease cognitive function in geriatric patients Iron: Feosol Ferrous Sulfate Iron product; supplement Iron deficiency anemia Constipation; contact irritation; nausea; tooth and urine discoloration Hypokalemia; hyperuricemia; dizziness; hearing impairment; hypotension; muscle cramps EPS symptoms; dystonia; muscle stiffness; tardive dyskinesia; sedation; weight gain Lasix Furosemide Diuretic: Loop Edema; resistant HTN; pulmonary edema; increased ICP; hypermagnesemia Haldol Haloperidol Anti-psychotic Psychosis; schizophrenia; Tourette Disorder Heparin Heparin Anti-coagulant DVT; PE; Acute coronary syndrome; STEMI/NSTEMI; catheter (IV/CVC) patency HIT (heparin induced thrombocytopenia); hemorrhage HCTZ Hydrochlorothiazide Diuretic: thiazide HTN; edema; HTN in heart failure Anorexia, confusion, fatigue, GI upset, hepatoxicity, hyperglycemia, hypotension Monitor for dark stools; monitor for GI hemorrhage and irritation; Monitor electrolyte levels; monitor intake and output; Food delays absorption; possibility of skin sensitivity to sunlight Use with caution with dementia due to increased mortality with use; Monitor cardiac rhythm; avoid use in narrow angle glaucoma and bone marrow suppression Do not use in DIC/HIT patients; monitor therapy with routine PTT; cardiac monitoring – may prolong PT Monitor: calcium, potassium, magnesium; use with caution in DM and severe renal disease Lower dosing may be needed in geriatric patients Vicodin, hycet, Lorcet,Norco Hydrocodone Opioid analgesic Moderate to severe pain Sedation, bradycardia, dizziness, fatigue, euphoria, mood changes, stupor Headache; flu like symptoms; dyspepsia; hypokalemia; peripheral edema LFT increase; appetite loss; n/v; stomach pain; fatigue; hyperreflexia Dizziness; flushing; headache; hypotension; orthostatic hypotension Lantus Insulin Glargine Anti-diabetic: long acting insulin DM: type 1 and 2 Isoniazid Anti-TB Active/latent TB Imdur Isosorbide Anti-anginal Angina Pectoris Toradol Ketorolac Non opioid analgesic: NSAID Moderate to severe acute pain Headache; insomnia; GI pain; nausea; dizziness; increased BUN/creatinine Enulose; Constulose; Generiac lactulose Laxative (osmotic); ammonium detoxicant Constipation; portal systemic encephalopathy Dehydration; diarrhea; hypernatremia; hypokalemia; n/v Monitor for respiratory depression; use of benzos/alcohol may result in profound sedation Monitor for hypoglycemia Avoid alcohol/drug use; Give with B6 in pregnancy; alcohol will decrease serum medication levels Do not use with acute MI or heart failure; monitor for CNS depression; discontinue with blurred vision May increase risk of thrombotic cardia event; May cause serious GI events (bleeding) with long term use Monitor for abdominal cramping/distension; monitor for electrolyte imbalance Consider what may increase/decrease need for insulin Patient education needed on s/s of hepatitis Patient should not change brands Elderly patients at increased risk for bleeding Decreased response when used with antibiotics Levaquin levofloxacin Antibiotic: fluroquinolone Infection n/v; headache; diarrhea; dizziness; vaginitis Synthroid Levothyroxine Thyroid hormone Hypothyroidism; myxedema coma; organ preservation Prinvil; Zestril Lisinopril Anti – HTN: ACE Acute MI; HTN; heart failure Humalog Lispro insulin Anti-diabetic: Insulin – rapid acting DM: type 1 and 2 Lomotil Loperamide Anti-diarrhea Diarrhea Ativan Lorazepam Benzodiazepine; anti-convulsant Anxiety; insomnia; sedation; status epilepticus Angina pectoris; arthralgia; CHF; flushing; MI; palpitations; diarrhea; anxiety; heat intolerance; weight loss Dizziness; cough; headache; hyperkalemia; diarrhea; hypotension; fatigue; chest pain Severe hypoglycemia; nasopharyngitis; flu like symptoms; headache; pain; infection Anticholinergic effects; blurred vision; sedation; n/v Sedation; fatigue; confusion; SI; vertigo; EPS Monitor for allergic reactions; monitor for hepatoxicity; monitor for peripheral neuropathy Routine lab monitoring Monitor kidney and liver enzymes Monitor blood glucose; monitor potassium levels; s/s of hypoglycemia decreased with beta blockers Monitor for jaundice, respiratory depression; monitor electrolytes Monitor for respiratory depression Less effective in African American population Encourage appropriate fluid intake Glucophage Metformin Anti-diabetic DM type 2 Diarrhea; myalgia; URI; GI upset; low serum B12; n/v; chest discomfort Demerol Meperidine Opioid analgesic Acute pain Reglan Metoclopramide Anti-emetic Flagyl Metronidazole Anti-parasitic GERD; diabetic gastroparesis; chemo induced n/v; post op n/v Anaerobic bacterial infection; STD; bacterial vaginosis Morphine; MS Contin; Duramorph Morphine Opioid analgesic Acute and chronic severe pain Agitation; angina; bradycardia; coma; constipation; dizziness; euphoria; hypotension; MI; n/v Fatigue; sedation; headache; dizziness; somnolence Candidiasis; appetite loss; diarrhea; n/v; ataxia; furry tongue; metallic taste Urine retention; pruritis; n/v; somnolence; constipation Narcan Naloxone Opioid antagonist; opioid reversal agent Opioid overdose Abrupt reversal may cause n/v, tachycardia, increased BP; shivering Monitor for lactic acidosis; avoid alcohol consumption due to increased lactate metabolism Monitor for respiratory depression; Avoid concurrent use with MAO/alcohol/benzos Use for acute pain for less than 48 hours due to neuro risks Monitor for tardive dyskinesia; do not use in epilepsy patients Increased risk for mental depression Superinfection with prolonged use; avoid alcohol during and for 3 days post med completion; may cause gynecomastia Monitor for respiratory depression; alcohol may increase sedation Opioid withdrawal may be life threatening including arrest, seizures, hyperactive reflexes Do not start in patients 80 years of age and older Macrobid; Macrodantin Nitrofurantoin Antibiotic: UTI Nitro Bid; Nitro Dur; Nitro Mist Nitroglycerin Anti-anginal: nitrate Angina Pectoris (long term prophylaxis); CHF Humulin N; Novolin N NPH insulin Anti-diabetic DM: type 1 and 2 Prilosec Omeprazole PPI Duodenal ulcer; H pylori infection; GERD; erosive esophagitis Zofran Ondansetron Anti-emetic n/v; post op n/v; post chemo and radiation n/v Pyridium Phenazopyridine Analgesic; urinary dysuria Anorexia; arthralgia; CDiff; dizziness; fatigue; chills; cough Headache; hypotension; tachycardia; dizziness; xerostomia; n/v Hypoglycemia; hypokalemia; muscle weakness; edema; tremor; hunger Headache; abdominal pain; diarrhea; n/v; URI Headache; fatigue; malaise; drowsiness; diarrhea Headache; vertigo; pruritis; GI upset; skin discoloring; kidney stones; hepatic/renal toxicity Avoid long term use in the elderly; protect from light Discontinue with blurred vision; protect from light; avoid in narrow angle glaucoma and severe anemia Monitor for hypoglycemia; Reduced dosage with liver disease; increased risk for CDiff, salmonella, and campylobacter; monitor magnesium levels Monitor for sedation/hypotension; reduce dose with hepatic impairment Do not use for longer than 2 days with concurrent antibiotic administration Bacterial super infections may occur with long term use Treat headache with ASA or Tylenol Consider what may increase/decrease need for insulin Stop if rash or joint pain occurs Give after food to minimize GI upset; education about urine color change Dilantin Phenytoin Anti-epileptic Seizures Drowsiness; Decreased bone fatigue; ataxia; density with long term headache; slurred use; routine drug level speech; dysarthria; monitoring; Monitor gingival hyperplasia vitamin D, calcium, and (peds); paresthesia phosphorus levels Asthma; ITP; Fluid retention; Prolonged use arthritis; TB; Crohns; electrolyte associated with autoimmune imbalance; infection; latent TB hepatitis; HTN/bradycardia; may be reactivated; inflammation hiccups; increased use methylprednisone appetite and with liver impairment weight gain GERD; benign Headache; Adjust dose with gastric ulcer; abdominal pain; renal/hepatic esophagitis; alopecia; confusion; impairment hypersecretory diarrhea; n/v; conditions anemia; constipation Prednisone Glucocorticoid Zantac Rantidine Histamine H2 antagonist Humulin R, Novolin R Regular insulin Anti-diabetic DM: type 1 and 2 Headache; flu like symptoms; hypoglycemia; dyspepsia; diarrhea; back pain; hypokalemia Monitor for hypoglycemia; monitor potassium; routine blood glucose monitoring Gas X; mylicon; phazyme Simethicone Anti-flatulent Gas retention in GI tract Loose stools May cause false negative gastric guaiac test Therapeutic range: 1020mcg/L (total) Consider what may increase/decrease need for insulin Januvia Sitagliptin Anti-Diabetic DM: type 2 only Aldactone Spironolactone Diuretic Diovan Valsartan Anti-HTN: ARB Vanocin Vancomycin Antibiotic: glycopeptide Infection Coumadin Warfarin Anti-coagulant Venous thrombosis; DVT; PE Diarrhea; headache; constipation; peripheral edema; nausea; URI Primary Gastric bleeding; hyperaldosteronism; ulceration; gastritis; edema; essential urticaria; HTN; CHF; hyperkalemia; hypokalemia; hyponatremia; hirsutism hypovolemia; lethargy; mental confusion HTN; Heart failure; Dizziness; increased Post MI; BUN; hyperkalemia; fatigue; hypotension; viral infection; vertigo N/v; abdominal pain; hypokalemia; diarrhea; pyrexia; UTI; peripheral edema; fatigue; ototoxicity Hemorrhage; taste disturbance; anemia Dose adjustment for renal/hepatic impairment; Contraindicated for type 1 DM; avoid in patients with hx of pancreatitis Monitor electrolyte levels; monitor for sedation/confusion; monitor for s/s of bleeding Monitor renal function and electrolyte levels; monitor for s/s of hypotension; adjust dose in CHF therapy with use of diuretics d/t hypotension risk Monitor renal function; avoid extravasation (infiltration of IV); monitor for hypotension Do not use in pregnancy Routine PT/INR monitoring Maintain INR of 2.0-3.0