Cell division (1.6) Cell division (1.6) [22 marks] 1. What is the sequence of stages during the cell cycle? A. B. G1 → S → mitosis → G1 → → G2 → G2 → mitosis → cytokinesis G2 → cytokinesis → S → mitosis S → cytokinesis C. G1 D. G1 → G2 → mitosis → cytokinesis → S (Total 1 mark) 2. What is produced as a result of mitosis? A. Two cells, each containing half the number of chromosomes of the original cell B. Two cells, each containing the same number of chromosomes as the original cell C. Four cells, each containing the same number of chromosomes as the original cell D. Four cells, each containing half the number of chromosomes of the original cell (Total 1 mark) 3. The diagram below shows a cell during mitosis. What are the structures and stage of mitosis? Stage of mitosis Structure I Structure II A. metaphase chromatid nuclear membrane B. anaphase centromere plasma membrane C. anaphase chromatid nuclear membrane D. metaphase centromere plasma membrane (Total 1 mark) Cell division (1.6) 4. Which of the following does not occur during interphase? A. Replication B. Translation C. Cytokinesis D. An increase in the number of mitochondria (Total 1 mark) 5. What happens during the G2 stage of interphase? A. Homologous chromosomes pair B. Synthesis of proteins C. Homologous chromosomes separate D. Replication of DNA (Total 1 mark) 6. Which of the following take(s) place during either interphase or mitosis in animal cells? I. Re-formation of nuclear membranes II. Pairing of homologous chromosomes III. DNA replication A. I only B. I and II only C. II and III only D. I and III only (Total 1 mark) 7. The graph below represents the amount of DNA during the cell cycle. Which part of the graph represents metaphase? (Total 1 mark) Cell division (1.6) 8. 9. Which of the following statements correctly distinguishes between cytokinesis in animals and plants? A. Animal cells use vesicles to build plasma membranes to separate the daughter cells whilst plant cells construct a cell plate. B. Animal cells form a cleavage furrow as the cell membrane is pulled inwards whilst plant cells use vesicles, to form a cell plate, which eventually fuses with the existing plasma membrane to separate the cells. C. Animal cells construct a plasma membrane with microfilaments whilst plant cells use vesicles to form a new plasma membrane. D. Animal cells use contractile proteins to separate the plasma membrane whilst plant cells build a cell wall upon which the new plasma membranes are formed. Explain how cyclins affect control the progression of a cell through the cell cycle. ................................................................................................................................................ ................................................................................................................................................ ................................................................................................................................................ ................................................................................................................................................ ................................................................................................................................................ ................................................................................................................................................ ................................................................................................................................................ ................................................................................................................................................ (4) Cell division (1.6) 10. The following sequence of pictures, made using an electronic imaging technique, shows a cell undergoing division. [Adapted by permission from Macmillan Publishers Ltd, Fuller, B G et al. 2008. “Midzone activation of aurora B in anaphase produces an intracellular phosphorylation gradient”. Nature. Vol 453.] (a) State the stage of mitosis typified by image II. ...................................................................................................................................... (1) (b) List two processes that involve mitosis. ...................................................................................................................................... ...................................................................................................................................... (2) 11. Cancers form as the result of uncontrolled cell division. (c) State the types of gene that need to be mutated for a tumour to form. ...................................................................................................................................... (1) (c) List three different types of mutagen. ...................................................................................................................................... ...................................................................................................................................... ...................................................................................................................................... (3) (c) Distinguish between primary and secondary tumours ...................................................................................................................................... ...................................................................................................................................... ...................................................................................................................................... ...................................................................................................................................... (2)