Growth assessment/prediction Importance of growth prediction • Maximum skeletal response can be achieved at specific growth stage. • Growth can be promoted when it is rapidly occuring. • Growth can be restrained/ redirected during active period. • Growth modification can eliminate the need of orthognathic surgery. • Orthognathic surgery can be performed when active growth period is completed. Methods Hx and Examination Investigations Lateral cephalogram Cervical vertebral maturation stages Hand-wrist radiograph OPG tooth mineralization stages Hormone levels in blood Cervical Vertebral Maturation stages • Methods ▫ Baccetti ▫ Hassel and Farmen Baccetti method • 6 stages • Presence of concavities at the inferior border of C-2, 3, 4. • Shape changes in C-3, C-4 CS-1 • Flat inferior border of C2,3,4 • Maximum skeletal growth of the midface occur. • Maxillary advancement can be performed in this stage. CS-2 • Concavity at the inferior border of C2 • Flat inferior surfaces of C3,4 • Peak mandibular growth will occur ONE year after the start of this stage. CS-3 • Concavity at the inferior border of C2,3 • Flat inferior border of C4 • Start of Peak mandibular growth • Functional appliance therapy for skeletal Cl II can be initiated in this stage CS-4 • Concavity at the inferior border of C2,3, 4 • Shape of C3,4 Rectangular Horizontal • Decrease in sagittal growth velocity • Significant vertical growth occur CS-5 • Deep notches at the inferior border of C2,3,4 • Shape of C3,4 more squarish • Most of Craniofacial growth is completed • Placement of endosseus implants for missing teeth can be performed. CS-6 • Deep concavities at C2, 3, 4 • Shape of C3,4 at least one has vertical rectangular morphology. • Any individual with >20years of age should be considered in CS-6 stage. • Growth of Craniofacial region is completed • Orthognathic surgery can be planned in this stage. Hand-Wrist Radiograph • Fishman’s skeletal maturity indicators • Appearance of sesamoid bone ▫ start of growth spurt • Fusion of epiphysis with diaphysis ▫ Distal, medial and proximal phalanx of 3rd finger ▫ End of growth spurt ▫ Fusion of radius epiphysis with diaphysis growth completion Tooth developmental Stages • Mandibular canine • Root development ▫ <1/2 start of growth spurt ▫ Apical closure end of growth spurt • Mandibular 2nd molar ▫ Root development upto bifurcation area start of growth spurt. Other investigations • • • • Hormone levels in blood GH IGF-I (insulin-like growth factor) Sex hormones ▫ Testosterone ▫ Estrogen